Resection of pulmonary metastases from nonseminomatous testicular tumors. Correlation of clinical and histological features with treatment outcome.

abstract：BACKGROUND:Matrix metalloproteinases (MMP) are a gene family of zinc enzymes capable of degrading almost all of the extracellular matrix macromolecules in vivo. Their enzymic activities are believed to be responsible for tumor invasion and metastasis. METHODS:In this study, using peroxidase-antiperoxidase method, mono...

journal_title：Cancer

authors： Shima I,Sasaguri Y,Kusukawa J,Yamana H,Fujita H,Kakegawa T,Morimatsu M

更新日期：1992-12-15 00:00:00

abstract：:Central nervous system (CNS) recurrence continues to be a significant complication in the treatment of adult patients with acute lymphoblastic leukemia (ALL). Preventing CNS recurrence has been a therapeutic challenge and has not been addressed critically in many clinical trials. Adult studies modeled on childhood ALL...

journal_title：Cancer

authors： Jabbour E,Thomas D,Cortes J,Kantarjian HM,O'Brien S

更新日期：2010-05-15 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNA) has been successful in diagnosing epithelial lesions of the breast. Its role in the evaluation of spindle cell and mesenchymal lesions of the breast, which include a variety of benign and malignant conditions, is less clear. This article discusses the cytologic features an...

journal_title：Cancer

authors： Chhieng DC,Cangiarella JF,Waisman J,Fernandez G,Cohen JM

更新日期：1999-12-25 00:00:00

abstract：BACKGROUND:The Tecumseh Community Health Study (TCHS), initiated in 1959 at the University of Michigan School of Public Health, has provided a resource for long term prospective studies of the incidence of cancer in the setting of a midwestern rural farming community. METHODS:A survey of total and site specific cancer...

journal_title：Cancer

authors： Waterhouse D,Carman WJ,Schottenfeld D,Gridley G,McLean S

更新日期：1996-02-15 00:00:00

abstract：BACKGROUND:American Indians/Alaskan Natives (AI/ANs) have the worst 5-year cancer survival of all racial/ethnic groups in the United States. Causes for this disparity are unknown. The authors of this report examined the receipt of cancer treatment among AI/AN patients compared with white patients. METHODS:This was a r...

journal_title：Cancer

authors： Javid SH,Varghese TK,Morris AM,Porter MP,He H,Buchwald D,Flum DR,Collaborative to Improve Native Cancer Outcomes (CINCO).

更新日期：2014-07-15 00:00:00

abstract：:A clinicopathologic study of 79 patients with parosteal osteogenic sarcoma revealed that more females than males were affected and that most of the patients were in the second to the fourth decades of life. Sixty-eight percent of the patients had involvement of the posterior aspect of the lower femoral shaft. The roen...

journal_title：Cancer

authors： Unni KK,Dahlin DC,Beabout JW,Ivins JC

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:The National Quality Forum endorses the recommendation of examining at least 12 lymph nodes (LNs) from colorectal cancer (CRC) specimens. However, heterogeneity in LN harvest exists. The objective of this study was to investigate the clinicopathologic factors that influence LN yield. METHODS:The authors use...

journal_title：Cancer

authors： Chou JF,Row D,Gonen M,Liu YH,Schrag D,Weiser MR

更新日期：2010-06-01 00:00:00

abstract：:Since 1969, 29 previously untreated patients with Stage III nodular malignant lymphoreticular (MLT) have received total central lymphatic (TCL) irradiation. The volume irradiated included the entire abdomen, Waldeyer's ring, and preauricular nodes in addition to the usual regions encompassed by total nodal irradiation...

journal_title：Cancer

authors： Cox JD,Komaki R,Kun LE,Wilson JF,Greenberg M

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:The authors previously demonstrated that never-smokers with stage IIIB/IV nonsmall cell lung cancer (NSCLC) lived 50% longer than former/current smokers. This observation persisted after adjusting for age, performance status, and sex. In this study, the authors hypothesized that smoking-dependent differences...

journal_title：Cancer

authors： Paik PK,Johnson ML,D'Angelo SP,Sima CS,Ang D,Dogan S,Miller VA,Ladanyi M,Kris MG,Riely GJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The behavior of diffuse peritoneal mesotheliomas in women and the possible relation between tumor morphology and outcome are uncertain. Reported survival has ranged from < 1 month to > 14 years, and a previous study found that tumor morphology could not be used reliably for predicting outcome. The authors ex...

