当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Pregnancy outcome for women with very low levels of maternal serum unconjugated estriol on second-trimester screening.

Pregnancy outcome for women with very low levels of maternal serum unconjugated estriol on second-trimester screening.

Abstract：

OBJECTIVE:Our purpose was to assess pregnancy outcome for women whose second-trimester triple screen results revealed very low unconjugated estriol levels. STUDY DESIGN:Of 44,146 women screened for alpha-fetoprotein, human chorionic gonadotropin, and unconjugated estriol, a group of women with isolated very low unconjugated estriol levels were selected as the study group. Pregnancy outcome was obtained by contacting the referring physicians. RESULTS:During the study period 62 women had unconjugated estriol levels at or below the sensitivity of the assay. Fetal death was the most common explanation, accounting for 37.1% of cases. Six cases of early death followed uneventful prenatal visits. Eighteen women had unexplained very low unconjugated estriol levels. Of these 18, four cases of placental sulfatase deficiency were diagnosed. Sixteen of these 18 women gave birth to male infants (p = 0.03). CONCLUSION:A very low unconjugated estriol level in the second trimester is associated with increased risk for early death and placental sulfatase deficiency.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Schleifer RA,Bradley LA,Richards DS,Ponting NR

doi

10.1016/0002-9378(95)91343-2

subject

Has Abstract

pub_date

1995-10-01 00:00:00

pages

1152-6

issue

4

eissn

0002-9378

issn

1097-6868

pii

0002-9378(95)91343-2

journal_volume

173

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • Incidence and management of abdominal sacrocolpopexy mesh erosions.

    abstract：OBJECTIVE:This study was undertaken to evaluate the occurrence and management of mesh erosions in patients undergoing abdominal sacrocolpopexy. STUDY DESIGN:A retrospective chart review of the abdominal sacrocolpopexy procedure (n = 92) between 1997 and 2003 was performed. Patients with mesh erosion were identified. I...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2005.02.062

    authors： Begley JS,Kupferman SP,Kuznetsov DD,Kobashi KC,Govier FE,McGonigle KF,Muntz HG

    更新日期：2005-06-01 00:00:00

  • Quality of life after the menopause: influence of hormonal replacement therapy.

    abstract：OBJECTIVE:Our purpose was to demonstrate the clinical efficacy and effect of hormone replacement therapy in menopause on quality of life. STUDY DESIGN:A randomized, open, 6-month comparison of hormone replacement therapy (estradiol transdermal system [Estraderm TTS] plus chlormadinone) and symptomatic treatment (verap...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0002-9378(94)70239-x

    authors： Limouzin-Lamothe MA,Mairon N,Joyce CR,Le Gal M

    更新日期：1994-02-01 00:00:00

  • Emergent cesarean delivery in patients undergoing a trial of labor with a transverse lower-segment scar.

    abstract：:The American College of Obstetricians and Gynecologists recommends that women with previous low transverse cesarean sections who are candidates for a trial of labor should undergo such a trial only in a special environment. Such recommendations imply that these women are at greater risk than the general population for...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(86)90321-2

    authors： Finley BE,Gibbs CE

    更新日期：1986-11-01 00:00:00

  • The uterine contractility index: a research and diagnostic tool in dysmenorrhea.

    abstract：:Women who experienced severe primary dysmenorrhea had 90 to 120 minutes of continuous uterine pressure monitoring during their peak period of discomfort. During the initial screening cycle, they were given 40 mg of piroxicam, a nonsteroidal anti-inflammatory drug which inhibits prostaglandin synthesis. The pressure tr...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章

    doi：10.1016/0002-9378(83)90865-7

    authors： Schulman H,Duvivier R,Blattner P

    更新日期：1983-04-15 00:00:00

  • Transient umbilical cord occlusion causes hippocampal damage in the fetal sheep.

    abstract：OBJECTIVE:The purpose of our study was to examine the neuronal outcome after a standardized period of umbilical cord occlusion. STUDY DESIGN:The umbilical cord was clamped for 10 minutes in nine experimental and four control chronically instrumented fetal sheep. Three days later the animals were killed for histologic ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)91728-1

    authors： Mallard EC,Gunn AJ,Williams CE,Johnston BM,Gluckman PD

    更新日期：1992-11-01 00:00:00

  • Cost minimization analysis of laparoscopic sacral colpopexy and total vaginal mesh.

