Atrioventricular sequential pacing: differential effect on retrograde conduction related to level of impulse collision.

abstract：BACKGROUND:L-arginine is the precursor of endothelium-derived nitric oxide, an endogenous vasodilator. L-arginine supplementation improves vascular reactivity and functional capacity in peripheral arterial disease (PAD) in small, short-term studies. We aimed to determine the effects of long-term administration of L-arg...

journal_title：Circulation

authors： Wilson AM,Harada R,Nair N,Balasubramanian N,Cooke JP

更新日期：2007-07-10 00:00:00

abstract：BACKGROUND:Coconut oil is high in saturated fat and may, therefore, raise serum cholesterol concentrations, but beneficial effects on other cardiovascular risk factors have also been suggested. Therefore, we conducted a systematic review of the effect of coconut oil consumption on blood lipids and other cardiovascular ...

journal_title：Circulation

authors： Neelakantan N,Seah JYH,van Dam RM

更新日期：2020-03-10 00:00:00

abstract：BACKGROUND:approximately half of patients with heart failure die suddenly as a result of ventricular arrhythmias. Although abnormal Ca(2+) release from the sarcoplasmic reticulum through ryanodine receptors (RyR2) has been linked to arrhythmogenesis, the molecular mechanisms triggering release of arrhythmogenic Ca(2+) ...

journal_title：Circulation

authors： van Oort RJ,McCauley MD,Dixit SS,Pereira L,Yang Y,Respress JL,Wang Q,De Almeida AC,Skapura DG,Anderson ME,Bers DM,Wehrens XH

更新日期：2010-12-21 00:00:00

abstract：BACKGROUND:In humans, angiotensin converting enzyme (ACE) inhibition attenuates the vasoconstriction induced by sympathetic stimulation in a number of peripheral districts. Whether this is also the case in the coronary circulation is unknown, however. METHODS AND RESULTS:In nine normotensive patients with angiographic...

journal_title：Circulation

authors： Perondi R,Saino A,Tio RA,Pomidossi G,Gregorini L,Alessio P,Morganti A,Zanchetti A,Mancia G

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy characterized by right ventricular dysfunction and ventricular arrhythmias. A recent study reported mutations in PKP2, encoding the desmosomal protein plakophilin-2, associated with ARVD/C. The purpose of our st...

journal_title：Circulation

authors： Dalal D,Molin LH,Piccini J,Tichnell C,James C,Bomma C,Prakasa K,Towbin JA,Marcus FI,Spevak PJ,Bluemke DA,Abraham T,Russell SD,Calkins H,Judge DP

更新日期：2006-04-04 00:00:00

abstract：:The National Heart, Lung, and Blood Institute and Office of Rare Diseases at the National Institutes of Health organized a workshop (September 14 to 15, 2006, in Bethesda, Md) to advise on new research directions needed for improved identification and treatment of rare inherited arrhythmias. These included the followi...

journal_title：Circulation

authors： Lehnart SE,Ackerman MJ,Benson DW Jr,Brugada R,Clancy CE,Donahue JK,George AL Jr,Grant AO,Groft SC,January CT,Lathrop DA,Lederer WJ,Makielski JC,Mohler PJ,Moss A,Nerbonne JM,Olson TM,Przywara DA,Towbin JA,Wang LH,M

更新日期：2007-11-13 00:00:00

abstract：BACKGROUND:National and international guidelines recommend fasting lipid panel measurement for risk stratification of patients for prevention of cardiovascular events. However, the prognostic value of fasting versus nonfasting low-density lipoprotein cholesterol (LDL-C) is uncertain. METHODS AND RESULTS:Patients enrol...

journal_title：Circulation

authors： Doran B,Guo Y,Xu J,Weintraub H,Mora S,Maron DJ,Bangalore S

更新日期：2014-08-12 00:00:00

abstract：BACKGROUND:Tetralogy of Fallot is the most common form of congenital heart disease in implantable cardioverter-defibrillator (ICD) recipients, yet little is known about the value of ICDs in this patient population. METHODS AND RESULTS:We conducted a multicenter cohort study in high-risk patients with Tetralogy of Fall...

journal_title：Circulation

authors： Khairy P,Harris L,Landzberg MJ,Viswanathan S,Barlow A,Gatzoulis MA,Fernandes SM,Beauchesne L,Therrien J,Chetaille P,Gordon E,Vonder Muhll I,Cecchin F

更新日期：2008-01-22 00:00:00

abstract：BACKGROUND:Giant cell myocarditis (GCM) typically causes fulminant heart failure, arrhythmias, or heart block, necessitating aggressive immunosuppression, ventricular assist device insertion, or cardiac transplantation. We describe a novel variant of GCM, primarily involving the atria, that displays distinctive clinica...

journal_title：Circulation

authors： Larsen BT,Maleszewski JJ,Edwards WD,Cooper LT Jr,Sobonya RE,Thompson VE,Duckett SG,Peebles CR,Simpson IA,Tazelaar HD

