Interactive effects between trichloroethylene and pesticides at metabolic and genetic level in mice.

abstract：:Our work has focused on the determination of physiological traits that may facilitate in situ degradation of xenobiotic compounds by indigenous microorganisms. For this our interests center on the following questions: What are the ambient conditions in a benzene, toluene, ethylbenzene, and xylene (BTEX)-contaminated a...

journal_title：Environmental health perspectives

authors： Olsen RH,Mikesell MD,Kukor JJ,Byrne AM

更新日期：1995-06-01 00:00:00

abstract：:I examined non-Hispanic Black and non-Hispanic White differences in exposure to noncriteria air pollutants in 44 U.S. Census Bureau-defined metropolitan areas with populations greater than one million, using data on air toxics concentrations prepared for the U.S. Environmental Protection Agency as part of its Cumulati...

journal_title：Environmental health perspectives

authors： Lopez R

更新日期：2002-04-01 00:00:00

abstract：:The neurochemical basis of memory has been approached experimentally in four different ways: the bioassay; the interventive approach; the interventive-correlative approach; and the correlative approach. These approaches are fundamentally similar to those used for the study of the chemistry of any behavior. Each of the...

journal_title：Environmental health perspectives

authors： Dunn AJ

更新日期：1978-10-01 00:00:00

abstract：:Metals have been mined and used since ancient times. The industrial era has seen a sharp increase in both the amounts and variety of metals that find applications in industry. The inadvertent release of metals, such as from fossil fuel consumption, also adds to the global burden. A number of catastrophic outbreaks hav...

journal_title：Environmental health perspectives

authors： Clarkson T

更新日期：1995-02-01 00:00:00

abstract：:Two remote maritime populations were evaluated for their biological exposure to organochlorines in 1989-1990. Because of their high intake of seafood, these two populations have high biological levels. One hundred nine breast milk samples from Inuit women from Arctic Québec were analyzed to determine levels of polychl...

journal_title：Environmental health perspectives

authors： Dewailly E,Ryan JJ,Laliberté C,Bruneau S,Weber JP,Gingras S,Carrier G

更新日期：1994-01-01 00:00:00

abstract：:In previous attempts to model disposition of 1,3-butadiene in mice and rats, parameter values for 1,2-epoxybut-3-ene metabolism were optimized to reproduce elimination of this gas from closed chambers. However, each of these models predicted much higher concentrations of circulating epoxybutene than were subsequently ...

journal_title：Environmental health perspectives

authors： Kohn MC,Melnick RL

更新日期：2000-10-01 00:00:00

abstract：:The purpose of the study was to determine whether the risk of childhood acute lymphoblastic leukemia (ALL) associated with drinking water disinfection by-products was modified in the presence of variants in genes involved in the metabolism of trihalomethanes (THMs). We included a subset of cases from a population-base...

journal_title：Environmental health perspectives

authors： Infante-Rivard C,Amre D,Sinnett D

更新日期：2002-06-01 00:00:00

abstract：:Animal studies and small studies in humans have shown that uranium is nephrotoxic. However, more information about its renal effects in humans following chronic exposure through drinking water is required. We measured uranium concentrations in drinking water and urine in 325 persons who had used drilled wells for drin...

journal_title：Environmental health perspectives

authors： Kurttio P,Auvinen A,Salonen L,Saha H,Pekkanen J,Mäkeläinen I,Väisänen SB,Penttilä IM,Komulainen H

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:After Hurricane Katrina, many New Orleans homes remained flooded for weeks, promoting heavy microbial growth. OBJECTIVES:A small demonstration project was conducted November 2005-January 2006 aiming to recommend safe remediation techniques and safe levels of worker protection, and to characterize airborne m...

journal_title：Environmental health perspectives

authors： Chew GL,Wilson J,Rabito FA,Grimsley F,Iqbal S,Reponen T,Muilenberg ML,Thorne PS,Dearborn DG,Morley RL

更新日期：2006-12-01 00:00:00

abstract：:Rats were instilled intrabronchially with 1 mg UICC amosite suspended in 0.2 mL of filtered saline; control animals received the saline instillation only. Five animals from each group were killed on various days after instillation, up to day 128/129. Total retrieved cell counts and differential cell analysis were perf...

journal_title：Environmental health perspectives

authors： Oberdoerster G,Ferin J,Marcello NL,Meinhold SH

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Cancer may be a stem cell (SC)-based disease involving formation of cancer SCs (CSCs) potentially arising from transformation of normal SCs. Cadmium has been linked to human pancreatic cancer. OBJECTIVE:We studied cadmium exposure of human pancreatic ductal epithelial (HPDE) cells and whether SCs may be tar...

