Abstract:
AIMS:To compare the effects of polypropylene mesh or porcine dermal acellular collagen matrix mesh with and without estradiol supplementation on vaginal smooth muscle cells (VaSMC) proliferation. RESULTS:Under in vitro culture conditions, VaSMC proliferation was significantly higher in the porcine dermal acellular collagen matrix mesh exposed cells compared to the type I polypropylene mesh exposed cells (relative cell number, mean ± SD, 0.27 ± 0.03 vs. 0.21 ± 0.01, P = 0.03). Under estradiol supplementation cell proliferation in the porcine mesh exposed cells remained significantly higher compared to the polypropylene mesh exposed cells (relative cell number, mean ± SD, 0.27 ± 0.04 vs. 0.15 ± 0.03, P < 0.01). CONCLUSION:The decreased rate of erosion found with the utilization of biological absorbable mesh in vaginal reconstructive surgery may partially be explained by the significantly increased VaSMC proliferation with porcine dermal acellular collagen mesh compared to polypropylene mesh.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Gualtieri M,Zhang Y,Candiotti K,Yavagal S,Medina CA,Takacs Pdoi
10.1002/nau.21064subject
Has Abstractpub_date
2011-03-01 00:00:00pages
435-7issue
3eissn
0733-2467issn
1520-6777journal_volume
30pub_type
杂志文章abstract:AIMS:In the bladder, ATP is an important signaling molecule, which is released by bladder stretch and acid. We hypothesized that ATP might play a unique role in patients with OAB, characterized by low bladder volumes at first desire to void (FDV) and maximal cystometric capacity (MCC) and symptoms of frequency/urgency ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22344
更新日期:2013-09-01 00:00:00
abstract:AIM:The aim was to evaluate the voiding function over time after the TVT procedure for stress incontinence. MATERIALS AND METHODS:Thirty-eight women with urodynamic stress urinary incontinence were included in the study. For voiding function assessment the patients were asked if voiding had changed postoperatively, an...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20401
更新日期:2007-01-01 00:00:00
abstract:AIMS:To examine whether isolated bladder outlet obstruction in the absence of associated lower urinary tract abnormality results in hydronephrosis. Isolated obstruction causes a brief rise in bladder pressure that might not trigger hydronephrosis. METHODS:Data included adult men who underwent urodynamics for refractor...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24495
更新日期:2020-11-01 00:00:00
abstract:AIM:We present the surgical management and outcomes of patients who underwent transvaginal neo-bladder vaginal fistula (NBVF) repair at our institution. METHODS:Between 2002 and 2012, eight patients underwent transvaginal NBVF repair. The surgical management entailed placing a Foley catheter into the fistula tract. A ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22687
更新日期:2016-01-01 00:00:00
abstract:AIMS:The neuropathophysiology of a debilitating chronic urologic pain condition, bladder pain syndrome (BPS), remains unknown. Our recent data suggests withdrawal of cardiovagal modulation in subjects with BPS, in contrast to sympathetic nervous system dysfunction in another chronic pelvic pain syndrome, myofascial pel...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23995
更新日期:2019-06-01 00:00:00
abstract::This study was conducted to evaluate whether passive urethral resistance, detrusor internal work, and detrusor external work are independent measures of the voiding process. Passive urethral resistance, detrusor internal work, detrusor external work, and detrusor total work of 5 canines were determined under nonobstru...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(SICI)1520-6777(1996)15:5<529::AID-NAU9>3.
