Biotransformation of 20(S)-protopanaxatriol by Mucor spinosus and the cytotoxic structure activity relationships of the transformed products.

abstract：:As part of a project to characterise plant-derived natural products that modulate bacterial multidrug resistance (MDR), bioassay-guided fractionation of a chloroform extract of the aerial parts of Rosmarinus officinalis led to the characterisation of the known abietane diterpenes carnosic acid (1), carnosol (2) and 12...

journal_title：Phytochemistry

authors： Oluwatuyi M,Kaatz GW,Gibbons S

更新日期：2004-12-01 00:00:00

abstract：:The CH(2)Cl(2) extract of aerial parts of Eupatorium perfoliatum L. exhibits antiprotozoal activity under in vitro conditions, especially against Plasmodium falciparum (IC(50)=2.7μg/ml). The search for active compounds yielded seven sesquiterpene lactones: Four structurally similar guaianolides, one dimeric guaianolid...

journal_title：Phytochemistry

authors： Maas M,Hensel A,Costa FB,Brun R,Kaiser M,Schmidt TJ

更新日期：2011-05-01 00:00:00

abstract：:Profiles of terpenoid glycoside metabolites in glandular trichomes of Solanum habrochaites LA1777 leaves were generated using ultrahigh performance liquid chromatography/time-of-flight mass spectrometry with multiplexing of non-selective collision-induced dissociation (CID). Profiling data suggested a diverse group of...

journal_title：Phytochemistry

authors： Ekanayaka EA,Li C,Jones AD

更新日期：2014-02-01 00:00:00

abstract：:Strychnos nux-vomica L. (Loganiaceae) is famous for its monomeric alkaloid content, such as strychnine, a convulsant poison. The stem bark of the tree is traditionally used to treat intermittent fever in South East Asia. In various studies, it appeared that dimeric indolo-monoterpenic alkaloids possess a promising act...

journal_title：Phytochemistry

authors： Jonville MC,Dive G,Angenot L,Bero J,Tits M,Ollivier E,Frédérich M

更新日期：2013-03-01 00:00:00

abstract：:In order to determine how plant uptake of a sulfur-rich secondary metabolite, sinalbin, affects the metabolic profile of sulfur-deficient plants, gas chromatography time-of-flight mass spectrometry (GC-TOF-MS), in combination with liquid chromatography-mass spectrometry (LC-MS), was used to survey the metabolome of Ar...

journal_title：Phytochemistry

authors： Zhang J,Sun X,Zhang Z,Ni Y,Zhang Q,Liang X,Xiao H,Chen J,Tokuhisa JG

更新日期：2011-10-01 00:00:00

abstract：:Seven pyranocoumarins, clauemarmarins A-G, along with 6 known analogues were isolated from the stems of Clausena emarginata. Their structures were elucidated by extensive spectroscopic analyses, and the absolute stereochemistries at C-6″ of clauemarmarin B, C and D and the absolute configurations of clauemarmarin E, F...

journal_title：Phytochemistry

authors： Xia HM,Li CJ,Yang JZ,Ma J,Li Y,Li L,Zhang DM

更新日期：2016-10-01 00:00:00

abstract：:Four cycloartane- (hareftosides A-D) and oleanane-type triterpenoids (hareftoside E) were isolated from Astragalus hareftae along with fifteen known compounds. Structures of the compounds were established as 3,6-di-O-β-D-xylopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane, 3,6,24-tri-O-β-D-xylopyranosyl-3β,6α,16β...

journal_title：Phytochemistry

authors： Horo I,Bedir E,Masullo M,Piacente S,Ozgökçe F,Alankuş-Çalışkan O

更新日期：2012-12-01 00:00:00

abstract：:Four new ent-labdane diterpenes were isolated from the freshwater aquatic plant Potamogeton pectinatus, together with two known furano-ent-labdanes. The new compounds were assigned the structures methyl-15,16-epoxy-12(R)-acetoxy- 8(17), 13(16),14-ent-labdatrien-19-oate,15,16-epoxy-12(R)-acetoxy-8(17), 13(16),14-ent-la...

journal_title：Phytochemistry

authors： Waridel P,Wolfender JL,Lachavanne JB,Hostettmann K

更新日期：2003-12-01 00:00:00

abstract：:The effects of exogenous silicon (Si) on plant growth, activities of superoxide dismutase (SOD), guaiacol peroxidase (GPX), ascorbate peroxidase (APX), dehydroascorbate reductase (DHAR), glutathione reductase (GR) and catalase, and concentrations of ascorbate and glutathione were investigated in cucumber (Cucumis sati...

journal_title：Phytochemistry

authors： Shi Q,Bao Z,Zhu Z,He Y,Qian Q,Yu J

更新日期：2005-07-01 00:00:00

abstract：:The role played by molecules of the strigolactone family in stimulating the germination of seeds of parasitic weeds of the genera Striga, Orobanche and Alectra has never been clearly elucidated. The biogenesis of these unusual terpenoid lactones, originally identified in minute quantities in the root exudates of a sma...

