Is isolated bladder outlet obstruction associated with hydronephrosis? A database analysis.

Abstract:

AIMS:To examine whether isolated bladder outlet obstruction in the absence of associated lower urinary tract abnormality results in hydronephrosis. Isolated obstruction causes a brief rise in bladder pressure that might not trigger hydronephrosis. METHODS:Data included adult men who underwent urodynamics for refractory non-neurogenic lower tract symptoms between 2011 and 2020. International Continence Society indices for obstruction (bladder outlet obstruction index [BOOI] ≥ 40) and underactivity (bladder contractility index [BCI] < 100) were calculated. Storage abnormality was defined as detrusor overactivity (DO) or poor compliance (<20 ml/cm H2 0). Isolated obstruction was defined as BOOI ≥ 40, BCI ≥ 100 and no storage abnormality. Nonparametric tests using R program (3.5.0) applied (p < .05 significant). Logistic regression analyses were performed to study the relationships of hydronephrosis with lower urinary tract function. RESULTS:A total 1596 men (range, 18-91 years; median, 51.0 years; Q3, 64.0 years; Q1, 34.0 years) were eligible. Hydronephrosis was noted in 274 (17.2%). A total of 45.4% were obstructed, 52.3% were underactive and 41.7% had storage abnormality. Storage abnormality (odds ratios [OR], 2.05; 95% confidence interval [CI]: 1.56, 2.69; p < .001) and bladder contractility (OR, 1.68; 95% CI, 1.25-2.26; p < .001) but not obstruction (OR, 1.07; 95% CI, 0.80-1.44; p = .634) was associated with hydronephrosis. Of eight possible combinations, men with BOO ≥ 40, BCI ≥ 100 and storage abnormality had highest probability of hydronephrosis (OR, 0.29; 95% CI, 0.24-0.33). Subanalysis showed that poor compliance (OR, 3.39; 95% CI, 2.49-4.60; p < .001) but not DO was associated with hydronephrosis. Younger age and higher postvoid residual urine were also associated with hydronephrosis. CONCLUSIONS:In adult men with refractory non-neurogenic lower urinary tract symptoms, isolated bladder outlet obstruction is not associated with hydronephrosis.

journal_name

Neurourol Urodyn

authors

Sinha S,Matai L

doi

10.1002/nau.24495

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

2361-2367

issue

8

eissn

0733-2467

issn

1520-6777

journal_volume

39

pub_type

杂志文章
  • Sensory function assessment of the human male lower urinary tract using current perception thresholds.

    abstract:AIMS:To evaluate the feasibility and reliability of current perception threshold (CPT) measurement for sensory assessment of distinct locations in the male lower urinary tract (LUT). METHODS:Twelve male subjects (>18 years) without LUT symptoms or medical comorbidities were eligible. CPTs were determined twice (interv...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22956

    authors: Knüpfer SC,Liechti MD,Gregorini F,De Wachter S,Kessler TM,Mehnert U

    更新日期:2017-02-01 00:00:00

  • Regeneration of detrusor muscle after subtotal cystectomy in the rat: effects on contractile proteins and bladder mechanics.

    abstract::The aim of the present study was to determine to what extent adult rats can produce new contracting bladder muscle and to see if such newly formed bladder tissue possesses characteristic mechanical properties or whether the ability to recover mechanically is so pronounced that the prehistory of the bladder is unimport...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.1020

    authors: Frederiksen H,Sjuve R,Arner A,Uvelius B

    更新日期:2001-01-01 00:00:00

  • Treatment decision-making among men with lower urinary tract symptoms: A qualitative study of men's experiences with recommendations for patient-centred practice.

    abstract:AIMS:To inform and guide patient-centred care for men with lower urinary tract symptoms (LUTS), by providing in-depth qualitative evidence regarding men's perspectives on treatment decision-making for LUTS. METHODS:An interview study of men recruited from 26 English urology departments. Purposive sampling captured sur...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.24533

    authors: Selman LE,Clement C,Ochieng CA,Lewis AL,Chapple C,Abrams P,Drake MJ,Horwood J

    更新日期:2020-10-14 00:00:00

  • Reproducing situationally triggered urgency incontinence in a controlled environment.

    abstract:INTRODUCTION:Patients with lower urinary tract symptoms often report urgency and incontinence episodes which are triggered by environmental scenarios, for example, "latch-key incontinence." To better understand the extent of this phenomenon, and how best to reduce its impact, we tested ways to recreate these situationa...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.24524

    authors: Clarkson BD,O Connell K,Conklin CA

    更新日期:2020-11-01 00:00:00

  • Differences in muscle activation patterns during pelvic floor muscle contraction and Valsalva maneuver.