更新日期:1996-01-01 00:00:00
abstract:AIMS:No one has assessed urodynamic studies (UDS) to determine those steps that elicit the greatest anxiety, distress, and pain in children. We sought to systematically evaluate a child's UDS experience to mollify these reactions. METHODS:Prospective study involving children aged ≥5 undergoing UDS over a 6-month perio...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24339
更新日期:2020-04-01 00:00:00
abstract:AIMS:To study the influence of bladder pumping on the urinary bladder in 44 female rats. METHODS:Under halothane anesthesia, a urethral catheter was inserted into the bladder of 27 rats, and air (0.4-0.8 mL) was pumped in and out of the bladder at 0.5 cycles/second for a period of 5 minutes. Twenty-four hours after pu...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10048
更新日期:2002-01-01 00:00:00
abstract:AIM:To determine the psychometric properties of the total Vaizey score and its individual items. METHODS:The study was conducted as part of a prospective cohort study assessing the outcome of pelvic floor rehabilitation in patients with fecal incontinence. RESULTS:One hundred ninety-four patients were analyzed, 53 of...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20758
更新日期:2010-03-01 00:00:00
abstract:AIMS:We studied preoperative and postoperative pressure transmission ratio (PTR) and urethral pressure profilometry in patients undergoing the vaginal wall patch sling technique as a first surgical approach for genuine stress incontinence (GSI) with urethral hypermobility. The specific aims were to determine the exact ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20051
更新日期:2005-01-01 00:00:00
abstract::Intrinsic sphincter deficiency (ISD) is frequently treated with collagen bulking at the bladder neck. The standard material used, Contigen, biodegrades over 3-19 months requiring repeated injections to maintain efficacy. The study objective was to evaluate use of autologous ear chondrocytes for treatment of ISD. Women...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/1520-6777(2001)20:2<157::aid-nau18>3.0.co;
更新日期:2001-01-01 00:00:00
abstract:AIMS:In a previous study we observed impaired smooth muscle in the uterosacral ligament (USL) of patients with pelvic organ prolapse. The aims of the study were to describe the method of the novel microperfusion system and to determine normal function and pharmacology of smooth muscle in the USL. METHODS:Samples from ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22245
更新日期:2012-11-01 00:00:00
abstract::This study investigated the effects of outlet obstruction on blood flow and high energy phosphates content in the rabbit urinary bladder. Mild bladder outlet obstruction was induced by placing a silicon ring (diameter 7 mm) around the bladder neck of each male New Zealand White rabbit (n = 7). Before and immediately a...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930140309
更新日期:1995-01-01 00:00:00
abstract::The mechanism by which the ureteropelvic junction (UPJ) regulates the passage of urine from the renal pelvis to the ureter, and prevents urinary backflow from the the ureter to the renal pelvis, is not completely understood. The current communication studies this mechanism in 18 dogs. With the dogs under anesthesia, n...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(1997)16:4<315::aid-nau7>3.
更新日期:1997-01-01 00:00:00
abstract:AIMS:The prevalence rate of severe fecal incontinence (FI) in adults with spina bifida (SB) is high. The physiological basis of FI in SB has not been clearly established, which contributes to inadequate care. The aim was to better characterize a large cohort of adults with special consideration of anorectal physiology....
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23417
更新日期:2018-03-01 00:00:00
abstract:AIM:To elucidate the precise cellular and molecular mechanisms that underlie urethral fibrogenesis. METHODS:Endoluminal electrocautery injury (using Karl Storz 10 Fr. Pediatric urethroscope) was employed in male rabbits (n = 6) to create mucosal injury. Retrograde urethrogram (RUG) and endoluminal ultrasound technique...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24281
更新日期:2020-02-01 00:00:00
abstract::Published data on the safety and efficacy of finasteride in the treatment of benign prostatic hyperplasia are studied and compared with published conclusions. The need for publishing correlation studies of both the benefits and side-effects, to allow for informed physician and patient decisions, is detailed. ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930140603
更新日期:1995-01-01 00:00:00
abstract:AIMS:Prostate cancer is the most frequently diagnosed male cancer and urinary incontinence represents a major consequence following surgery. Penile compression clamps (PCCs) which externally occlude the urethra may be used to manage the incontinence. Despite potential complication of PCCs, such as deformation-inflicted...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23172
