Penile compression clamps: A model of the internal mechanical state of penile soft tissues.

Abstract:

AIMS:Prostate cancer is the most frequently diagnosed male cancer and urinary incontinence represents a major consequence following surgery. Penile compression clamps (PCCs) which externally occlude the urethra may be used to manage the incontinence. Despite potential complication of PCCs, such as deformation-inflicted tissue damage, to date, there are no reported biomechanical criteria for design of PCCs, in terms of quantitative parameters for evaluating the safety-versus-efficacy of existing or future designs. METHODS:We developed a set of computational three-dimensional models of the penis, to which compression was applied using five generic PCC designs. The internal mechanical states of the soft tissues of the penis were then analysed using finite element simulations. RESULTS:Stresses in skin, fat, and tunica albuginea regularly exceeded 10 kPa (75 mmHg). Cuff-type and knurl-type PCCs pose the highest potential risks to tissue health with elevated tissue stresses around the entire penile perimeter (cuff) or urethral stress concentrations (knurl). The soft and contoured PCCs produced the lowest values of these mechanical parameters. CONCLUSIONS:The present study identified design characteristics, including envelopment, adaptability, and durability which provide the safest mechanical conditions in the penis and thus minimize the risk of tissue damage while still managing incontinence. Such data should help to design a safer clamp.

journal_name

Neurourol Urodyn

authors

Levy A,Fader M,Bader D,Gefen A

doi

10.1002/nau.23172

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

1645-1650

issue

6

eissn

0733-2467

issn

1520-6777

journal_volume

36

pub_type

杂志文章
  • Preliminary results of a dose-finding study for botulinum toxin-A in patients with idiopathic overactive bladder: 100 versus 150 units.

    abstract:AIMS:To evaluate the clinical outcomes of two different doses of BTX-A in patients with I-OAB. METHODS:This investigator initiated, randomized trial was designed to evaluate clinical differences in outcomes for 100 versus 150 U BTX-A in patients with I-OAB. Patients with OAB-Wet and OAB-Dry were randomized to receive ...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/nau.20611

    authors: Cohen BL,Barboglio P,Rodriguez D,Gousse AE

    更新日期:2009-01-01 00:00:00

  • Can we improve our diagnosis of impaired detrusor contractility in women? An ICI-RS 2019 proposal.

    abstract:INTRODUCTION:Widely accepted consensus terminology and calculations of detrusor contractility in females do not exist but may be useful. We report the output of a proposal session at the International Consultation on Incontinence Research Society meeting 2019, addressing the title topic. METHODS:Three formal presentat...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,评审

    doi:10.1002/nau.24260

    authors: Smith PP,Valentini F,Mytilekas KV,Apostolidis A,Rademakers K,Cardozo L,Gammie A

    更新日期:2020-07-01 00:00:00

  • Measurement of total urethral compliance in females with stress incontinence.

    abstract::Urodynamic evaluation of stress incontinence has failed to result in consistent diagnostic parameters. Using retrospective female bladder pressure and urine flow data, we evaluated two parameters based on a conductance formula. This formula was derived from fitting a classical fluid dynamic equation to published data ...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.1930120311

    authors: Walter JS,Wheeler JS,Morgan C,Zaszczurynski P,Plishka M

    更新日期:1993-01-01 00:00:00

  • Oestrogens and overactive bladder.

    abstract::Estrogens are known to have a major role in the function of the lower urinary tract although the role of exogenous estrogen replacement therapy in the management of women with lower urinary tract dysfunction remains controversial. Whilst for many years systemic and vaginal estrogen therapy was felt to be beneficial in...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,评审

    doi:10.1002/nau.22464

    authors: Robinson D,Cardozo L,Milsom I,Pons ME,Kirby M,Koelbl H,Vierhout M

    更新日期:2014-09-01 00:00:00

  • Adherence to ICCS nomenclature guidelines in subsequent literature: a bibliometric study.

    abstract:AIMS:Since the publication of the 2006 International Children's Continence Society (ICCS) guidelines on terminologies for lower urinary tract dysfunction in children, little is known of their impact. In this study, we aim to quantify the adherence to the guidelines in the published literature, and to examine whether Me...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22341

    authors: Dannaway J,Ng H,Deshpande AV

    更新日期:2013-09-01 00:00:00

  • Expressions of urothelial functional proteins in idiopathic detrusor overactivity patients refractory to antimuscarinic therapy with different urodynamic characteristics.

