Abstract:
BACKGROUND:β-glucuronidase (βG) is one of the enzymes involved in the destruction of non-collagenous components of the extracellular matrix. It is also considered an indicator or predictor of periodontal disease activity. The present study was conducted to determine the presence and the levels of βG activity in gingival tissue and gingival crevicular fluid (GCF) in periodontal disease and health status. The validity of 2 expressions of data, total βG activity versus βG concentration, and the correlations between clinical periodontal status and βG profile was also evaluated. METHODS:βG activities in gingival tissues and GCF samples from 57 individuals, divided into 3 equal groups of adult periodontitis (AP), early-onset periodontitis (EOP), and periodontally healthy subjects were spectrophotometrically examined. RESULTS:Both patient groups had higher βG levels in both gingiva and GCF than controls. Significant differences were observed among all groups when total GCF βG activities were examined (P <0.05). However, the difference between AP and controls was not significant when concentration values were compared (P >0.05). The highest GCF βG activity, with both expressions, was detected in EOP group. No absolute correlations between clinical parameters and βG activity were observed, except for random correlations in the patient groups with mean total βG activities. Also GCF/gingiva βG levels and the 2 expressions did not show absolute correlations. CONCLUSIONS:The findings of the present study confirm the relationship between βG activity and periodontal diseases. The differences in data concerning GCF total βG activity and βG concentration may suggest that they are not matching measures. Data presentation seems to be an important factor in GCF/enzyme profile studies. J Periodontol 2000;71:618-624.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Layik M,Yamalik N,Çaglayan F,Kilinç K,Etikan I,Eratalay Kdoi
10.1902/jop.2000.71.4.618subject
Has Abstractpub_date
2000-04-01 00:00:00pages
618-624issue
4eissn
0022-3492issn
1943-3670journal_volume
71pub_type
杂志文章abstract:BACKGROUND:The purpose of this study is to evaluate whether β-tricalcium phosphate (β-TCP) could be a promising modality to help augment alveolar bone in periodontal tissue regeneration by bone marrow mesenchymal stem cells (BMMSCs). METHODS:Expanded BMMSCs and atelocollagen (Col) were mixed together (MSC/Col). A comb...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.140384
更新日期:2015-03-01 00:00:00
abstract::Periodontitis is a chronic inflammatory disease of the soft and hard supporting tissues of the teeth and is a major cause of tooth loss in adults. The local host response to periodontopathic bacteria results in the release of inflammatory mediators and cytokines. Since cytokines are indicative of effector functions, w...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1996.67.5.515
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:Despite previous studies addressing the link between preterm or low birth weight infants and maternal periodontitis, extreme preterm births have received far less attention. This study is designed to address the possible association between maternal periodontal disease and preterm or extreme preterm birth. ...
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journal_title:Journal of periodontology
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doi:10.1902/jop.2010.100540
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:The aim of this 9-month reentry study was to compare the regenerative healing using porous (P) and non-porous (NP) teflon barrier membranes plus demineralized freeze dried bone allografts (DFDBA) in Class II buccal/lingual furcation defects. METHODS:Twenty-four patients, 13 males and 11 females, ages 38 to ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-11-01 00:00:00
abstract::A case of osseous hyperplasia under the pontics of fixed partial dentures in right and left mandibular first molar regions is presented. Radiographs showed hemispherical radio-opacities on the alveolar ridges. Histologic examination revealed the lesions were composed of a dense mass of mature bone with well-developed ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.5.311
更新日期:1988-05-01 00:00:00
abstract:BACKGROUND:Periodontitis is associated with increased prevalence of cardiovascular morbidity and mortality; however, the nature of this association is unclear. There is a rationale that indicates that the presence of periodontal pockets which can harbor pathogenic microorganisms and evoke a host response could elicit a...