journal_title：Cancer

authors： Kerrigan SA,Turnnir RT,Clement PB,Young RH,Churg A

更新日期：2002-01-15 00:00:00

abstract：BACKGROUND:Polyunsaturated n-3 fatty acids have been shown to inhibit the growth and metastasis of tumors. This double-blind, randomized study was designed to evaluate the hypothesis that polyunsaturated n-3 fatty acids can improve metabolic parameters, decrease chemical indices of inflammation, enhance quality of life...

journal_title：Cancer

authors： Ogilvie GK,Fettman MJ,Mallinckrodt CH,Walton JA,Hansen RA,Davenport DJ,Gross KL,Richardson KL,Rogers Q,Hand MS

更新日期：2000-04-15 00:00:00

abstract：BACKGROUND:Treatment with traditional cytotoxic chemotherapy regimens containing streptozocin or dacarbazine has resulted in only marginal benefit for patients with metastatic neuroendocrine tumors. The use of these regimens has been further limited by their potential toxicity. Gemcitabine is generally well tolerated a...

journal_title：Cancer

authors： Kulke MH,Kim H,Clark JW,Enzinger PC,Lynch TJ,Morgan JA,Vincitore M,Michelini A,Fuchs CS

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Patients with advanced soft tissue sarcomas (STS) have limited therapeutic options. Sorafenib (BAY 43-9006) is a multitargeted tyrosine kinase inhibitor of raf, vascular endothelial growth factor receptors 1 (VEGFR1) through 3, platelet-derived growth factor B, fms-like tyrosine kinase 3, and c-kit, and some...

journal_title：Cancer

authors： von Mehren M,Rankin C,Goldblum JR,Demetri GD,Bramwell V,Ryan CW,Borden E

更新日期：2012-02-01 00:00:00

abstract：:International comparisons have provided striking correlations between fat consumption and risk of breast cancer, but these comparisons do not often consider variations in life style. Case-control studies carried out in several countries showed no real association between fat intake and breast cancer. There is some evi...

journal_title：Cancer

authors： Kritchevsky D

更新日期：1990-09-15 00:00:00

abstract：BACKGROUND:Aggressive treatment of early stage prostate carcinoma (PC) is limited primarily to two modalities: radical prostatectomy (RP) and external beam radiation therapy (RT). The authors conducted a population-based study of Detroit area men with localized PC to determine the outcome of bowel, urinary, and sexual ...

journal_title：Cancer

authors： Schwartz K,Bunner S,Bearer R,Severson RK

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Patients with hereditary leiomyomatosis and renal cell carcinoma (HLRCC) resulting from fumarate hydratase (FH) mutations may present with skin, uterine, and renal tumors, with each having unique pathologic features. This study investigated the association between prospectively identified suspicious patholog...

journal_title：Cancer

authors： Kopp RP,Stratton KL,Glogowski E,Schrader KA,Rau-Murthy R,Russo P,Coleman JA,Offit K

更新日期：2017-07-01 00:00:00

abstract：:A routine admission chest radiograph (CXR) in pediatric patients with cancer who are admitted to the hospital for fever and neutropenia has been advised because the signs and symptoms of pneumonia may be absent. The authors studied 131 consecutive patient admissions for fever and neutropenia to evaluate the diagnostic...

journal_title：Cancer

authors： Katz JA,Bash R,Rollins N,Cash J,Buchanan GR

更新日期：1991-09-01 00:00:00

abstract：:Fifteen selected patients with advanced intrathoracic non-small cell lung cancer and solitary metastasis were treated by a combined program including craniotomy, brain and chest irradiation, and systemic chemotherapy. One patient died because of cerebral hemorrhage after the operation. Five patients failed to achieve ...

journal_title：Cancer

authors： Tummarello D,Porfiri E,Rychlicki F,Miseria S,Cellerino R

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Karyotypic abnormalities in sporadic Burkitt lymphoma (BL) have been described extensively. However, to the authors' knowledge, very limited studies have focused on the secondary chromosomal abnormalities in pediatric BL as compared with those of adult BL and on their prognostic impact. METHODS:A retrospect...

journal_title：Cancer

authors： Onciu M,Schlette E,Zhou Y,Raimondi SC,Giles FJ,Kantarjian HM,Medeiros LJ,Ribeiro RC,Pui CH,Sandlund JT

更新日期：2006-09-01 00:00:00

abstract：:The glucocorticoid receptor (GR) quantitation by a whole-cell assay and/or cytosol technique and the in vitro sensitivity to steroids have been assessed in peripheral blood cells from normal donors and patients with chronic lymphatic leukemia (CLL), acute lymphoblastic leukemia (ALL), lymphosarcoma cell leukemia (LSCL...

