New way of regulating alternative splicing in retroviruses: the promoter makes a difference.

abstract：:Chloramphenicol affects several steps in the DNA replication of mycoplasma virus L51, a noncytocidal, naked, bullet-shaped virion containing circular single-stranded (SS) DNA of 1.5 X 10(6) daltons (4.5 kilobases). In the presence of chloramphenicol, adsorption was normal and parental SS DNA was converted to double-st...

journal_title：Journal of virology

authors： Das J,Maniloff J

更新日期：1982-12-01 00:00:00

abstract：:Entry of the budded virus form of baculoviruses into insect and mammalian cells is generally thought to occur through a low-pH-dependent endocytosis pathway, possibly through clathrin-coated pits. This insight is primarily based on (immuno)electron microscopy studies but requires biochemical support to exclude the use...

journal_title：Journal of virology

authors： Long G,Pan X,Kormelink R,Vlak JM

更新日期：2006-09-01 00:00:00

abstract：:We have evaluated the physical state and infectious nature of Kaposi's sarcoma-associated herpesvirus (KSHV) in the saliva of nine persons with past or current Kaposi's sarcoma (KS). KSHV DNA in saliva had the physical characteristics of DNA present in virions. Inoculation of 293 cells with cell-free saliva fluid resu...

journal_title：Journal of virology

authors： Vieira J,Huang ML,Koelle DM,Corey L

更新日期：1997-09-01 00:00:00

abstract：:The cytoplasmic domains of the transmembrane (TM) envelope proteins (TM-CDs) of most retroviruses have a Tyr-based motif, YXXO, in their membrane-proximal regions. This signal is involved in the trafficking and endocytosis of membrane receptors via clathrin-associated AP-1 and AP-2 adaptor complexes. We have used CD8-...

journal_title：Journal of virology

authors： Berlioz-Torrent C,Shacklett BL,Erdtmann L,Delamarre L,Bouchaert I,Sonigo P,Dokhelar MC,Benarous R

更新日期：1999-02-01 00:00:00

abstract：:The Kaposi's sarcoma-associated herpesvirus (KSHV) K1 gene encodes a polypeptide bearing an immunoreceptor tyrosine-based activation motif (ITAM) that is constitutively active for ITAM-based signal transduction. Although ectopic overexpression of K1 in cultured fibroblasts can lead to growth transformation, in vivo th...

journal_title：Journal of virology

authors： Lagunoff M,Lukac DM,Ganem D

更新日期：2001-07-01 00:00:00

abstract：:The successful use of a dendrimeric peptide to protect pigs against challenge with foot-and-mouth disease virus (FMDV), which causes the most devastating animal disease worldwide, is described. Animals were immunized intramuscularly with a peptide containing one copy of a FMDV T-cell epitope and branching out into fou...

journal_title：Journal of virology

authors： Cubillos C,de la Torre BG,Jakab A,Clementi G,Borrás E,Bárcena J,Andreu D,Sobrino F,Blanco E

更新日期：2008-07-01 00:00:00

abstract：:Taking advantage of the wide tropism of baculoviruses (BVs), we constructed a recombinant BV (BV(CAR)) pseudotyped with human coxsackie B-adenovirus receptor (CAR), the high-affinity attachment receptor for adenovirus type 5 (Ad5), and used the strategy of piggybacking Ad5-green fluorescent protein (Ad5GFP) vector on ...

journal_title：Journal of virology

authors： Granio O,Porcherot M,Corjon S,Kitidee K,Henning P,Eljaafari A,Cimarelli A,Lindholm L,Miossec P,Boulanger P,Hong SS

更新日期：2009-06-01 00:00:00

abstract：:Phosphorylation of the expressed NS5A protein of hepatitis C virus (HCV), a member of the Hepacivirus genus of the family Flaviviridae, has been demonstrated in mammalian cells and in a cell-free assay by an associated kinase activity. In this report, phosphorylation is also shown for the NS5A and NS5 proteins, respec...

journal_title：Journal of virology

authors： Reed KE,Gorbalenya AE,Rice CM

更新日期：1998-07-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) and the closely related simian immunodeficiency virus (SIV) induce profound immune dysfunction in primate species. The present studies show that cell populations infected in vitro with SIV exhibit increases in major histocompatibility complex (MHC) class II antigen expression. Ce...

journal_title：Journal of virology

authors： Kannagi M,Kiyotaki M,King NW,Lord CI,Letvin NL

更新日期：1987-05-01 00:00:00

abstract：:Several early genes of murine cytomegalovirus (MCMV) encode proteins that mediate immune evasion by interference with the major histocompatibility complex class I (MHC-I) pathway of antigen presentation to cytolytic T lymphocytes (CTL). Specifically, the m152 gene product gp37/40 causes retention of MHC-I molecules in...

