Relationship between plasma lipid concentrations and coronary artery disease in 496 patients.

abstract：:In a series of 416 women with congenital heart disease seen in the Royal Brompton National Heart and Lung Hospital, London, and the Hospital Giovanni Bosco, Torino, Italy, there were 822 pregnancies. The outcomes of 96 pregnancies in 44 patients with cyanotic congenital heart disease were studied. Patients with the Ei...

journal_title：Circulation

authors： Presbitero P,Somerville J,Stone S,Aruta E,Spiegelhalter D,Rabajoli F

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Anisotropic conduction properties may provide a substrate for reentrant arrhythmias. We investigated the age-dependent changes of structural and functional anisotropy in isolated right atria from infant (1 to 2 months), young (6 to 12 months), and old (6 to 10 years) dogs. METHODS AND RESULTS:The histology ...

journal_title：Circulation

authors： Koura T,Hara M,Takeuchi S,Ota K,Okada Y,Miyoshi S,Watanabe A,Shiraiwa K,Mitamura H,Kodama I,Ogawa S

更新日期：2002-04-30 00:00:00

abstract：BACKGROUND:Few data are available on the long-term outcome of patients who undergo laser-assisted balloon angioplasty for recanalization of occluded peripheral arteries. Because the cost of laser angioplasty is high, the value of the method should be carefully analyzed before it can be considered a routine method for r...

journal_title：Circulation

authors： Geschwind HJ,Aptecar E,Boussignac G,Dubois-Randé JL,Zelinsky R,Poirot G,Tomaru T

更新日期：1991-03-01 00:00:00

abstract：:Activation of the sympathetic nervous system is an important factor in the genesis of ventricular arrhythmias in patients with impaired ventricular function. Such patients have an appropriate substrate that is capable of generating rhythm abnormalities, which may be related to enhanced automaticity, triggered automati...

journal_title：Circulation

authors： Podrid PJ,Fuchs T,Candinas R

更新日期：1990-08-01 00:00:00

abstract：:In a porcine preparation of cardiac arrest, we demonstrated that there is a marked paradox of venous acidemia and arterial alkalemia. This paradox is related to decreased clearance of CO2 from the lungs when pulmonary blood flow is critically reduced. Accordingly, increased venous PCO2 rather than metabolic acidosis d...

journal_title：Circulation

authors： Grundler W,Weil MH,Rackow EC

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:There is uncertainty as to the relative efficacy of coronary artery bypass graft surgery (CABG) in men and women. Differences between sexes may be of greater importance than heretofore because of increased frequency of risk factors for adverse outcome. It is the purpose of this study to examine the changing ...

journal_title：Circulation

authors： Weintraub WS,Wenger NK,Jones EL,Craver JM,Guyton RA

更新日期：1993-11-01 00:00:00

abstract：:Myocardial lactate production indicates anaerobic metabolism resulting from hypoxia or anoxia. Clinically, myocardial lactate extraction of less than 10% has also been used as an indicator of ischemia. Sixteen healthy young male volunteers underwent coronary sinus and aterial catheterization. A coronary sinus pacing c...

journal_title：Circulation

authors： Gertz EW,Wisneski JA,Neese R,Houser A,Korte R,Bristow JD

更新日期：1980-02-01 00:00:00

abstract：:Recent studies have shown that blood flow during closed-chest cardiopulmonary resuscitation (CPR) results primarily from generalized changes in intrathoracic pressure rather than direct compression of the heart. Since ascending aortic and right atrial pressures rise and fall synchronously and to comparable levels duri...

journal_title：Circulation

authors： Ditchey RV,Winkler JV,Rhodes CA

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:We previously reported that administration of elastase inhibitors reverses fatal pulmonary arterial hypertension (PAH) in rats by inducing smooth muscle cell (SMC) apoptosis. We showed in pulmonary artery (PA) organ culture that the mechanism by which elastase inhibitors induce SMC apoptosis involves repress...

journal_title：Circulation

authors： Merklinger SL,Jones PL,Martinez EC,Rabinovitch M

更新日期：2005-07-19 00:00:00

abstract：BACKGROUND:Ventricular tachyarrhythmias are the major clinical manifestation of arrhythmogenic right ventricular disease. Although antiarrhythmic therapy has been widely advocated, there is only limited information available on the efficacy of antiarrhythmic drugs in these patients. METHODS AND RESULTS:The short- and ...

journal_title：Circulation

authors： Wichter T,Borggrefe M,Haverkamp W,Chen X,Breithardt G

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Vascular smooth muscle cell growth factors are postulated to contribute to cardiac allograft vasculopathy (CAV). Few data quantitatively address the timing, location, or stimuli for growth factor expression and relationship to CAV. METHODS AND RESULTS:Acidic fibroblast growth factor (aFGF) mRNA expression w...

