Total and intraabdominal fat distribution in preadolescents and adolescents: measurement with MR imaging.

Abstract:

PURPOSE:To prospectively correlate single- and multisection magnetic resonance (MR) imaging measurements with clinical measurements for assessment of abdominal adipose tissue volumes in healthy (control subjects), overweight, and diabetic overweight preadolescents and adolescents. MATERIALS AND METHODS:The study was approved by the institutional internal review board and was HIPAA compliant. Informed consent was obtained from parents, and assent was obtained from control subjects and patients. Thirty total study subjects (20 male, 10 female; age range, 10-18 years; mean, 14.5 years) underwent MR imaging, anthropometric measurement, and dual x-ray absorptiometry (DXA). A computer-assisted software program was used to quantify subcutaneous, visceral, and total abdominal adipose tissue volumes. Single-section measurements at disk space L4-L5 and whole-abdominal multisection measurements were compared, and each method was tested for correlations with anthropometric and DXA measurements with Spearman rho and Pearson correlation (r) coefficients. Single- and multisection image analyses required 5 and 25 minutes per subject, respectively. RESULTS:There was a high degree of correlation between single- and multisection MR imaging methods for measurement of subcutaneous (r = 0.97), visceral (r = 0.96), and total abdominal fat (r = 0.97). MR imaging fat measurements strongly correlated with anthropometric measurements (rho correlation range, 0.81-0.96; P

journal_name

Radiology

journal_title

Radiology

authors

Siegel MJ,Hildebolt CF,Bae KT,Hong C,White NH

doi

10.1148/radiol.2423060111

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

846-56

issue

3

eissn

0033-8419

issn

1527-1315

pii

2423060111

journal_volume

242

pub_type

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