Non-small cell lung cancer. Neuroresection of the solitary intracranial metastasis followed by radiochemotherapy.

abstract：:Deguelin is a rotenoid compound that exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants. An analysis of evidence from both in vitro and in vivo studies suggests that deguelin displays potent anticancer activity against multiple cancer types and exhibits chemopreventive pot...

journal_title：Cancer

authors： Varughese RS,Lam WS,Marican AABH,Viganeshwari SH,Bhave AS,Syn NL,Wang J,Wong AL,Kumar AP,Lobie PE,Lee SC,Sethi G,Goh BC,Wang L

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:A somatic gain-of-function mutation of the Janus kinase 2 (JAK2) gene has been identified in chronic myeloproliferative disorders, which appear to have a sporadic occurrence in most individuals. The authors studied the biologic significance of the JAK2 (V617F) mutation in familial myeloproliferative disorder...

journal_title：Cancer

authors： Rumi E,Passamonti F,Pietra D,Della Porta MG,Arcaini L,Boggi S,Elena C,Boveri E,Pascutto C,Lazzarino M,Cazzola M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Methotrexate is readily absorbed from the intestinal tract. When given to patients with urinary diversion to the intestinal tract, methotrexate may be reabsorbed into the circulation, thus increasing its serum concentration and potentially increasing its toxicity. METHODS:Forty-eight patients with transitio...

journal_title：Cancer

authors： Srinivas S,Mahalati K,Freiha FS

更新日期：1998-03-15 00:00:00

abstract：BACKGROUND:National and international bodies acknowledge the benefit of exercise for people with cancer, yet limited accessibility to related programing remains. Given their involvement in managing the disease, cancer centers can play a central role in delivering exercise-oncology services. The authors developed and im...

journal_title：Cancer

authors： Santa Mina D,Au D,Auger LE,Alibhai SMH,Matthew AG,Sabiston CM,Oh P,Ritvo PG,Chang EB,Jones JM

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Hypercalcemia has rarely been reported in patients with Richter's syndrome (RS). In this article, the authors report four cases with complementary pathophysiologic examinations. METHODS:Four patients with hypercalcemia that indicated RS were admitted to the study unit between 1980 and 1994 with the followin...

journal_title：Cancer

authors： Beaudreuil J,Lortholary O,Martin A,Feuillard J,Guillevin L,Lortholary P,Raphael M,Casassus P

更新日期：1997-03-15 00:00:00

abstract：:To collect an unselected total bronchial carcinoma population as a basis for randomized therapy studies during 1971-1976, 537 patients with suspected bronchial carcinoma were investigated. Of these, 109 were found to have an adenocarcinoma in the lung. Of the 109, 10 had been initially diagnosed as not having adenocar...

journal_title：Cancer

authors： Nõu E

更新日期：1981-11-01 00:00:00

abstract：:A case of sinus histiocytosis with massive lymphadenopathy (SHML) in which cranial nerve function was impaired is described. Severe paraparesis due to an epidural block at the C2 and C5-T2 levels was also present. Treatment with cytotoxic agents resulted in a dramatic decrease in the size of the involved lymph nodes a...

journal_title：Cancer

authors： Haas RJ,Helmig MS,Prechtel K

更新日期：1978-07-01 00:00:00

abstract：:The American Joint Committee on Cancer proposes the following criteria for evaluating putative prognostic factors: they must be (1) significant, (2) independent, and (3) clinically important. Furthermore, we suggest the criteria for selecting a prognostic system that includes TNM and new prognostic factors. These crit...

journal_title：Cancer

authors： Burke HB,Henson DE

更新日期：1993-11-15 00:00:00

abstract：BACKGROUND:Epidermal growth factor (EGF) and EGF-regulated processes play an important role in steroid signal transduction. Comparative analysis of EGF and steroid receptor expression and the sensitivity of early stages of proliferation induction, such as activation of phospholipid turnover to EGF and steroids, may pro...

journal_title：Cancer

authors： Gershtein ES,Shatskaya VA,Kostyleva OI,Ermilova VD,Kushlinsky NE,Krasil'nikov MA

更新日期：1995-12-15 00:00:00

abstract：:Doubling times were estimated for 15 breast carcinomas in 13 patients, and were found to be between 42 and 397 days with the average at 211 days. The mean lead time at mean growth rate from the average size of 44 preclinical to the average size of 118 clinical tumors was estimated to be 3 years. This period may be con...

