Unconventional methyl galactan synthesized via the thexyldimethylsilyl intermediate: preparation, characterization, and properties.

Abstract:

:Reaction of a beta-(1 --> 4) linked galactan with TDMS chloride followed by methylation and desilylation yields methyl galactans with unconventional functionalization patterns. The products were characterized via FTIR and NMR of the intact polymer and by CE after controlled depolymerization. A TDMS-derivatized methyl galactan contains differently methylated secondary hydroxyl groups. SEC and analytical ultracentrifugation showed a consistent decrease in the molecular weight after the consecutive reaction steps. Biological studies revealed that the methyl galactans are less active in complement fixation assays as compared with a 3-O-methyl galactan-enriched polysaccharide fraction isolated from Acanthus ebracteatus.

journal_name

Macromol Biosci

authors

Koschella A,Inngjerdingen K,Paulsen BS,Morris GA,Harding SE,Heinze T

doi

10.1002/mabi.200700120

subject

Has Abstract

pub_date

2008-01-09 00:00:00

pages

96-105

issue

1

eissn

1616-5187

issn

1616-5195

journal_volume

8

pub_type

杂志文章
  • New insight into biodegradation of polylactide (PLA)/clay nanocomposites using molecular ecological techniques.

    abstract::Novel molecular ecological techniques were used to study changes in microbial community structure and population during degradation of polylactide (PLA)/organically modified layered silicates (OMLS) nanocomposites. Cloned gene sequences belonging to members of the phyla Actinobacteria and Ascomycota comprized the most...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200800276

    authors: Sangwan P,Way C,Wu DY

    更新日期:2009-07-07 00:00:00

  • Phosphodiester Hydrogels for Cell Scaffolding and Drug Release Applications.

    abstract::Given the major structural role phosphodiesters play in the organism it is surprising they have not been more widely adopted as a building block in sophisticated biomimetic hydrogels and other biomaterials. The potential benefits are substantial: phosphoester-based materials show excellent compatibility with blood, ce...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201900090

    authors: Dera R,Diliën H,Billen B,Gagliardi M,Rahimi N,Van Den Akker NMS,Molin DGM,Grandfils C,Adriaensens P,Guedens W,Cleij TJ

    更新日期:2019-07-01 00:00:00

  • The biodeterioration of synthetic resins used in conservation.

    abstract::Synthetic resins have been extensively employed by artists in their works of art, e.g. as paint binders, or by conservators for conservation treatments, e.g. as stone consolidants and protectives. It is generally thought that synthetic resins are less prone to chemical, physical and biological deterioration than other...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章,评审

    doi:10.1002/mabi.200300055

    authors: Cappitelli F,Zanardini E,Sorlini C

    更新日期:2004-04-19 00:00:00

  • Hydrophilic core-shell microspheres: a suitable support for controlled attachment of proteins and biomedical diagnostics.

    abstract::Functional hydrophilic microspheres (latex particles) have found various applications in life sciences and in medicine - particularly in latex diagnostic tests. This paper presents a comprehensive review of studies on latex particles with a hydrophilic interfacial layer composed of various hydrophilic polymers with re...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章,评审

    doi:10.1002/mabi.200500138

    authors: Basinska T

    更新日期:2005-12-15 00:00:00

  • Poly(anhydride-ester) and poly(N-vinyl-2-pyrrolidone) blends: salicylic acid-releasing blends with hydrogel-like properties that reduce inflammation.

    abstract::Polymers such as poly(N-vinyl-2-pyrrolidone) (PVP) have been used to prepare hydrogels for wound dressing applications but are not inherently bioactive. For enhanced healing, PVP was blended with salicylic acid-based poly(anhydride-esters) (SAPAE) and shown to exhibit hydrogel properties upon swelling. In vitro releas...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201400238

    authors: Ouimet MA,Fogaça R,Snyder SS,Sathaye S,Catalani LH,Pochan DJ,Uhrich KE

    更新日期:2015-03-01 00:00:00

  • Design of a Novel Two-Component Hybrid Dermal Scaffold for the Treatment of Pressure Sores.

    abstract::The aim of this study is to design a novel two-component hybrid scaffold using the fibrin/alginate porous hydrogel Smart Matrix combined to a backing layer of plasma polymerized polydimethylsiloxane (Sil) membrane to make the fibrin-based dermal scaffold more robust for the treatment of the clinically challenging pres...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201700185

    authors: Sharma V,Kohli N,Moulding D,Afolabi H,Hook L,Mason C,García-Gareta E

    更新日期:2017-11-01 00:00:00

  • pH-Triggered Self-Assembly of Cellulose Oligomers with Gelatin into a Double-Network Hydrogel.

