Interaction of penicillin with HLA-A and -B antigens.

abstract：:Population studies represent an integral part, and a necessary link in a complex chain of host-pathogen interactions, disease pathogenesis, and major histocompatibility complex polymorphism. HLA class I and class II allele and haplotype distributions among Venezuelan mestizos were determined. Genes of Mongoloid, Negro...

journal_title：Human immunology

authors： Makhatadze NJ,Franco MT,Layrisse Z

更新日期：1997-06-01 00:00:00

abstract：:The immunomodulatory properties of soluble human leukocyte antigen G (sHLA-G) explain its potential interest in malignancies. HLA-G frequently transcribed in lymphoproliferative disorders is rarely expressed at cell surface. In this article, we will demonstrate that the plasmatic level of soluble HLA-G was significant...

journal_title：Human immunology

authors： Sebti Y,Le Friec G,Pangault C,Gros F,Drénou B,Guilloux V,Bernard M,Lamy T,Fauchet R,Amiot L

更新日期：2003-11-01 00:00:00

abstract：:The allelic diversity and associated human leukocyte antigen (HLA) disparity of 1775 bone marrow recipients and their unrelated donors, matched for six of six (1361/1775,77%), five of six (397/1775, 22%), or four of six (17/1775, 1%) HLA-A, -B, -DR antigens, were retrospectively evaluated. The comprehensive HLA analys...

journal_title：Human immunology

authors： Hurley CK,Fernandez-Vina M,Hildebrand WH,Noreen HJ,Trachtenberg E,Williams TM,Baxter-Lowe LA,Begovich AB,Petersdorf E,Selvakumar A,Stastny P,Hegland J,Hartzman RJ,Carston M,Gandham S,Kollman C,Nelson G,Spellman S,Sett

更新日期：2007-01-01 00:00:00

abstract：:The relevance of pre-existing HLA-antibodies (HLA-Ab) in liver transplantation (LTx) is controversial. While livers are allocated without HLA match or preoperative crossmatch testing, several studies point to an impact of donor specific antibodies (DSA) for acute rejection, bile duct complications or even graft loss. ...

journal_title：Human immunology

authors： Koch M,Marget M,Sterneck M,Fischer L,Thude H,Nashan B

更新日期：2018-07-01 00:00:00

abstract：:To ascertain association of MICA with type 1 diabetes (T1D) in the Belgian population, well-characterized antibody-positive patients were analyzed for MICA transmembrane gene polymorphism in both an association study and a nuclear family study. The frequency of MICA5 was significantly increased in the T1D patient grou...

journal_title：Human immunology

authors： Van Autreve JE,Koeleman BP,Quartier E,Aminkeng F,Weets I,Gorus FK,Van der Auwera BJ,Belgian Diabetes Registry.

更新日期：2006-01-01 00:00:00

abstract：:In order to investigate the distribution of epitopes recognized by T-cell clones directed against HLA class II products, bulk primed cell populations were generated using cells matched for class I determinants but disparate for class II determinants. Cells were cloned by single cell deposition (FACS IV) or limiting di...

journal_title：Human immunology

authors： Reinsmoen NL,Bach FH

更新日期：1986-08-01 00:00:00

abstract：:Mannose-binding lectin (MBL) role in the carriage of oropharyngeal bacteria is not known. We investigated the association of smoking, MBL2 polymorphisms, and MBL concentrations with oropharyngeal carriage of respiratory bacteria in young men. Oropharyngeal specimens, MBL concentrations, and MBL2 gene polymorphisms wer...

journal_title：Human immunology

authors： Jounio U,Rantala A,Bloigu A,Juvonen R,Lajunen T,Silvennoinen-Kassinen S,Peitso A,Vainio O,Harju T,Saukkoriipi A,Leinonen M

更新日期：2010-03-01 00:00:00

abstract：:DNA sequence-based typing at the HLA-A, -B, -C, -DPA1, -DPB1, -DQA1, -DQB1, -DRB1, and -DRB3/4/5 loci was performed on samples provided by 159 individuals from the Worcester region of the Western Cape province of South Africa. The purpose of the study was to characterize allele frequencies in the local population, to ...

journal_title：Human immunology

authors： Grifoni A,Sidney J,Carpenter C,Phillips E,Mallal S,Scriba TJ,Sette A,Lindestam Arlehamn CS

更新日期：2018-03-01 00:00:00

abstract：:A large percentage of healthy individuals (50-90%) is chronically infected with Cytomegalovirus (CMV). Over the past few years, several techniques were developed in order to monitor CMV-specific T-cell responses. In addition to the identification of antigen-specific T cells with peptide-loaded MHC complexes, most of t...

