Abstract：
:A National Survey of the Oral Health of U.S. children aged 5 to 17 was conducted by the National Institute of Dental Research during the 1986-87 school year. Eleven thousand and seven adolescents aged 14 to 17 years received a periodontal assessment. Their patterns of loss of periodontal attachment as assessed by probing at mesial sites were used to classify adolescents as cases of early onset periodontitis. Approximately 0.53% of adolescents nation-wide were estimated to have localized juvenile periodontitis (LJP), 0.13% to have generalized juvenile periodontitis (GJP), and 1.61% to have incidental loss of attachment (LA) (greater than or equal to 3 mm on 1 or more teeth). The total number of adolescents affected were not trivial. Close to 70,000 adolescents in the U.S. were estimated to have LJP in 1986-87. More destructive GJP affected an estimated 17,000 adolescents. Another 212,000 adolescents were estimated to have incidental LA. Blacks were at much greater risk for all forms of early onset periodontitis than whites. Males were clearly more likely (4.3 to 1) to have GJP than females when other variables were statistically controlled. Gender associations were more complicated for LJP because gender interacted with race. Black males were 2.9 times as likely to have LJP as black females. In contrast, white females were more likely than white males to have the disease by about the same odds. When interactions among demographic variables exist, caution must be taken in comparing results from different studies.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Löe H,Brown LJdoi
10.1902/jop.1991.62.10.608subject
Has Abstractpub_date
1991-10-01 00:00:00pages
608-16issue
10eissn
0022-3492issn
1943-3670journal_volume
62pub_type
杂志文章abstract：:This study showed histopathological findings of the extracellular matrix in healthy, inflamed, and hyperplastic human gingiva with immunohistochemical techniques. The distribution of collagen types V and VI, as well as of glycoprotein fibronectin, shows that they are extracellular matrix structural components which di...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1993.64.2.110
更新日期：1993-02-01 00:00:00
abstract：BACKGROUND:Pain generated by needle sticks (Ns) for the delivery of local anesthetic and/or scaling and root planing (SRP) instrumentation is commonly addressed by the use of topical anesthetics, such as a benzocaine-gel preparation (BGP). Pain suppression following such use has been highly variable. Development of med...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1902/jop.2001.72.4.479
更新日期：2001-04-01 00:00:00
abstract：:Oral polymorphonuclear leukocytes (pmn) were obtained from 10 adult donors in good oral health using a method employing repeated mouth rinse collection. Interleukin-1β (IL-1β) mRNA was detected in freshly obtained cells by blot hybridization of total cellular RNA with a biotin labeled cDNA probe. Supernates from oral ...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1995.66.9.761
更新日期：1995-09-01 00:00:00
abstract：BACKGROUND:Microarray analysis of local and peripheral cells in subjects with immune-inflammatory diseases may identify candidate genes associated with these diseases. The present study identified differentially expressed genes in peripheral blood mononuclear cells (PBMCs) from subjects with untreated localized aggress...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2008.070309
更新日期：2008-03-01 00:00:00
abstract：:Defects in neutrophil or polymorphonuclear leukocyte (PMNL) chemotaxis have been observed in a number of clinical conditions, including Down's syndrome and insulin-dependent diabetes mellitus (IDDM), which tend to be associated with severe forms of periodontal disease. In addition, impaired PMNL chemotaxis is frequent...
journal_title：Journal of periodontology
pub_type： 杂志文章,评审
doi：10.1902/jop.1985.56.11s.56
更新日期：1985-11-01 00:00:00
abstract：:Matrix metalloproteinases (MMP) are a family of proteolytic enzymes that mediate the degradation of extracellular matrix macromolecules, including interstitial and basement membrane collagens, fibronectin, laminin, and proteoglycan core protein. The enzymes are secreted or released in latent form and become activated ...
