Evaluation of the diagnostic performance and operational characteristics of four rapid immunochromatographic syphilis tests in Burkina Faso.

Abstract:

BACKGROUND AND OBJECTIVE:Little information is available on the rapid diagnostic testing for syphilis in Burkina Faso. The objectives of the study were (i) to assess the sensitivity and specificity of four on site rapid tests in comparison with Treponema pallidum haemagglutination assay (TPHA) as a gold standard and (ii) to evaluate the operational characteristics of those tests among health workers in a maternity unit. METHODS:Four rapid syphilis tests commercially available in Burkina Faso were evaluated using archived serum samples and Treponema pallidum hemagglutination assay (TPHA) as the gold standard. Blood samples were collected between November 2011 and June 2012 from blood donors at the Regional Blood Transfusion Center of Ouagadougou. The sensitivity and specificity of the tests were calculated. Evaluation of operational characteristics such as clarity of pamphlet, complexity of technique, duration, was conducted in a first-level healthcare center with health workers in maternity unit. RESULTS:Alere DetermineTM Syphilis was the most sensitive of the four rapid syphilis tests evaluated. It was followed by SD Bioline Syphilis 3.0, Cypress Diagnostics Syphilis Quick test and Accu-Tell ® Rapid Anti-TP, which was the least sensitive. The four tests demonstrated a good diagnostic specificity for syphilis (95-98%), and healthcare workers found them easy to use. CONCLUSIONS:The study allowed confirming the good performance of three of four rapid syphilis tests in Burkina Faso. More research will be conducted to assess the feasibility of introducing selected rapid tests for syphilis in antenatal care services.

journal_name

Afr Health Sci

journal_title

African health sciences

authors

Bocoum FY,Ouédraogo H,Tarnagda G,Kiba A,Tiendrebeogo S,Bationo F,Liestman B,Diagbouga S,Zarowsky C,Traoré RO,Kouanda S

doi

10.4314/ahs.v15i2.8

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

360-7

issue

2

eissn

1680-6905

issn

1729-0503

pii

jAFHS.v15.i2.pg360

journal_volume

15

pub_type

杂志文章
  • Impact of weight reduction on insulin resistance, adhesive molecules and adipokines dysregulation among obese type 2 diabetic patients.

    abstract:Background:Type 2 diabetes mellitus is usually related to vascular problems and is associated with impairment in endothelial function characterized by impaired endothelial-dependent vasodilation and increased platelet adhesion. There is limitation in clinical studies that have addressed the beneficial effects of weight...

    journal_title:African health sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.4314/ahs.v18i4.5

    authors: Abd El-Kader SM,Al-Jiffri OH

    更新日期:2018-12-01 00:00:00

  • In vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, quinine, mefloquine and halofantrine in Abidjan (Côte d'Ivoire).

    abstract:BACKGROUND:Malaria is the primary cause of hospitalization in Côte d'Ivoire. Early treatment is one of the strategies to control this illness. However, the spread of resistance of Plasmodium falciparum to antimalarial drugs can seriously compromise this strategy. OBJECTIVES:The aim of this study was to assess the in v...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Yavo W,Bla KB,Djaman AJ,Assi SB,Basco LK,Mazabraud A,Koné M

    更新日期:2010-06-01 00:00:00

  • Socio-economic status and hunger among orphans and vulnerable children households in Lagos State, Nigeria.

    abstract:Background:HIV/AIDS has contributed to increasing orphans and vulnerable children in Nigeria. A measure of vulnerability is household hunger. Objective:To assess level of household hunger and associated factors among OVC households in Lagos State. Methods:A cross-sectional survey of 1300 OVC households in 5 selected ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i2.47

    authors: Bamgboye E,Odusote T,Olusanmi I,Akinyemi J,Bidemi Y,Adebowale A,Gbenga A,Ladipo O

    更新日期:2020-06-01 00:00:00

  • Clinical presentation and outcome of autosomal dominant polycystic kidney disease in Nigeria.

