The role of adjuvant therapy in Stage I ovarian cancer.

Abstract:

:Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy.

journal_name

Am J Obstet Gynecol

authors

Hreshchyshyn MM,Park RC,Blessing JA,Norris HJ,Levy D,Lagasse LD,Creasman WT

doi

10.1016/0002-9378(80)90024-1

subject

Has Abstract

pub_date

1980-09-15 00:00:00

pages

139-45

issue

2

eissn

0002-9378

issn

1097-6868

pii

0002-9378(80)90024-1

journal_volume

138

pub_type

临床试验,杂志文章,随机对照试验
  • The effect of chronic steroid therapy on glucose tolerance in pregnancy.

    abstract::We analyzed the records of 26 pregnant patients receiving chronic steroids to assess the combined effect of pregnancy and glucocorticoid administration on glucose tolerance. Five patients (19.2%) developed diabetes mellitus, four of whom required insulin. In a pregnant control group of 1325 patients, 53 patients (4.0%...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(88)80019-x

    authors: Landy HJ,Isada NB,McGinnis J,Ratner R,Grossman JH 3rd

    更新日期:1988-09-01 00:00:00

  • Benefits, risks, costs, and patient satisfaction associated with insulin pump therapy for the pregnancy complicated by type 1 diabetes mellitus.

    abstract:OBJECTIVE:Glycemic control, perinatal outcome, and health care costs were evaluated among women with type 1 diabetes mellitus who began insulin pump therapy during pregnancy (group 1, n = 24), were treated with multiple insulin injections (group 2, n = 24), or were already using an insulin pump before pregnancy (group ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2000.106182

    authors: Gabbe SG,Holing E,Temple P,Brown ZA

    更新日期:2000-06-01 00:00:00

  • Contemporary outcomes of sickle cell disease in pregnancy.

    abstract:BACKGROUND:Data regarding pregnancy outcomes in sickle cell disease are conflicting. Previous studies are limited by small sample size, narrow geographic area, and a wide range of resource availability. OBJECTIVE:The purpose of this study was to examine the association between maternal sickle cell disease and adverse ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2016.05.032

    authors: Kuo K,Caughey AB

    更新日期:2016-10-01 00:00:00

  • Prenatal diagnosis of 47,XXX.

    abstract::We report 2 cases of 47,XXX that were diagnosed prenatally and were screened positive for trisomy 21 by biochemical and ultrasound markers. These cases underline the importance of discussing the sex chromosome abnormalities during the genetic counseling after an abnormal triple screen test or ultrasound examination. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2004.12.037

    authors: Khoury-Collado F,Wehbeh AN,Fisher AJ,Bombard AT,Weiner Z

    更新日期:2005-05-01 00:00:00

  • Functional analysis of a mutant estrogen receptor isolated from T47Dco breast cancer cells.

    abstract:OBJECTIVE:Estrogen receptor-positive cancers that initially respond to hormone therapy often progress to a resistant state. The breast cancer cell line T47Dco is a model for such resistance. It is a polymorphic line, composed of multiple cell populations that demonstrate the presence of mutant estrogen receptors by clo...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(11)90590-0

    authors: Leslie KK,Tasset DM,Horwitz KB

    更新日期:1992-04-01 00:00:00

  • Altered gene expression patterns in intrauterine growth restriction: potential role of hypoxia.

    abstract:OBJECTIVE:Placental insufficiency is a primary cause of intrauterine growth restriction (IUGR). In our study, microarray technology was used to identify genes, which may impair placentation resulting in IUGR. STUDY DESIGN:The RNA was isolated from both IUGR term placentas and normal term placentas. Microarray experime...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2006.08.027

    authors: McCarthy C,Cotter FE,McElwaine S,Twomey A,Mooney EE,Ryan F,Vaughan J

    更新日期:2007-01-01 00:00:00

  • Role of hysteroscopy in detection and extraction of endometrial polyps: results of a prospective study.

    abstract:OBJECTIVE:The aim of this study was to determine whether hysteroscopy improves the detection and extraction of endometrial polyps in postmenopausal women. This method was compared with curettage complemented by Randall polyp forceps. STUDY DESIGN:In a prospective study hysteroscopy was performed before and after curet...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2001.108332

    authors: Gebauer G,Hafner A,Siebzehnrübl E,Lang N

    更新日期:2001-01-01 00:00:00

  • Hantavirus pulmonary syndrome complicating pregnancy.

