Antimicrobial activities of sesquiterpene lactones and inositol derivatives from Hymenoxys robusta.

Abstract:

:Six compounds from the aerial parts of the Argentinean plant Hymenoxys robusta (Rusby) Parker were isolated and their structures elucidated using extensive spectroscopic analyses. These compounds comprise two inositol derivatives and four 3,4-seco-pseudoguaianolides, including vermeerin. Bioactivity assays of these compounds against bacterial and fungal pathogens showed that only vermeerin possessed antimicrobial activity specific against Staphylococcus aureus, and showed no toxicity when exposed to human-derived macrophages.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Fortuna AM,Juárez ZN,Bach H,Nematallah A,Av-Gay Y,Sánchez-Arreola E,Catalán CA,Turbay S,Hernández LR

doi

10.1016/j.phytochem.2011.09.001

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

2413-8

issue

18

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(11)00413-4

journal_volume

72

pub_type

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