    abstract：OBJECTIVE:The objective of the study was a cost minimization analysis of the laparoscopic sacral colpopexy (LSC) and total vaginal mesh (TVM). STUDY DESIGN:Primary clinical costs were derived from our randomized control trial comparing LSC and TVM and were compared using prices from privately- and publicly-conducted p...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ajog.2011.12.012

    authors： Maher CF,Connelly LB

    更新日期：2012-05-01 00:00:00

  • Fetal movements in multiple pregnancy.

    abstract：:Fetal activity in multiple pregnancies, as expressed by maternal daily fetal movement recordings, was compared with that in singleton pregnancies. It was found that the mean fetal activity in 33 cases of twins, six cases of triplets, one case of quadruplets, and one case of quintuplets was generally higher than that o...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(83)91079-7

    authors： Samueloff A,Evron S,Sadovsky E

    更新日期：1983-08-01 00:00:00

  • Clear cell carcinoma arising in the abdominal wall: two case reports and literature review.

    abstract：:Clear cell carcinoma originating in the abdominal wall is rare and usually develops within endometriotic implants in the scar. We describe 2 patients: a 42 year old with a 15 cm mass on the abdominal wall treated with neoadjuvant chemotherapy and excision and a 51 year old with a 6 cm abdominal mass treated with excis...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ajog.2012.05.029

    authors： Mert I,Semaan A,Kim S,Ali-Fehmi R,Morris RT

    更新日期：2012-08-01 00:00:00

  • The role of adjuvant therapy in Stage I ovarian cancer.

    abstract：:Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-9378(80)90024-1

    authors： Hreshchyshyn MM,Park RC,Blessing JA,Norris HJ,Levy D,Lagasse LD,Creasman WT

    更新日期：1980-09-15 00:00:00

  • Joseph Price oration. The multiple gestation epidemic: the role of the assisted reproductive technologies.

    abstract：:Human IVF has transformed so many lives, but there has been one major drawback--namely the so-called epidemic of multiple gestations. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type：

    doi：10.1016/j.ajog.2004.02.017

    authors： Templeton A

    更新日期：2004-04-01 00:00:00

  • Quantitative assessment of Langerhans' cells in human cervical intraepithelial neoplasia and wart virus infection.

    abstract：:Langerhans' cell density was assessed quantitatively in cervical wart virus infection (cervical condyloma), cervical intraepithelial neoplasia, and koilocytic dysplasia with use of an antibody to S100 protein and an indirect immunoperoxidase technique. When compared with normal ectocervix, Langerhans' cell density was...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(86)90592-2

    authors： McArdle JP,Muller HK

    更新日期：1986-03-01 00:00:00

  • Effects of inhibition of prostaglandin synthesis on flow and composition of fetal urine, lung liquid, and swallowed fluid in sheep.

    abstract：OBJECTIVE:Our aim was to determine the effects of blocking prostaglandin synthesis, by infusion of indomethacin into the fetal circulation, on factors regulating amniotic fluid volume and on plasma composition in the mother and fetus. STUDY DESIGN:Indomethacin was administered to fetal sheep during 8 hours at 124.0 +/...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(94)70406-6

    authors： Wlodek ME,Harding R,Thorburn GD

    更新日期：1994-01-01 00:00:00

  • Danazol: endocrine pharmacology and therapeutic applications.

    abstract：:The options for the medical management of endometriosis have been expanded by the introduction of the synthetic steroid, danazol. The results of large clinical studies suggest that danazol treatment produces significant improvement in the symptoms, signs, and laparoscopic findings of endometriosis. The original studie...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/0002-9378(81)90611-6

    authors： Barbieri RL,Ryan KJ

    更新日期：1981-10-15 00:00:00

  • Evaluation of the fetal assessment score in pregnancies at risk for intrauterine hypoxia.

    abstract：OBJECTIVE:Our purpose was to define the diagnostic value of a new fetal assessment score that is based on each of the components of the Apgar score. STUDY DESIGN:A fetal assessment score was established to study the main fetal vital functions: (1) cardiovascular (heart rate, color of the skin in the Apgar score), now ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(93)90618-s

    authors： Arabin B,Snyjders R,Mohnhaupt A,Ragosch V,Nicolaides K

    更新日期：1993-09-01 00:00:00

  • Cystine animopeptidase and leucine aminopeptidase of choriocarcinoma cells grown in culture.