更新日期:2017-08-01 00:00:00
abstract:AIMS:To evaluate the feasibility and reliability of current perception threshold (CPT) measurement for sensory assessment of distinct locations in the male lower urinary tract (LUT). METHODS:Twelve male subjects (>18 years) without LUT symptoms or medical comorbidities were eligible. CPTs were determined twice (interv...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22956
更新日期:2017-02-01 00:00:00
abstract::The mammalian TRP family consists of 28 channels that can be subdivided into 6 different classes: TRPV (vanilloid), TRPC (canonical), TRPM (Melastatin), TRPP (Polycystin), TRPML (Mucolipin), and TRPA (Ankyrin). TRP channels are activated by a diversity of physical (voltage, heat, cold, mechanical stress) or chemical (...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.20511
更新日期:2008-01-01 00:00:00
abstract:AIMS:To assess the feasibility of a randomized controlled trial of a home-based integrated physical exercise and bladder-training program vs usual care in community-dwelling women with urinary incontinence (UI). METHODS:We conducted a parallel arm, nonblinded, pilot randomized controlled trial of a home-based integrat...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.23999
更新日期:2019-06-01 00:00:00
abstract:AIMS:The purpose of this study was to adapt the IIQ-7 to suit the Egyptian culture and then to assess validity and reliability of the adapted and translated IIQ-7 and UDI-6. METHODS:IIQ-7 was modified to suit Egyptian culture. Linguistic validation of the two questionnaires was done. Initial test-retest reliability an...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20609
更新日期:2009-01-01 00:00:00
abstract:AIMS:Lower urinary tract dysfunctions (LUTD) are very common in Multiple Sclerosis (MS), have a significant social impact, while the organic impact is discussed. We studied urinary complications and their risk factors in our cohort of MS patients, in order to improve the management of LUTD in MS. METHODS:Between 2004 ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22495
更新日期:2015-01-01 00:00:00
abstract:AIMS:We examined the mechanism of action of naftopidil, an α1D/A blocker, on spinal descending serotonergic neurotransmission for the micturition reflex. METHODS:We examined (1) urinary 5-hydroxyindole acetic acid (5-HIAA) after intraperitoneal administration of saline, para-chlorophenylalanine (PCPA; a serotonin synt...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23028
更新日期:2017-03-01 00:00:00
abstract:AIMS:Bladder wall stretch increases tissue tension and releases adenosine 5'-triphosphate (ATP) as part of a transduction process to sense bladder filling. Aging is associated with bladder fibrosis to produce a stiffer bladder wall: this may augment ATP release and contribute to age-dependent urgency. Muscarinic agonis...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24426
更新日期:2020-08-01 00:00:00
abstract:AIMS:Vaginal distention (VD) is a validated model of birth-related trauma in rats. Recently a mouse VD model was reported. Our study was originally conducted to evaluate the impact of age on VD in mice. This manuscript describes the study and reports on the lack of reproducibility of VD models in mice. METHODS:We util...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23886
更新日期:2019-02-01 00:00:00
abstract:AIMS:To investigate the use of an inflatable perile cuff to obstruct flow progressively during voiding in order to provide a noninvasive measure of bladder pressure. METHODS:In this study, we explain the observed relationship of flow rate with applied cuff pressure by analogy with a simple physical model. The model co...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10059
更新日期:2003-01-01 00:00:00
abstract:AIM:To determine the importance and contribution of compliance in a pelvic muscle exercise program as a factor in reducing the severity of urinary stress incontinence amongst Chinese women. METHODS:Two hundred fourteen women presenting with urinary stress incontinence who agreed to undertake a program of pelvic muscle...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章
doi:10.1002/nau.10110
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:The objective of our study was to investigate the prevalence and risk of developing stress urinary incontinence (SUI) in each type of high-intensity sport, and the associated impact on quality of life in sportswomen. METHODS:This cross-sectional study was conducted between March and November 2016. The study ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23538
更新日期:2018-08-01 00:00:00
abstract:AIMS:SYNERGY II was a 12-month phase III trial in patients with overactive bladder (OAB) symptoms that investigated the safety and efficacy of the combination of mirabegron and solifenacin in comparison with each monotherapy. This analysis evaluated the trial findings using four age subgroups (<65, ≥65, <75, and ≥75 ye...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.23919
更新日期:2019-02-01 00:00:00