journal_title：Environmental health perspectives

authors： Qu W,Tokar EJ,Kim AJ,Bell MW,Waalkes MP

更新日期：2012-09-01 00:00:00

abstract：:Concentrations of polychlorinated biphenyls (PCBs), hydroxylated metabolites of PCBs (HO-PCBs) and octachlorostyrene (4-HO-HpCS), and pentachlorophenol (PCP) were determined in umbilical cord plasma samples from three different regions of Québec. The regions studied included two coastal areas where exposure to PCBs is...

journal_title：Environmental health perspectives

authors： Sandau CD,Ayotte P,Dewailly E,Duffe J,Norstrom RJ

更新日期：2002-04-01 00:00:00

abstract：:Unlike laboratory animals, people are rarely exposed to a single hazardous chemical. However, most of the information documenting adverse human health effects from environmental and occupational contaminants has come from studies focused on exposure to single chemicals, and there is little information available on how...

journal_title：Environmental health perspectives

authors： Carpenter DO,Arcaro KF,Bush B,Niemi WD,Pang S,Vakharia DD

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Few studies have been conducted to identify risk factors for balance and vestibular dysfunction in general populations, but previous studies have reported evidence of adverse effects of lead and cadmium on balance control in high-risk groups. OBJECTIVE:We evaluated the relationship between blood lead and ca...

journal_title：Environmental health perspectives

authors： Min KB,Lee KJ,Park JB,Min JY

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:During May-June 2010, a childhood lead poisoning outbreak related to gold ore processing was confirmed in two villages in Zamfara State, Nigeria. During June-September of that year, villages with suspected or confirmed childhood lead poisoning continued to be identified in Zamfara State. OBJECTIVES:We inves...

journal_title：Environmental health perspectives

authors： Lo YC,Dooyema CA,Neri A,Durant J,Jefferies T,Medina-Marino A,de Ravello L,Thoroughman D,Davis L,Dankoli RS,Samson MY,Ibrahim LM,Okechukwu O,Umar-Tsafe NT,Dama AH,Brown MJ

更新日期：2012-10-01 00:00:00

abstract：:In 1994 officials from the Ohio Department of Health reported that some residents of Lorain County, Ohio, possibly had been exposed to methyl parathion (MP), a highly toxic restricted-use pesticide. The U.S. Centers for Disease Control and Prevention (CDC) assisted in the investigation by providing epidemiologic and l...

journal_title：Environmental health perspectives

authors： Hill RH Jr,Head S,Barr DB,Rubin C,Esteban E,Baker SE,Bailey S,Needham LL

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:The pesticide atrazine does not bind to or activate the classical estrogen receptor (ER), but it up-regulates the aromatase activity in estrogen-sensitive tumor cells. The G protein estrogen receptor (GPR30/GPER) has been reported to be involved in certain biological responses to endogenous estrogens and env...

journal_title：Environmental health perspectives

authors： Albanito L,Lappano R,Madeo A,Chimento A,Prossnitz ER,Cappello AR,Dolce V,Abonante S,Pezzi V,Maggiolini M

更新日期：2015-05-01 00:00:00

abstract：:Inoculation of tumorigenic prostatic stroma and nontumorigenic prostatic epithelia into the subcutaneous space of syngeneic rats induced the development of carcinosarcoma. The induced tumors, which were composed of a mixture of adenocarcinoma and fibrosarcoma, were androgen responsive. This model offers a novel mechan...

journal_title：Environmental health perspectives

authors： Chung LW,Chang SM,Bell C,Zhau H,Ro JY,von Eschenbach AC

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:In male rodents, anogenital distance (AGD) provides a sensitive and continuous correlate of androgen exposure in the intrauterine environment and predicts later reproductive success. Some endocrine-disrupting chemicals can alter male reproductive tract development, including shortening AGD, in both rodents a...

journal_title：Environmental health perspectives

authors： Mendiola J,Stahlhut RW,Jørgensen N,Liu F,Swan SH

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Although previous studies have reported negative associations between exposure to air pollution and cognition, studies of the effects of prenatal and postnatal exposures in early childhood have been limited. OBJECTIVES:We sought to assess the role exposure to fine particulate matter ([Formula: see text]) du...

journal_title：Environmental health perspectives

authors： Rivas I,Basagaña X,Cirach M,López-Vicente M,Suades-González E,Garcia-Esteban R,Álvarez-Pedrerol M,Dadvand P,Sunyer J

