T-cell subsets in patients with preeclampsia.

Abstract:

:Peripheral blood mononuclear cells from patients with preeclampsia were enumerated by means of monoclonal anti-T-cell antibodies. The percentage of total T cells was significantly decreased in this group of patients, as compared with normal term pregnant women. The low proportion of T cells was due to a proportional reduction in both helper and suppressor T cells; therefore, the ratio of helper to suppressor T cells was not different from that in normal pregnant women. There was no correlation between the degree of reduction in percentage of T cells and severity of the disease. The absolute numbers of T cells were slightly, but not significantly, decreased. Our findings support previous evidence of reduced, not increased, immune reactivity in preeclampsia.

journal_name

Am J Obstet Gynecol

authors

Sridama V,Yang SL,Moawad A,DeGroot LJ

doi

10.1016/0002-9378(83)90018-2

subject

Has Abstract

pub_date

1983-11-01 00:00:00

pages

566-9

issue

5

eissn

0002-9378

issn

1097-6868

pii

0002-9378(83)90018-2

journal_volume

147

pub_type

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