    abstract：:Cystine animopeptidase (CAP) and leucine aminopeptidase (LAP) in choriocarcinoma cells grown in culture were assayed and characterized electrophoretically. The specific activity of CAP in choriocarcinoma was about 1.5-fold greater than the specific activity of term placenta. The extract of choriocarcinoma contained an...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(75)90574-8

    authors： Ota T,Chen CH,Robinson JC

    更新日期：1975-07-15 00:00:00

  • Cost-effective delivery management of the vertex and nonvertex twin gestation.

    abstract：OBJECTIVE:The aim of the study was to determine the most cost-effective delivery management of vertex and nonvertex twin pair gestations. STUDY DESIGN:Two hundred sixty-six consecutive twin gestations were followed up prospectively in a special antepartum Twins Clinic directed by the Maternal-Fetal Medicine Division. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(98)70179-6

    authors： Mauldin JG,Newman RB,Mauldin PD

    更新日期：1998-10-01 00:00:00

  • Effects of cochlear ablation on local cerebral glucose utilization in fetal sheep.

    abstract：:Local cerebral glucose utilization was measured by the [14C]-deoxyglucose method in five near-term fetal sheep in whom bilateral ablation of the cochleae had been accomplished aseptically 5 to 8 days earlier. The tympanic membrane and ossicles were removed and all turns of each cochlea were unroofed with destruction c...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(87)80240-5

    authors： Abrams RM,Hutchison AA,McTiernan MJ,Merwin GE

    更新日期：1987-12-01 00:00:00

  • Defining the relationship between obstetricians and maternal-fetal medicine specialists.

    abstract：OBJECTIVE:The purpose of this study was to determine how frequently general obstetricians refer pregnant patients to maternal-fetal medicine specialists in the presence of the clinical indications specified as appropriate for referral or consultation by the 1996 statement of the Society of Perinatal Obstetricians. STU...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2001.117348

    authors： Vintzileos AM,Ananth CV,Smulian JC,Scorza WE,Knuppel RA

    更新日期：2001-10-01 00:00:00

  • Neonatal outcomes in pregnancies with preeclampsia or gestational hypertension and in normotensive pregnancies that delivered at 35, 36, or 37 weeks of gestation.

    abstract：OBJECTIVE:The purpose of this study was to compare neonatal outcomes of pregnancies with preeclampsia or gestational hypertension with those of normotensive pregnancies that delivered at 35, 36, or 37 weeks of gestation separately. STUDY DESIGN:Secondary analysis of neonatal outcomes by week of delivery between 35 and...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ajog.2007.06.059

    authors： Habli M,Levine RJ,Qian C,Sibai B

    更新日期：2007-10-01 00:00:00

  • Multilocus interactions at maternal tumor necrosis factor-alpha, tumor necrosis factor receptors, interleukin-6 and interleukin-6 receptor genes predict spontaneous preterm labor in European-American women.

    abstract：OBJECTIVE:We hypothesize that genetic variations (single nucleotide polymorphisms-SNPs) in the tumor necrosis factor-alpha (TNF-alpha), TNF receptors (TNFRI and TNFRII), interleukin-6 (IL-6) and IL-6 receptor (IL-6R) genes predict high-risk status for spontaneous preterm birth (sPTB) in European-American women. In this...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2006.03.059

    authors： Menon R,Velez DR,Simhan H,Ryckman K,Jiang L,Thorsen P,Vogel I,Jacobsson B,Merialdi M,Williams SM,Fortunato SJ

    更新日期：2006-06-01 00:00:00

  • Tubal sterilization. Study at Evanston Hospital.

    abstract：:This article presents a review of 902 tubal sterilizations performed in an 18 1/2-year period at a predominantly private teaching service. 803 (89%) of the sterilizations were puerperal, generally performed within 48 hours of delivery or with cesarean section. The Pomeroy technique (often modified) was used in 97.2%...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：

    authors： McElin TW,Buckingham JC,Johnson RE

    更新日期：1967-02-15 00:00:00

  • Blunted vasoreactivity in pregnant guinea pigs is not restored by meclofenamate.

    abstract：:Pregnant women show a reduced pressor responsiveness to angiotensin II, but the mechanism responsible in unclear. We sought to determine whether reduced pressor responsiveness was due to decreased vasoreactivity and the involvement of increased vasodilator prostaglandin production in decreases observed. We found that ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(89)90132-4

    authors： Harrison GL,Moore LG

    更新日期：1989-01-01 00:00:00

  • The bladder neck support prosthesis: a nonsurgical approach to stress incontinence in adult women.