journal_title：Phytochemistry

authors： Humphrey AJ,Beale MH

更新日期：2006-04-01 00:00:00

abstract：:A novel pyradine-derivative was isolated from the mushroom Albatrellus confluens. This compound promoted melanin synthesis by B16 melanoma cells. ...

journal_title：Phytochemistry

authors： Kawagishi H,Tanaka A,Sugiyama K,Mori H,Sakamoto H,Ishiguro Y,Kobayashi K,Uramato M

更新日期：1996-05-01 00:00:00

abstract：:Glucosinolates are secondary plant compounds typically found in members of the Brassicaceae and a few other plant families. Usually each plant species contains a specific subset of the ∼ 130 different glucosinolates identified to date. However, intraspecific variation in glucosinolate profiles is commonly found. Sinal...

journal_title：Phytochemistry

authors： de Graaf RM,Krosse S,Swolfs AE,te Brinke E,Prill N,Leimu R,van Galen PM,Wang Y,Aarts MG,van Dam NM

更新日期：2015-02-01 00:00:00

abstract：:Two novel styrl-pyrones, (+)-garvensintriol and (+)-etharvendiol, together with a known cytotoxic furano-furone, (+)-goniofufurone, have been isolated from the stem bark of Goniothalamus arvensis. A different relative configuration, cis-erythro-erythro for garvensintriol and cis-threo-erythro for etharvendiol, is esta...

journal_title：Phytochemistry

authors： Bermejo A,Blázquez MA,Rao KS,Cortes D

更新日期：1998-04-01 00:00:00

abstract：:A broad-based characterisation of a pharmacologically active dichloromethane extract from Isatis tinctoria leaves was carried out. For a comprehensive picture we also included the polar constituents of I. tinctoria (MeOH extract) and for comparative purposes, the taxonomically closely related plant I. indigotica. Diod...

journal_title：Phytochemistry

authors： Mohn T,Plitzko I,Hamburger M

更新日期：2009-05-01 00:00:00

abstract：:Chemical systematics sets out to interpret the phylogenetic implications of the occurrence and distribution of secondary metabolites. In this review, a number of the major contributions from the 1960's and 1970's are identified and re-assessed in the light of recent evidence gained from DNA studies. It is shown that f...

journal_title：Phytochemistry

authors： Waterman PG

更新日期：2007-11-01 00:00:00

abstract：:A series of 3α,5-cycloandrostane analogues with a range of functionality (6α and 6β alcohols and ketone) at carbon 6 were tested in the endogenous lactonization pathway in Aspergillus tamarii KITA. This metabolic route converts progesterone to testololactone in high yield through a four step enzymatic pathway. To date...

journal_title：Phytochemistry

authors： Hunter AC,Patel S,Dedi C,Dodd HT,Bryce RA

更新日期：2015-11-01 00:00:00

abstract：:The patterns of secondary metabolites in leaves of yeast invertase-transgenic tobacco plants (Nicotiana tabacum L. cv. Samsun NN) were analyzed. Plants expressing cytosolic yeast-derived invertase (cytInv) or apoplastic (cell wall associated) yeast invertase (cwInv) showed a characteristic phytochemical phenotype comp...

journal_title：Phytochemistry

authors： Baumert A,Mock HP,Schmidt J,Herbers K,Sonnewald U,Strack D

更新日期：2001-03-01 00:00:00

abstract：:The fatty acid compositions of 22 species of marine macrophytes, belonging to the Ceramiales, Cryptonemiales, Nemalionales, Laminariales, Chordariales, Scytosiphonales, Desmarestiales, Dictyosiphonales, Fucales, Dictyotales and Ulvales and collected from the Bohai Sea, were determined by capillary gas chromatography. ...

journal_title：Phytochemistry

authors： Li X,Fan X,Han L,Lou Q

更新日期：2002-01-01 00:00:00

abstract：:Six new steroidal saponins have been isolated from the fresh bulbs of Camassia cusickii. Their structures were determined by spectroscopic analysis and some chemical transformations to be (25R)-5 alpha-spirostan-3 beta,6 alpha-diol (chlorogenin) 6-O-beta-D-glucopyranoside, chlorogenin 6-O-beta-D-glucopyranosyl-(1----2...

journal_title：Phytochemistry

authors： Mimaki Y,Sashida Y,Kawashima K

更新日期：1991-01-01 00:00:00

abstract：:Psiadia arguta (Asteraceae) is endemic to the island of Mauritius in the Indian Ocean. The species is traditionally used to treat various ailments, such as its use as an expectorant or for the treatment of bronchitis and asthma. Preliminary biological screenings have displayed the antimalarial (Plasmodium falciparum) ...

journal_title：Phytochemistry

authors： Mahadeo K,Grondin I,Herbette G,Palama TL,Bouchemal N,Soulange J,Laulloo SJ,Sadeyen J,Humeau L,Frederich M,Gauvin-Bialecki A,Kodja H

更新日期：2020-08-01 00:00:00

abstract：:Nine cycloartane triterpenoids, including two new derivatives 22,25-dihydroxy-cycloart-23E-en-3-one and 24-methylenecycloartane-3 beta,22-diol have been isolated from leaves of Guarea macrophylla. The structures were elucidated by interpretation of spectral data, mainly 1H and 13C NMR, including bidimensional analysis...