journal_title：Journal of virology

authors： Holtappels R,Thomas D,Podlech J,Geginat G,Steffens HP,Reddehase MJ

更新日期：2000-02-01 00:00:00

abstract：UNLABELLED:Macrophages must react to a large number of pathogens and their effects. In chronic HIV infection, the microenvironment changes with an influx of microbial products that trigger Toll-like receptors (TLRs). That dynamic nature can be replicated ex vivo by the proinflammatory (M1-polarized) and alternatively a...

journal_title：Journal of virology

authors： Schlaepfer E,Rochat MA,Duo L,Speck RF

更新日期：2014-09-01 00:00:00

abstract：UNLABELLED:Generalized immune activation during HIV infection is associated with an increased risk of cardiovascular disease, neurocognitive disease, osteoporosis, metabolic disorders, and physical frailty. The mechanisms driving this immune activation are poorly understood, particularly for individuals effectively tre...

journal_title：Journal of virology

authors： Liang EC,Sceats L,Bayless NL,Strauss-Albee DM,Kubo J,Grant PM,Furman D,Desai M,Katzenstein DA,Davis MM,Zolopa AR,Blish CA

更新日期：2014-08-01 00:00:00

abstract：:Retroviral recombination can occur between two viral RNA molecules (intermolecular) or between two sequences within the same RNA molecule (intramolecular). The rate of retroviral intramolecular recombination is high. Previous studies showed that, after a single round of replication, 50 to 60% of retroviral recombinati...

journal_title：Journal of virology

authors： Li T,Zhang J

更新日期：2002-10-01 00:00:00

abstract：:Previous studies showed that the amino-terminal domain of Rous sarcoma virus p60v-src involved in myristylation and membrane association of the protein is required for morphological transformation and anchorage independence. Analysis of src delection mutants revealed that the amino-terminal one-third of p60v-src, incl...

journal_title：Journal of virology

authors： Calothy G,Laugier D,Cross FR,Jove R,Hanafusa T,Hanafusa H

更新日期：1987-05-01 00:00:00

abstract：UNLABELLED:Human immunodeficiency virus (HIV) seizes control of cellular cullin-RING E3 ubiquitin ligases (CRLs) to promote viral replication. HIV-1 Vpr and HIV-2/simian immunodeficiency virus (SIV) Vpr and Vpx engage the cullin4 (CUL4)-containing ubiquitin ligase complex (CRL4) to cause polyubiquitination and proteaso...

journal_title：Journal of virology

authors： Sharifi HJ,Furuya AK,Jellinger RM,Nekorchuk MD,de Noronha CM

更新日期：2014-06-01 00:00:00

abstract：:Klebsiella pneumoniae is a member of the family Enterobacteriaceae, opportunistic pathogens that are among the eight most prevalent infectious agents in hospitals. The emergence of multidrug-resistant strains of K. pneumoniae has became a public health problem globally. To develop an effective antimicrobial agent, we ...

journal_title：Journal of virology

authors： Cui Z,Shen W,Wang Z,Zhang H,Me R,Wang Y,Zeng L,Zhu Y,Qin J,He P,Guo X

更新日期：2012-12-01 00:00:00

abstract：:We have developed a complementation assay, using transiently transfected COS cells, to facilitate a molecular analysis of the herpes simplex virus type 1 glycoprotein gH. When infected by a gH-null syncytial virus, COS cells expressing wild-type gH generate infectious progeny virions and form a syncytium with neighbor...

journal_title：Journal of virology

authors： Wilson DW,Davis-Poynter N,Minson AC

更新日期：1994-11-01 00:00:00

abstract：:During the 2009 H1N1 influenza virus pandemic (pdmH1N1) outbreak, it was found that most individuals lacked antibodies against the new pdmH1N1 virus, and only the elderly showed anti-hemagglutinin (anti-HA) antibodies that were cross-reactive with the new strains. Different studies have demonstrated that prior contact...

journal_title：Journal of virology

authors： Fang Y,Banner D,Kelvin AA,Huang SS,Paige CJ,Corfe SA,Kane KP,Bleackley RC,Rowe T,Leon AJ,Kelvin DJ

更新日期：2012-02-01 00:00:00

abstract：:The unit-length genome of human herpesvirus 6 (HHV-6) consists of a single unique component (U) bounded by direct repeats DRL and DRR and forms head-to-tail concatemers during productive infection. cis-elements which mediate cleavage and packaging of progeny virions (a sequences) are found at the termini of all herpes...

journal_title：Journal of virology

authors： Thomson BJ,Dewhurst S,Gray D

更新日期：1994-05-01 00:00:00

abstract：:CD8+ T cells were previously shown to be important in preventing lymphoproliferation and immunodeficiency following infection of murine AIDS (MAIDS)-resistant mice with the LP-BM5 mixture of murine leukemia viruses. To further evaluate the mechanisms contributing to MAIDS resistance, we studied mice lacking CD8+ T cel...

journal_title：Journal of virology

authors： Tang Y,Hügin AW,Giese NA,Gabriele L,Chattopadhyay SK,Fredrickson TN,Kägi D,Hartley JW,Morse HC 3rd

