Abstract:
:This study showed histopathological findings of the extracellular matrix in healthy, inflamed, and hyperplastic human gingiva with immunohistochemical techniques. The distribution of collagen types V and VI, as well as of glycoprotein fibronectin, shows that they are extracellular matrix structural components which differentiate the tissue pathology. The orientation of the collagen fibers, the intensity of the fluorescent staining, the thickness of the fibrillar component, and the topographical localization of the connective tissue proteins are important parameters for tissue morphology. Therefore, bacterial deposits and the pharmacodynamic properties of drugs associated with gingival hyperplasia lead to an alteration of the matrix compared to the healthy tissues. This may be important in the tissue pathology in cases when the medical history of the patient is not known, as well as in forensic medicine.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Romanos GE,Strub JR,Bernimoulin JPdoi
10.1902/jop.1993.64.2.110subject
Has Abstractpub_date
1993-02-01 00:00:00pages
110-9issue
2eissn
0022-3492issn
1943-3670journal_volume
64pub_type
杂志文章abstract:BACKGROUND:In an attempt to evaluate the influence of cyclosporin A (CsA) on fibroblast metabolism, the phospholipase C beta1, (PLC beta1) nuclear expression was evaluated in fibroblasts from heart transplantation patients treated with CsA who exhibited gingival overgrowth (GO) and from controls. METHODS:PLC beta1 was...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.11.1722
更新日期:2000-11-01 00:00:00
abstract::This investigation was undertaken to compare the Gindex saliva test scores with the Gingival Index scores and crevicular fluid flow scores, as proposed by Löe and Holm-Pedersen. Eighty-one patients were tested using the Gindex chemical analysis kit. Crevicular fluid was collected from the six teeth advocated by Ramfjo...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1978.49.11.564
更新日期:1978-11-01 00:00:00
abstract:BACKGROUND:The role of keratinized tissue (KT) for maintenance of periodontal health has been debated for many years. This study assesses the long-term "biologic remodeling" of periodontal dimensions of teeth treated with free gingival grafts (FGGs) compared with adjacent/untreated teeth. METHODS:Seventy-four patients...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2017.170010
更新日期:2017-07-01 00:00:00
abstract::The purpose of this investigation was to evaluate calcium hydroxide and potassium nitrate individually as densensitizing agents for hypersensitive root surfaces. The apparatus used in the experiment to measure hypersensitivity was (a) a thermo-electric stimulating device to measure hot and cold stimulation quantitativ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1977.48.10.667
更新日期:1977-10-01 00:00:00
abstract::The relationship between diabetes mellitus and oral health status was determined in Pima Indians from the Gila River Indian Community in Arizona. This tribe of native Americans has the world's highest reported incidence and prevalence of non-insulin-dependent (type 2) diabetes mellitus. The probing attachment level, a...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1991.62.2.123
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:The aim of this split-mouth study is to compare long-term (18 to 35 years) periodontal conditions of sites treated with gingival augmentation procedures (GAPs) and untreated homologous contralateral sites. METHODS:Forty-seven patients with 64 sites (test group), with lack of attached gingiva associated with...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.160284
更新日期:2016-12-01 00:00:00
abstract::The purpose of this study was to identify factors which might affect the healing response in intrabony defects treated with guided tissue regeneration. Selected sites presented with deep periodontal lesions with 1, 2, and 3 wall combination intrabony component of 6.1 +/- 2.5 mm. The significance of patient, tooth, and...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.10.934
更新日期:1993-10-01 00:00:00
abstract::This study investigates the effects of the placement of a bioresorbable Type I collagen barrier on clinically healthy sites. Ten human subjects, with at least one pair of matched periodontal defects included in a previous study, were investigated for the effect of guided tissue regeneration (GTR) membrane placement on...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.1.57
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:The purpose of this clinical study is to evaluate the radiographic bone remodeling, survival rate, and soft tissue health surrounding a variable-thread tapered implant immediately placed in extraction sites. METHODS:Sixty implants were placed in 55 patients at six centers according to a predetermined protoc...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1902/jop.2013.120638
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Arachidonate-5-lipoxygenase (5-LO) activity and increased leukotriene B4 (LTB4) production have been implicated in various inflammatory conditions. Increased production of leukotrienes has been associated with periodontal diseases; however, their relative contribution to tissue destruction is unknown. In thi...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2017.170210
更新日期:2017-12-05 00:00:00
abstract:BACKGROUND:Controversy over the long-term clinical effectiveness of hydroxyapatite (HA)-coated dental implants still persists, despite numerous clinical studies documenting high survival rates. Concerns about the degradation of the coating over the years have been raised; it has been speculated that resorption of the H...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060271
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:β-glucuronidase (βG) is one of the enzymes involved in the destruction of non-collagenous components of the extracellular matrix. It is also considered an indicator or predictor of periodontal disease activity. The present study was conducted to determine the presence and the levels of βG activity in gingiva...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.4.618
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Volumetric alterations in gingival crevicular fluid (GCF) are widely accepted to be associated with periodontal health/disease. The volume/flow of GCF was shown to be affected by an array of methodological factors. However, relatively limited information is available on whether GCF is subject to circadian rh...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.130367
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Efficient methods to treat persistent pockets during periodontal maintenance therapy (PMT) require further investigation. The hypothesis of this randomized controlled clinical trial was that local application of enamel matrix derivative (EMD) added to papilla reflection/root preparation (PR/RP) could enhance...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.19-0623