journal_title：Circulation

authors： Miller GG,Davis SF,Atkinson JB,Chomsky DB,Pedroso P,Reddy VS,Drinkwater DC,Zhao XM,Pierson RN

更新日期：1999-12-14 00:00:00

abstract：:The purpose of the present study was to evaluate potential diurnal changes in resting coronary blood flow under conditions of comparable myocardial oxygen requirements. We studied 21 conscious, resting dogs instrumented for the measurement of coronary flow, left ventricular pressure, and regional myocardial segment le...

journal_title：Circulation

authors： Fujita M,Franklin D

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:With recognition of disease-causing genes in arrhythmogenic right ventricular cardiomyopathy, mutation analysis is being applied. METHODS AND RESULTS:The role of genotyping in familial assessment for arrhythmogenic right ventricular cardiomyopathy was investigated, including the prevalence of mutations in k...

journal_title：Circulation

authors： Quarta G,Muir A,Pantazis A,Syrris P,Gehmlich K,Garcia-Pavia P,Ward D,Sen-Chowdhry S,Elliott PM,McKenna WJ

更新日期：2011-06-14 00:00:00

abstract：BACKGROUND:To assess the reliability of pediatric echocardiographic measurements, we compared local measurements with those made at a central facility. METHODS AND RESULTS:The comparison was based on the first echocardiographic recording obtained on 735 children of HIV-infected mothers at 10 clinical sites focusing on...

journal_title：Circulation

authors： Lipshultz SE,Easley KA,Orav EJ,Kaplan S,Starc TJ,Bricker JT,Lai WW,Moodie DS,Sopko G,Schluchter MD,Colan SD

更新日期：2001-07-17 00:00:00

abstract：BACKGROUND:Recent transcatheter aortic valve replacement studies have raised concerns about adverse cerebrovascular events. The etiopathology of the embolized material is currently unknown. METHODS AND RESULTS:A total of 40 patients underwent transcatheter aortic valve replacement with the use of a dual filter-based e...

journal_title：Circulation

authors： Van Mieghem NM,Schipper ME,Ladich E,Faqiri E,van der Boon R,Randjgari A,Schultz C,Moelker A,van Geuns RJ,Otsuka F,Serruys PW,Virmani R,de Jaegere PP

更新日期：2013-06-04 00:00:00

abstract：:South Asians (from Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri Lanka) make up one quarter of the world's population and are one of the fastest-growing ethnic groups in the United States. Although native South Asians share genetic and cultural risk factors with South Asians abroad, South Asians in...

journal_title：Circulation

authors： Volgman AS,Palaniappan LS,Aggarwal NT,Gupta M,Khandelwal A,Krishnan AV,Lichtman JH,Mehta LS,Patel HN,Shah KS,Shah SH,Watson KE,American Heart Association Council on Epidemiology and Prevention; Cardiovascular Disease and Stroke i

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:Decreased renal function has been found to be an independent risk factor for cardiovascular outcomes in patients with chronic heart failure (CHF) with markedly reduced left ventricular ejection fraction (LVEF). The aim of this analysis was to evaluate the prognostic importance of renal function in a broader ...

journal_title：Circulation

authors： Hillege HL,Nitsch D,Pfeffer MA,Swedberg K,McMurray JJ,Yusuf S,Granger CB,Michelson EL,Ostergren J,Cornel JH,de Zeeuw D,Pocock S,van Veldhuisen DJ,Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity

更新日期：2006-02-07 00:00:00

abstract：BACKGROUND:Chemokines play an essential role in regulating the infiltration of leukocytes into allografts in experimental models. Little is known of their expression or function after human cardiac transplantation. METHODS AND RESULTS:We analyzed 169 sequential human endomyocardial biopsies by immunocytochemistry for ...

journal_title：Circulation

authors： Melter M,Exeni A,Reinders ME,Fang JC,McMahon G,Ganz P,Hancock WW,Briscoe DM

更新日期：2001-11-20 00:00:00

abstract：:The pathogenesis of paradoxical hypertension after resection of coarctation of the aorta was investigated by comparing the course of seven children undergoing repair of coarctation with five acyanotic children undergoing elective cardiovascular surgery. During the first 24 hours after surgery, all coarctation patients...

journal_title：Circulation

authors： Rocchini AP,Rosenthal A,Barger AC,Castaneda AR,Nadas AS

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Diastolic dysfunction associated with high blood pressure (BP) leads to cardiac remodeling and fibrosis and progression to congestive heart failure. B-type natriuretic peptide (BNP) has BP-lowering, antifibrotic, and antihypertrophic properties, which makes BNP an attractive agent for attenuating the adverse...