journal_title：Journal of periodontology
pub_type： 杂志文章,评审
doi：10.1902/jop.1993.64.5s.474
更新日期：1993-05-01 00:00:00
abstract：:The purpose of this study was to evaluate interexaminer and intraexaminer probing force variations in various regions of the mouth and adjacent to different tooth surfaces. Fifty-eight dental clinicians composed of 13 periodontists, 15 general dentists, 15 hygienists and 15 senior dental students probed the facial sur...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1983.54.8.488
更新日期：1983-08-01 00:00:00
abstract：BACKGROUND:Periodontal disease is one of the major oral problems encountered in patients with diabetes mellitus (DM). Vascular changes, neutrophil dysfunction, altered collagen synthesis, and genetic predisposition observed in DM may contribute to periodontitis; and the vascular alterations observed in such patients ma...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2004.75.1.91
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:The aims of this study are to determine whether the antigen-inexperienced (naive, CD45RB high-density) T-cell (CD4(+)CD45RB(High) T-cell) transfer model is associated with alveolar bone resorption, to elucidate the local osteogenic/adipogenic potential of alveolar bone marrow stromal cells (ABCs) from T-cell...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2014.140077
更新日期：2014-09-01 00:00:00
abstract：:The prevalence of periodontitis was studied in a population of insulin-dependent diabetes mellitus (IDDM) patients, aged 10-18, with a variety of disease durations and levels of control. The sample included a number of patients with poorly controlled IDDM of long duration. None of the patients had radiographic signs o...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1984.55.7.402
更新日期：1984-07-01 00:00:00
abstract：BACKGROUND:Efficient methods to treat persistent pockets during periodontal maintenance therapy (PMT) require further investigation. The hypothesis of this randomized controlled clinical trial was that local application of enamel matrix derivative (EMD) added to papilla reflection/root preparation (PR/RP) could enhance...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1002/JPER.19-0623
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Guided bone regeneration (GBR) using a non-absorbable barrier has provided clinicians the ability to place implants in sites compromised by insufficient bone, including immediate extraction sites. Recent evidence suggests that successful GBR outcomes may be possible using bioabsorbable polymer barriers. MET...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2001.72.2.250
更新日期：2001-02-01 00:00:00
abstract：:Gingival crevicular fluid (GCF) levels of the polymorphonuclear leukocyte (PMN) lysosomal enzyme beta-glucuronidase (beta G), the pro-inflammatory cytokine interleukin 1 beta (IL-1 beta), and immunoglobulins (IgA, IgG, and IgM) were examined in 16 HIV seropositive (HIV+) and 10 HIV seronegative (HIV-) injecting drug u...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1997.68.3.249
更新日期：1997-03-01 00:00:00
abstract：:A randomized, double-blind, clinical study was done to assess the microbiological and clinical effects of metronidazole plus amoxicillin (M+A) as the only therapy in 46 patients with moderate to advanced progressive adult periodontitis. Patients were included in the study after at least 2 sites showed > or =2 mm clini...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1902/jop.1998.69.11.1291
更新日期：1998-11-01 00:00:00
abstract：BACKGROUND:The aerosol generated by an ultrasonic scaler contains microorganisms that can penetrate into the body through the respiratory system of dental surgeons and patients. The aim of this pilot study is to evaluate and compare the efficacy of commercially available preprocedural mouthrinses containing 0.2% chlorh...
journal_title：Journal of periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1902/jop.2013.120616
更新日期：2014-04-01 00:00:00
abstract：:Classification by origin and structure of the many different coatings which occur on the surfaces of teeth and artificial surfaces exposed to the oral environment necessitate a revision of the terminology used to describe these coatings. Numerous gaps still exist in our understanding of the origin, morphological struc...
