Evaluation of serum immunoglobulins among individuals living near six Superfund sites.

abstract：:Dietary vitamin E affects the susceptibility of mice and rats to ozone and nitrogen dioxide, suggesting a free radical mechanism of toxicity. Conventional peroxidation does not completely explain the effects of alterations of lung fatty acid composition on both nitrogen dioxide and ozone toxicity. A new scheme is prop...

journal_title：Environmental health perspectives

authors： Menzel DB

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Lead (Pb) exposure has been associated with a host of pathological conditions in humans. In rodents Pb exposure has been shown to alter the hypothalamic-pituitary-adrenal (HPA) axis function. OBJECTIVE:We investigated the effects of lead on responses of the HPA axis to a psychosocial laboratory stressor adm...

journal_title：Environmental health perspectives

authors： Fortin MC,Cory-Slechta DA,Ohman-Strickland P,Nwankwo C,Yanger TS,Todd AC,Moynihan J,Walton J,Brooks A,Fiedler N

更新日期：2012-02-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are persistent pollutants that are ubiquitous in the food chain, and detectable amounts are in the blood of almost every person in most populations that have been examined. Extensive evidence from animal studies shows that PCBs are neurotoxins, even at low doses. Interpretation of huma...

journal_title：Environmental health perspectives

authors： Longnecker MP,Wolff MS,Gladen BC,Brock JW,Grandjean P,Jacobson JL,Korrick SA,Rogan WJ,Weisglas-Kuperus N,Hertz-Picciotto I,Ayotte P,Stewart P,Winneke G,Charles MJ,Jacobson SW,Dewailly E,Boersma ER,Altshul LM,Heinzow B

更新日期：2003-01-01 00:00:00

abstract：:The main source of cadmium in the diet is cereal or meat, especially in liver and kidney. Since the cadmium in both liver and kidney is bound to metallothionein, a heat-stable protein, the gastrointestinal absorption and metabolism of cadmium metallothionein (CdMt) was studied in detail. The selective renal cadmium de...

journal_title：Environmental health perspectives

authors： Cherian MG

更新日期：1979-02-01 00:00:00

abstract：:This report reviews the recent literature on the adverse effects of occupational factors on fertility and related reproductive outcomes. Few studies fulfill the criteria of good study design because of small sample size, insensitive measures of effect, selection, recall, and observation bias, weak if any control of co...

journal_title：Environmental health perspectives

authors： Baranski B

更新日期：1993-07-01 00:00:00

abstract：:An increase in both the numbers and types of tumors found in finfish and shellfish has been noted in the past several decades. In many cases, while the increase in tumor incidence can be correlated with increases in aquatic toxicant levels, causality cannot be definitively proven. One recent epidemiologic investigatio...

journal_title：Environmental health perspectives

authors： Van Beneden RJ

更新日期：1994-12-01 00:00:00

abstract：:Children are uniquely vulnerable to toxic chemicals in the environment. Among the environmental toxicants to which children are at risk of exposure are endocrine disruptors (EDs)--chemicals that have the capacity to interfere with hormonal signaling systems. EDs may alter feedback loops in the brain, pituitary, gonads...

journal_title：Environmental health perspectives

authors： Landrigan P,Garg A,Droller DB

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:The potential impact of microwave radiofrequency electromagnetic fields (RF-EMF) emitted by wireless communication devices on neurocognitive functions of adolescents is controversial. In a previous analysis, we found changes in figural memory scores associated with a higher cumulative RF-EMF brain dose in ad...

journal_title：Environmental health perspectives

authors： Foerster M,Thielens A,Joseph W,Eeftens M,Röösli M

更新日期：2018-07-23 00:00:00

abstract：:Large quantities of food processing, crop, forestry, and animal solid wastes are generated in the United States each year. The major components of these wastes are biodegradable. However, they also contain components such as nitrogen, human and animal pathogens, medicinals, feed additives, salts, and certain metals, t...

journal_title：Environmental health perspectives

authors： Loehr RC

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:Fine particulate matter (FPM) in ambient air causes premature mortality due to cardiac disease in susceptible populations. OBJECTIVE:Our objective in this study was to determine the most influential FPM components. METHODS:A mouse model of atherosclerosis (ApoE-/-) was exposed to either filtered air or con...

