Abstract:
:In a porcine preparation of cardiac arrest, we demonstrated that there is a marked paradox of venous acidemia and arterial alkalemia. This paradox is related to decreased clearance of CO2 from the lungs when pulmonary blood flow is critically reduced. Accordingly, increased venous PCO2 rather than metabolic acidosis due to lactic acidosis predominates during the initial 8 min of cardiopulmonary resuscitation. Arterial blood gases fail as indicators of systemic acid-base status and therefore as indicators of tissue acidosis.
journal_name
Circulationjournal_title
Circulationauthors
Grundler W,Weil MH,Rackow ECdoi
10.1161/01.cir.74.5.1071subject
Has Abstractpub_date
1986-11-01 00:00:00pages
1071-4issue
5eissn
0009-7322issn
1524-4539journal_volume
74pub_type
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