    abstract：OBJECTIVE:Our purpose was to evaluate a vaginal device designed to support the bladder neck in women with urinary stress incontinence. STUDY DESIGN:Thirty-two physically active incontinent women underwent urodynamic evaluation and maintained a bladder diary before enrollment and after 4 weeks of device use. Outcome me...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章

    doi：10.1016/0002-9378(94)90470-7

    authors： Davila GW,Ostermann KV

    更新日期：1994-07-01 00:00:00

  • Vaginal birth after cesarean among women with gestational diabetes.

    abstract：OBJECTIVE:We sought to determine the pregnancy and infant outcomes of women with gestational diabetes who attempted vaginal birth after previous cesarean delivery. STUDY DESIGN:We conducted a retrospective cohort study to compare women with gestational diabetes with matched control subjects without diabetes who attemp...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2001.115176

    authors： Coleman TL,Randall H,Graves W,Lindsay M

    更新日期：2001-05-01 00:00:00

  • A single physician's experience with four thousand six hundred genetic amniocenteses.

    abstract：OBJECTIVE:We sought to assess changes in indications, technique, successful fluid aspiration, and pregnancy outcomes in a large cohort of genetic amniocenteses performed by a single physician. STUDY DESIGN:Records were reviewed regarding 4600 women who underwent genetic amniocentesis by a single physician between 1972...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2001.116737

    authors： Horger EO 3rd,Finch H,Vincent VA

    更新日期：2001-08-01 00:00:00

  • Nighttime delivery and risk of neonatal encephalopathy.

    abstract：OBJECTIVE:The objective of the study was to determine the relationship between nighttime delivery and neonatal encephalopathy (NE). STUDY DESIGN:The design of the study was a retrospective population-based cohort of 1,864,766 newborns at a gestation of 36 weeks or longer in California, 1999-2002. We determined the ris...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2010.09.022

    authors： Wu YW,Pham TN,Danielsen B,Towner D,Smith L,Johnston SC

    更新日期：2011-01-01 00:00:00

  • Fetal fibronectin levels are elevated in maternal plasma and amniotic fluid of patients with severe preeclampsia.

    abstract：OBJECTIVE:Our purpose was to investigate levels of fetal fibronectin in maternal plasma, amniotic fluid, and umbilical cord plasma from patients with severe preeclampsia. STUDY DESIGN:The study group comprised 20 patients with severe preeclampsia (group A). An antepartum comparison group was composed of 20 healthy pat...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(95)90587-1

    authors： Kupferminc MJ,Peaceman AM,Wigton TR,Rehnberg KA,Socol ML

    更新日期：1995-02-01 00:00:00

  • Intrauterine pressure and fluid absorption during continuous flow hysteroscopy.

    abstract：OBJECTIVES:Our objectives were to document the causes of fluid absorption during continuous flow hysteroscopy and to determine under which operative conditions fluid overload may occur. STUDY DESIGN:Fifteen patients underwent operative hysteroscopy with 2% ethanol solution for uterine distention. Absorption of fluid w...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)91417-3

    authors： Vulgaropulos SP,Haley LC,Hulka JF

    更新日期：1992-08-01 00:00:00

  • Management of stage Ia1 squamous cervical cancer and the importance of excision margins: a retrospective study of long-term outcome after 25 years of follow-up.

    abstract：OBJECTIVE:The aim of this study was to assess the effect of the excision margin after cone for stage Ia1 cervical cancer on long-term outcomes. STUDY DESIGN:Retrospective observational study. Patients were divided into 3 groups. Group A underwent immediate reflex hysterectomy; group B had cervical intraepithelial neop...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2014.06.032

    authors： Papakonstantinou K,Kyrgiou M,Lyons D,Soutter WP,Ghaem-Maghami S

    更新日期：2014-12-01 00:00:00

  • The effect of progesterone on estrogen-induced uterine blood flow.

    abstract：:The effect of progesterone on estrogen-induced uterine blood flow was investigated in repeated experiments in seven nonpregnant, oophorectomized ewes with chronically implanted electromagnetic flow probes and catheters inserted into branches of the uterine arteries. Administered alone, progesterone has no effect on ba...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(77)90617-2

    authors： Resnik R,Brink GW,Plumer MH

    更新日期：1977-06-01 00:00:00