    abstract:Introduction:Autosomal Dominant Polycystic Kidney Disease (ADPKD) is presumably rare in Africa. Knowledge about the disease in Nigeria is limited as demonstrated by scanty articles on the subject. Objectives:To determine the pattern of clinical presentation and outcome of ADPKD among ADPKD patients. Method:ADPKD subj...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v18i3.25

    authors: Arogundade FA,Akinbodewa AA,Sanusi AA,Okunola O,Hassan MO,Akinsola A

    更新日期:2018-09-01 00:00:00

  • Neurologic infections in a Nigerian university teaching hospital.

    abstract:BACKGROUND:Neurologic infections are an important cause of morbidity and mortality especially worldwide but much more in the African continent. The frequency of the different types of neurologic infections and their mortality in this part of Nigeria is not known. OBJECTIVES:To review cases admitted into the main terti...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.5555/afhs.2006.6.1.55

    authors: Chapp-Jumbo EN

    更新日期:2006-03-01 00:00:00

  • Salivary flow, amylase, and total protein in hospitalized patients with HIV infection / AIDS complications.

    abstract:Background:Saliva is a complex secretion produced daily by the salivary glands. Saliva consists mainly of water, enzymes, ions and amino acids and performs several important functions in oral health. Objective:The aim of this study was to investigate the flow rate and concentrations of amylase and total proteins in th...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i2.7

    authors: de Oliveira NC,de Oliveira TC,Klamas VC,Ventura MA,Kamei AA,Naka JY,Brancher JA,de Lima AAS

    更新日期:2020-06-01 00:00:00

  • Diagnostic utility of clinical and biochemical parameters in pancreatic head malignancy patients with normal carbohydrate antigen 19-9 levels.

    abstract:BACKGROUND:Carbohydrate antigen (CA)19-9 that is the most widely used biomarker for pancreatic cancer has certain limitations in diagnosis, which results in a tough job to distinguish pancreatic cancer from benign tumors with normal CA19-9. The aim of this study was to investigate the diagnostic utility of clinical par...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v15i1.17

    authors: Jin X,Wu Y

    更新日期:2015-03-01 00:00:00

  • Rapid screening for co-infection of HIV and HCV in pregnant women in Benin City, Edo State, Nigeria.

    abstract:BACKGROUND:Human Immunodeficiency virus (HIV) and Hepatitis C virus (HCV) are both major global health concerns as they cause high mortality and morbidity in the developing countries. However, while data exists for the co-infection in other countries, little or no information can be found with regard to the sero-preval...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Duru MU,Aluyi HS,Anukam KC

    更新日期:2009-09-01 00:00:00

  • Classification and description of chronic pain among HIV positive patients in Uganda.

    abstract:Introduction:Chronic pain classification in HIV positive patients is essential for diagnosis and treatment. However, this is rarely done despite association with poor outcomes. Methods:A cross-sectional survey of 345 consented patients at a specialized HIV care center in Uganda was conducted. Chronic pain was defined ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v19i2.20

    authors: Mwesiga EK,Kaddumukasa M,Mugenyi L,Nakasujja N

    更新日期:2019-06-01 00:00:00

  • Biochemical markers of mineral bone disorder in South African patients on maintenance haemodialysis.

    abstract:BACKGROUND AND OBJECTIVE:Despite the high mortality and morbidity associated with abnormalities in mineral and bone metabolism in haemodialysis patients, there is limited data on the pattern of mineral bone disorder in African CKD population. Therefore, the purpose of this study was to describe the pattern of mineral b...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v17i2.19

    authors: Waziri B,Duarte R,Naicker S

    更新日期:2017-06-01 00:00:00

  • HIV counseling and testing practices among clients presenting at a market HIV clinic in Kampala, Uganda: a cross-sectional study.