journal_title：Human immunology

authors： Harari A,Zimmerli SC,Pantaleo G

更新日期：2004-05-01 00:00:00

abstract：INTRODUCTION:Tyrosine kinase 2 gene (TYK2) is part of the janus kinase (JAK) that binds to the type I interferon-α receptor (IFNAR) on the cell surface of IFN-producing cells, and have crucial importance in the etiology of autoimmune and inflammatory diseases. Many polymorphisms of the TYK2 gene have been identified, a...

journal_title：Human immunology

authors： Peluso C,Christofolini DM,Goldman CS,Mafra FA,Cavalcanti V,Barbosa CP,Bianco B

更新日期：2013-01-01 00:00:00

abstract：:FOXP3(+) regulatory T cells, a unique subset of T cells, are critical for orchestrating an immune response and preventing self-reactivity. With the increasing prevalence and unsatisfactory treatment of autoimmunity, allergic diseases, cancer and chronic infections, much attention has been focused on understanding thei...

journal_title：Human immunology

authors： Tran DQ,Shevach EM

更新日期：2009-05-01 00:00:00

abstract：:The compatibility of HLA-A,-B expression between mother and offspring was examined in 410 families serologically tissue typed within a single transplant lab from 1972 thru 1982. The study group included 410 mothers of 1719 children (range 2-13/mother), with 352 one-father and 58 multiple-father families There were sev...

journal_title：Human immunology

authors： MacQueen JM,Sanfilippo FP

更新日期：1984-11-01 00:00:00

abstract：:To test the involvement of osteopontin gene (OPN) in systemic sclerosis (SSc) susceptibility, two OPN single nucleotide polymorphisms previously reported to be associated with systemic lupus erythematosus, namely -156G/GG (proximal promoter) and +1239A/C (3' untranslated region (UTR)), were tested in 357 Italian patie...

journal_title：Human immunology

authors： Barizzone N,Marchini M,Cappiello F,Chiocchetti A,Orilieri E,Ferrante D,Corrado L,Mellone S,Scorza R,Dianzani U,D'Alfonso S

更新日期：2011-10-01 00:00:00

abstract：:Rapamycin contributes to the expansion of regulatory T cells (Tregs) in vitro. We investigated CD4(+)CD25(high)CD127(low) Treg level dynamics as well as the major parameters of cell immunity and sCD25 and highly sensitive C-reactive protein (hsCRP) concentrations in the blood of patients after coronary stenting (CS) w...

journal_title：Human immunology

authors： Potekhina AV,Provatorov SI,Sokolov VO,Pylaeva EA,Masenko VP,Noeva EA,Kukhtina NB,Krasnikova TL,Arefieva TI

更新日期：2011-07-01 00:00:00

abstract：:The HER-2/neu protein is overexpressed in approximately 20% of human adenocarcinomas and is a defined tumor antigen in breast cancer. The purpose of this study was to evaluate the endogenous HER-2/neu specific antibody response in 57 patients with colorectal cancer. HER-2/neu specific antibodies, titer > or = 1:100, w...

journal_title：Human immunology

authors： Ward RL,Hawkins NJ,Coomber D,Disis ML

更新日期：1999-06-01 00:00:00

abstract：:This article hashas been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Human immunology

authors： Li T,Huang H,Liao D,Ling H,Su B,Cai M

更新日期：2015-11-14 00:00:00

abstract：:The number of units and especially the number of different HLA haplotypes present in a cord blood (CB) bank is a crucial determinant of its usefulness. We generated data relevant to the development of our national CB in Finland. The HLA haplotype distribution was examined between specific populations. We developed gra...

journal_title：Human immunology

authors： Haimila K,Penttilä A,Arvola A,Auvinen MK,Korhonen M

更新日期：2013-02-01 00:00:00

abstract：:We have characterized the T lymphocyte population of the human neonate in respect of the expression of phenotypic profiles for naive, memory and differentiated populations. We have examined the response of the neonate T cell to the superantigen Staphylococcus enterotoxin B (SEB) and compared the response to T cells fr...

journal_title：Human immunology

authors： Macardle PJ,Wheatland L,Zola H

更新日期：1999-02-01 00:00:00

abstract：:Interactions between human IgG with human FcgammaRI and FcgammaRIIa (R131) were studied to investigate the role of the hinge region of IgG3 and IgG1 in the binding of the antibodies to FcgammaR. It was found that a hinge deletion mutant of IgG3 (IgG3 m15) was reduced in its ability to bind to FcgammaRI and FcgammaRIIa...

journal_title：Human immunology

authors： Redpath S,Michaelsen TE,Sandlie I,Clark MR

更新日期：1998-11-01 00:00:00

abstract：:Our objective was to study a possible contribution of MHC genes to S-HLA-I secretion in patients with Type I diabetes. Quantitatively, we used a highly sensitive enzyme-linked immunoassay to measure S-HLA-I in the serum of a total of 39 patients with Type I diabetes, as well as 36 kinships of 12 diabetic patients and ...

