Abstract:
:Most gliomas in neurofibromatosis type 1 (NF1) are pilocytic astrocytomas (PAs) of the optic pathway occurring in young children. However, some individuals develop gliomas that lack the typical NF1-associated clinical features or radiographic appearance. We identified 17 atypical presentations from a review of 100 patients with NF1-associated gliomas. Biopsy showed that 9 were not classic PAs. These data highlight the value of biopsy in NF1-associated gliomas with unusual clinical or radiographic presentations.
journal_name
Neurologyjournal_title
Neurologyauthors
Leonard JR,Perry A,Rubin JB,King AA,Chicoine MR,Gutmann DHdoi
10.1212/01.wnl.0000240076.31298.47subject
Has Abstractpub_date
2006-10-24 00:00:00pages
1509-12issue
8eissn
0028-3878issn
1526-632Xpii
67/8/1509journal_volume
67pub_type
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