    abstract::Multicomponent systems for self-assembled molecular gels provide huge opportunities to generate collective or new functions that are not inherent in individual single-component gels. However, gelation tends to require careful and complicated procedures, because, among a myriad of kinetically trapped structures related...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.202000187

    authors: Hata Y,Kojima T,Maeda T,Sawada T,Serizawa T

    更新日期:2020-09-01 00:00:00

  • Molecular Mechanism Study on Effect of Biodegradable Amino Acid Ester-Substituted Polyphosphazenes in Stimulating Osteogenic Differentiation.

    abstract::Amino acid ester substituted polyphosphazenes are osteoactive benefiting from their phosphorus-containing chemical structure, which highlights interests in bone tissue engineering. To correlate their chemical structures with cell activities, in this study, poly[(ethyl alanato)0.3 (ethyl glycinato)0.7 phosphazene] (PAG...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201800464

    authors: Huang Z,Yang L,Hu X,Huang Y,Cai Q,Ao Y,Yang X

    更新日期:2019-06-01 00:00:00

  • Curcumin Targeted, Polymalic Acid-Based MRI Contrast Agent for the Detection of Aβ Plaques in Alzheimer's Disease.

    abstract::Currently, there is no gadolinium-based contrast agent available for conventional magnetic resonance imaging (MRI) detection of amyloidal beta (Aβ) plaques in Alzheimer's disease (AD). Its timely finding would be vital for patient survival and quality of life. Curcumin (CUR), a common Indian spice effectively binds to...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201500062

    authors: Patil R,Gangalum PR,Wagner S,Portilla-Arias J,Ding H,Rekechenetskiy A,Konda B,Inoue S,Black KL,Ljubimova JY,Holler E

    更新日期:2015-09-01 00:00:00

  • Cloning of poly(aspartic acid) (PAA) hydrolase-1 gene from Pedobacter sp. KP-2 and hydrolysis of thermally synthesized PAA by its gene product.

    abstract::Pedobacter sp. KP-2 can degrade and metabolize thermally synthesized alpha,beta-poly(D,L-aspartic acid) (tPAA), which contains 70% of unnatural beta-amide units, with high-molecular-weight. In this study, gene cloning and molecular characterization of PAA hydrolase-1 from KP-2 was carried out. Gene analysis reveals th...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200800106

    authors: Hiraishi T,Masuda E,Kanayama N,Nagata M,Doi Y,Abe H,Maeda M

    更新日期:2009-01-09 00:00:00

  • A biodegradable polymersome with pH-tuning on-off membrane based on poly(β-amino ester) for drug delivery.

    abstract::A nanoscale biodegradable polymersome with pH-tuning on-off membrane is prepared via the self-assembly of poly(β-amino ester)-based amphiphilic copolymers. The pH-sensitive polymersome-like vesicle structure includes two layers that can encapsulate either hydrophobic or hydrophilic therapeutic drugs at physiological p...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201200468

    authors: Jeong IK,Gao GH,Li Y,Kang SW,Lee DS

    更新日期:2013-07-01 00:00:00

  • Carbon nanotubes fed on "carbs": coating of single-walled carbon nanotubes by dextran sulfate.

    abstract::A facile and easily reproducible technique for assembling biohybrid nanoparticles is a core feature that is highly desired for biomedical applications, considering the nature and limited lifespan of the biopolymers used. Here we show a simple and effective method to enfold single-walled carbon nanotubes (SWNTs) using ...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200900349

    authors: Kotagiri N,Kim JW

    更新日期:2010-03-10 00:00:00

  • Poly(ethylene glycol) grafting to poly(ether imide) membranes: influence on protein adsorption and thrombocyte adhesion.

    abstract::The chain length and end groups of linear PEG grafted on smooth surfaces is known to influence protein adsorption and thrombocyte adhesion. Here, it is explored whether established structure function relationships can be transferred to application relevant, rough surfaces. Functionalization of poly(ether imide) (PEI) ...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201300309

    authors: Neffe AT,von Ruesten-Lange M,Braune S,Luetzow K,Roch T,Richau K,Jung F,Lendlein A

    更新日期:2013-12-01 00:00:00

  • Synthesis and erosion properties of PEG-containing polyanhydrides.

    abstract::To tailor the erosion rate of polyanhydrides while retaining their surface erosion characteristics, new three-component polyanhydrides of sebacic acid, 1,3-bis(p-carboxyphenoxy)propane and poly(ethylene glycol) were synthesized. The hydrophilicity of the polymer increased and its mechanical strength decreased with inc...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200600256

    authors: Hou S,McCauley LK,Ma PX

    更新日期:2007-05-10 00:00:00

  • Collagen-polymer guidance of vessel network formation and stabilization by endothelial colony forming cells in vitro.