    abstract:AIMS:This study investigated the expressions of PGP9.5, P2  X 3 , muscarinic receptor (M3) and beta-3 adrenoreceptor (AR) in idiopathic detrusor overactivity (IDO) patients refractory to antimuscarinic treatment, and analyzed the correlation between protein expressions and clinical symptoms of IDO bladders with differe...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.23138

    authors: Liu HT,Kuo HC

    更新日期:2017-06-01 00:00:00

  • Neuromuscular electrical stimulation and the treatment of lower urinary tract dysfunction in multiple sclerosis--a double blind, placebo controlled, randomised clinical trial.

    abstract:AIMS:Lower urinary tract dysfunction affects up to 75% of the multiple sclerosis population. Results from our recent Pilot Study (McClurg et al., 2006) indicated that a combined programme of pelvic floor muscle training, electromyography biofeedback and neuromuscular electrical stimulation modalities may alleviate some...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/nau.20486

    authors: McClurg D,Ashe RG,Lowe-Strong AS

    更新日期:2008-01-01 00:00:00

  • Obstruction enhances rho-kinase pathway and diminishes protein kinase C pathway in carbachol-induced calcium sensitization in contraction of α-toxin permeabilized guinea pig detrusor smooth muscle.

    abstract:AIMS:We investigated the relative important role of rho kinase (ROK) and protein kinase C (PKC) pathways in carbachol (CCh)-induced Ca(2+) sensitization in α-toxin permeabilized Guinea pig detrusor smooth muscle (DSM) following bladder outlet obstruction (BOO). METHODS:Bladder outlet obstruction was created by placeme...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.21193

    authors: Shahab N,Kajioka S,Takahashi-Yanaga F,Onimaru M,Matsuda M,Seki N,Naito S

    更新日期:2012-04-01 00:00:00

  • Is isolated bladder outlet obstruction associated with hydronephrosis? A database analysis.

    abstract:AIMS:To examine whether isolated bladder outlet obstruction in the absence of associated lower urinary tract abnormality results in hydronephrosis. Isolated obstruction causes a brief rise in bladder pressure that might not trigger hydronephrosis. METHODS:Data included adult men who underwent urodynamics for refractor...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.24495

    authors: Sinha S,Matai L

    更新日期:2020-11-01 00:00:00

  • The psychometric validation of the OAB family impact measure (OAB-FIM).

    abstract:AIMS:Although overactive bladder (OAB) impacts patient health-related quality of life, the impact of OAB on family members is not known. Presently, no validated instruments exist to assess family impact, thus we examined the psychometric properties of a new instrument, the overactive bladder family impact measure (OAB-...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20715

    authors: Coyne KS,Matza LS,Brewster-Jordan J,Thompson C,Bavendam T

    更新日期:2010-03-01 00:00:00

  • Bladder neck suspension for stress urinary incontinence: how does it work?

    abstract::The objective of this study was to compare urethral resistance as determined in pressure-flow studies before and after Burch retropubic urethropexy. Urethral resistance was retrospectively determined from pressure-flow studies in 178 patients before and 1 year after Burch retropubic urethropexy. Results of cotton swab...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/(sici)1520-6777(1999)18:6<623::aid-nau12>3

    authors: Klutke JJ,Klutke CG,Bergman J,Elia G

    更新日期:1999-01-01 00:00:00

  • Simultaneous in vivo comparison of water-filled and air-filled pressure measurement catheters: Implications for good urodynamic practice.

    abstract:AIMS:This study aimed to evaluate whether the pressure readings obtained from air-filled catheters (AFCs) are the same as the readings from simultaneously inserted water-filled catheters (WFCs). It also aimed to make any possible recommendations for the use of AFCs to conform to International Continence Society (ICS) G...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22827

    authors: Gammie A,Abrams P,Bevan W,Ellis-Jones J,Gray J,Hassine A,Williams J,Hashim H

    更新日期:2016-11-01 00:00:00

  • Effect of severity of urinary incontinence on quality of life in women.

    abstract:AIMS:While the effect of different types of incontinence on the quality of life (QoL) has been clearly documented, the information about the impact of incontinence severity on QoL in women is lacking. Therefore, we investigated whether increasingly severe degrees of incontinence were linearly correlated with poorer QoL...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.23568

    authors: Krhut J,Gärtner M,Mokris J,Horcicka L,Svabik K,Zachoval R,Martan A,Zvara P

    更新日期:2018-08-01 00:00:00

  • Comparison of voiding function and nociceptive behavior in two rat models of cystitis induced by cyclophosphamide or acetone.

