Release of serotonin from perikarya in cat nodose ganglia.

abstract：:An electrophysiological approach has been used to trace the central course of individual C fibres from a cutaneous (sural) and muscle (gastrocnemius) nerve in anaesthetized rats. Single C fibres were recorded from the central part of cut peripheral nerves and a glass micropipette used to map the spinal cord with low t...

journal_title：Brain research

authors： McMahon SB,Wall PD

更新日期：1985-12-16 00:00:00

abstract：:The effects of the 8-alpha-amino-ergoline CU 32-085 on central dopamine neuronal systems was investigated. Two h after administration of CU 32-085 a slight increase of dopamine levels was observed in the nucleus caudatus-putamen. Radioligand binding studies in vitro have shown that CU 32-085 has a low affinity for str...

journal_title：Brain research

authors： Fuxe K,Agnati L,Mascagni F,Kuga S,Helmer-Matyjek E,Goldstein M

更新日期：1985-03-04 00:00:00

abstract：:Some occluded arteries of acute ischemic stroke (AIS) patients are not recanalized, even if thrombolytic therapy is performed. Considering such clinical settings, we examined the potential cerebroprotective efficacy of TAK-937, a novel cannabinoid receptor agonist, in young adult and aged rats with a permanent middle ...

journal_title：Brain research

authors： Murakami K,Suzuki M,Suzuki N,Hamajo K,Tsukamoto T,Shimojo M

更新日期：2013-08-14 00:00:00

abstract：:The concentrations of GABA, glutamate, aspartate, glycine, taurine, glutamine, asparagine and alanine were determined in the CSF of 10 Senegalese baboons (Papio papio) following initial ketamine anaesthesia and subsequent administration (4 h later) of different compounds known to alter either inhibitory or excitatory ...

journal_title：Brain research

authors： Valin A,Voltz C,Naquet R,Lloyd KG

更新日期：1991-01-04 00:00:00

abstract：:After treatment with pentylenetetrazol (PTZ), cholecystokinin (CCK) mRNA and CCK-like immunoreactivity (CCK-LI) levels were determined in rat hippocampus and cortex at different time points. In the temporal cortex treatment with 60 mg/kg PTZ, i.p., induced increases of CCK mRNA and CCK-LI levels at 2 days after the in...

journal_title：Brain research

authors： Takeda K,Nakata K,Takahashi S,Chikuma T,Kato T

更新日期：1998-01-01 00:00:00

abstract：:Effects of intracranial self-stimulation of central 'punishment areas' were studied on an operant conditioning of vertical eye movements in the midpontine pretrigeminal cats as well as in the encéphale isolé cats. In 36 pretrigeminal cats, the ventromedial hypothalamus (VMH), basal amygdaloid nuclei (AMY), dorsal cent...

journal_title：Brain research

authors： Ikegami S,Kawamura H

更新日期：1981-12-21 00:00:00

abstract：:We have previously described a rodent model of brief (30 min) middle cerebral artery occlusion followed by reperfusion, in which infarction develops gradually, reaching completion more than 3 days after ischemia, accompanied by morphological, biochemical, and pharmacological evidence of apoptosis. In the present study...

journal_title：Brain research

authors： Snider BJ,Du C,Wei L,Choi DW

更新日期：2001-11-02 00:00:00

abstract：:Current and voltage responses elicited by increasing or decreasing the concentration of L-glutamate or its analog kainate around isolated cone horizontal cells were measured with patch pipettes using the whole cell recording configuration. Application of these photoreceptor transmitter agonists induced inward currents...

journal_title：Brain research

authors： Perlman I,Knapp AG,Dowling JE

更新日期：1989-05-15 00:00:00

abstract：:The neurotoxic effects of amyloid-beta(1-42) and amyloid-beta(25-35) (A beta) on cholinergic and acetylcholinesterase-positive neurons were investigated in primary cultures derived from embryonic 18-day-old rat basal forebrain. After various time intervals, the cultures were treated with 1, 5, 10 or 20 microM A beta f...

journal_title：Brain research

authors： Kasa P Sr,Papp H,Kasa P Jr,Pakaski M,Balaspiri L

更新日期：2004-02-13 00:00:00

abstract：:The pattern of generation of neurons in the albino rat superior colliculus has been studied in adult and fetal material. Neurons are generated between embryonic days 12 to 17, with rostrolateral colliculus in advance of caudomedial parts. More of the cells contributing to the deeper layers are generated early, while m...