journal_title：Human immunology

authors： Adamashvili I,McVie R,Gelder F,Gautreaux M,Jaramillo J,Roggero T,McDonald J

更新日期：1997-07-01 00:00:00

abstract：:The genetic polymorphism of the fourth component of human complement, C4, was studied in 945 unrelated Caucasian individuals. A third allele of the C4F (Rodgers) locus, termed C4F1 was demonstrated. This allele is characterized using immunofixation electrophoresis, by the presence of an additional fast-moving anodal b...

journal_title：Human immunology

authors： O'Neill GJ,Miniter P,Pollack MS,Dupont B

更新日期：1980-07-01 00:00:00

abstract：:The association between single-nucleotide polymorphisms -174G/C (rs1800795) and -572G/C (rs1800796) in the interleukin-6 (IL-6) gene promoter region and ischemic heart disease (IHD)/ischemic stroke (IS) remains controversial and ambiguous. In this study, we performed a more precise estimation of the relationship by a ...

journal_title：Human immunology

authors： Ma Y,Tang RK,Yang X,Peng GG,Liu Y,Wang XM,Wu BH,Yu JM

更新日期：2011-08-01 00:00:00

abstract：:Better outcome for hematopoietic stem cell transplantation (HSCT) requires optimal matching between donor and recipient at the HLA-A, -B, -C, and -DRB1 loci. This study estimates the likelihood of identifying HLA matched donors in Hong Kong. 7595 volunteer unrelated Chinese donors at the Hong Kong Bone Marrow Donor Re...

journal_title：Human immunology

authors： Kwok J,Guo M,Yang W,Ip P,Chan GCF,Ho J,Lee CK,Middleton D,Lu L

更新日期：2017-10-01 00:00:00

abstract：:This review focuses on the role of antigen-specific T cells that mediate active inhibition of immune responses over the past 35 years since their initial description. The field has experienced several changes in the accepted paradigm of such suppressor/regulatory T cells, from initial indications that such cells were ...

journal_title：Human immunology

authors： Kapp JA,Bucy RP

更新日期：2008-11-01 00:00:00

abstract：:During HLA-DQ oligotyping, the presence of a novel HLA-DQB1 allele was suggested by a pattern of probe hybridization that was inconsistent with the presence of any possible combination of two known alleles. The nucleotide sequence of the second exon of the HLA-DQB1 gene was determined, revealing a novel HLA-DQB1 seque...

journal_title：Human immunology

authors： Fenske TS,Baxter-Lowe LA

更新日期：1992-03-01 00:00:00

abstract：:Platelet alloimmunization may result in post-transfusion purpura, and during pregnancy may cause neonatal alloimmune thrombocytopenia (NAIT), with a frequency estimated at 1.3 per 1000 live births. The risk of morbidity is significant: 20% of affected infants have neurologic sequelae and the death rate is about 10%. A...

journal_title：Human immunology

authors： Semana G,Zazoun T,Alizadeh M,Morel-Kopp MC,Genetet B,Kaplan C

更新日期：1996-04-01 00:00:00

abstract：:RING 11, a second transport-associated gene (TAP2), has been recently identified in the DR-DP interval of the human class II region. Two predominant alleles, TAP2A and TAP2B, differing by 17 amino acids at the C-terminus of the ATP-binding domain are present in the Caucasoid population at frequencies of 79% and 21%, r...

journal_title：Human immunology

authors： Eiermann TH,Fakler J,Goldmann SF,Böhm BO

更新日期：1993-11-01 00:00:00

abstract：:Accurate identification of HLA antibodies using the single antigen bead (SAB) assay is critical for assessment of pre/post-transplant immunological risk and successful virtual crossmatching. Unfortunately, high titer HLA antibodies can be missed or underestimated in the SAB assay as a result of interference with the d...

journal_title：Human immunology

authors： Greenshields AL,Liwski RS

更新日期：2019-07-01 00:00:00

abstract：:Positive selection of immature thymocytes is a developmental process in which TCR ligation with low avidity induces generation of mature T cells. In mouse thymocytes, CD4(+)8(+) double-positive (DP) cells which were treated with a proper combination of calcium ionophore ionomycin and phorbol 12-myristate 13-acetate (P...

journal_title：Human immunology

authors： Tanahashi M,Yokoyama T,Kobayashi Y,Yamakawa Y,Maeda M,Fujii Y

更新日期：2001-08-01 00:00:00

abstract：:Homozygous carriers of CCR5-Δ32, a gene variant of CC-type chemokine receptor 5 (CCR5), are highly resistant to infections with human immunodeficiency virus type 1 (HIV-1) and therefore preferred stem cell donors for HIV-infected patients. We analyzed CCR5 typing data of 1,333,035 potential hematopoietic stem cell don...

journal_title：Human immunology

authors： Solloch UV,Lang K,Lange V,Böhme I,Schmidt AH,Sauter J

更新日期：2017-11-01 00:00:00