    abstract:AIMS:To investigate the different muscle activation patterns around the abdomino-pelvic cavity in continent women and their effect on pressure generation during a correct pelvic floor muscle (PFM) contraction and a Valsalva maneuver. METHODS:Thirteen continent women were assessed. Abdominal, chest wall, and PFM activi...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20203

    authors: Thompson JA,O'Sullivan PB,Briffa NK,Neumann P

    更新日期:2006-01-01 00:00:00

  • Can persisting detrusor hyperreflexia be predicted after transurethral prostatectomy for benign prostatic hypertrophy?

    abstract::Detrusor hyperreflexia (DH) is frequently found in patients with benign prostatic hypertrophy (BPH) and persists in 30-50% of patients after successful removal of bladder neck obstruction by transurethral prostatectomy (TUR-P) or surgical enucleation of the prostate. It would be beneficial for surgeons to be able to i...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/(sici)1520-6777(2000)19:3<233::aid-nau4>3.

    authors: Kageyama S,Watanabe T,Kurita Y,Ushiyama T,Suzuki K,Fujita K

    更新日期:2000-01-01 00:00:00

  • Quality control in urodynamics and the role of software support in the QC procedure.

    abstract:AIMS:This article aims to identify quality control (QC) best practice, to review published QC audits in order to identify how closely good practice is followed, and to carry out a market survey of the software features that support QC offered by urodynamics machines available in the UK. METHODS AND RESULTS:All UK dist...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,评审

    doi:10.1002/nau.21133

    authors: Hogan S,Jarvis P,Gammie A,Abrams P

    更新日期:2011-11-01 00:00:00

  • T- and L-type calcium channels mediate alpha(1)-adrenoceptor-evoked contraction in the guinea-pig vas deferens.

    abstract:AIMS:The importance of the T- and L-type Ca(2+) channels on the alpha(1)-adrenoceptor-mediated contraction of guinea-pig vas deferens was investigated in relation to the SK and BK channels. METHODS:Isometric contractile response to electrical stimulation (ES) of 50 pulses at 40 Hz was recorded. ES responses were modul...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20654

    authors: Shishido T,Sakai S,Tosaka T

    更新日期:2009-01-01 00:00:00

  • Relationships among symptoms, bother, and treatment satisfaction in overactive bladder patients.

    abstract:AIMS:We have studied the association between various symptoms, bother, and patient treatment satisfaction in overactive bladder (OAB). METHODS:Episodes of urgency, incontinence, daytime frequency and nocturia and responses to the patient perception of bladder condition scale, the urgency perception scale, and visual a...

    journal_title:Neurourology and urodynamics

    pub_type: 临床试验,杂志文章

    doi:10.1002/nau.20367

    authors: Michel MC,Oelke M,Goepel M,Beck E,Burkart M

    更新日期:2007-01-01 00:00:00

  • Correlations between the ICIQ-SF score and urodynamic findings.

    abstract:AIMS:The primary aim of this prospective study was to examine the correlations between "The International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF)" score and urodynamic findings in patients with urge incontinence. In addition, we aimed to observe the alterations of these parameters with antimusca...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20389

    authors: Seckiner I,Yesilli C,Mungan NA,Aykanat A,Akduman B

    更新日期:2007-01-01 00:00:00

  • Treatment of daytime urinary incontinence: A standardization document from the International Children's Continence Society.

    abstract:PURPOSE:This article is a standardization document of the International Children's Continence Society (ICCS); it represent a consensus of ICCS on the management of pediatric daytime urine incontinence (DUI). MATERIALS AND METHODS:This document was designed and written by a multi-disciplinary core group of authors appo...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,评审

    doi:10.1002/nau.22911

    authors: Chang SJ,Van Laecke E,Bauer SB,von Gontard A,Bagli D,Bower WF,Renson C,Kawauchi A,Yang SS

    更新日期:2017-01-01 00:00:00

  • Ex vivo pharmacology of surgical samples of the uterosacral ligament. Part I: Effects of carbachol and oxytocin on smooth muscle.

    abstract:AIMS:In a previous study we observed impaired smooth muscle in the uterosacral ligament (USL) of patients with pelvic organ prolapse. The aims of the study were to describe the method of the novel microperfusion system and to determine normal function and pharmacology of smooth muscle in the USL. METHODS:Samples from ...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22245

    authors: Drews U,Renz M,Busch C,Reisenauer C

    更新日期:2012-11-01 00:00:00

  • Does ketamine ameliorate the social stress-related bladder dysfunction in mice?

    abstract:AIMS:The aim of this study is to investigate whether ketamine could relieve the social stress (SS)-related bladder dysfunction in mice. MATERIALS AND METHODS:The FVB mice were randomly assigned to either undergo SS exposure for 60 minutes per day on seven consecutive days for 4 weeks (SS1) or control without SS (SS0)....

