1-Deamino-8-D-arginine vasopressin as a therapy for the bleeding diathesis of renal failure.

abstract：BACKGROUND:End-stage renal disease (ESRD) is a disease with an aging population and a high prevalence of cognitive impairment affecting quality of life, health care costs and mortality. Structural changes in the brain with decreased white matter integrity have been observed in ESRD. Understanding the changes in cogniti...

journal_title：American journal of nephrology

authors： Gupta A,Lepping RJ,Yu AS,Perea RD,Honea RA,Johnson DK,Brooks WM,Burns JM

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although the effect of exercise on health is well established, nephrologists seldom consider physical activity in the treatment of chronic kidney disease (CKD) or CKD in the presence of diabetes mellitus (DM/CKD). The aim of the present study was to analyze the benefits of leisure-time physical activity...

journal_title：American journal of nephrology

authors： Wang IK,Tsai MK,Liang CC,Yen TH,Huang CC,Wen SF,Wen CP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:The mesothelium of patients undergoing peritoneal dialysis (PD) is exposed to glucose in dialysate. Glucose metabolites 3-deoxyglucosone and advanced glycation endproducts (AGEs) in the PD fluid induce peritoneal damage. Circulating factors also affect the peritoneum in the uremic model and predialysis ...

journal_title：American journal of nephrology

authors： Hasuike Y,Moriguchi R,Hata R,Miyagawa K,Kuragano T,Aizawa M,Yamamoto S,Yanase K,Izumi M,Tanimoto T,Nakanishi T

更新日期：2007-01-01 00:00:00

abstract：:The number of patients with end-stage renal disease undergoing kidney transplantation - both cadaveric and living-donor - continues to rise. With long-term graft survival relatively fixed, this trend means that increasing numbers of patients are returning to dialysis after graft loss. Most will never be retransplanted...

journal_title：American journal of nephrology

authors： Fuquay R,Teitelbaum I

更新日期：2012-01-01 00:00:00

abstract：AIMS:Although there are plenty of data about the differences in left ventricular tissue Doppler (TD) velocities by preload reduction, only a few studies regarding right ventricular function are found in the literature. We investigated the effect of intravascular volume reduction on right ventricular function by ultrafi...

journal_title：American journal of nephrology

authors： Arinc H,Gunduz H,Tamer A,Ozhan H,Akdemir R,Saglam H,Oguzhan A,Uyan C

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND/AIMS:The value of neutrophil-gelatinase-associated lipocalin (NGAL), a novel biomarker in the detection of acute renal failure in children after cardiac surgery, has been highlighted in previous studies. The incidence of percutaneous coronary intervention (PCI) increases, which may possibly result in increas...

journal_title：American journal of nephrology

authors： Bachorzewska-Gajewska H,Malyszko J,Sitniewska E,Malyszko JS,Dobrzycki S

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:Vitamin D insufficiency drives secondary hyperparathyroidism (SHPT) and is associated with increased cardiovascular mortality in patients with chronic kidney disease (CKD). SHPT is poorly addressed by current vitamin D repletion options. The present study evaluated a novel investigational vitamin D repl...

journal_title：American journal of nephrology

authors： Sprague SM,Silva AL,Al-Saghir F,Damle R,Tabash SP,Petkovich M,Messner EJ,White JA,Melnick JZ,Bishop CW

更新日期：2014-01-01 00:00:00

abstract：:Renal disease is a common complication in malaria infection. In acute falciparum malaria renal involvement is usually mild, but in severe disease acute renal failure is a major problem. Acute renal failure has been attributed to ischaemic tubular necrosis from hypovolaemia resulting from vasodilatation due to endothel...

journal_title：American journal of nephrology

authors： Sinniah R,Lye W

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND/AIMS:We examined the correlations between renal biopsy findings in Wegener's granulomatosis and renal function at baseline and 1 year in 22 patients who presented between 1988 and 1999. METHODS:Renal histology was independently reviewed by 2 pathologists who were masked to the clinical data. The primary out...

journal_title：American journal of nephrology

authors： Haroun MK,Stone JH,Nair R,Racusen L,Hellmann DB,Eustace JA

更新日期：2002-09-01 00:00:00

abstract：:Chronic kidney disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importan...