journal_title：Cancer

authors： Lundgren B

更新日期：1977-10-01 00:00:00

abstract：:Renal cell carcinoma is the most common renal neoplasm associated with pregnancy. The most common presenting symptoms are pain and a palpable mass. Although renal neoplasms in pregnancy are rare, the pregnancy demands special consideration in the methods of diagnostic evaluation. The relationship between renal cell ca...

journal_title：Cancer

authors： Walker JL,Knight EL

更新日期：1986-11-15 00:00:00

abstract：BACKGROUND:Both genetic and epigenetic changes in nonsmall cell lung cancer (NSCLC) are known to be a common event. METHODS:Mutations in the epidermal growth factor receptor gene (EGFR), HER-2, and KRAS and the methylation profile of 9 genes for NSCLC were analyzed and correlated with clinical and histologic data. RE...

journal_title：Cancer

authors： Suzuki M,Shigematsu H,Iizasa T,Hiroshima K,Nakatani Y,Minna JD,Gazdar AF,Fujisawa T

更新日期：2006-05-15 00:00:00

abstract：:Fatigue has been described as the most common, most debilitating side effect of cancer treatment and is frequently reported as a long-term complication of treatment as well. Despite the prevalence of fatigue and its profoundly negative effect on patients' quality of life, little is known about the specific mechanisms ...

journal_title：Cancer

authors： Mock V

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:In light of the steadily improving capability to treat opportunistic infections, the authors reviewed their recent experience with short course empiric radiotherapy for the treatment of human immunodeficiency virus (HIV)-associated presumed central nervous system (CNS) lymphoma. METHODS:Medical records were...

journal_title：Cancer

authors： Donahue BR,Sullivan JW,Cooper JS

更新日期：1995-07-15 00:00:00

abstract：BACKGROUND:Patients with human papillomavirus (HPV)-related oropharyngeal cancer (OPC) have improved survival when compared with those with HPV-negative OPC. Unfortunately, the American Joint Committee on Cancer seventh edition (AJCC-7ed) staging system does not account for the prognostic advantage observed with HPV-po...

journal_title：Cancer

authors： Malm IJ,Fan CJ,Yin LX,Li DX,Koch WM,Gourin CG,Pitman KT,Richmon JD,Westra WH,Kang H,Quon H,Eisele DW,Fakhry C

更新日期：2017-05-15 00:00:00

abstract：:The validity of current staging systems for malignant melanoma was analyzed in a prospective study on 220 patients with extremity melanoma. Patients were followed 2 to 9 years after a wide excision of the primary, regional cytostatic perfusion and dissection of regional lymph nodes. The "original three-stage" system y...

journal_title：Cancer

authors： Ghussen F,Krüger I,Groth W

更新日期：1990-07-15 00:00:00

abstract：:The combination of conservation surgery and radiation therapy for early breast cancer is gaining acceptance as an alternative to radical mastectomy. This article reviews the results of randomized trials showing that there is no advantage to a radical mastectomy in patients with early breast cancer. In addition, the ar...

journal_title：Cancer

authors： Montague ED,Ames FC,Schell SR,Romsdahl MM

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:This qualitative study investigated the medical decision-making preferences of adolescent oncology patients and the parental and clinician behaviors that adolescents report to be supportive of their preferred level of decision-making involvement. METHODS:Interviews were conducted with 40 adolescents between...

journal_title：Cancer

authors： Weaver MS,Baker JN,Gattuso JS,Gibson DV,Sykes AD,Hinds PS

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Five-year survival rates after resection of liver metastases from colorectal carcinoma are close to 25%. Recurrences occur in two-thirds of the patients after surgery. Selection of patients likely to benefit from surgery remains controversial and subjective. METHODS:Data from 1568 patients with resected liv...

journal_title：Cancer

authors： Nordlinger B,Guiguet M,Vaillant JC,Balladur P,Boudjema K,Bachellier P,Jaeck D

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The role of the interaction between tumor cells and inflammatory cells in nonsmall cell lung carcinoma (NSCLC) is unclear. In this study, the authors assessed the prognostic impact of intratumoral cluster of differentiation 66b (carcinoembryonic antigen-related cell adhesion molecule 8 [CD66b])-positive neut...

journal_title：Cancer

authors： Ilie M,Hofman V,Ortholan C,Bonnetaud C,Coëlle C,Mouroux J,Hofman P

更新日期：2012-03-15 00:00:00

abstract：:Because Forssman antigen, one of the most well-known heteroantigens, has been noted in certain cancerous tissues, it would seem that the serum levels of the Forssman antibody of patients with these cancers would be low, owing to the absorption of the naturally occurring antibody by the Forssman antigen-containing canc...