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.24324

    authors: Yang SS,Chang HH,Chang SJ

    更新日期:2020-03-01 00:00:00

  • Clinical efficacy and safety of mirabegron and imidafenacin in women with overactive bladder: A randomized crossover study (the MICRO study).

    abstract:AIMS:We aimed to compare the efficacy and safety of mirabegron, a β3-adrenoceptor agonist, and imidafenacin, an anticholinergic agent, in overactive bladder patients. METHODS:We conducted a multicenter, prospective randomized cross-over study at 5 hospitals in Japan from December 2012 to June 2015. We enrolled female ...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/nau.23050

    authors: Torimoto K,Matsushita C,Yamada A,Goto D,Matsumoto Y,Hosokawa Y,Miyake M,Aoki K,Hirayama A,Tanaka N,Fujimoto K

    更新日期:2017-04-01 00:00:00

  • Inconclusive psychometric properties of the Vaizey score in fecally incontinent patients: a prospective cohort study.

    abstract:AIM:To determine the psychometric properties of the total Vaizey score and its individual items. METHODS:The study was conducted as part of a prospective cohort study assessing the outcome of pelvic floor rehabilitation in patients with fecal incontinence. RESULTS:One hundred ninety-four patients were analyzed, 53 of...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20758

    authors: Bols EM,Hendriks EJ,Deutekom M,Berghmans BC,Baeten CG,de Bie RA

    更新日期:2010-03-01 00:00:00

  • Genetic variants and expression changes in urgency urinary incontinence: A systematic review.

    abstract:AIM:To perform a systematic review summarizing the knowledge of genetic variants, gene, and protein expression changes in humans and animals associated with urgency urinary incontinence (UUI) and to provide an overview of the known molecular mechanisms related to UUI. METHODS:A systematic search was performed on March...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,评审

    doi:10.1002/nau.24512

    authors: Post WM,Ruiz-Zapata AM,Grens H,de Vries RBM,Poelmans G,Coenen MJH,Janssen DAW,Heesakkers JPFA,Oosterwijk E,Kluivers KB

    更新日期:2020-11-01 00:00:00

  • Prospective study comparing hyoscyamine, doxazosin, and combination therapy for the treatment of urgency and frequency in women.

    abstract::Anticholinergics are commonly used for the treatment of frequency, urgency, and urge incontinence in women. Alpha-blockers have been shown to have a modulating effect on bladder smooth muscle but are not commonly used clinically for this indication. To evaluate the clinical effectiveness of each treatment as well as t...

    journal_title:Neurourology and urodynamics

    pub_type: 临床试验,杂志文章

    doi:10.1002/(sici)1520-6777(1998)17:1<31::aid-nau6>3.0

    authors: Serels S,Stein M

    更新日期:1998-01-01 00:00:00

  • New concepts in relation to urge and detrusor activity.

    abstract::Investigations of micromotion characteristics of bladder wall strips and pressure wave phenomena in total bladders in vitro and in vivo indicate that micromotion phenomena occur in the bladder wall. Local contractions can occur without an increase in tension or pressure, because other parts are in antiphase. Local con...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.1930120504

    authors: Coolsaet BL,Van Duyl WA,Van Os-Bossagh P,De Bakker HV

    更新日期:1993-01-01 00:00:00

  • Pelviureteral inhibitory reflex and ureteropelvic excitatory reflex: role of the two reflexes in regulation of urine flow from the renal pelvis to the ureter.

    abstract::The mechanism by which the ureteropelvic junction (UPJ) regulates the passage of urine from the renal pelvis to the ureter, and prevents urinary backflow from the the ureter to the renal pelvis, is not completely understood. The current communication studies this mechanism in 18 dogs. With the dogs under anesthesia, n...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/(sici)1520-6777(1997)16:4<315::aid-nau7>3.

    authors: Shafik A

    更新日期:1997-01-01 00:00:00

  • Surgical anatomy of the dorsal nerve of the clitoris.

    abstract:AIMS:The purpose of this study was to describe the distal pathway of the dorsal nerve of the clitoris (DNC) from gross anatomical and histological studies of cadaver specimens. METHODS:We performed dissections on 14 intact adult cadaver vulva specimens using 2× loupe magnification and microscopy. The DNC was identifie...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20996

    authors: Ginger VA,Cold CJ,Yang CC

    更新日期:2011-03-01 00:00:00

  • A cross-sectional study of ultrasound estimated bladder weight in a sample of men and women without lower urinary tract symptoms.

    abstract:AIMS:A non-invasive ultrasound method of estimating bladder weight (UEBW) has been proposed as diagnostic for outflow tract obstruction and detrusor overactivity in men and women. There are no data on asymptomatic men and women. This study aimed to examine the relationship between UEBW, age, height, body mass index (BM...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20757

    authors: Morris V,Steventon N,Hazbun S,Wagg A

    更新日期:2009-01-01 00:00:00

  • Clinical and neurophysiologic testing of the penilo-cavernosus reflex.