journal_title：American journal of nephrology

authors： Piccoli GB,Alrukhaimi M,Liu ZH,Zakharova E,Levin A,World Kidney Day Steering Committee.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cisplatin (CIS) induces nephrotoxicity partly through renal vasoconstriction and decreased glomerular filtration effects thought to involve adenosine acting on adenosine A(1) receptors (A1Rs). We studied the effect of the orally active, A1R antagonist tonapofylline (BG9928) on biochemical measures of re...

journal_title：American journal of nephrology

authors： Gill A,Wortham K,Costa D,Davis W,Ticho B,Whalley E

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The value of chronic kidney disease (CKD) screening in the general population remains unclear but may be beneficial in populations with high disease prevalence. We examined risk factors for albuminuria among participants in a state-wide CKD screening program in Hawaii. METHODS:The National Kidney Foundation...

journal_title：American journal of nephrology

authors： Wong LL,Kalantar-Zadeh K,Page V,Hayashida G,You AS,Rhee CM

更新日期：2017-01-01 00:00:00

abstract：:A 22-year-old woman presented glomerulonephritis with Schönlein-Henoch-like syndrome and monoclonal abnormality. One month later, she developed a rapidly progressive glomerulonephritis with hypertension and persistent purpura. In the two renal biopsies performed during the first and the second attack, mesangial expans...

journal_title：American journal of nephrology

authors： Orfila C,Meeus F,Bernadet P,Lepert JC,Suc JM

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Tacrolimus has been reported to be effective in refractory nephrotic syndrome, such as focal segmental glomerulosclerosis and membranous nephropathy. Some IgA nephropathy (IgAN) patients with massive proteinuria showed resistance to steroids and/or cytotoxic immunosuppressants based on the supportive therapy...

journal_title：American journal of nephrology

authors： Zhang Q,Shi SF,Zhu L,Lv JC,Liu LJ,Chen YQ,Zhang H,Wang HY

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is highly prevalent among patients on hemodialysis (HD) and is associated with poor prognosis. Treatment with interferon and ribavirin is poorly tolerated, and few data are available on the impact of new direct-acting antivirals (DAAs). This study was intended to analyze the...

journal_title：American journal of nephrology

authors： Abad S,Vega A,Hernández E,Mérida E,de Sequera P,Albalate M,Macías N,Milla M,López-Gómez JM

更新日期：2017-01-01 00:00:00

abstract：:This study was designed to evaluate beta-adrenergic responsiveness as assessed by the generation of cyclic AMP after the subcutaneous administration of epinephrine in 31 subjects: normal controls, patients with chronic renal insufficiency, hemodynamically stable patients on chronic acetate dialysis and hemodynamically...

journal_title：American journal of nephrology

authors： Fuiano G,Dal Canton A,Maj M,Testa A,Memoli B,Conte G,Ariano MG,Guarriello L,Russo D,Andreucci VE

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:More than 50% of American adolescents and adults report having used illicit drugs in their lifetime. We examined the association of lifetime opiate and cocaine use with reduced kidney function, albuminuria and rapid kidney function decline among urban-dwelling adults. METHODS:Our prospective cohort included...

journal_title：American journal of nephrology

authors： Novick T,Liu Y,Alvanzo A,Zonderman AB,Evans MK,Crews DC

更新日期：2016-01-01 00:00:00

abstract：:A national sample of dialysis physicians was used to obtain data for a comparison of patient characteristics, comorbid conditions and treatment patterns associated with the five leading causes of end-stage renal disease (ESRD). The data are used to assess trends in physician care for ESRD patients and likely changes i...

journal_title：American journal of nephrology

authors： Radecki SE,Nissenson AR

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND/AIMS:Patients with chronic renal failure (CRF) secondary to diabetes mellitus show a high incidence of atherosclerosis with its thrombotic complications. Both CRF and type 2 diabetes mellitus (DM2) results in fibrinolysis defects causally related to atherogenesis and thrombogenesis. It is not well known whet...

journal_title：American journal of nephrology

authors： Opatrný K Jr,Zemanová P,Mares J,Vít L,Opatrná S,Sefrna F,Hejda V,Tomsů M,Eiselt J,Massry SG

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND/AIMS:Patients with chronic kidney disease (CKD) have a high prevalence of periodontal disease that may predispose to tooth loss and inflammation. The goal of this study was to test the hypotheses that a genetic rat model of progressive CKD would exhibit altered oral bone properties and that treatment with ei...