journal_title：Environmental health perspectives

authors： Lippmann M,Ito K,Hwang JS,Maciejczyk P,Chen LC

更新日期：2006-11-01 00:00:00

abstract：:Organophosphates in increasing amounts and wider varieties of molecular structure are being used to replace the organochlorine pesticides. It has been assumed that the organophosphates as a class would have a minimal chronic toxicity due to rapid hydrolysis and an unfavorable partitioning as regards to lipids. The phy...

journal_title：Environmental health perspectives

authors： Freed VH,Haque R,Schmedding D,Kohnert R

更新日期：1976-02-01 00:00:00

abstract：:Haloalkane toxicity originates from attack on biological targets by reactive intermediates derived from haloalkane metabolism by a hemoprotein, cytochrome P-450. Carbon-centered radicals and their peroxyl derivatives are most likely involved. The reactions of iron porphyrin--a model for cytochrome P-450--with various ...

journal_title：Environmental health perspectives

authors： Brault D

更新日期：1985-12-01 00:00:00

abstract：:It has been previously established that lung cancer could be induced in rats by exposure to radon and radon daughters. Although the oat-cell carcinomas that are common in humans were not found in rats, other histological types of lung carcinomas, especially squamous cell carcinomas and primitive lung adenocarcinomas, ...

journal_title：Environmental health perspectives

authors： Monchaux G,Morlier JP,Morin M,Chameaud J,Lafuma J,Masse R

更新日期：1994-01-01 00:00:00

abstract：:Many naturally occurring and man-made chemicals present in the environment possess estrogenic activity. Examples include plant and fungal products, pesticides, plasticizers, and other agricultural and industrial chemicals. These environmental estrogens as well as endogenous ovarian estrogens are thought to initiate th...

journal_title：Environmental health perspectives

authors： Stancel GM,Boettger-Tong HL,Chiappetta C,Hyder SM,Kirkland JL,Murthy L,Loose-Mitchell DS

更新日期：1995-10-01 00:00:00

abstract：:The industrial accident that occurred in the town of Seveso, Italy, in 1976 exposed a large population to substantial amounts of relatively pure 2,3,7,8-tetrachlorodibenzo-p-dioxin. Extensive monitoring of soil levels and measurements of a limited number of human blood samples allowed classification of the exposed pop...

journal_title：Environmental health perspectives

authors： Bertazzi PA,Bernucci I,Brambilla G,Consonni D,Pesatori AC

更新日期：1998-04-01 00:00:00

abstract：:While the rat pancreas is susceptible to experimental cancer induction, the spontaneous incidence of pancreatic cancer in this species is reported to be very low. However, we observed unusually high incidences of focal acinar hyperplasia and acinar adenoma in vehicle control male F344/N rats of some NCI/NTP 2-year tox...

journal_title：Environmental health perspectives

authors： Boorman GA,Eustis SL

更新日期：1984-06-01 00:00:00

abstract：:In vivo bone lead measurement using K X-ray fluorescence (KXRF) has been used to estimate long-term lead exposure, especially in adults. Relatively few studies have been conducted on young subjects with this technique. To explore the measurement variability of KXRF bone lead measurements in young subjects, the tibiae ...

journal_title：Environmental health perspectives

authors： Hoppin JA,Aro A,Hu H,Ryan PB

更新日期：2000-03-01 00:00:00

abstract：:A few animal studies on the possible carcinogenic effect of magnetic fields have been published. They have been designed to reveal a possible tumor promotion obtained by applying continuous or pulsed alternating fields at flux densities varying between 0.5 microT and 30 mT on mice or rats initiated with different init...

journal_title：Environmental health perspectives

authors： Holmberg B

更新日期：1995-03-01 00:00:00

abstract：:Embryonal carcinoma (EC) cells offer an interesting model system for evaluating differentiation because the cells are pluripotent, thus resembling germ cells and embryonic stem cells, and because a number of agents have been defined that are capable of promoting the differentiation of these cells. This chapter examine...

journal_title：Environmental health perspectives

authors： Astigiano S,Sherman MI,Abarzúa P

更新日期：1989-03-01 00:00:00

abstract：:A combined cytogeneticurine metabolite analysis approach was used to assess potential interactive effects between Fenarimol (FN), a fungicide, and trichloroethylene (TRI), a halogenated solvent. FN was demonstrated to selectively induce P450-2B1 isoforms in different organs of treated mice. Since the rate of metabolis...

journal_title：Environmental health perspectives

authors： Hrelia P,Maffei F,Vigagni F,Fimognari C,Flori P,Stanzani R,Cantelli Forti G

