Abstract:
:This study examined physiological indicants of the neurobiological mediators of negative affect during acute nicotine withdrawal. Eighty subjects (41 male) were assigned to one of four groups (24-h deprived or nondeprived dependent smokers, occasional smokers, and nonsmokers) and participated in an instructed fear conditioning paradigm involving cued administration of electric shock. Negative affective response was measured with fear-potentiated startle during cues that signaled electric shock and during the postcue offset recovery period. Salivary cortisol and self-report measures were also collected. Fear-potentiated startle results indicated that affective recovery postcue offset was delayed in nicotine-deprived women. Nicotine-deprived women also displayed elevated cortisol levels throughout the fear conditioning procedure.
journal_name
Psychophysiologyjournal_title
Psychophysiologyauthors
Hogle JM,Curtin JJdoi
10.1111/j.1469-8986.2006.00406.xsubject
Has Abstractpub_date
2006-07-01 00:00:00pages
344-56issue
4eissn
0048-5772issn
1540-5958pii
PSYP406journal_volume
43pub_type
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