    abstract:OBJECTIVE:The purpose of this report is to bring to the attention of obstetric care providers the occurrence in pregnancy of a threatening pulmonary syndrome caused by hantavirus infection. STUDY DESIGN:Two recent cases of hantavirus pneumonitis in pregnancy, one complicated by adult respiratory distress syndrome, are...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(94)90298-4

    authors: Gilson GJ,Maciulla JA,Nevils BG,Izquierdo LE,Chatterjee MS,Curet LB

    更新日期:1994-08-01 00:00:00

  • Relationship of maternal vitamin D level with maternal and infant respiratory disease.

    abstract:OBJECTIVE:The objective of the study was to investigate the association of maternal vitamin D and maternal asthma and infant respiratory infection severity. STUDY DESIGN:The study included cross-sectional analyses of 340 mother-infant dyads enrolled from September to May 2004-2008 during an infant viral respiratory in...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2011.04.002

    authors: Carroll KN,Gebretsadik T,Larkin EK,Dupont WD,Liu Z,Van Driest S,Hartert TV

    更新日期:2011-09-01 00:00:00

  • Pretreatment of human amnion-chorion with vitamins C and E prevents hypochlorous acid-induced damage.

    abstract:OBJECTIVE:Preterm premature rupture of fetal membranes has been associated with infection, cigarette smoking, and bleeding. Hypochlorous acid (a reactive oxygen species) is central to the body's response to infection, yet it may damage surrounding tissue while destroying pathogens. We examined in vitro the tissue-damag...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2000.106676

    authors: Plessinger MA,Woods JR Jr,Miller RK

    更新日期:2000-10-01 00:00:00

  • Evaluation of multiple-marker screening for Down syndrome in a statewide population.

    abstract:OBJECTIVE:Our purpose was to evaluate our experience with a statewide, multiple-marker Down syndrome screening program. STUDY DESIGN:The results of 18,712 screening tests performed from July 1, 1991, to Oct. 31, 1992, were reviewed. Amniocentesis and aneuploidy detection rates were compared with the experience of a pr...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(93)90007-6

    authors: Wenstrom KD,Williamson RA,Grant SS,Hudson JD,Getchell JP

    更新日期:1993-10-01 00:00:00

  • The effect of low-dose 3-keto-desogestrel added to a copper-releasing intrauterine contraceptive device on menstrual blood loss: a double-blind, dose-finding, placebo-controlled study.

    abstract:OBJECTIVE:We sought to establish the lowest dose of 3-keto-desogestrel, when added to a copper-releasing intrauterine contraceptive device, that is needed to reduce menstrual blood loss to a very low level and to treat (essential) menorrhagia successfully. STUDY DESIGN:A double-blind group comparative study was design...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1067/mob.2000.104805

    authors: Janssen CA,Scholten PC,Heintz AP

    更新日期:2000-03-01 00:00:00

  • A multicenter controlled trial of fetal pulse oximetry in the intrapartum management of nonreassuring fetal heart rate patterns.

    abstract:OBJECTIVE:Recent developments permit the use of pulse oximetry to evaluate fetal oxygenation in labor. We tested the hypothesis that the addition of fetal pulse oximetry in the evaluation of abnormal fetal heart rate patterns in labor improves the accuracy of fetal assessment and allows safe reduction of cesarean deliv...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1067/mob.2000.110632

    authors: Garite TJ,Dildy GA,McNamara H,Nageotte MP,Boehm FH,Dellinger EH,Knuppel RA,Porreco RP,Miller HS,Sunderji S,Varner MW,Swedlow DB

    更新日期:2000-11-01 00:00:00

  • Successful pregnancy outcomes after amniotic fluid embolism.

    abstract::Two patients who survived cardiorespiratory arrest occurring in association with amniotic fluid embolism syndrome were seen during the subsequent pregnancy. Both had uneventful pregnancies and delivered at term without complications. These are the only case reports of pregnancy after amniotic fluid embolism, and they ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(11)91442-2

    authors: Clark SL

    更新日期:1992-08-01 00:00:00

  • Preterm twins: what threshold of birth weight discordance heralds major adverse neonatal outcome?