    abstract:BACKGROUND:Uptake of HIV counseling and testing (HCT) among informal sector workers is not well documented. OBJECTIVE:To assess HCT practices among clients presenting for HIV services at a market HIV clinic in Kampala, Uganda. METHODS:Between August 1 and September 15, 2009, clients presenting for HIV services at a m...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v17i3.15

    authors: Matovu JK,Bukuluki PW,Mafigiri DK,Mudondo H

    更新日期:2017-09-01 00:00:00

  • Endoscopic capacity in West Africa.

    abstract:BACKGROUND:Levels of endoscopic demand and capacity in West Africa are unclear. OBJECTIVES:This paper aims to: 1. describe the current labor and endoscopic capacity, 2. quantify the impact of a mixed-methods endoscopy course on healthcare professionals in West Africa, and 3. quantify the types of diagnoses encountered...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v16i1.44

    authors: Perl D,Leddin D,Bizos D,Veitch A,N'Dow J,Bush-Goddard S,Njie R,Lemoine M,Anderson ST,Igoe J,Anandasabapathy S,Shah B

    更新日期:2016-03-01 00:00:00

  • Botulinum toxin treatment for anal fissure.

    abstract:OBJECTIVES:To evaluate the effectiveness of Botulinum toxin injection in the treatment of anal fissure. METHODS:38 patients (22 males, 16 females; mean age (SD) of 33.3 (8.3) years) who have presented to Surgical Outpatient Clinic at Al Ain Hospital, United Arab Emirates, with anal fissure in the period between June 2...

    journal_title:African health sciences

    pub_type: 临床试验,杂志文章

    doi:10.5555/afhs.2007.7.1.14

    authors: Radwan MM,Ramdan K,Abu-Azab I,Abu-Zidan FM

    更新日期:2007-03-01 00:00:00

  • Prevalence and correlates of snoring among adults in Nigeria.

    abstract:INTRODUCTION:Snoring is a common sleep problem with significant public health concerns. Studies have characterized this in most developed countries. Hitherto there have been no published studies on this subject in Nigeria. OBJECTIVES:To determine the prevalence and correlates of snoring in addition to morbidity in an ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Adewole OO,Adeyemo H,Ayeni F,Anteyi EA,Ajuwon ZO,Erhabor GE,Adewole TT

    更新日期:2008-06-01 00:00:00

  • Factors associated with depression and suicide among patients with diabetes mellitus and essential hypertension in a Nigerian teaching hospital.

    abstract:BACKGROUND:Diabetes mellitus (DM) and essential hypertension are chronic medical conditions that place a lot of burden on patients. The presence of depression and suicidal behaviour may worsen the prognosis. OBJECTIVE:To assess the prevalence of depression and suicidal behaviour in subjects with diabetes mellitus and ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v13i1.10

    authors: Igwe MN,Uwakwe R,Ahanotu CA,Onyeama GM,Bakare MO,Ndukuba AC

    更新日期:2013-03-01 00:00:00

  • Sero-prevalence and associated factors of Helicobacter pylori infection among adult patients with dyspepsia attending the gastroenterology unit in a tertiary hospital in Mwanza, Tanzania.

    abstract:BACKGROUND:Prevalence of H.pylori infection varies greatly between populations in different countries. This study was conducted to determine the magnitude of H.pylori among adult patients with dyspepsia attending the gastroenterology unit at Bugando medical centre. METHODS:A cross sectional study involving 202 dyspept...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v16i3.7

    authors: Jaka H,Mushi MF,Mirambo MM,Wilson L,Seni J,Mtebe M,Mshana SE

    更新日期:2016-09-01 00:00:00

  • Unorthodox ophthalmic preparations on the Ghanaian market: a potential risk for ocular and enteric infections.

