Abstract:
AIMS:Both clinical and neurophysiologic testing of the penilo-cavernosus reflex is used in clinical practice. The aim of the present study was to determine the as yet unestablished potential contribution of sacral reflex testing to the diagnostic evaluation of patients with suspected neuropathic sacral lesions. METHODS:Fifty-three men with clinical, electrodiagnostic, and radiologic signs of chronic cauda equina or conus medullaris lesions were studied. Clinical examination, including assessment of anal sphincter tone and perianal sensation, and both clinical and neurophysiologic testing of the penilo-cavernosus reflex, were performed. The sacral reflex was elicited on a single (normal latency: <39.4 msec) and double (<36.0 msec) electrical, and on mechanical stimulation (<35.5 msec). Responses were recorded by a concentric needle electrode inserted consecutively into the left and right bulbocavernosus muscles. The response from the more abnormal side was further analyzed. RESULTS:Clinical testing of the penilo-cavernosus reflex was abnormal in 81% of patients with normal anal squeeze, in 78% with normal perianal sensation, and in 50-67% with bilaterally normal neurophysiologic findings on three different stimulation techniques. Neurophysiologic testing of the reflex was abnormal in 69-94% of patients with normal anal squeeze, in 56-67% with normal perianal sensation, and in 44-67% of patients with a clinically normal reflex. CONCLUSIONS:The study supported the clinical utility of both clinical and neurophysiologic measurement of the penilo-cavernosus reflex.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Podnar Sdoi
10.1002/nau.20520subject
Has Abstractpub_date
2008-01-01 00:00:00pages
399-402issue
5eissn
0733-2467issn
1520-6777journal_volume
27pub_type
杂志文章abstract:INTRODUCTION:The terminology for anorectal dysfunction in women has long been in need of a specific clinically-based Consensus Report. METHODS:This Report combines the input of members of the Standardization and Terminology Committees of two International Organizations, the International Urogynecological Association (...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23055
更新日期:2017-01-01 00:00:00
abstract:AIMS:To measure transient receptor potential vanilloid type 1 (TRPV1) signaling in human bladder urothelial cells (BUC) from non-neurogenic overactive bladder (OAB) patients and control subjects (NB) BUC. MATERIALS AND METHODS:Primary BUC cell cultures were derived from cystoscopic biopsies from two OAB and two NB sub...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21045
更新日期:2011-04-01 00:00:00
abstract:AIMS:We studied preoperative and postoperative pressure transmission ratio (PTR) and urethral pressure profilometry in patients undergoing the vaginal wall patch sling technique as a first surgical approach for genuine stress incontinence (GSI) with urethral hypermobility. The specific aims were to determine the exact ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20051
更新日期:2005-01-01 00:00:00
abstract:AIMS:To test the different formulae to calculate the bladder volume using ultrasound; the accuracy of patients hearing/feeling "bubbles" at the end of urodynamics testing as a measure of being empty; and how good we are at estimating PVR using X-ray at the end of video urodynamics testing. METHODS:This was a prospecti...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23963
更新日期:2019-04-01 00:00:00
abstract::Anticholinergics are commonly used for the treatment of frequency, urgency, and urge incontinence in women. Alpha-blockers have been shown to have a modulating effect on bladder smooth muscle but are not commonly used clinically for this indication. To evaluate the clinical effectiveness of each treatment as well as t...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1520-6777(1998)17:1<31::aid-nau6>3.0
更新日期:1998-01-01 00:00:00
abstract:AIMS:To evaluate the long term outcome, to review the complication ratio and to analyze predicting factors of catheterizable continent vesicostomy in an adult population. To deduct a proper patient counseling policy. METHODS:We identified all patients that underwent a continent vesicostomy between 1998 and 2008. We di...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20699
更新日期:2009-01-01 00:00:00
abstract:AIM:To linguistically validate the translation of the Lower Urinary Tract Symptoms (LUTS) Tool from English to 10 European languages and assess whether the translations adequately reflected the concepts in the original version and if urological terms and the individual items were readily understood. METHODS:Residents ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22265
更新日期:2013-01-01 00:00:00
