Abstract：
:The effects of glucose injection into the hepatic portal vein on neural activity of the lateral hypothalamic area (LHA) were studied in rats. A majority of identified glucose-sensitive neurons in the LHA were inhibited by portal injection of glucose. This was found to be mediated through the alpha-noradrenergic pathways. Most of the glucose-insensitive neurons did not respond to the same procedure. Portal injection of hypertonic saline increased neural activity of some glucose-insensitive neurons but no glucose-sensitive neurons responded. Convergence of hepatic vagal afferent glucose-sensitive units on LHA glucose-sensitive neurons was clarified by this study.
journal_name
Brain Resjournal_title
Brain researchauthors
Shimizu N,Oomura Y,Novin D,Grijalva CV,Cooper PHdoi
10.1016/0006-8993(83)91332-xsubject
Has Abstractpub_date
1983-04-11 00:00:00pages
49-54issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(83)91332-Xjournal_volume
265pub_type
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