    abstract:Purpose:Microbial contamination of orthodox ophthalmic preparations poses a serious threat to the user by causing ocular infections. There is no such information about unorthodox ophthalmic preparations in a medical pluralistic system such as Ghana. The aim of this study was to assess unorthodox ophthalmic medications ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v20i1.58

    authors: Kyei S,Dogbadze E,Tagoh S,Mwanza E

    更新日期:2020-03-01 00:00:00

  • Young patient's age determines pterygium recurrence after surgery.

    abstract:BACKGROUND:It is not clear whether demographic or pterygium characteristics or limbal stem cell deficiency determine pterygium recurrence after surgery. PURPOSE:To determine whether the demographic, pterygium characteristics, or limbal stem cell deficiency determine pterygium recurrence after excision. METHODS:Of 190...

    journal_title:African health sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.4314/ahs.v14i1.11

    authors: Anguria P,Ntuli S,Carmichael T

    更新日期:2014-03-01 00:00:00

  • Impact of medication and psychological behaviour assessment by community pharmacists in type 2 diabetes mellitus patients after hospital stay.

    abstract:BACKGROUND:Drug related problem (DRPs) is a key factor which will affect the outcome of therapy and safety. OBJECTIVE:To assess the DRPs in type 2 diabetes mellitus (T2DM) patients and psychological aspects of patients by community pharmacists to observe the rate of DRP. METHODS:Prospective randomized controlled inte...

    journal_title:African health sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.4314/ahs.v14i3.7

    authors: Gangwar SS,Monisha N,Nachiya J,Narasingarao K,Parimalakrishnan S,Singh SP

    更新日期:2014-09-01 00:00:00

  • Adverse drug reactions in patients admitted on internal medicine wards in a district and regional hospital in Uganda.

    abstract:INTRODUCTION:The burden of both community and hospital acquired adverse drug reactions (ADRs) are some of the important issues in pharmacotherapy. At the time of this study there was very scanty literature in this area from Africa. OBJECTIVE:This study was done to determine the frequency and characteristics of ADRs in...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Tumwikirize WA,Ogwal-Okeng JW,Vernby A,Anokbonggo WW,Gustafsson LL,Lundborg SC

    更新日期:2011-03-01 00:00:00

  • Lassa fever - full recovery without ribavarin treatment: a case report.

    abstract:BACKGROUND:Lassa fever is a rodent-borne zoonosis that clinically manifests as an acute hemorrhagic fever. It is treated using ribavarin. Surviving Lassa fever without receiving the antiviral drug ribavarin is rare. Only few cases have been documented to date. CASE PRESENTATION:We report a case of a 59-year old female...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v14i4.40

    authors: Ajayi NA,Ukwaja KN,Ifebunandu NA,Nnabu R,Onwe FI,Asogun DA

    更新日期:2014-12-01 00:00:00

  • Echocardiographic pattern and severity of valve dysfunction in children with rheumatic heart disease seen at Uganda Heart Institute, Mulago hospital.

    abstract:BACKGROUND:Rheumatic heart disease (RHD) is the commonest acquired heart disease in children worldwide but in Uganda, data is scarce regarding its morbidity and mortality. The disease has a progressive course and patients usually require valve repair/replacement in the future. OBJECTIVES:To describe the frequency of e...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v14i3.17

    authors: Lubega S,Aliku T,Lwabi P

    更新日期:2014-09-01 00:00:00

  • Traditional herbal remedies used in the management of sexual impotence and erectile dysfunction in western Uganda.

    abstract:BACKGROUND:The utilisation of ethnobotanical indigenous knowledge is vital in male sexual reproductive health care delivery in western Uganda. Reproductive health care is the second most prevalent health care problem in Africa. However, this concept of reproductive health care has been focusing mainly on women disregar...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Kamatenesi-Mugisha M,Oryem-Origa H

    更新日期:2005-03-01 00:00:00

  • Prevalence of intestinal parasitic infections among HIV/AIDS patients from two health institutions in Abuja, Nigeria.