journal_title：Journal of periodontology
pub_type： 杂志文章,评审
doi：10.1902/jop.1976.47.3.139
更新日期：1976-03-01 00:00:00
abstract：:Accurate diagnosis of periodontal destruction in the furcation region of multi-rooted teeth is a critical component of treatment planning, with different therapeutic approaches chosen based upon clinical determination of the severity of involvement. The current study assessed both vertical and horizontal depths of 274...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1994.65.7.649
更新日期：1994-07-01 00:00:00
abstract：:THIS INVESTIGATION was undertaken to determine the distribution pattern and readability level of 20 widely distributed printed items containing periodontal health education literature. Average annual distribution was obtained from distributors of the material. The Minnesota Interactive Readability Approximation Progra...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1983.54.9.538
更新日期：1983-09-01 00:00:00
abstract：:Fourteen intrabony periodontal defects and six furcation defects (Class II) were treated by a flap procedure which included the use of a polytetrafluoroethylene membrane to allow guided tissue regeneration. After 4 to 6 weeks of healing, the membranes were retrieved and examined by scanning electron microscopy for the...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1990.61.8.515
更新日期：1990-08-01 00:00:00
abstract：BACKGROUND:Neopterin, a marker of cellular immune activation, is produced by human macrophages after induction by interferon gamma that is secreted by T lymphocytes. Neopterin concentrations in diverse body fluids have been reported to increase in parallel with bacteria in the clinical course of infections. Therefore, ...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2002.73.7.720
更新日期：2002-07-01 00:00:00
abstract：:The objective of this study was to evaluate if the biologic membrane utilized for GTR can be impregnated by tetracycline hydrochloride and if the chemotherapeutic agent, once impregnated, can be released in minimal inhibitory concentrations for a period compatible with clinical application. Initially, an in vitro stud...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1995.66.11.978
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:The objective of this study is to determine whether simvastatin consumption and hyperlipidemia are associated with a worse periodontal condition and specific bone activity biomarkers. METHODS:This cross-sectional and analytic study includes 73 patients divided into three groups: 1) simvastatin-treated patie...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2014.130652
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:The present study was designed to evaluate the effect, if any, of citric acid root demineralization in the outcome of subepithelial connective tissue grafts performed to cover localized gingival recessions. METHODS:Thirty-six patients participated, each providing one gingival recession; 19 received citric a...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1902/jop.2000.71.4.568
更新日期：2000-04-01 00:00:00
abstract：:Free gingival grafts were placed in the lower anterior vestibular region of 30 patients each of whom had a gingival recession. According to the width of the recession and to the surgical procedure, the patients were divided into four groups. Group 1 showed a "narrow" (less than 3 mm) type of recession, while Group 2 h...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1976.47.10.574
更新日期：1976-10-01 00:00:00
abstract：BACKGROUND:This study evaluates the influence of platelet-rich plasma derived from bone marrow aspirate (PRP-BMA) on the healing of periodontal fenestration defects in rats. METHODS:Periodontal fenestration defects were surgically created in the mandibles of 40 rats. The animals were randomly divided into two groups, ...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2014.140083
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Cannabis sativa (marijuana) can interfere with bone physiopathology because of its effect on osteoblast and osteoclast activity. However, its impact on periodontal tissues is still controversial. The present study evaluates whether marijuana smoke affects bone loss (BL) on ligature-induced periodontitis in r...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2011.100362
更新日期：2011-11-01 00:00:00
abstract：:This investigation was conducted on seven individuals referred for treatment of moderate adult periodontitis. Twenty-eight sites with an average probing depth of 5.6 +/- 0.9 mm were evaluated. One tooth per jaw quadrant was randomly assigned to receive one of the following treatments: (I) no treatment, i.e., control; ...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1902/jop.1988.59.5.301
更新日期：1988-05-01 00:00:00
abstract：:The secretion of prostaglandin E2 (PGE2), tumor necrosis factor alpha (TNF alpha), interleukin 1 beta (IL-1 beta), and interleukin 6 (IL-6) by adherent mononuclear cells (AMNC) from 28 patients with early-onset periodontitis was studied. The early onset-periodontitis patients consisted of 12 patients with localized ju...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1994.65.2.139
更新日期：1994-02-01 00:00:00
abstract：:This study compared bite force discrimination between 14 treated periodontal patients with significant bone resorption and 14 control subjects who were free of periodontal disease. Bite force was measured using a strain gauge scale which permitted subjects to visually monitor when their bite force equaled a preset res...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1987.58.4.236
更新日期：1987-04-01 00:00:00
abstract：BACKGROUND:This study was conducted to assess the clinical, immunological, and patient-centered outcomes of microcurrent electrotherapy on palatal wound healing. METHODS:This was a parallel, double-masked randomized clinical trial, in which 53 patients with ridge preservation indications were selected and randomly ass...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1002/JPER.20-0122
更新日期：2020-08-12 00:00:00