abstract:AIMS:To investigate the functional outcome after supratrigonal cystectomy and augmentation ileocystoplasty in adult patients with refractory neurogenic lower urinary tract dysfunction (NLUTD). METHODS:Retrospective follow-up investigation in a single spinal cord injury rehabilitation center. In 29 patients, urodynamic...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22709
更新日期:2016-02-01 00:00:00
abstract:AIMS:To compare the effects of polypropylene mesh or porcine dermal acellular collagen matrix mesh with and without estradiol supplementation on vaginal smooth muscle cells (VaSMC) proliferation. RESULTS:Under in vitro culture conditions, VaSMC proliferation was significantly higher in the porcine dermal acellular col...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21064
更新日期:2011-03-01 00:00:00
abstract:AIMS:Our purpose was to explore the involvement of cognition in voluntary and involuntary pelvic floor muscle (PFM) contraction in stress urinary incontinent women. METHODS:PFM contraction monitored by surface electromyography (EMG) was measured without a mental distraction task (DT), and with a DT called "paced audit...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章
doi:10.1002/nau.23936
更新日期:2019-03-01 00:00:00
abstract:AIM:Treatments targeting vanilloid receptor TRPV1 are effective in some bladder disorders. Our aim was to determine the expression profiles of TRPV1 in regions of human bladder and test the hypothesis that there would be an upregulation of TRPV1 in mucosa of patients with bladder hypersensitivity but not idiopathic det...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20326
更新日期:2007-01-01 00:00:00
abstract:AIMS:This article aims to identify quality control (QC) best practice, to review published QC audits in order to identify how closely good practice is followed, and to carry out a market survey of the software features that support QC offered by urodynamics machines available in the UK. METHODS AND RESULTS:All UK dist...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.21133
更新日期:2011-11-01 00:00:00
abstract:AIM:To characterize purinergic signaling in overactive bladder (OAB). METHODS:Mucosal biopsies were taken by flexible cystoscopy from patients with storage symptoms referred to Urology Departments of collaborating hospitals. Immunohistochemistry (n = 12) and Western blot analysis (n = 28) were used to establish the qu...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24322
更新日期:2020-03-01 00:00:00
abstract:AIMS:Few studies have documented the effectiveness of continence promotion programs targeting older incontinent women. We sought to evaluate the impact of an interactive continence workshop on changing participants' attitudes, knowledge and skills in relation to self-managing or seeking care for incontinence. METHODS:...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20800
更新日期:2010-04-01 00:00:00
abstract:AIMS:To assess the different treatment methods in management of neurogenic bladder (NGB) in patients with Parkinson's disease (PD). METHODS:A systematic search was performed in Cochrane library, EMBASE, Proquest, Clinicaltrial.gov, WHO, Google Scholar, MEDLINE via PubMed, Ovid, ongoing trials registers, and conference...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23869
更新日期:2019-01-01 00:00:00
abstract:AIM:To examine the temporal effects of diabetes on the bladder and the external urethral sphincter (EUS) activity in rats. METHODS:Female Sprague-Dawley rats (n = 24) were divided into two groups: streptozotocin-induced diabetic rats and age-matched controls. Cystometrograms (CMGs) were taken under urethane anesthesia...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20543
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Stakeholders from around the world came together to address the unmet needs of underactive bladder (UAB) at the 3rd International Congress for Underactive Bladder. METHODS:The main recommendation from the regulatory working group is a need for a meeting of UAB stakeholders and regulatory agencies i...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23738
更新日期:2018-11-01 00:00:00
abstract:AIM:To describe how the use of new and established animal models and methods can generate vital and far reaching experimental data in the study of mechanism underlying neurogenic bladder overactivity. METHODS:Bladder and colonic irradiated mice and those with upper and lower motor neuron lesions were used to study neu...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.21120
更新日期:2011-06-01 00:00:00
abstract:AIMS:To systematically assess all available evidence on efficacy and safety of vanilloids for treating neurogenic lower urinary tract dysfunction (NLUTD) in patients with multiple sclerosis (MS). METHODS:This systematic review and meta-analysis was performed according to the Preferred Reporting Items for Systematic Re...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,meta分析,实务指引