journal_title：Cancer

authors： Nanni P,Nicoletti G,Prodi G,Galli MC,De Giovanni C,Grilli S,Lollini PL,Gobbi M,Cavo M,Tura S

更新日期：1982-02-15 00:00:00

abstract：BACKGROUND:Ethnic disparities in colorectal cancer (CRC) mortality are observed in the United States. The authors studied this among minority New Yorkers with CRC. METHODS:In a study of CRC patients in a New York City teaching hospital, 5-year data on demographics and clinical features were reviewed. Adjusted cancer-r...

journal_title：Cancer

authors： Kanna B,Narang TK,Atwal T,Paul D,Azeez S

更新日期：2009-12-01 00:00:00

abstract：:Utah cancer mortality for the years 1950-1969 and morbidity for the years 1966-1970 are reported. Utah had 18% fewer cases of cancer than expected based on the Third National Cancer Survey, and 24% fewer cancer deaths than expected based on national mortality data. Cancer sites associated with cigarette smoking and al...

journal_title：Cancer

authors： Lyon JL,Gardner JW,Klauber MR,Smart CR

更新日期：1977-06-01 00:00:00

abstract：:Lymphoid cells from two patients with hand-mirror variant of acute lymphoblastic leukemia (ALL) were studied with various monoclonal antibodies in attempts to determine their derivation and differentiation. The predominant feature of the malignant bone marrow cells was strong reactivity with antibody 3A1, which stains...

journal_title：Cancer

authors： Gramatzki M,Strong DM,Duval-Arnould B,Morstyn G,Schumacher HR

更新日期：1985-01-01 00:00:00

abstract：:Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily. Usual side effects were mild sedation and dry mouth, but three patients found it ...

journal_title：Cancer

authors： Moertel CG,Kvols LK,Rubin J

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Treatment outcomes were analyzed for retromolar trigone squamous cell carcinoma. METHODS:Between June 1966 and August 2003, 99 patients were treated with radiotherapy alone (35 patients) or radiotherapy combined with surgery (64 patients). Followup ranged from 0.2 to 23.8 years (median, 3.3 yrs). All living...

journal_title：Cancer

authors： Mendenhall WM,Morris CG,Amdur RJ,Werning JW,Villaret DB

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Metallothioneins (MT) are endogenous metalloproteins involved in the homeostasis of essential metals and detoxification of toxic metals. Some recent experimental studies suggested tumor resistance to cisdiamminedichloroplatin may be associated with overexpression of MT in the tumor. METHODS:The presence of ...

journal_title：Cancer

authors： Chin JL,Banerjee D,Kadhim SA,Kontozoglou TE,Chauvin PJ,Cherian MG

更新日期：1993-11-15 00:00:00

abstract：BACKGROUND:Many case reports describing various benign and malignant disease entities diagnosed in cystic parotid gland lesions by fine-needle aspiration (FNA) exist in the literature. Very few studies, however, discuss the efficacy and the diagnostic difficulties of FNA cytology in such lesions. The authors report a 5...

journal_title：Cancer

authors： Nasuti JF,Yu GH,Gupta PK

更新日期：2000-04-25 00:00:00

abstract：BACKGROUND:Some studies have suggested that the use of calcium channel blockers may increase the risk of cancer. A possible association of the use of calcium channel blockers with cancer incidence and cancer mortality was addressed using data from the Nurses' Health Study. METHODS:In this study, a total of 18,635 fema...

journal_title：Cancer

authors： Michels KB,Rosner BA,Walker AM,Stampfer MJ,Manson JE,Colditz GA,Hennekens CH,Willett WC

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Many patients with stage III colon adenocarcinoma do not receive adjuvant chemotherapy despite the proven survival advantage it offers. To enhance the provision of optimal cancer care, patient characteristics associated with not receiving guideline-adherent treatment must be identified among patients with op...

journal_title：Cancer

authors： Winget M,Hossain S,Yasui Y,Scarfe A

更新日期：2010-10-15 00:00:00

abstract：BACKGROUND:Nonionizing radiation, such as radiofrequency field and near infrared laser, induces thermal cytotoxicity in cancer cells treated with gold nanoparticles. Quantum dots are fluorescent semiconducting nanoparticles that were hypothesized to induce similar injury after radiofrequency field irradiation. METHODS...

journal_title：Cancer

authors： Glazer ES,Curley SA

更新日期：2010-07-01 00:00:00