journal_title：American journal of nephrology

authors： Allen MR,Chen NX,Gattone VH 2nd,Moe SM

更新日期：2013-01-01 00:00:00

abstract：:We have recently described that in the erythrocytes from uremic patients on chronic hemodialysis, the pentose-phosphate shunt is defective, the membrane concentrations of malonyldialdehyde, resulting from peroxidation of polyunsaturated fatty acids in the membranes themselves, are increased, and the concentrations of ...

journal_title：American journal of nephrology

authors： Taccone-Gallucci M,Giardini O,Lubrano R,Mazzarella V,Bandino D,Khashan S,Mannarino O,Elli M,Cozzari M,Buoncristiani U

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Hemodialysis (HD) patients are more inactive, leading to poor functional capacity and quality of life; this may be reversed with intradialytic exercise training. To systematically evaluate the efficacy and safety of intradialytic exercise for HD patients, we conducted a meta-analysis of the pub...

journal_title：American journal of nephrology

authors： Sheng K,Zhang P,Chen L,Cheng J,Wu C,Chen J

更新日期：2014-01-01 00:00:00

abstract：:The present study evaluated thyroid hormone indices of patients with acute renal failure without other systemic illnesses (n = 12), as compared to patients with critical illnesses in the presence (n = 16) and absence (n = 6) of acute renal failure. Abnormalities in the group with acute renal failure alone included dec...

journal_title：American journal of nephrology

authors： Kaptein EM,Levitan D,Feinstein EI,Nicoloff JT,Massry SG

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Obesity is an independent risk factor for morbidity and mortality in cardiovascular diseases not only in the general population, but also in hemodialysis (HD) patients. We previously reported that an increased visceral fat area (VFA) determined using computed tomography (CT) scans was associated with atheros...

journal_title：American journal of nephrology

authors： Okamoto T,Morimoto S,Ikenoue T,Furumatsu Y,Ichihara A

更新日期：2014-01-01 00:00:00

abstract：:Bardoxolone methyl has been reported to cause detrimental cardiovascular events in the terminated BEACON Phase III human clinical trial via modulation of the renal endothelin pathway. However, the effects of bardoxolone methyl administration on the endothelin pathway in the heart are unknown. Our purpose in this persp...

journal_title：American journal of nephrology

authors： Camer D,Huang XF

更新日期：2014-01-01 00:00:00

abstract：:Skin ulceration is a well-characterized thrombotic complication of the heparin-induced thrombocytopenia (HIT) syndrome. We present the case of a 73-year-old diabetic woman nearing end-stage renal failure who developed extensive upper thigh, abdominal and buttock ulceration following initiation of subcutaneous heparin ...

journal_title：American journal of nephrology

authors： Denton MD,Mauiyyedi S,Bazari H

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Aldosterone plays an important role in fibrosis. Recent studies showed that Na(+)-H(+) exchanger isoform 1 (NHE1) is involved in mineralocorticoid-induced organ fibrosis. In this study, we examined the role of NHE1 in aldosterone-induced fibronectin accumulation in rat mesangial cells and the signaling pathw...

journal_title：American journal of nephrology

authors： Zhang M,Chen J,Lai L,You L,Lin S,Hao C,Gu Y

更新日期：2010-01-01 00:00:00

abstract：:A patient with advanced chronic renal failure secondary to polycystic kidney disease suffered an episode of volume contraction during which his urinary sodium concentration fell to less than 5 mEq daily. Urine sodium excretion remained at this level when later in his course he became clinically volume expanded. The pa...

journal_title：American journal of nephrology

authors： Danovitch GM,Jacobson E,Licht A

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Three million people in the United States are estimated to have chronic kidney disease (CKD). Management of these CKD patients in the outpatient primary care clinic setting has not been well studied. HYPOTHESIS:Primary care management of CKD can be assessed and opportunities for improvement can be identifie...

journal_title：American journal of nephrology

authors： Israni A,Korzelius C,Townsend R,Mesler D

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Estimating total body water (TBW) is crucial in determining dry weight and dialytic dose for hemodialysis patients. Several anthropometric equations have been used to predict TBW, but a more accurate method is needed. We developed an artificial neural network (ANN) to predict TBW in hemodialysis patients. M...

journal_title：American journal of nephrology

authors： Chiu JS,Chong CF,Lin YF,Wu CC,Wang YF,Li YC

更新日期：2005-09-01 00:00:00