Abstract:
:The use of indirect standardization in the assessment of the fertility of occupationally exposed workers is briefly reviewed and critiqued. The calculation of expected births in the method of Levine et al. (J Occup Med 1980;22:781-91) is modified to eliminate negative bias. An example is given using data from a 1977 survey of 60 male workers at a chemical manufacturing plant in Denver, Colorado, who were exposed to dibromochloropropane. The example illustrates how in-plant nonexposed reproductive experience provides a valuable supplement to US fertility tables which are specific only to race, birth cohort, age, and parity. It is also shown, however, that explicit control for potential confounding factors not included in the tables, such as marital status and surgical sterilization, can actually create rather than alleviate confounding error. This occurs when the additional factors co-vary in the reference population with the factors already included in the tables. For martial status, the control-induced error was readily minimized by restricting analysis to married experience at parity one or greater. For surgical sterilization, the corresponding error could not be reduced without severely compromising sample size, and hence control of this potential confounder in similar circumstances is not recommended.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Starr TB,Levine RJdoi
10.1093/oxfordjournals.aje.a113707subject
Has Abstractpub_date
1983-12-01 00:00:00pages
897-904issue
6eissn
0002-9262issn
1476-6256journal_volume
118pub_type
杂志文章abstract::Recently, the focus of research on cardiovascular risk factors has broadened because of new data demonstrating benefits of low risk (i.e., favorable) levels of all major modifiable risk factors. Most data on low risk relate to coronary heart disease, not stroke. This population-based, 12-sample, Italian study (Progett...
journal_title:American journal of epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:2006-05-15 00:00:00
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journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwq357
更新日期:2011-01-15 00:00:00
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更新日期:2002-10-01 00:00:00
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更新日期:1978-04-01 00:00:00
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更新日期:2007-07-15 00:00:00
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更新日期:2006-09-01 00:00:00
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更新日期:2005-05-15 00:00:00
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doi:10.1093/oxfordjournals.aje.a008667
更新日期:1996-05-15 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:1996-06-15 00:00:00
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更新日期:1982-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:1989-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a117642
更新日期:1995-08-01 00:00:00
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更新日期:2020-02-28 00:00:00
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journal_title:American journal of epidemiology
pub_type: 杂志文章
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更新日期:1996-08-01 00:00:00
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journal_title:American journal of epidemiology
pub_type: 杂志文章
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更新日期:1980-07-01 00:00:00
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更新日期:2017-03-01 00:00:00
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更新日期:2012-07-15 00:00:00
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