journal_title：Brain research

authors： Mustari MJ,Lund RD,Graubard K

更新日期：1979-03-23 00:00:00

abstract：:Beta-amyloid (Aβ)-mediated inflammation plays a critical role in the initiation and progression of Alzheimer׳s disease (AD). Anti-inflammatory treatment may provide therapeutic benefits. In this study, the effect of hydroxy-safflor yellow A (HSYA) on Aβ1-42-induced inflammation in AD mice was investigated and the unde...

journal_title：Brain research

authors： Zhang ZH,Yu LJ,Hui XC,Wu ZZ,Yin KL,Yang H,Xu Y

更新日期：2014-05-14 00:00:00

abstract：:Previously we reported that several microRNAs (miRNA) are upregulated following experimentally induced traumatic brain injury (TBI) using both in vivo and in vitro approaches. Specific miRNAs were found to be sensitive to therapeutic hypothermia and may therefore be important targets for neuroprotective strategies. In...

journal_title：Brain research

authors： Truettner JS,Motti D,Dietrich WD

更新日期：2013-10-02 00:00:00

abstract：:By utilizing the microinjection of low nanoliter volumes of convulsant drug and recording from the injection site, we have been able to electrophysiologically identify a layer of cat striate cortex that is most sensitive to the epileptogenic effects of penicillin. This band encompasses cortical depths of approximately...

journal_title：Brain research

authors： Chatt AB,Ebersole JS

更新日期：1982-06-10 00:00:00

abstract：:Quantitative and qualitative data are reported for single cerebral hemispheric neurons in a 3-dimensional hydrated collagen lattice (HCL) culture system. Individual neurons not in contact with other cells or cell processes, including synapses, rapidly displayed two morphologically distinct classes of processes that co...

journal_title：Brain research

authors： Coates PW

更新日期：1986-02-01 00:00:00

abstract：:Previous studies on the processing of fractions and proportions focused mainly on the processing of their overall magnitude information in the intraparietal sulcus (IPS). However, the IPS is also associated with domain-general cognitive functions beyond processing overall magnitude, which may nevertheless be involved ...

journal_title：Brain research

authors： Mock J,Huber S,Bloechle J,Bahnmueller J,Moeller K,Klein E

更新日期：2019-07-01 00:00:00

abstract：:The rapid saltatory motion of intra-axonal particles detected by dark-field microscopy in myelinated axons isolated from sciatic nerves of adult Xenopus laevis was inhibited by colchicine or vinblastine at a concentration of larger than or equal to 0.1 mM. Both the predominant somatopetal transport and the somatofugal...

journal_title：Brain research

authors： Hammond GR,Smith RS

更新日期：1977-06-10 00:00:00

abstract：:In rats kainic acid-induced seizures were accompanied by time-dependent cerebral cysteinyl-leukotriene (LT) and prostaglandin (PG) F2 alpha formation. Cysteinyl-LT were identified in the rat brain tissue extracts by their immunoreactive properties and their retention times upon reversed phase HPLC profiling. In perfus...

journal_title：Brain research

authors： Simmet T,Tippler B

更新日期：1990-05-07 00:00:00

abstract：:The modulation of tetrodotoxin-sensitive (TTX-S) and slow tetrodotoxin-resistant (TTX-R) sodium currents in rat dorsal root ganglion neurons by ATP was studied using the whole-cell patch-clamp method. The effects of ATP on two types of sodium currents were either stimulatory or inhibitory depending on the kinetic para...

journal_title：Brain research

authors： Joo Choi E,Hong MP,Kyoo Shin Y,Soo Lee C,Park M,Song JH

更新日期：2003-04-04 00:00:00

abstract：:Intraocular injections of tetrodotoxin were used to block activity for 27 days in normal fish and for the first 27 or 31 days of regeneration in fish with one optic nerve crushed. Synaptic activity was then assessed by a current source-density analysis of field potentials evoked by optic nerve shock at different times...

journal_title：Brain research

authors： Schmidt JT,Edwards DL,Stuermer C

更新日期：1983-06-13 00:00:00

abstract：:The mouse auditory neurons, hair cells and their supporting cells in the cochlea are considered to be generated mainly in the embryonic days and to be sustained throughout the whole life. In the present study, however, we observed that auditory ganglion cells in the spiral ganglia undergo apoptosis and mitosis in the ...

