Presurgical evaluation of the motor hand area with functional MR imaging in patients with tumors and dysplastic lesions.

Abstract:

PURPOSE:To test an optimized functional magnetic resonance (MR) imaging procedure to depict the motor hand representation area (HRA) in patients with epilepsy lesions near the central sulcus. MATERIALS AND METHODS:Fast low-angle shot MR imaging was performed with an oblique single-section imaging technique in eight control subjects (10 hemispheres) and six patients (12 hemispheres). Three series of five activation images (obtained while subjects performed repetitive finger-to-thumb opposition movements) and five rest images were acquired. Each hemisphere was studied in three adjacent sections. Difference maps (obtained with simple subtraction between activation and rest images) were compared with t-test maps. RESULTS:In control subjects, the HRA was visible in 27 of 30 sections. Qualitatively, activation was seen better on t-test maps in 14 and on difference maps in four of these sections. In all patients, motor activation could be seen in the hemisphere that contained the lesion. This activation was considered normal in four patients. In two patients, the HRA was deformed. Functional MR imaging activation in the motor area was confirmed with Penfield stimulation in five patients. CONCLUSION:Functional MR imaging findings in the preoperative assessment of dysplastic lesions around the central sulcus are the same as for tumors. t-test maps are superior to difference maps in the treatment of motor functional MR imaging data.

journal_name

Radiology

journal_title

Radiology

authors

Achten E,Jackson GD,Cameron JA,Abbott DF,Stella DL,Fabinyi GC

doi

10.1148/radiology.210.2.r99ja31529

subject

Has Abstract

pub_date

1999-02-01 00:00:00

pages

529-38

issue

2

eissn

0033-8419

issn

1527-1315

journal_volume

210

pub_type

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