Botulinum toxin treatment for anal fissure.

Abstract:

OBJECTIVES:To evaluate the effectiveness of Botulinum toxin injection in the treatment of anal fissure. METHODS:38 patients (22 males, 16 females; mean age (SD) of 33.3 (8.3) years) who have presented to Surgical Outpatient Clinic at Al Ain Hospital, United Arab Emirates, with anal fissure in the period between June 2000 and September 2001 and treated with Botulinum toxin injection were retrospectively studied. They were followed up for at least 8 weeks to evaluate the effects of treatment. RESULTS:Treatment with Botulinum toxin was effective in 89% of patients with chronic uncomplicated anal fissure. Two patients experienced minor incontinence in the form of a fecal soiling which disappeared later. CONCLUSION:Botulinum toxin injection is an effective alternative for surgery for treatment of uncomplicated idiopathic anal fissure. Surgery should be offered to patients who do not improve with Botulinum toxin injection and to those with complicated anal fissure.

journal_name

Afr Health Sci

journal_title

African health sciences

authors

Radwan MM,Ramdan K,Abu-Azab I,Abu-Zidan FM

doi

10.5555/afhs.2007.7.1.14

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

14-7

issue

1

eissn

1680-6905

issn

1729-0503

journal_volume

7

pub_type

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