journal_title:Journal of periodontology
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doi:10.1902/jop.2002.73.5.494
更新日期:2002-05-01 00:00:00
abstract::The purpose of this study was to determine the clinical course of early onset periodontitis and to investigate factors which may influence its clinical course. For the past 15 years we have been conducting a study of families with early onset periodontitis, and have examined 142 localized juvenile periodontitis and 18...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.5.321
更新日期:1995-05-01 00:00:00
abstract::The advent of AIDS has created patients fears regarding human tissue transfers, including bone grafts in dental surgery. In the face of these fears, alternative allograft materials are of increasing interest to clinicians. One such alternative is naturally derived xenogeneic hydroxyapatite (HA). In this study, two pat...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.6.575
更新日期:1993-06-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.19-0342
更新日期:2020-07-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100417
更新日期:2011-03-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1979.50.2.75
更新日期:1979-02-01 00:00:00
abstract::Standard wounds of simple incision and partial excision of the dentogingival junction were made in miniature swine. The healing from the 1st to the 14th day were described clinically and histologically, and the standardization of the wounds permitted quantitative and statistical analysis. In wounds that are closely ad...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1980.51.6.318
更新日期:1980-06-01 00:00:00
abstract:BACKGROUND:Porphyromonas gingivalis is one of the major microbial pathogens associated with chronic periodontitis. To eradicate such pathogens by periodontal therapy, it is essential to clarify the source of infection. Recent findings suggest that the genotype of the fimbriae is one of the important factors in infectio...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.9.1355
更新日期:2003-09-01 00:00:00
abstract::Accumulating evidence suggests that chronic infections, such as periodontitis, are associated with increased risk for cardiovascular diseases (CVD). The mechanisms behind the association are not known. Like herpes viruses and Chlamydia pneumoniae, periodontal pathogens cause atherosclerosis in experimental animals and...
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doi:10.1902/jop.2005.76.11-S.2085
更新日期:2005-11-01 00:00:00
abstract::Subtraction radiography requires radiographs made with identical projection geometry. Recently a new radiographic aiming device and an x-ray beam manipulator made it possible to repeat radiographic exposures in vivo with small angular errors and to measure the angular errors occurring. The purpose of the present inves...
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pub_type: 杂志文章
doi:10.1902/jop.1993.64.4.278
更新日期:1993-04-01 00:00:00
abstract:BACKGROUND:Interleukin-18 (IL-18) is reported as an important regulatory cytokine in non-oral inflammation. Our objective was to compare the concentrations of IL-18 within diseased and healthy human gingiva with concentrations of other T(H)1 and T(H)2 cytokines to determine possible effects of IL-18 on gingival inflamm...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.5.785
更新日期:2005-05-01 00:00:00
abstract::The clinical periodontal status of 44 insulin-dependent diabetic children and adolescents and 20 healthy control subjects was compared for a period of approximately 5 years. Fasting blood glucose, fructosamine, and glycosylated hemoglobin (HbA1) values were determined at baseline and 5 years later. The differences in ...
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pub_type: 杂志文章
doi:10.1902/jop.1997.68.2.136
更新日期:1997-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1902/jop.1992.63.5.457
更新日期:1992-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1902/jop.1999.70.11.1361
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journal_title:Journal of periodontology
pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.10.602
更新日期:1985-10-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1986.57.7.422
更新日期:1986-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1902/jop.2005.76.8.1362
更新日期:2005-08-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2013-04-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.9.1492
更新日期:2000-09-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:1997-06-01 00:00:00
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pub_type: 临床试验,杂志文章
doi:10.1902/jop.2002.73.3.317
更新日期:2002-03-01 00:00:00
abstract::Linear IgA disease (LAD) is a chronic, subepithelial blistering disease that is associated with the presence of linear deposits of IgA along the basement membrane zone. Etiopathogenic aspects of LAD are only partially known. LAD is clinically characterized by vesiculobullous skin and mucous lesions. Although more than...
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pub_type: 杂志文章
doi:10.1902/jop.2003.74.6.879
更新日期:2003-06-01 00:00:00