    abstract::Vessel morphogenesis is vital to regenerative medicine strategies. Here, collagen polymers, specified by intermolecular cross-link composition, are used to independently vary microstructure (fibril density, interfibril branching) and physical properties (stiffness) to guide 3D vessel network formation by endothelial c...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201300128

    authors: Whittington CF,Yoder MC,Voytik-Harbin SL

    更新日期:2013-09-01 00:00:00

  • A highly efficient siRNA carrier of PBLG modified hyperbranched PEI.

    abstract::In search for effective non-viral gene vectors for the delivery of siRNA, a copolymer was designed and synthesized by grafting hydrophobic poly(gamma-benzyl L-glutamate) segment (PBLG) to hyperbranched polyethylenimine (PEI-PBLG). PEI-PBLG could efficiently deliver siRNA to cells to silence the targeted gene. Markedly...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200900249

    authors: Chen J,Tian H,Guo Z,Xia J,Kano A,Maruyama A,Jing X,Chen X

    更新日期:2009-12-08 00:00:00

  • Mastoid obliteration using three-dimensional composite scaffolds consisting of polycaprolactone/β-tricalcium phosphate/collagen nanofibers: an in vitro and in vivo study.

    abstract::Two different composite scaffolds, solid-freeform-fabricated PCL/β-TCP supplemented with and without collagen nanofibers are fabricated. These scaffolds are evaluated whether a combination of collagen nanofibers with PCL/β-TCP can promote osteogenesis in a mastoid obliteration. To assess the effects of the cellular ac...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201200393

    authors: Jang CH,Cho YB,Yeo MG,Kim GH

    更新日期:2013-05-01 00:00:00

  • Reinforcing silk scaffolds with silk particles.

    abstract::Silk fibroin is a useful protein polymer for biomaterials and tissue engineering. In this work, porogen leached scaffolds prepared from aqueous and HFIP silk solutions were reinforced through the addition of silk particles. This led to about 40 times increase in the specific compressive modulus and the yield strength ...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200900358

    authors: Rajkhowa R,Gil ES,Kluge J,Numata K,Wang L,Wang X,Kaplan DL

    更新日期:2010-06-11 00:00:00

  • Enhanced efficacy of pluronic copolymer micelle encapsulated SCR7 against cancer cell proliferation.

    abstract::5,6-Bis(benzylideneamino)-2-mercaptopyrimidin-4-ol (SCR7) is a new anti cancer molecule having capability to selectively inhibit non-homologous end joining (NHEJ), one of the DNA double strand break (DSB) repair pathways inside the cells. In spite of the promising potential as an anticancer agent, hydrophobicity of SC...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201400480

    authors: John F,George J,Vartak SV,Srivastava M,Hassan PA,Aswal VK,Karki SS,Raghavan SC

    更新日期:2015-04-01 00:00:00

  • Polymers for the cell-specific immobilisation of megakaryocytic cell lines.

    abstract::Primary human megakaryocytes, the precursor cells of platelets, are difficult to collect and cultivate. Polymers that enrich these cells without affecting their regulation or function are of interest for basic research as well as for cord blood transplantation purposes since co-transplantation of enriched megakaryocyt...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201200368

    authors: Hansen A,Corless S,Cleland A,Petrik J,Gilbert N,Bradley M

    更新日期:2013-04-01 00:00:00

  • Multiple-Level Porous Polymer Monoliths with Interconnected Cellular Topology Prepared by Combining Hard Sphere and Emulsion Templating for Use in Bone Tissue Engineering.

    abstract::A combination of hard sphere and high internal phase emulsion templating gives a platform for synthesizing hierarchically porous polymers with a unique topology exhibiting interconnected spherical features on multiple levels. Polymeric spheres are fused by thermal sintering to create a 3D monolithic structure while an...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201700306

    authors: Paljevac M,Gradišnik L,Lipovšek S,Maver U,Kotek J,Krajnc P

    更新日期:2018-02-01 00:00:00

  • Extracellular matrix-like surfactant polymers containing arginine-glycine-aspartic acid (RGD) peptides.

    abstract::We report on a novel series of biomimetic polymers exhibiting interfacial properties similar to the extracellular matrix. A series of well-defined surfactant polymers were synthesized by simultaneously incorporating arginine-glycine-aspartic acid (RGD) peptide, dextran oligosaccharide, and hexyl ligands with controlle...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200300125

    authors: Anderson EH,Ruegsegger MA,Murugesan G,Kottke-Marchant K,Marchant RE

    更新日期:2004-08-09 00:00:00

  • A New Antimicrobial Agent: Poly (3-hydroxybutyric acid) Oligomer.