更新日期：1994-11-01 00:00:00

abstract：:32P-Postlabeling analysis and enzyme-linked immunosorbent assay (ELISA) have been used to detect DNA adducts in peripheral blood lymphocytes from primary aluminum production plant workers who were exposed occupationally to a mixture of polycyclic aromatic hydrocarbons (PAHs). Preliminary results reported here are from...

journal_title：Environmental health perspectives

authors： Schoket B,Phillips DH,Poirier MC,Vincze I

更新日期：1993-03-01 00:00:00

abstract：:There is widespread concern regarding the safety of silver-mercury amalgam dental restorations, yet little evidence to support their harm or safety. We examined whether mercury dental amalgams are adversely associated with cognitive functioning in a cross-sectional sample of healthy working adults. We studied 550 adul...

journal_title：Environmental health perspectives

authors： Factor-Litvak P,Hasselgren G,Jacobs D,Begg M,Kline J,Geier J,Mervish N,Schoenholtz S,Graziano J

更新日期：2003-05-01 00:00:00

abstract：:Organochlorines are persistent lipophilic compounds that accumulate in Inuit people living in circumpolar countries. Organochlorines accumulate as a result of the Inuits' large consumption of sea mammal fat; however, available data are limited to blood lipids, milk fat, and adipose tissue. We report results of organoc...

journal_title：Environmental health perspectives

authors： Dewailly E,Mulvad G,Pedersen HS,Ayotte P,Demers A,Weber JP,Hansen JC

更新日期：1999-10-01 00:00:00

abstract：:A series of experiments is described in which operant methodology is used to study the effects of drugs on "learning." Emphasis is placed on the technique of repeated acquisition as a behavioral baseline for studying this type of transition state. In this technique, each subject is required to learn a new discriminati...

journal_title：Environmental health perspectives

authors： Thompson DM,Moerschbaecher JM

更新日期：1978-10-01 00:00:00

abstract：:In numerous in vivo systems it has been shown that diets high in menhaden oil (a fish oil high in omega-3 fatty acids) can inhibit the carcinogenic process. In the present study, we have assessed the effects of a diet containing menhaden oil on 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA adduct formation in targe...

journal_title：Environmental health perspectives

authors： Schut HA

更新日期：1994-10-01 00:00:00

abstract：:Comamonas testosteroni YZW-D was isolated from Passaic River sediment for its ability to degrade isophthalate and terephthalate. Degradation of the two isomeric compounds proceeds via separately inducible catabolic pathways that converge at protocatechuate. Analysis of the catabolic pathways by which these two isomers...

journal_title：Environmental health perspectives

authors： Wang YZ,Zhou Y,Zylstra GJ

更新日期：1995-06-01 00:00:00

abstract：:Our desire to understand the potential adverse human health effects of environmental chemical exposure has coincided with an increased understanding of the immune system and an appreciation of its complex regulatory network. This has spawned a broad interest in the area of immunotoxicology within the scientific commun...

journal_title：Environmental health perspectives

authors： Luster MI,Rosenthal GJ

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Environmental heat exposure is a public health concern. The impacts of environmental heat on mortality and morbidity at the population scale are well documented, but little is known about specific exposures that individuals experience. OBJECTIVES:The first objective of this work was to catalyze discussion o...

journal_title：Environmental health perspectives

authors： Kuras ER,Richardson MB,Calkins MM,Ebi KL,Hess JJ,Kintziger KW,Jagger MA,Middel A,Scott AA,Spector JT,Uejio CK,Vanos JK,Zaitchik BF,Gohlke JM,Hondula DM

更新日期：2017-08-01 00:00:00

abstract：:Studies of DNA base sequence alterations have shown that for every agent the mutagenic process is specific with respect to the types of base changes induced and the location of the changes in the DNA. Analysis of the types of mutations produced by mutagenic agents can provide insight into the mechanism of mutation and...

journal_title：Environmental health perspectives

authors： Skopek TR,Wood RD,Hutchinson F

更新日期：1985-10-01 00:00:00

abstract：:In this study, we explored the efficacy of upper-room ultraviolet germicidal irradiation (UVGI) in reducing the concentration of Serratia marcescens and Mycobacterium bovis bacille Calmette-Guérin (BCG) aerosols in enclosed places. We constructed a facility (4.5 m x 3 m x 2.9 m) in which both ceiling- and wall-mounted...

journal_title：Environmental health perspectives

authors： Ko G,First MW,Burge HA

更新日期：2002-01-01 00:00:00