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Although intercellular adhesion molecule-1 (ICAM-1) is known to be expressed in balloon-injured arteries, it remains unknown whether ICAM-1 plays a role in the progression of intimal hyperplasia (IH) induced by balloon injury. METHODS AND RESULTS:We examined the ICAM-1 expression in rat carotid arteries at ...

journal_title：Circulation

authors： Yasukawa H,Imaizumi T,Matsuoka H,Nakashima A,Morimatsu M

更新日期：1997-03-18 00:00:00

abstract：BACKGROUND:Progression of heart failure after initial myocardial injury is mediated in part by various redundant inflammatory mediators, including the widely expressed cyclooxygenase-2 (COX-2). Because COX-2 inhibitors are useful in treating many inflammation-mediated diseases, we asked whether COX-2 inhibition can att...

journal_title：Circulation

authors： Delgado RM 3rd,Nawar MA,Zewail AM,Kar B,Vaughn WK,Wu KK,Aleksic N,Sivasubramanian N,McKay K,Mann DL,Willerson JT

更新日期：2004-03-23 00:00:00

abstract：BACKGROUND:Mitral leaflet extension (MLE) combined with septal myectomy is a new surgical approach to treat hypertrophic obstructive cardiomyopathy (HOCM) and an enlarged mitral leaflet area. The study presents the long-term clinical results and outcome of this technique. METHODS AND RESULTS:MLE entails grafting a glu...

journal_title：Circulation

authors： van der Lee C,Kofflard MJ,van Herwerden LA,Vletter WB,ten Cate FJ

更新日期：2003-10-28 00:00:00

abstract：:The acute hemodynamic effects of captopril were evaluated at cardiac catheterization in 16 children (age, 0.3-18 years) with cardiomyopathy. Twelve children had congestive cardiomyopathy, whereas four had restrictive cardiomyopathy. Hemodynamic measurements were obtained 30 and 60 minutes after the oral administration...

journal_title：Circulation

authors： Bengur AR,Beekman RH,Rocchini AP,Crowley DC,Schork MA,Rosenthal A

更新日期：1991-02-01 00:00:00

abstract：:In this study we extended the characterization of outcome in 1214 medically treated patients with coronary disease by considering nonfatal infarction and death together as ischemic events. At 7 years, the cumulative event rate was 47% (18% for nonfatal infarction as the initial event and 29% for death as the initial e...

journal_title：Circulation

authors： Harris PJ,Lee KL,Harrell FE Jr,Behar VS,Rosati RA

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Glycosphingolipids, integral components of the cell membrane, have been shown to serve as messengers, transducing growth factor-initiated phenotypes. Here, we have examined whether inhibition of glycosphingolipid synthesis could ameliorate atherosclerosis and arterial stiffness in transgenic mice and rabbits...

journal_title：Circulation

authors： Chatterjee S,Bedja D,Mishra S,Amuzie C,Avolio A,Kass DA,Berkowitz D,Renehan M

更新日期：2014-06-10 00:00:00

abstract：BACKGROUND:Paraplegia continues to complicate thoracoabdominal aortic interventions. The elusive mechanism of spinal cord ischemia-reperfusion injury has delayed the development of pharmacological adjuncts. Microglia, the resident macrophages of the central nervous system, can have pathological responses after a variet...

journal_title：Circulation

authors： Bell MT,Puskas F,Agoston VA,Cleveland JC Jr,Freeman KA,Gamboni F,Herson PS,Meng X,Smith PD,Weyant MJ,Fullerton DA,Reece TB

更新日期：2013-09-10 00:00:00

abstract：BACKGROUND:Perioperative management of patients with complete mixing of pulmonary and systemic blood centers on approximately equating pulmonary (Qp) and systemic (Qs) blood flow (Qp/Qs approximately 1). This empirically derived target is opposed by theoretical studies advocating a target Qp/Qs well below 1. We studied...

journal_title：Circulation

authors： Francis DP,Willson K,Thorne SA,Davies LC,Coats AJ

更新日期：1999-11-23 00:00:00

abstract：:Although previous studies in both animals and humans have suggested that cardiac baroreceptors modulate reflex sympathetic vasoconstriction during exercise, more recent studies in conscious animals have not supported this view. To further test this concept in humans, we measured sympathetic nerve discharge with intran...

journal_title：Circulation

authors： Scherrer U,Vissing SF,Victor RG

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Secretoneurin is a neuropeptide located in nerve fibers along blood vessels, is upregulated by hypoxia, and induces angiogenesis. We tested the hypothesis that secretoneurin gene therapy exerts beneficial effects in a rat model of myocardial infarction and evaluated the mechanism of action on coronary endoth...

journal_title：Circulation

authors： Albrecht-Schgoer K,Schgoer W,Holfeld J,Theurl M,Wiedemann D,Steger C,Gupta R,Semsroth S,Fischer-Colbrie R,Beer AG,Stanzl U,Huber E,Misener S,Dejaco D,Kishore R,Pachinger O,Grimm M,Bonaros N,Kirchmair R

更新日期：2012-11-20 00:00:00

abstract：BACKGROUND:It is uncertain whether Helicobacter pylori is associated with ischemic syndromes and whether this association is mediated by the induction of atherosclerosis. In this study, we tested the hypothesis that atherosclerotic stroke shows a selective association with virulent H pylori strains. METHODS AND RESULT...