    abstract:AIMS:Both clinical and neurophysiologic testing of the penilo-cavernosus reflex is used in clinical practice. The aim of the present study was to determine the as yet unestablished potential contribution of sacral reflex testing to the diagnostic evaluation of patients with suspected neuropathic sacral lesions. METHOD...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20520

    authors: Podnar S

    更新日期:2008-01-01 00:00:00

  • Assessing bladder capacity in children: is it feasible at all?

    abstract:AIM:The aim of the study was to assess correlations between body parameters and bladder capacity in healthy schoolboys and schoolgirls. On the basis of those anthropometric data functional bladder capacity (FBC) in children was estimated. MATERIALS AND METHODS:The questionnaires were sent to 1,055 parents of children ...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20123

    authors: Chrzan R,Czernik J,Apoznański W,Bagłaj M,Patkowski D

    更新日期:2006-01-01 00:00:00

  • A novel role for follistatin in hypersensitivity following cystitis.

    abstract:AIMS:Previous studies have shown that the activin-binding protein follistatin reduces inflammation in several mouse models of colitis. To determine whether follistatin also has a beneficial effect following bladder inflammation, we induced cystitis in mice using cyclophosphamide (CYP) and examined the relationship betw...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22941

    authors: Shaffer AD,Feng B,La JH,Joyce SC,Gebhart GF

    更新日期:2017-02-01 00:00:00

  • Exploratory factory analysis and predicted probabilities of a Chinese version of Dysfunctional Voiding Symptom Score (DVSS) questionnaire.

    abstract:AIMS:To evaluate the reliability, validity, and predicted probabilities of a Chinese version of the Dysfunctional Voiding Symptom Score (DVSS) and to explore the latent factors underlying dysfunctional voiding. MATERIALS AND METHODS:We enrolled 60 children (38 girls and 22 boys) with a diagnosis of dysfunctional voidi...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22254

    authors: Chang SJ,Chen TH,Su CC,Yang SS

    更新日期:2012-11-01 00:00:00

  • A computer model of the neural control of the lower urinary tract.

    abstract::Better understanding of the underlying working mechanism of the neural control of the lower urinary tract will facilitate the treatment of dysfunction with a neurogenic cause. We developed a computer model to study the effect of a neural control system on lower urinary tract behavior. To model the mechanical propertie...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/(sici)1520-6777(1998)17:3<175::aid-nau3>3.

    authors: van Duin F,Rosier PF,Rijkhoff NJ,van Kerrebroek PE,Debruyne FM,Wijkstra H

    更新日期:1998-01-01 00:00:00

  • Racial differences in female urethral morphology and levator hiatal dimensions: an ultrasound study.

    abstract:AIM:To compare the urethral sphincter morphology and levator hiatal dimensions between white and black premenopausal nulliparous asymptomatic women using 3D/4D translabial ultrasonography. METHODS:Nulliparous black and white women were recruited in a tertiary gynecological center. All women were completely asymptomati...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.21181

    authors: Derpapas A,Ahmed S,Vijaya G,Digesu GA,Regan L,Fernando R,Khullar V

    更新日期:2012-04-01 00:00:00

  • "We have to stop again?!": The impact of overactive bladder on family members.

    abstract:AIMS:Overactive bladder (OAB), characterized by urinary urgency, with or without incontinence, and urinary frequency and nocturia, has a significant impact on patients' lives. Given the social context inherent in OAB, the purpose of this study was to identify issues faced by OAB family members. METHODS:Incontinent OAB...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20705

    authors: Coyne KS,Matza LS,Brewster-Jordan J

    更新日期:2009-01-01 00:00:00

  • Involvement of Rho-kinase in the contractile mechanism of human ureteral smooth muscle.

    abstract:AIM:Even though many agents have been implicated as modulators of ureteral contractile activity, the exact mechanisms that control human ureteral smooth muscle contractility have yet to be clearly defined. Recently, Rho-kinase has been reported to be involved in the contractile mechanism of smooth muscles in various or...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20096

    authors: Hong SK,Kwak C,Chang Jeong B,Kim BS,Kim HH

    更新日期:2005-01-01 00:00:00

  • The vaginal vestibule: assessing the case for an anterior and posterior division.

    abstract::The vaginal vestibule has not been the subject of a dedicated journal article. Recent terminology has suggested its division into anterior and posterior components. The case for this division has not yet been assessed. Both components extend laterally from the hymen to the junction with the labia minora. The posterior...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.23064

    authors: Haylen BT,Fischer G,Vu D,Tse K

    更新日期:2017-04-01 00:00:00