doi:10.1002/nau.23314
更新日期:2018-01-01 00:00:00
abstract:AIMS:Prenatal myelomeningocele (MMC) repair has been proven to significantly reduce the need for hydrocephalus shunting and improve lower-extremity motor outcomes. The aim of this study was to evaluate the effect of prenatal MMC repair on the urological outcome. METHODS:All patients who underwent fetal MMC repair at o...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23174
更新日期:2017-08-01 00:00:00
abstract:AIMS:To obtain improved assessment of bladder sensitivity during cystometry by using a 10 cm visual analogue scale (VAS), and comparing it with the standard method according to the International Continence Society (ICS). METHODS:Twenty-five patients with presumed normal bladder functioning underwent filling cystometri...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/nau.20301
更新日期:2007-01-01 00:00:00
abstract:AIMS:The experiences and information needs of clinicians who use pelvic floor muscle training to manage urinary incontinence were explored. METHODS:Qualitative methods were used to conduct thematic analysis of data collected from clinician focus groups and interviews. Participants were registered physiotherapists and ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23716
更新日期:2018-11-01 00:00:00
abstract:AIMS:To investigate the use of an inflatable perile cuff to obstruct flow progressively during voiding in order to provide a noninvasive measure of bladder pressure. METHODS:In this study, we explain the observed relationship of flow rate with applied cuff pressure by analogy with a simple physical model. The model co...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10059
更新日期:2003-01-01 00:00:00
abstract:AIMS:The purpose of this study was to investigate efficacy, safety, and impact on quality of sleep of staggered furosemide and desmopressin in the treatment of nocturia in the elderly. METHODS:Patients aged >60 years with nocturia at least two voids per night were screened for enrollment into the study. A 3-week dose-...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.20986
更新日期:2011-03-01 00:00:00
abstract:AIMS:To determine the role of p75 neurotrophin receptor (p75NTR ) and the therapeutic effect of the selective small molecule p75NTR modulator, LM11A-31, in spinal cord injury (SCI) induced lower urinary tract dysfunction (LTUD) using a mouse model. METHODS:Adult female T8 -T9 transected mice were gavaged daily with LM...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23722
更新日期:2018-11-01 00:00:00
abstract::Estrogens are known to have a major role in the function of the lower urinary tract although the role of exogenous estrogen replacement therapy in the management of women with lower urinary tract dysfunction remains controversial. Whilst for many years systemic and vaginal estrogen therapy was felt to be beneficial in...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.22464
更新日期:2014-09-01 00:00:00
abstract:AIMS:Reflex bladder activation and inhibition by electrical stimulation of pudendal nerve (PN) afferents is a promising approach to restore control of bladder function in persons with lower urinary tract dysfunction caused by disease or injury. The objective of this work was to determine whether bladder activation evok...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22822
更新日期:2016-11-01 00:00:00
abstract:AIMS:To estimate the frequency of double incontinence, and to identify associated risk factors during pregnancy and postpartum in previously continent nulliparous women. METHODS:A cohort study in healthy, nulliparous, continent pregnant women, attending the public healthcare system of Catalonia (Spain) was designed. T...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22249
更新日期:2012-11-01 00:00:00
abstract:AIMS:The aim of this paper is to stablish de position of the Ibero-American Society of Neurourology and Urogynecology (SINUG) in relation to the use of suburethral meshes for the surgical treatment of female stress incontinence. METHODS:Tension-free mid-urethral slings (MUS) have become the most popular procedure for ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,实务指引
doi:10.1002/nau.24178
更新日期:2020-01-01 00:00:00
abstract:AIMS:Sacral nerve stimulation (SNS) is FDA approved as second-line therapy for both urinary and bowel control. However, there is limited evidence regarding long term safety. We determined adverse events associated with SNS among Medicare beneficiaries. METHODS:We used the 5% national random sample of Medicare claims f...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22618
更新日期:2015-09-01 00:00:00