    abstract:BACKGROUND:Intestinal parasitic infections play a vital role in the prognosis of HIV/AIDS in patients. OBJECTIVES:The aim of this study was to determine the prevalence of intestinal parasitic infections (IPIs) in HIV-infected individuals in two health facilities in Abuja-Nigeria. METHODS:A cross sectional study was c...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v11i3.70066

    authors: Abaver DT,Nwobegahay JM,Goon DT,Iweriebor BC,Anye DN

    更新日期:2011-08-01 00:00:00

  • Potential of household environmental resources and practices in eliminating residual malaria transmission: a case study of Tanzania, Burundi, Malawi and Liberia.

    abstract:BACKGROUND:The increasing protection gaps of insecticide-treated nets and indoor-residual spraying methods against malaria have led to an emergence of residual transmission in sub-Saharan Africa and thus, supplementary strategies to control mosquitoes are urgently required. OBJECTIVE:To assess household environmental ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v15i3.16

    authors: Semakula HM,Song G,Zhang S,Achuu SP

    更新日期:2015-09-01 00:00:00

  • A case report: the first successful cochlear implant in Uganda.

    abstract::Hearing impairment is a significant disability. According to the World Health Organization (WHO), more than 80% of the world's approximately 120 million people with hearing impairment live in developing countries. Cochlear implant is the only therapeutic intervention for those with severe-profound sensorineural hearin...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v15i4.38

    authors: Byaruhanga R,Roland JT Jr,Buname G,Kakande E,Awubwa M,Ndorelire C,Namwagala J

    更新日期:2015-12-01 00:00:00

  • Maternal nutrition: how is Eastern and Southern Africa faring and what needs to be done?

    abstract:BACKGROUND:The progress in key maternal health indicators in the Eastern and Southern Africa Region (ESAR) over the past two decades has been slow. OBJECTIVE:This paper analyzed available information on nutrition programs and nutrition-specific interventions targeting maternal nutrition in the ESAR and proposes steps ...

    journal_title:African health sciences

    pub_type: 杂志文章,meta分析

    doi:10.4314/ahs.v15i2.28

    authors: Salam RA,Syed B,Syed S,Das JK,Zagre NM,Rayco-Solon P,Bhutta ZA

    更新日期:2015-06-01 00:00:00

  • MicroRNA expression profiling in human acute organophosphorus poisoning and functional analysis of dysregulated miRNAs.

    abstract:Objective:Acute organophosphorus(OP) pesticide poisoning is associated with dysfunctions in multiple organs, especially skeletal muscles, the nervous system and the heart. However, little is known about the specific microRNA (miRNA) changes that control the pathophysiological processes of acute OP poisoning damage. We ...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:10.4314/ahs.v18i2.18

    authors: Yuan H,Yuan M,Tang Y,Wang B,Zhan X

    更新日期:2018-06-01 00:00:00

  • Effect of removal of AuraOnce™ laryngeal mask in awake or deep anaesthesia: a randomized controlled trial.

    abstract:Background:The manufacturer Ambu® recommends that the AuraOnce™ laryngeal mask be removed once the patient is fully awake. Studies have shown benefit in removal of the laryngeal mask airway while a patient is deeply anaesthetized. Current evidence is inconclusive, as to which approach is preferable and safer in adults....

    journal_title:African health sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.4314/ahs.v19i4.16

    authors: Ombaka R,Mung'ayi V,Nekyon D,Mir S

    更新日期:2019-12-01 00:00:00

  • Factors affecting quality of life in cancer patients undergoing chemotherapy.

    abstract:BACKGROUND:Cancer can produce many different symptoms, some subtle and some not at all subtle. An increasingly important issue in oncology is to evaluate quality of life (QoL) in cancer patients. The cancer-specific QoL is related to all stages of this disease. OBJECTIVE:The aim of this study was to evaluate the QoL i...

    journal_title:African health sciences

    pub_type: 杂志文章

    doi:

    authors: Heydarnejad MS,Hassanpour DA,Solati DK

    更新日期:2011-06-01 00:00:00