Abstract:
:To determine pulmonary deposition and clearance of inhaled volcanic ash, rats received a single 60-min, nose-only exposure to neutron-activated ash. Over a period of 128 days after exposure, the rats were sacrificed in groups of five animals. Lungs were analyzed for the radionuclide tracers 46Sc, 59Fe, and 60Co by gamma-ray spectrometry. The alveolar ash burdens, determined by the radionuclides 46Sc and 59Fe, are in good agreement for the majority of samples analyzed, indicating ash particulate levels in the lungs, rather than leached radionuclides. The ash deposition estimates based on 60Co were appreciably lower for the lungs, indicating that 60Co leached from the ash. Approximately 110 micrograms ash, or 6% of the inhaled ash, was initially retained in the deep lung. The biological half-time of the alveolar ash burden was 39 days. After 90 days, the mean lung burden had decreased to about 20% of its initial value; 128 days after exposure, about 10% remained.
journal_name
Environ Resjournal_title
Environmental researchauthors
Wehner AP,Wilerson CL,Stevens DLdoi
10.1016/0013-9351(84)90129-4subject
Has Abstractpub_date
1984-10-01 00:00:00pages
211-7issue
1eissn
0013-9351issn
1096-0953pii
0013-9351(84)90129-4journal_volume
35pub_type
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journal_title:Environmental research
pub_type: 杂志文章
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journal_title:Environmental research
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journal_title:Environmental research
pub_type: 杂志文章
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更新日期:1984-02-01 00:00:00
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journal_title:Environmental research
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更新日期:2015-05-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
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journal_title:Environmental research
pub_type: 杂志文章
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更新日期:2019-05-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2016-05-01 00:00:00
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journal_title:Environmental research
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pub_type: 杂志文章,meta分析,评审
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更新日期:2017-11-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(83)90117-2
更新日期:1983-12-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(87)80013-0
更新日期:1987-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108903
更新日期:2020-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2011.03.002
更新日期:2011-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.envres.2011.07.009
更新日期:2011-11-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110470
更新日期:2020-11-18 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109802
更新日期:2020-09-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章,评审
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更新日期:2001-02-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110358
更新日期:2020-10-24 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.11.024
更新日期:2019-02-01 00:00:00