journal_title：Circulation

authors： Pietroiusti A,Diomedi M,Silvestrini M,Cupini LM,Luzzi I,Gomez-Miguel MJ,Bergamaschi A,Magrini A,Carrabs T,Vellini M,Galante A

更新日期：2002-07-30 00:00:00

abstract：:Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome with an increasingly recognized heterogeneity in pathophysiology. Exercise intolerance is the hallmark of HFpEF and appears to be caused by both cardiac and peripheral abnormalities in the arterial tree and skeletal muscle. Mitochondrial abno...

journal_title：Circulation

authors： Kumar AA,Kelly DP,Chirinos JA

更新日期：2019-03-12 00:00:00

abstract：:The 21-amino acid peptide endothelin-1 (ET-1) is the predominant isoform of the endothelin peptide family, which includes ET-2, ET-3, and ET-4. It exerts various biological effects, including vasoconstriction and the stimulation of cell proliferation in tissues both within and outside of the cardiovascular system. ET-...

journal_title：Circulation

authors： Lüscher TF,Barton M

更新日期：2000-11-07 00:00:00

abstract：:While spatial asynergy at end-systole has been well characterized in patients with coronary artery disease, assessment of regional asynchrony has been hampered by technical constraints. We developed a computer-assisted method for analyzing regional asynchrony from the equilibrium (ECG-gated) radionuclide ventriculogra...

journal_title：Circulation

authors： Holman BL,Wynne J,Idoine J,Neill J

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Coronary heart disease (CHD) is the leading cause of morbidity and mortality in persons with type 2 diabetes mellitus (T2DM). Electron-beam computed tomography (EBCT) detects coronary artery calcium (CAC), a marker of atherosclerotic plaque. Few studies have described EBCT-defined CHD among ethnic minorities...

journal_title：Circulation

authors： Araneta MR,Barrett-Connor E

更新日期：2004-11-02 00:00:00

abstract：BACKGROUND:We surveyed the national experience of coronary artery bypass grafting (CABG) for coronary sequelae of Kawasaki disease (kDa) in 2002. METHODS AND RESULTS:A questionnaire was returned from 323/552 (59%) institutions. Two hundred forty-four patients (188 male 56 female) since 1975 were identified. The mean n...

journal_title：Circulation

authors： Tsuda E,Kitamura S,Cooperative Study Group of Japan.

更新日期：2004-09-14 00:00:00

abstract：BACKGROUND:The impact of misinterpretation of the ECG in patients with acute myocardial infarction (AMI) in the emergency department (ED) setting is not well known. Our goal was to assess the prevalence of the failure to identify high-risk ECG findings in ED patients with AMI and to determine whether this failure is as...

journal_title：Circulation

authors： Masoudi FA,Magid DJ,Vinson DR,Tricomi AJ,Lyons EE,Crounse L,Ho PM,Peterson PN,Rumsfeld JS,Emergency Department Quality in Myocardial Infarction Study Investigators.

更新日期：2006-10-10 00:00:00

abstract：BACKGROUND:Whether reperfusion can cause necrosis of previously viable myocytes (lethal reperfusion injury) remains controversial. Numerous studies examined the ability of various agents to prevent or limit reperfusion injury, but the results were contradictory. In a single-canine-heart model of ischemia-reperfusion, w...

journal_title：Circulation

authors： Zahger D,Yano J,Chaux A,Fishbein MC,Ganz W

更新日期：1995-06-15 00:00:00

abstract：:The relationship between fasting plasma cholesterol and triglyceride concentrations and the frequency and extensiveness of coronary artery disease (CAD) was studied in 496 subjects evaluated for chest pain by coronary arteriography at The Methodist Hospital. One hundred six of the patients had no CAD while 390 had 25%...

journal_title：Circulation

authors： Gotto AM,Gorry GA,Thompson JR,Cole JS,Trost R,Yeshurun D,DeBakey ME

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Few published data describe long-term survival of dialysis patients undergoing surgical versus percutaneous coronary revascularization in the era of drug-eluting stents (DES). METHODS AND RESULTS:Using United States Renal Data System data, we identified 23 033 dialysis patients who underwent coronary revasc...

journal_title：Circulation

authors： Shroff GR,Solid CA,Herzog CA

更新日期：2013-05-07 00:00:00

abstract：BACKGROUND:Microsomal (m) prostaglandin (PG) E₂ synthase (S)-1 catalyzes the formation of PGE₂ from PGH₂, a cyclooxygenase product that is derived from arachidonic acid. Previous studies in mice suggest that targeting mPGES-1 may be less likely to cause hypertension or thrombosis than cyclooxygenase-2-selective inhibit...

journal_title：Circulation

authors： Wang M,Ihida-Stansbury K,Kothapalli D,Tamby MC,Yu Z,Chen L,Grant G,Cheng Y,Lawson JA,Assoian RK,Jones PL,Fitzgerald GA

更新日期：2011-02-15 00:00:00