    abstract::In this work, it is first reported that the poly (3-hydroxybutyric acid) (PHB) oligomer with a few degrees of polymerization possesses effective antibacterial and antifungal properties. Two preparation methods for the PHB oligomer are described, namely, one-step ring-opening polymerization of β-butyrolactone and extra...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201800432

    authors: Ma L,Zhang Z,Li J,Yang X,Fei B,Leung PHM,Tao X

    更新日期:2019-05-01 00:00:00

  • Cellular uptake behavior of unfunctionalized and functionalized PBCA particles prepared in a miniemulsion.

    abstract::Fluorescent dye labeled unfunctionalized and functionalized poly(n-butylcyanoacrylate) nanoparticles were prepared using a miniemulsion technique. Amino acid and methoxyPEG functionalization could be introduced by using aqueous solutions as an initiator for the anionic polymerization in the heterophase. All the partic...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200700046

    authors: Weiss CK,Lorenz MR,Landfester K,Mailänder V

    更新日期:2007-07-09 00:00:00

  • Improved anti-inflammatory and pharmacokinetic properties for superoxide dismutase by chemical glycosidation with carboxymethylchitin.

    abstract::O-carboxymethylchitin (molecular weight = 1.07 x 10(5), degree of carboxymethylation = 80%, degree of N-acetylation = 91%) was chemically attached to superoxide dismutase by the formation of amide linkages through a carbodiimide catalyzed reaction. The glycosidated enzyme contained about 1.8 mole of polysaccharide per...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200400114

    authors: Valdivia A,Perez Y,Dominguez A,Caballero J,Gomez L,Schacht EH,Villalonga R

    更新日期:2005-02-23 00:00:00

  • Probing the Mucoadhesive Interactions Between Porcine Gastric Mucin and Some Water-Soluble Polymers.

    abstract::This study investigates the structural features of porcine gastric mucin (PGM) in aqueous dispersions and its interactions with water-soluble polymers (poly(acrylic acid) (PAA), poly(methacrylic acid) (PMAA), poly(ethylene oxide), and poly(ethylene glycol)) using isothermal titration calorimetry, turbidimetric titrati...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201500158

    authors: Albarkah YA,Green RJ,Khutoryanskiy VV

    更新日期:2015-11-01 00:00:00

  • Isolation and structure determination of complexed poly(3-hydroxyalkanoate) from beet (Beta vulgaris L.).

    abstract::Complexed poly(3-hydroxyalkanoate)s (cPHAs), one of two types of natural PHAs, occur in both prokaryotes and eukaryotes as a complex with biomacromolecules and could be involved in various physiological functions. In this study, a cPHA-component derived from a complex with calcium polyphosphate was isolated from sugar...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200500111

    authors: Suzuki Y,Esumi Y,Koshino H,Doi Y

    更新日期:2005-09-16 00:00:00

  • Polysaccharide Based Hemostatic Strategy for Ultrarapid Hemostasis.

    abstract::Bleeding complications usually cause significant morbidity and mortality in civilian and military populations. In clinical application, hemostatic sponges, gauzes, hydrogel, and bandages are widely used as the traditional effective hemostatic products for hemorrhage. However, the traditional hemostatic devices or agen...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章,评审

    doi:10.1002/mabi.201900370

    authors: Chen Y,Wu L,Li P,Hao X,Yang X,Xi G,Liu W,Feng Y,He H,Shi C

    更新日期:2020-04-01 00:00:00

  • The Pentablock Amphiphilic Copolymer T1107 Prevents Aggregation of Denatured and Reduced Lysozyme.

    abstract::Aggregation of denatured or unfolded proteins establishes a large energy barrier to spontaneous recovery of protein form and function following traumatic injury, tissue cryopreservation, and biopharmaceutical storage. Some tissues utilize small heat shock proteins (sHSPs) to prevent irreversible aggregation, which all...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.201600217

    authors: Poellmann MJ,Sosnick TR,Meredith SC,Lee RC

    更新日期:2017-02-01 00:00:00

  • Mechanical reinforcement of continuous flow spun polyelectrolyte complex fibers.

    abstract::A simple continuous flow wet-spinning method to achieve mechanical reinforcement of the two oppositely charged biopolymers chitosan and gellan gum is described. The mechanical properties of these biopolymers are influenced by the order of addition. Using a facile method for mechanical reinforcement of gellan gum/chito...

    journal_title:Macromolecular bioscience

    pub_type: 杂志文章

    doi:10.1002/mabi.200800257

    authors: Granero AJ,Razal JM,Wallace GG,in het Panhuis M

    更新日期:2009-04-08 00:00:00