Abstract:
:The impedance measured in a strip of heart tissue from the moth Hyalophora cecropia is fitted by circuit models of several configurations. The circuits include: (a) a single R-C circuit (b) a double R-C circuit (c) terminated transmission lines, and (d) a pattern of cells with cell-to-cell transmission paths. The last of these is found to give the best fit. Calculation of the model impedances and optimization of element values are performed by a computer. The possibility that the mechanism of cell-to-cell transmission may be capacitative rather than conductive is explored using values of capacitance derived from the circuit models to calculate the effect of capacitative coupling alone on signal transmission. The calculations show that sufficient voltage can be transmitted from the excited cell to an adjacent cell to effect excitation.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Stibitz GR,McCann FVdoi
10.1016/S0006-3495(74)70001-7subject
Has Abstractpub_date
1974-02-01 00:00:00pages
75-98issue
2eissn
0006-3495issn
1542-0086pii
S0006-3495(74)70001-7journal_volume
14pub_type
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更新日期:2014-01-07 00:00:00