    abstract:AIMS:Nociceptive behavior and its relationship with bladder dysfunction were investigated in two cystitis models, which were induced by intraperitoneal (i.p.) injection of cyclophosphamide (CYP) or intravesical instillation of acetone, using freely moving, non-catheterized conscious rats. METHODS:Female Sprague-Dawley...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20777

    authors: Saitoh C,Yokoyama H,Chancellor MB,de Groat WC,Yoshimura N

    更新日期:2010-03-01 00:00:00

  • Evaluation of combined therapeutic effects of hydrogen sulfide donor sodium hydrogen sulfide and phosphodiesterase type-5 inhibitor tadalafil on erectile dysfunction in a partially bladder outlet obstructed rat model.

    abstract:AIMS:To evaluate the impacts of hydrogen sulfide (H2 S) donor, sodium hydrogen sulfide (NaHS), and phosphodiesterase type-5 inhibitor (PDE5i), tadalafil per se and their combination treatment on partial bladder outlet obstruction (PBOO)-induced erectile dysfunction (ED). METHODS:Sprague-Dawley rats were equally divide...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.24333

    authors: Yilmaz-Oral D,Kaya-Sezginer E,Oztekin CV,Bayatli N,Lokman U,Gur S

    更新日期:2020-04-01 00:00:00

  • Pelvic floor dysfunction negatively impacts general functional performance in patients with multiple sclerosis.

    abstract:BACKGROUND:There is a lack of evidence to assess whether gait functionality can be affected by the condition of the pelvic floor musculature in patients with multiple sclerosis (MS). OBJECTIVE:To evaluate the relationship between pelvic floor functionality and general functional performance, and also their relationshi...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.24314

    authors: Aguilar-Zafra S,Del Corral T,Vidal-Quevedo C,Rodríguez-Durán P,López-de-Uralde-Villanueva I

    更新日期:2020-03-01 00:00:00

  • Co-activation of the abdominal and pelvic floor muscles during voluntary exercises.

    abstract::The response of the abdominal muscles to voluntary contraction of the pelvic floor (PF) muscles was investigated in women with no history of symptoms of stress urinary incontinence to determine whether there is co-activation of the muscles surrounding the abdominal cavity during exercises for the PF muscles. Electromy...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/1520-6777(2001)20:1<31::aid-nau5>3.0.co;2-

    authors: Sapsford RR,Hodges PW,Richardson CA,Cooper DH,Markwell SJ,Jull GA

    更新日期:2001-01-01 00:00:00

  • How to toilet train healthy children? A review of the literature.

    abstract:AIMS:To review the literature on toilet training (TT) in healthy children. METHODS:Through an extended literature search, all data on developmental signs of readiness for TT, TT methods, definitions of being toilet trained, TT problems, and predictive factors for success were reviewed. RESULTS:Specific studies on thi...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,评审

    doi:10.1002/nau.20490

    authors: Vermandel A,Van Kampen M,Van Gorp C,Wyndaele JJ

    更新日期:2008-01-01 00:00:00

  • Best practices for cystometric evaluation of lower urinary tract function in muriform rodents.

    abstract:AIMS:Rodent cystometry has provided valuable insights into the impact of the disease, injury, and aging on the cellular and molecular pathways, neurologic processes, and biomechanics of lower urinary tract function. The purpose of this white paper is to highlight the benefits and shortcomings of different experimental ...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.24415

    authors: Fraser MO,Smith PP,Sullivan MP,Bjorling DE,Campeau L,Andersson KE,Yoshiyama M

    更新日期:2020-08-01 00:00:00

  • Comparison of pelvic floor muscle training, electromyography biofeedback, and neuromuscular electrical stimulation for bladder dysfunction in people with multiple sclerosis: a randomized pilot study.

    abstract:AIM:Bladder dysfunction affects up to 90% of the multiple sclerosis (MS) population. Interventions such as Pelvic Floor Training and Advice (PFTA), Electromyography (EMG) Biofeedback, and Neuromuscular Electrical Stimulation (NMES) have received limited research attention within this population. This study aimed to det...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/nau.20209

    authors: McClurg D,Ashe RG,Marshall K,Lowe-Strong AS

    更新日期:2006-01-01 00:00:00

  • Prevalence of urinary incontinence and its association with multimorbidity in women aged 50 years or older: A population-based study.

    abstract:AIMS:To evaluate the prevalence and associated risk factors for urinary incontinence, as well as its association with multimorbidity among Brazilian women aged 50 or over. METHODS:This was a secondary analysis of a cross-sectional population-based study including 622 women 50 years or older, conducted in the city of C...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22679

    authors: Reigota RB,Pedro AO,de Souza Santos Machado V,Costa-Paiva L,Pinto-Neto AM

