Abstract：
:Conditions of the efficient production of tick-borne encephalitis (TBE) virus in chick embryo cell (CEC) monolayer cultures were investigated. The prerequisites of high recovery of the produced virus appeared to be: the use of dense cell monolayers, reasonable frequency of harvests and a suitable buffering of nutrient media. Using low input multiplicity of infection, the peak of the serum-free virus production was observed between 24 and 48 hr post infection (p.i.). The procedure elaborated was useful for isotopic labelling of the virus.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Slávik I,Ciampor F,Mayer Vsubject
Has Abstractpub_date
1983-03-01 00:00:00pages
97-104issue
2eissn
0001-723Xissn
1336-2305journal_volume
27pub_type
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