    abstract:OBJECTIVE:This study was undertaken to establish the optimal threshold of birth weight discordance for prediction of adverse outcome in liveborn, non-malformed preterm twins. STUDY DESIGN:We accessed a cohort of twin gestations for the period 1990 through 2000 delivered at less than 37.0 weeks' gestation. Adverse neon...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2004.05.053

    authors: Vergani P,Locatelli A,Ratti M,Scian A,Pozzi E,Pezzullo JC,Ghidini A

    更新日期:2004-10-01 00:00:00

  • Platelets and uric acid in the prediction of preeclampsia.

    abstract::Fifty-four pregnancies that were subsequently complicated by preeclampsia had platelet parameters and uric acid levels measured during pregnancy. The expected fall in platelet count and rise in platelet volume parameters and uric acid levels beyond those that occur in normal pregnancy were seen only in the week before...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(85)90555-1

    authors: Fay RA,Bromham DR,Brooks JA,Gebski VJ

    更新日期:1985-08-15 00:00:00

  • Specific systemic antioxidant response to preeclampsia in late pregnancy: the study of intracellular glutathione peroxidases in maternal and fetal blood.

    abstract:OBJECTIVE:The physiopathology of preeclampsia is still unclear, but an imbalance between reactive oxygen species (ROS) and antioxidants, also called oxidative stress, appears to be an important contributing factor. The ROS promote lipid oxidation and are known to induce stress proteins, such as hemeoxygenase 1 (HO-1) a...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2008.12.031

    authors: Boutet M,Roland L,Thomas N,Bilodeau JF

    更新日期:2009-05-01 00:00:00

  • Removal of an intra-abdominal intrauterine contraceptive device through a peritoneoscope with the use of intraoperative fluoroscopy to aid localization.

    abstract::This letter was written in response to the article by P.G. Brooks et al ( 113: 104, 1972) in which the use of the peritoneoscope for removal of extruded intrauterine contraceptive devices (IUCD) with fluoroscopy to aid localization was recommended. In recent experiences of the authors of this letter and of R.R. MacD...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(72)90884-8

    authors: Mountrose UE,Whitehouse WL

    更新日期:1972-12-15 00:00:00

  • A prospective trial of the fetal biophysical profile versus the nonstress test in the management of high-risk pregnancies.

    abstract::A randomized prospective trial study was developed to determine the diagnostic value of the fetal biophysical profile in relationship to the nonstress test. The diagnostic values of these tests were assessed in terms of the incidence of abnormal outcome. In addition comparisons between the positive and negative predic...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Platt LD,Walla CA,Paul RH,Trujillo ME,Loesser CV,Jacobs ND,Broussard PM

    更新日期:1985-11-15 00:00:00

  • Inhibition of premature labor: a multicenter comparison of ritodrine and ethanol.

    abstract::A randomized controlled study was carried out at three medical centers to compare the efficacy and side effects of ethanol and ritodrine in the treatment of threatened premature labor. One hundred and thirty-five patients judged to be between the twentieth and thirty-sixth week of gestation and presenting with clinic...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-9378(77)90115-6

    authors: Lauersen NH,Merkatz IR,Tejani N,Wilson KH,Roberson A,Mann LI,Fuchs F

    更新日期:1977-04-15 00:00:00

  • Synergistic effect of relaxin and progesterone on cyclic adenosine 3',5'-monophosphate levels in the rat uterus.

    abstract::Cyclic adenosine 3',5'-monophosphate is known to modulate smooth muscle contractility. Because both relaxin and progesterone have been demonstrated to affect myometrial cyclic adenosine monophosphate activity, we questioned whether the previously observed synergism of these two hormones in inhibiting uterine contracti...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(88)90564-9

    authors: Grazi RV,Goldsmith LT,Schmidt CL,Von Hagen S,Weiss G

    更新日期:1988-12-01 00:00:00

  • Placental metastasis from primary ocular melanoma: a case report.

    abstract::Ocular malignant melanoma, similar to the cutaneous variety, may metastasize to the placenta, almost always in the presence of widespread disease. The prognosis is poor, and there is a 25% risk of spread to the fetus. All women with a history of this disease should be informed of the risks when they are contemplating ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(96)70626-9

    authors: Marsh RD,Chu NM

    更新日期:1996-05-01 00:00:00

  • Oxytocin content of human fetal pituitary glands.