journal_title：Phytochemistry

authors： Lago JH,Roque NF

更新日期：2002-06-01 00:00:00

abstract：:Six compounds from the aerial parts of the Argentinean plant Hymenoxys robusta (Rusby) Parker were isolated and their structures elucidated using extensive spectroscopic analyses. These compounds comprise two inositol derivatives and four 3,4-seco-pseudoguaianolides, including vermeerin. Bioactivity assays of these co...

journal_title：Phytochemistry

authors： Fortuna AM,Juárez ZN,Bach H,Nematallah A,Av-Gay Y,Sánchez-Arreola E,Catalán CA,Turbay S,Hernández LR

更新日期：2011-12-01 00:00:00

abstract：:The tetrahydroanthraquinones (1S,3S)-austrocortilutein (4) and (1S,3S)-austrocortirubin (7) are octaketides formed in the fruit bodies of the fungus Dermocybe splendida via the gentiobioside 2 of the dihydroanthracenone (S)-torosachrysone (1). ...

journal_title：Phytochemistry

authors： Elsworth C,Gill M,Saubern S

更新日期：2000-09-01 00:00:00

abstract：:Six acylated delphinidin glycosides (pigments 1-6) and one acylated kaempferol glycoside (pigment 9) were isolated from the blue flowers of cape stock (Heliophila coronopifolia) in Brassicaceae along with two known acylated cyanidin glycosides (pigments 7 and 8). Pigments 1-8, based on 3-sambubioside-5-glucosides of d...

journal_title：Phytochemistry

authors： Saito N,Tatsuzawa F,Toki K,Shinoda K,Shigihara A,Honda T

更新日期：2011-12-01 00:00:00

abstract：:Fractionation of an HIV-inhibitory organic extract of Geniostoma antherotrichum afforded a glycoside derivative, which has been characterized as 2-hydroxy-3-O-beta-D-glucopyranosyl-benzoic acid (1) on the basis of spectral analyses. The HIV-inhibitory activity of the extract was traced to polymeric tannins, while 1 wa...

journal_title：Phytochemistry

authors： Rashid MA,Gustafson KR,Cardellina JH 2nd,Boyd MR

更新日期：1996-03-01 00:00:00

abstract：:A protein phosphatase (WbPP) has been purified from the soluble fraction of the winged bean (Psophocarpus tetragonolobus) shoot extract. The preparation is essentially homogenous as shown by the constant specific activity of the enzyme across the peak fractions, eluted from the thiophosphorylated histone-Sepharose aff...

journal_title：Phytochemistry

authors： Ganguly S,Singh M

更新日期：1999-09-01 00:00:00

abstract：:The influence of solar irradiance and seasons on prostaglandin (PG) and arachidonic acid (AA) content in the marine red alga Gracilaria verrucosa (Huds.) Papenf. (unattached form) was investigated. PGA(2), PGE(2), PGF(2), and 15-keto-PGE(2) were isolated from the alga, quantitatively analyzed as 4-methyl-7-methoxycoum...

journal_title：Phytochemistry

authors： Imbs AB,Vologodskaya AV,Nevshupova NV,Khotimchenko SV,Titlyanov EA

更新日期：2001-12-01 00:00:00

abstract：:Green tissues of spikemoss Selaginella martensii Spring possessed the complex oxylipins patterns. Major oxylipins were the products of linoleic and α-linolenic acids metabolism via the sequential action of 13-lipoxygenase and divinyl ether synthase (DES) or allene oxide synthase (AOS). AOS products were represented by...

journal_title：Phytochemistry

authors： Ogorodnikova AV,Mukhitova FK,Grechkin AN

更新日期：2015-10-01 00:00:00

abstract：:In addition to lotaustralin and linamarin, a novel cyanogenic glycoside, 2-((6-O-(beta-D-apiofuranosyl)-beta-D-glucopyranosyl)oxy)-2-met hylbutanenitrile , two novel non-cyanogenic glycosides, (2S)-((6-O-(beta-D-apiofuranosyl)-beta-D- glucopyranosyl)oxy)butane and 2-((6-O-(beta-D-apiofuranosyl)-beta-D-glucopyranosyl)o...

journal_title：Phytochemistry

authors： Prawat H,Mahidol C,Ruchirawat S,Prawat U,Tuntiwachwut-tikul P,Tooptakong U,Taylor WC,Pakawatchai C,Skeleton BW,White AH

更新日期：1995-11-01 00:00:00

abstract：:Triterpenoid saponins, impatienosides A-G, together with 12 known saponins, were isolated from the whole plants of Impatiens siculifer. Their structures were established on the basis of extensive 1D and 2D NMR and MS analyses coupled with chemical degradation. Cytotoxic activities of the isolated saponins were evaluat...

journal_title：Phytochemistry

authors： Li W,Bi X,Wang K,Li D,Satou T,Koike K

更新日期：2009-04-01 00:00:00