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Automated osteoporosis risk assessment by dentists: a new pathway to diagnosis.

Abstract：

:General dental practitioners use a vast amount of panoramic radiography in their routine clinical work, but valuable information about patients' osteoporotic status is not collected. There are many reasons for this, but one of the prime reasons must be the disruption involved in clinical routine with lengthy manual radiographic assessment. We have developed computer software, based on active shape modeling that will automatically detect the mandibular cortex on panoramic radiographs, and then measure its width. Automatic or semi-automatic measurement of the cortical width will indicate the osteoporotic risk of the patient. The aim of our work was to assess the computer search technique's ability to measure the mandibular cortical width and to assess its potential for detection of osteoporosis of the hip, spine and femoral neck. Mandibular cortical width was measured using the manually initialized (semi-automatic) method and, when assessed for diagnosing osteoporosis at one of the three measurement sites, gave an area under the ROC curve (A(z))=0.816 (95% CI=0.784 to 0.845) and for the automatically initialized searches, A(z)=0.759 (95% CI=0.724 to 0.791). The difference between areas=0.057 (95% Confidence interval=0.025 to 0.089), p<0.0001. For diagnosing osteoporosis at the femoral neck, mandibular cortical width derived from the manually initialized fit gave an area under the ROC curve (A(z))=0.835 (95% CI=0.805 to 0.863) and for the automatically initialized searches A(z)=0.805 (95% CI=0.773 to 0.835). The difference in A(z) values between active shape modeling search methods=0.030 (95% CI=-0.010 to 0.070), and this was not significant, p=0.138. We concluded that measurement of mandibular cortical width using active shape modeling is capable of diagnosing skeletal osteoporosis with good diagnostic ability and repeatability.

journal_name

Bone

journal_title

Bone

authors

Devlin H,Allen PD,Graham J,Jacobs R,Karayianni K,Lindh C,van der Stelt PF,Harrison E,Adams JE,Pavitt S,Horner K

doi

10.1016/j.bone.2006.10.024

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

835-42

issue

eissn

8756-3282

issn

1873-2763

pii

S8756-3282(06)00799-X

journal_volume

pub_type

杂志文章,多中心研究

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Automated osteoporosis risk assessment by dentists: a new pathway to diagnosis.