    abstract::Seventeen human fetal and neonatal pituitary glands were removed at necropsy, and analyzed for oxytocin content by a specific and sensitive radioimmunoassay, after homogenization in 0.4M acetic acid. Serial dilution of the pituitary extract showed parallelism with the oxytocin standard curve on the radioimmunoassay. C...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(84)90719-1

    authors: Khan-Dawood FS,Dawood MY

    更新日期:1984-02-15 00:00:00

  • The association between maternal age at first delivery and risk of obstetric trauma.

    abstract:BACKGROUND:There are a number of poor birth outcomes with advancing maternal age. Although there is some evidence of a higher risk of trauma to obstetric anal sphincter and the levator ani muscle with advancing age, findings to date are inconclusive. OBJECTIVE:The aim of this study was to assess the risk of pelvic flo...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2016.04.032

    authors: Rahmanou P,Caudwell-Hall J,Kamisan Atan I,Dietz HP

    更新日期:2016-10-01 00:00:00

  • Fetal breathing movements in response to maternal inhalation of 5% carbon dioxide.

    abstract::The effect upon fetal breathing movements (FBM) in 49 women with uncomplicated pregnancies who inhaled 5% carbon dioxide in air for 15 minutes was observed with an ADR real-time ultrasound scanner. A threefold increase in FBM occurred during the inhalation of CO2. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(80)90867-4

    authors: Ritchie JW,Lakhani K

    更新日期:1980-02-01 00:00:00

  • Oophorectomy as a risk factor for coronary heart disease.

    abstract:OBJECTIVE:The objective of the study was to examine the relationship between bilateral oophorectomy (BSO) and risk of coronary heart disease (CHD). STUDY DESIGN:We searched PubMed, EMBASE, meeting abstracts, and reference lists for studies that compared women with BSO at the time of hysterectomy with: (1) women with h...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ajog.2008.08.045

    authors: Jacoby VL,Grady D,Sawaya GF

    更新日期:2009-02-01 00:00:00

  • A new cervical perfusion method for induction of labor with prostaglandins.

    abstract::144 patients aged 18-41 were observed to study a new method of cervical perfusion of prostaglandins (PGs) to induce labor and missed abortion. 46 patients were primigravidae, 86 had a normal pregnancy, and 58 had missed abortion. Duration of gestation was 37-42 weeks, and duration of amenorrhea in case of missed abo...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90259-9

    authors: Boemi P,Reitano S,Cianci S

    更新日期:1982-10-15 00:00:00

  • Estrogen increases inducible nitric oxide synthase gene expression.

    abstract:OBJECTIVE:The goal of this study was to determine whether estrogen increases the expression of the inducible nitric oxide synthase gene. STUDY DESIGN:An inducible nitric oxide synthase fusion gene was created with its promoter and the reporter gene, luciferase. COS cells were transfected transiently with the fusion ge...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2003.350

    authors: Walsh LS,Ollendorff A,Mershon JL

    更新日期:2003-05-01 00:00:00

  • Cardiovascular risk and combined oral contraceptives: clinical decisions in settings of uncertainty.

    abstract::Although generally safe, combined oral contraceptives (COCs) are associated with risks, including an estimated 2-fold increased relative risk of cardiovascular events. For most women taking COCs for contraception, absolute cardiovascular risks are very low, and the overall risks of COCs are outweighed by the risks of ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2012.01.037

    authors: Beller JP,McCartney CR

    更新日期:2013-01-01 00:00:00

  • Risk factors for early death among extremely low-birth-weight infants.

    abstract:OBJECTIVE:The purposes of this study were to compare the clinical characteristics of extremely low birth-weight infants (501-1000 g birth weight) who die early (<12 hours of age) with those of infants who die >12 hours after birth and infants who survive to neonatal intensive care unit discharge and to develop a model ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2002.121652

    authors: Shankaran S,Fanaroff AA,Wright LL,Stevenson DK,Donovan EF,Ehrenkranz RA,Langer JC,Korones SB,Stoll BJ,Tyson JE,Bauer CR,Lemons JA,Oh W,Papile LA

    更新日期:2002-04-01 00:00:00