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Gingival thickness, keratinized tissue width, and bone morphotype are three important parameters used to categorize periodontal phenotypes. These elements all play an important role in the maintenance of periodontal health. The aim of this review is to explore the importance of converting thin phenotype into...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1002/JPER.19-0337
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:The microbiologic feature of aggressive periodontitis (AgP) in Chinese patients has not yet been determined. This study aims to investigate the prevalence of eight periodontal microorganisms and the distribution of the Porphyromonas gingivalis fimA genotype in a cohort of Chinese patients with AgP. METHODS:...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.120677
更新日期:2014-01-01 00:00:00
abstract::Periodontal conditions and salivary levels of immunoglobulins sIgA, IgM, and IgG subclass distribution and albumin, quantified by enzyme-linked immunosorbent assay, were determined in 20 patients with Down syndrome and 19 healthy controls. Gingival inflammation was more extensive (P < 0.05) among Down syndrome subject...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1998.69.10.1119
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:Various surgical techniques have been proposed for treating gingival recession. This randomized clinical trial compared the coronally positioned flap (CPF) alone or in conjunction with a subepithelial connective tissue graft (SCTG) in the treatment of gingival recession. METHODS:Eleven non-smoking subjects ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2004.75.3.413
更新日期:2004-03-01 00:00:00
abstract::This review defines terms such as accuracy, validity, and reliability, which are used to describe the quality of methods for taking x-rays and for analyzing digital images. Values for these parameters are described for techniques of taking standardized x-rays such as ear-rod fixation and fixation by use of teeth with ...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2000.71.3.497
更新日期:2000-03-01 00:00:00
abstract::The Keyes technique came to national attention following a reference in The New York Times in the late 1970s. Several lay press articles and discussions on national television served to further focus the interest of patients, general dentists, and periodontists on this potential approach to periodontal therapy. Early ...
journal_title:Journal of periodontology
pub_type: 杂志文章,收录出版
doi:
更新日期:1998-08-01 00:00:00
abstract:BACKGROUND:Oscillating-rotating power toothbrushes have been proven to be clinically efficacious. To the best of the authors' knowledge, a clinical evaluation of the safety of these toothbrushes after surgical root coverage procedures has not been published. The aim of this study is to evaluate the gingival margin (GM)...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2016.150528
更新日期:2016-10-01 00:00:00
abstract::Demineralized bone matrix (DBM) is widely used in the repair of pathologies associated with skeletal defects and periodontal diseases. The present study was directed at establishing in vivo and in vitro models for a quantitative assessment of the osteoinductivity of DBM before clinical use. Athymic mice were used in a...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1997.68.11.1076
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the effect of the association of locally delivered doxycycline 10% and scaling and root planing in the subgingival plaque of smokers. METHODS:Sixteen smokers with chronic periodontitis and a minimum of four pockets (> or = 5 mm) on anterior teeth that bled on probing we...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2004.75.12.1600
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Simvastatin has been shown to stimulate new bone growth on rat mandibles, but much of the bone is lost over time. The purpose of this study is to evaluate the impact of a locally or systemically applied antiresorptive agent (alendronate) on simvastatin-induced bone formation in and adjacent to a rat periodon...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.110683
更新日期:2012-12-01 00:00:00
abstract::This investigation was conducted on seven individuals referred for treatment of moderate adult periodontitis. Twenty-eight sites with an average probing depth of 5.6 +/- 0.9 mm were evaluated. One tooth per jaw quadrant was randomly assigned to receive one of the following treatments: (I) no treatment, i.e., control; ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1988.59.5.301
更新日期:1988-05-01 00:00:00
abstract::In order to compare the effect of partial demineralization with root planing and partial demineralization of cementum with that of dentin on healing, the ultrastructural morphology of the interface between the layer of human periodontal ligament-derived, fibroblast-like cells (HPF) and the treated root surface was stu...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.4.267
更新日期:1995-04-01 00:00:00
abstract::The botryoid odontogenic cyst is considered to be a multiloculated variant of the lateral periodontal cyst. Fewer than 40 of these lesions have been described, many of which have recurred. This paper describes the demographic, clinical, microscopic, and radiographic features of 33 unreported cases from the files of th...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.12.1069
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND:Dendritic cells are characterized by shape, structure, and membrane molecule expression; they contact T lymphocytes to present antigens and stimulate plasma cell differentiation in vitro. Dendritic cells are known to be present in healthy human gingiva and to be altered in HIV-associated periodontitis. Here,...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2002.73.1.45
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The purpose of the present study was to assess the effects of adjunctive meloxicam on the matrix metalloproteinase-8 (MMP-8) levels of gingival crevicular fluid (GCF) in chronic periodontitis patients following the initial phase of periodontal therapy. METHODS:Twelve chronic periodontitis patients received ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2002.73.1.103
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The long-term survival of dental implants depends, in part, on control of bacterial infection in the peri-implant region. Periodontal pathogens colonized implants symptomatic through infection, whereas the microbiota of successful implants was similar to that of periodontal health. This study examined the im...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.2.131
更新日期:1999-02-01 00:00:00