journal_title：Brain research

authors： Kamiya K,Takahashi K,Kitamura K,Momoi T,Yoshikawa Y

更新日期：2001-05-18 00:00:00

abstract：:In the brain, nitric oxide (NO) has been identified as a messenger molecule and a mediator of excitatory amino acid-induced neurotoxicity. In this study, the effects of NO on serum-induced mitogenesis and cell proliferation of the cerebellar glial cells were assessed. NO-generating agent, S-nitroso-N-acetylpenicillami...

journal_title：Brain research

authors： Garg UC,Devi L,Turndorf H,Goldfrank LR,Bansinath M

更新日期：1992-10-02 00:00:00

abstract：:Bilateral quisqualic acid-induced lesions of the nucleus basalis magnocellularis (nbm) in rats disrupted the expression of latent inhibition, a phenomenon thought to be dependent upon selective attention processes. Since grafts of adrenal chromaffin cells to the cerebral cortex of nbm-lesioned rats have been shown to ...

journal_title：Brain research

authors： Welner SA,Rousse I,Rochford J

更新日期：1995-02-13 00:00:00

abstract：:We investigated the effect of ketogenic diet (KD) on clusterin accumulation in the kainic acid (KA)-induced seizure model. Two days after KA administration, strong clusterin-like immunoreactivity (IR) was detected in the hippocampus in the normal diet (ND)-fed mice. But in the KD-fed mice, few clusterin-like IR was de...

journal_title：Brain research

authors： Noh HS,Kim DW,Kang SS,Cho GJ,Choi WS

更新日期：2005-04-25 00:00:00

abstract：:Stellate ganglion block (SGB) is a blockade of sympathetic ganglia innervating the head and neck, and is known to function through vasodilation of the target region. However, the effectiveness of SGB in relieving cerebral vasospasm (CVS) through dilation of intracerebral vessels has not been evaluated. The aim of the ...

journal_title：Brain research

authors： Hu N,Wu Y,Chen BZ,Han JF,Zhou MT

更新日期：2014-10-17 00:00:00

abstract：:Genetic abnormalities in amyloid precursor protein (APP) are associated with Down's syndrome and familial Alzheimer's disease where hallmark plaques contain A beta peptides derived from APP. Both APP and its derivatives are implicated in neurodegenerative processes and may play important physiological and pathophysiol...

journal_title：Brain research

authors： Senechal Y,Prut L,Kelly PH,Staufenbiel M,Natt F,Hoyer D,Wiessner C,Dev KK

更新日期：2008-12-03 00:00:00

abstract：:Oxidative stress plays an important role in neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease. Methamphetamine (METH) is an amphetamine analog that causes degeneration of the dopaminergic system in mammals and subsequent oxidative stress. In our present study, we have used immortalized hu...

journal_title：Brain research

authors： Zhang X,Banerjee A,Banks WA,Ercal N

更新日期：2009-06-12 00:00:00

abstract：:A double-label immunofluorescence technique was used to demonstrate that immunoreactivities for the functionally antagonistic neuropeptides enkephalin and cholecystokinin octapeptide (CCK) are co-localized within individual neurons and processes in discrete areas of rat midbrain and forebrain. Coexistence was most pro...

journal_title：Brain research

authors： Gall C,Lauterborn J,Burks D,Seroogy K

更新日期：1987-02-17 00:00:00

abstract：:In alert monkeys, some prefrontal neurons located in the superior dorsolateral area were activated to acoustic stimuli delivered in a restricted range of directions with respect to the animal's head. The effective direction was usually contralateral to the animal. The function of the auditory neurons in connection to ...

journal_title：Brain research

authors： Azuma M,Suzuki H

更新日期：1984-04-30 00:00:00

abstract：:Antisense oligodeoxynucleotide (AS ODN) probes directed against the alpha-subunit of different G-proteins have been used to differentiate feeding responses in rats elicited by different opioid agonists, including morphine, beta-endorphin and dynorphin. Furthermore, antisense probes directed against G(o)alpha, but not ...

journal_title：Brain research

authors： Hadjimarkou MM,Silva RM,Rossi GC,Pasternak GW,Bodnar RJ

更新日期：2002-11-15 00:00:00

abstract：:Rats with bilateral striatal cholinergic lesions induced by the neurotoxin AF64A were found to have increased spontaneous nocturnal locomotor activity as measured in terms of the amount of time spent moving, the total distance traveled and the number of episodes and time of stereotypic behaviors. No significant differ...

journal_title：Brain research

authors： Sandberg K,Sanberg PR,Coyle JT

更新日期：1984-05-14 00:00:00