更新日期：1997-03-01 00:00:00

abstract：:When ts7, a temperature-sensitive (ts) mutant of influenza B/Kanagawa/73 virus, infected MDCK cells at the nonpermissive temperature (37.5 degrees C), infectious virus was produced at very low levels compared with the yield at the permissive temperature (32 degrees C) and hemagglutinating activity and enzymatic activi...

journal_title：Journal of virology

authors： Yamamoto-Goshima F,Maeno K,Morishita T,Ueda M,Fujita Y,Nakajima K,Yoshii S

更新日期：1994-02-01 00:00:00

abstract：:We have identified a cytomegalovirus virion protein capable of modulating the rapid induction of an interferon-like response in cells that follows virus binding and penetration. Functional genomics revealed a role for the major cytomegalovirus structural protein, pp65 (ppUL83), in counteracting this response. The unde...

journal_title：Journal of virology

authors： Abate DA,Watanabe S,Mocarski ES

更新日期：2004-10-01 00:00:00

abstract：:Human papillomavirus (HPV) is a strongly conserved DNA virus, high-risk types of which can cause cervical cancer in persistent infections. The most common type found in HPV-attributable cancer is HPV16, which can be subdivided into four lineages (A to D) with different carcinogenic properties. Studies have shown HPV16...

journal_title：Journal of virology

authors： van der Weele P,Meijer CJLM,King AJ

更新日期：2017-09-12 00:00:00

abstract：:The characteristics of a rotaviruslike (SBR) virus isolated from striped bass (Morone saxatilis) were examined following purification of viruses from infected cell cultures. Virions had a double-layered capsid of icosahedral symmetry and a diameter of 75 nm. Purified viruses contained five polypeptides ranging in mole...

journal_title：Journal of virology

authors： Samal SK,Dopazo CP,McPhillips TH,Baya A,Mohanty SB,Hetrick FM

更新日期：1990-11-01 00:00:00

abstract：:Recently, we showed that the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) VP80 protein is essential for the formation of both virion types, budded virus (BV) and occlusion-derived virus (ODV). Deletion of the vp80 gene did not affect assembly of nucleocapsids. However, these nucleocapsids were not ...

journal_title：Journal of virology

authors： Marek M,Merten OW,Galibert L,Vlak JM,van Oers MM

更新日期：2011-06-01 00:00:00

abstract：:The ICP18.5 gene (UL28) of herpes simplex virus type 1 is a member of a well-conserved gene family among herpesviruses and is thought to play a role in localization of viral glycoproteins. We have cloned, sequenced, and expressed the entire pseudorabies virus (PRV) ICP18.5 open reading frame in Escherichia coli as a C...

journal_title：Journal of virology

authors： Pederson NE,Enquist LW

更新日期：1991-07-01 00:00:00

abstract：:Two foot-and-mouth disease virus (FMDV) genome sequences have been determined for isolates collected from recent field outbreaks in North Africa (Egypt) and the Middle East (Palestinian Autonomous Territories). These data represent the first examples of complete genomic sequences for the FMDV SAT 2 topotype VII, which...

journal_title：Journal of virology

authors： Valdazo-González B,Knowles NJ,Hammond J,King DP

更新日期：2012-08-01 00:00:00

abstract：:Myxomatosis is a recurrent problem on rabbit farms throughout Europe despite the success of vaccines. To identify gene variations of field and vaccine strains that may be responsible for changes in virulence, immunomodulation, and immunoprotection, the genomes of 6 myxoma virus (MYXV) strains were sequenced: German fi...

journal_title：Journal of virology

authors： Braun C,Thürmer A,Daniel R,Schultz AK,Bulla I,Schirrmeier H,Mayer D,Neubert A,Czerny CP

更新日期：2017-01-31 00:00:00

abstract：:Zika virus (ZIKV) envelope (E) protein is the major target of neutralizing antibodies in infected hosts and thus represents a candidate of interest for vaccine design. However, a major concern in the development of vaccines against ZIKV and the related dengue virus is the induction of cross-reactive poorly neutralizin...

journal_title：Journal of virology

authors： De Lorenzo G,Tandavanitj R,Doig J,Setthapramote C,Poggianella M,Sanchez-Velazquez R,Scales HE,Edgar JM,Kohl A,Brewer J,Burrone OR,Patel AH

更新日期：2020-12-09 00:00:00

abstract：:Kinetic analysis showed that the Ki values and the Ki/Km ratios for mutated, recombinant M184V human immunodeficiency virus type 1 reverse transcriptase (RT) for (-)2'-dideoxy-3'-thiacytidine triphosphate (3TCTP) were 35-fold higher than the equivalent values for wild-type RT but only about twice as high as the equiva...

journal_title：Journal of virology

authors： Quan Y,Gu Z,Li X,Li Z,Morrow CD,Wainberg MA

更新日期：1996-08-01 00:00:00