journal_title：Circulation

authors： Cataliotti A,Tonne JM,Bellavia D,Martin FL,Oehler EA,Harders GE,Campbell JM,Peng KW,Russell SJ,Malatino LS,Burnett JC Jr,Ikeda Y

更新日期：2011-03-29 00:00:00

abstract：BACKGROUND:Fe2+ released from tissue iron stores may accelerate lipid peroxidation by virtue of its pro-oxidant properties and thus promote early atherogenesis. METHODS AND RESULTS:The present prospective survey addresses the potential association between serum ferritin concentrations and the 5-year progression of car...

journal_title：Circulation

authors： Kiechl S,Willeit J,Egger G,Poewe W,Oberhollenzer F

更新日期：1997-11-18 00:00:00

abstract：BACKGROUND:The role of infections and inflammation in the pathophysiology of coronary heart disease is emerging. We studied the independent and joint effects of these 2 components on coronary risk. METHODS AND RESULTS:We measured baseline levels of C-reactive protein (CRP) and antibodies to adenovirus, enterovirus, cy...

journal_title：Circulation

authors： Roivainen M,Viik-Kajander M,Palosuo T,Toivanen P,Leinonen M,Saikku P,Tenkanen L,Manninen V,Hovi T,Mänttäri M

更新日期：2000-01-25 00:00:00

abstract：:Children with congenital aortic stenosis have "excessive" left ventricular hypertrophy with reduced resting systolic wall stress that allows for supernormal ejection performance. If aortic stenosis is uncorrected, this pattern persists until adulthood. The effect of removing the aortic pressure gradient on left ventri...

journal_title：Circulation

authors： Dorn GW 2nd,Donner R,Assey ME,Spann JF Jr,Wiles HB,Carabello BA

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Catheter ablation of the posteroseptal right atrium has been proposed for control of ventricular rate in patients with tachycardic atrial fibrillation (AF). However, the exact mechanism of rate control is unclear. Because the ablation site corresponds to the location of the slow pathway in patients with AV n...

journal_title：Circulation

authors： Kreiner G,Heinz G,Siostrzonek P,Gössinger HD

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:Thioredoxin 2 (Trx2) is a key mitochondrial protein that regulates cellular redox and survival by suppressing mitochondrial reactive oxygen species generation and by inhibiting apoptosis stress kinase-1 (ASK1)-dependent apoptotic signaling. To date, the role of the mitochondrial Trx2 system in heart failure ...

journal_title：Circulation

authors： Huang Q,Zhou HJ,Zhang H,Huang Y,Hinojosa-Kirschenbaum F,Fan P,Yao L,Belardinelli L,Tellides G,Giordano FJ,Budas GR,Min W

更新日期：2015-03-24 00:00:00

abstract：BACKGROUND:Chagas heart disease is a frequent cause of morbidity and mortality in Latin America. Echocardiography provides useful diagnostic and prognostic information and is an important tool in the management of patients with Chagas disease. METHODS AND RESULTS:A search for relevant publications was obtained from ME...

journal_title：Circulation

authors： Acquatella H

更新日期：2007-03-06 00:00:00

abstract：BACKGROUND:Morbidity and mortality after conventional repair of thoracoabdominal aneurysms remain high. Alternative techniques have been proposed and are the subject of this report. METHODS AND RESULTS:Endovascular grafts that have a means of incorporating the visceral vessels into the aortic repair were divided into ...

journal_title：Circulation

authors： Greenberg RK,Lytle B

更新日期：2008-04-29 00:00:00

abstract：:Aortocoronary vein bypass surgery might not restore normal maximal coronary flow reserve to bypassed coronary vessels because residual diffuse coronary atherosclerosis might limit maximal hyperemia. To investigate the effect of diffuse atherosclerosis and a focal stenosis at the graft-coronary anastomosis, we measured...

journal_title：Circulation

authors： Wilson RF,White CW

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Systemic delivery of bone marrow-derived mesenchymal stem cells (BM-MSCs) is an attractive approach for myocardial repair. We aimed to test this strategy in a rat model after myocardial infarction (MI). METHODS AND RESULTS:BM-MSCs were obtained from rat bone marrow, expanded in vitro to a purity of >50%, an...

journal_title：Circulation

authors： Barbash IM,Chouraqui P,Baron J,Feinberg MS,Etzion S,Tessone A,Miller L,Guetta E,Zipori D,Kedes LH,Kloner RA,Leor J

更新日期：2003-08-19 00:00:00

abstract：:In this study we quantitated the region of preserved myocardium between a subendocardial myocardial infarct (SEMI) and the endocardium in dogs and determined whether this preserved zone was within the region at risk and whether infarct extension could occur in this region. We also evaluated whether a similar subendoca...

journal_title：Circulation

authors： Forman R,Cho S,Factor SM,Kirk ES

更新日期：1983-01-01 00:00:00