更新日期：2019-05-01 00:00:00

abstract：:Collaborative studies were performed to develop a functional assay for fish-killing activity produced by Pfiesteria piscicida. Eight cell lines were used to screen organic fractions and residual water fraction by using a 3-[4, 5-dimethylthiazol-(2-4)]-diphenyltetrazolium bromide cytotoxicity assay. Diethyl ether and a...

journal_title：Environmental health perspectives

authors： Fairey ER,Edmunds JS,Deamer-Melia NJ,Glasgow H Jr,Johnson FM,Moeller PR,Burkholder JM,Ramsdell JS

更新日期：1999-09-01 00:00:00

abstract：:Previous NIOSH studies demonstrated the embryo- and fetotoxicity and teratogenicity of ethylene glycol monoethyl ether (EGEE) applied to the shaved skin of pregnant rats. In the present study ethylene glycol monoethyl ether acetate (EGEEA), ethylene glycol monobutyl ether (EGBE), and diethylene glycol monoethyl ether ...

journal_title：Environmental health perspectives

authors： Hardin BD,Goad PT,Burg JR

更新日期：1984-08-01 00:00:00

abstract：:In August 1997 we performed a follow-up survey of 146 lead-poisoned children from a community near a previously active auto battery recycling smelter in Haina near Santo Domingo, Dominican Republic. Our follow-up survey confirmed a severe incidence of elevated blood lead (BPb) and erythrocyte protoporphyrin/zinc proto...

journal_title：Environmental health perspectives

authors： Kaul B,Sandhu RS,Depratt C,Reyes F

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Methylmercury (MeHg) exposure has been linked to an increased risk of coronary heart disease (CHD). Paraoxonase 1 (PON1), an enzyme located in the high-density-lipoprotein (HDL) fraction of blood lipids, may protect against CHD by metabolizing toxic oxidized lipids associated with low-density liproprotein an...

journal_title：Environmental health perspectives

authors： Ayotte P,Carrier A,Ouellet N,Boiteau V,Abdous B,Sidi EA,Château-Degat ML,Dewailly É

更新日期：2011-08-01 00:00:00

abstract：:Individual variability in human arsenic metabolism has been reported frequently in the literature. This variability could be an underlying determinant of individual susceptibility to arsenic-induced disease in humans. Recent analysis revealing familial aggregation of arsenic metabolic profiles suggests that genetic fa...

journal_title：Environmental health perspectives

authors： Yu L,Kalla K,Guthrie E,Vidrine A,Klimecki WT

更新日期：2003-08-01 00:00:00

abstract：:Hemoglobin adducts of the common metabolite of the tobacco-specific nitrosamine (TSNA) 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB) and of 4-aminobiphenyl (4-ABP) were quantified in blood samples from smokers and nonsmokers to test their suitability for biomonitoring tobacco smoke exposure. Additionally, TSNA adducts were...

journal_title：Environmental health perspectives

authors： Schäffler G,Betz C,Richter E

更新日期：1993-03-01 00:00:00

abstract：:Pesticides used in agriculture may cause adverse health effects among the population living near agricultural areas. However, identifying the populations most likely to be exposed is difficult. We conducted a feasibility study to determine whether satellite imagery could be used to reconstruct historical crop patterns...

journal_title：Environmental health perspectives

authors： Ward MH,Nuckols JR,Weigel SJ,Maxwell SK,Cantor KP,Miller RS

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Animal feeding practices in the United States have changed considerably over the past century. As large-scale, concentrated production methods have become the predominant model for animal husbandry, animal feeds have been modified to include ingredients ranging from rendered animals and animal waste to antibi...

journal_title：Environmental health perspectives

authors： Sapkota AR,Lefferts LY,McKenzie S,Walker P

更新日期：2007-05-01 00:00:00

abstract：:One of the many forms that biological warfare may take is the targeting of major food crops. In a poor country where millions of citizens depend on staple crops such as rice, an act of bioterrorism that destroys the crop would create a famine, resulting not only in malnutrition and starvation but also in reduced immun...

journal_title：Environmental health perspectives

authors： Pellerin C

更新日期：2000-03-01 00:00:00

abstract：:The extracellular lining of the lungs is reviewed. The pulmonary extracellular lining is a complex mixture of phospholipids, proteins and carbohydrates which is absolutely essential for the maintenance of normal pulmonary functions such as gas exchange. Without the lining the lungs would collapse. Alterations in the p...

journal_title：Environmental health perspectives

authors： George G,Hook GE

更新日期：1984-04-01 00:00:00