journal_title：Cancer

authors： Hirayama R,Hirokawa K,Takagi Y,Utsuyama M,Maejima S,Takemura K,Mishima Y,Makinodan T

更新日期：1989-04-15 00:00:00

abstract：BACKGROUND:Disruption of the lymphatic circulation through breast carcinoma-associated axillary lymph node dissection, with or without radiation therapy, reportedly is the most common cause of lymphedema in developed countries. There is no cure for breast carcinoma-associated lymphedema. Although intermittent pneumatic...

journal_title：Cancer

authors： Szuba A,Achalu R,Rockson SG

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Achieving a pathologic complete response (pCR) with neoadjuvant chemotherapy (NAC) in patients with muscle-invasive bladder cancer (MIBC) has been associated with improved overall survival (OS). This study was aimed at evaluating the impact of pathologic downstaging (pDS; ie, a pT stage at least 1 stage lowe...

journal_title：Cancer

authors： Martini A,Jia R,Ferket BS,Waingankar N,Plimack ER,Crabb SJ,Harshman LC,Yu EY,Powles T,Rosenberg JE,Pal SK,Vaishampayan UN,Necchi A,Wiklund NP,Mehrazin R,Mazumdar M,Sfakianos JP,Galsky MD

更新日期：2019-09-15 00:00:00

abstract：BACKGROUND:Acquired Glanzmann's thrombasthenia is a rare hemorrhagic diathesis resulting from impaired adhesive function of the platelet receptor GPIIb/IIIa (alpha(IIb)beta3). Typically, this disorder develops during adulthood, with patients manifesting fluctuating clinical and laboratory findings. To date, the underly...

journal_title：Cancer

authors： Malik U,Dutcher JP,Oleksowicz L

更新日期：1998-05-01 00:00:00

abstract：:Flow cytometric measurements were done on 51 ovarian carcinoma specimens collected from consecutive patients in a prospective study. The ploidy status was related to the course of the disease. The tumors from 26 (52%) of 50 evaluable patients had DNA aneuploidy. Patients with diploid tumors were more often considered ...

journal_title：Cancer

authors： Iversen OE

更新日期：1988-03-01 00:00:00

abstract：:The frequency and significance of hyperprolactinemia was studied in 21 consecutive, untreated male patients with bronchogenic carcinoma. Seven patients (33%) were found to have elevated serum prolactin (hPRL) levels. No correlation was demonstrated between increased hPRL levels, tissue histology, or tumor burden. L-do...

journal_title：Cancer

authors： Davis S,Proper S,May PB,Ertel NH

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Assessment of the responses of osteosarcoma patients to preoperative chemotherapy is of clinical importance. The purpose of this study was to estimate the accuracy of angiography and thallium-201 scintigraphy, compared with histology, in assessing the responses of patients with osteosarcoma to preoperative c...

journal_title：Cancer

authors： Kunisada T,Ozaki T,Kawai A,Sugihara S,Taguchi K,Inoue H

更新日期：1999-09-15 00:00:00

abstract：BACKGROUND:The antitumor activity of the chemical conjugate and recombinant forms of the mitotoxin basic fibroblast growth factor (bFGF) saporin (SAP) and the bFGF receptor-directed immunotoxin 11A8-SAP against human ovarian teratocarcinoma PA-1 was examined in athymic nude mice. Alternative administration schedules to...

journal_title：Cancer

authors： Davol P,Beitz JG,Mohler M,Ying W,Cook J,Lappi DA,Frackelton AR Jr

更新日期：1995-07-01 00:00:00

abstract：:A case of osteosarcoma arising in the soft tissue of the larynx in an elderly man is presented with light and electron microscopic documentation. The patient developed chronic hoarseness and a recurring polypoid laryngeal tumor, causing acute airway obstruction. He was treated by total laryngectomy, but he died with m...

journal_title：Cancer

authors： Dahm LJ,Schaefer SD,Carder HM,Vellios F

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:The differential diagnosis of severe acute respiratory syndrome (SARS) in patients with cancer can be challenging. Although diagnostic criteria for SARS have been issued by the World Health Organization (WHO), simple adoption of the established criteria may lead to overdiagnosis in patients with cancer or to...

journal_title：Cancer

authors： Gu J,Wu A,Li J,Zhang X,Fang J,Li M,Yao Y,Ke Y,Gu J,Chen M,You W

更新日期：2004-04-01 00:00:00