    更新日期:2016-01-01 00:00:00

  • Repetitive transcranial magnetic stimulation for chronic neuropathic pain in patients with bladder pain syndrome/interstitial cystitis.

    abstract:AIMS:To evaluate the efficacy, safety, and tolerability of repetitive Transcranial Magnetic Stimulation (rTMS) associated with standard drug therapies for neuropathic pain that does not respond to pharmacological treatment alone in patients with Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC). Secondary goals were...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/nau.23718

    authors: Cervigni M,Onesti E,Ceccanti M,Gori MC,Tartaglia G,Campagna G,Panico G,Vacca L,Cambieri C,Libonati L,Inghilleri M

    更新日期:2018-11-01 00:00:00

  • Diagnostic yield of cystoscopy in the evaluation of recurrent urinary tract infection in women.

    abstract:AIMS:Due to a paucity of evidence-based guidelines, anecdotal practice patterns often dictate clinical management of recurrent urinary tract infection (UTI) in women. Our aim was to identify pathologic findings of the urinary tract through cystoscopy and imaging in women with recurrent UTI, and to determine if specific...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22998

    authors: Pagano MJ,Barbalat Y,Theofanides MC,Edokpolo L,James MB,Cooper KL

    更新日期:2017-03-01 00:00:00

  • Short forms to assess life quality and symptom distress for urinary incontinence in women: the Incontinence Impact Questionnaire and the Urogenital Distress Inventory. Continence Program for Women Research Group.

    abstract::This article describes short form versions of the Incontinence Impact Questionnaire (IIQ) and the Urogenital Distress Inventory (UDI). These instruments assess life impact and symptom distress, respectively, of urinary incontinence and related conditions for women. All subsets regression analysis was used to find item...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.1930140206

    authors: Uebersax JS,Wyman JF,Shumaker SA,McClish DK,Fantl JA

    更新日期:1995-01-01 00:00:00

  • Electrical stimulation of sacral dermatomes can suppress aberrant urethral reflexes in felines with chronic spinal cord injury.

    abstract:AIMS:Uncoordinated reflex contractions of the external urethral sphincter (EUS) are a major component of voiding dysfunction after neurologic injury. Patterned stimulation of sacral afferent pathways can reduce abnormal EUS reflexes after acute spinal cord injury (SCI); however, effectiveness following chronic SCI is u...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22276

    authors: McCoin JL,Bhadra N,Gustafson KJ

    更新日期:2013-01-01 00:00:00

  • The effect of bladder sensation on uroflowmetry parameters in healthy young men.

    abstract:AIMS:To investigate the effect of the bladder sensation grade on uroflowmetry parameters. METHODS:Fifty healthy volunteering young men were enrolled in the present study. In total, three uroflowmetry evaluations were made. Qmax , Qave , VV, and PVR urine was obtained three times in three described bladder sensation gr...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.22762

    authors: Kaynar M,Kucur M,Kiliç O,Akand M,Gul M,Goktas S

    更新日期:2016-06-01 00:00:00

  • Long-term patient satisfaction following cadaveric pubovaginal sling incontinence surgery using the UDI and IIQ-7 questionnaires.

    abstract:AIMS:The goal of any incontinence surgery is overall long-term patient satisfaction. The purpose of our study was to assess long-term patient satisfaction following cadaveric fascia lata pubovaginal sling surgery using the urogenital distress inventory (UDI) and the short form of the incontinence impact questionnaire (...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.20318

    authors: Pianezza ML,Joffe R,Chugh T,Radomski SB

    更新日期:2007-01-01 00:00:00

  • Treatment of daytime urinary incontinence: A standardization document from the International Children's Continence Society.

    abstract:PURPOSE:This article is a standardization document of the International Children's Continence Society (ICCS); it represent a consensus of ICCS on the management of pediatric daytime urine incontinence (DUI). MATERIALS AND METHODS:This document was designed and written by a multi-disciplinary core group of authors appo...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,评审

    doi:10.1002/nau.22911

    authors: Chang SJ,Van Laecke E,Bauer SB,von Gontard A,Bagli D,Bower WF,Renson C,Kawauchi A,Yang SS

    更新日期:2017-01-01 00:00:00

  • Spontaneous voiding is surprisingly recoverable via outlet procedure in men with underactive bladder and documented detrusor underactivity on urodynamics.

    abstract:AIMS:To identify clinical and urodynamic factors leading to spontaneous voiding in men with detrusor underactivity (DU) and suspected bladder outlet obstruction who underwent an outlet de-obstruction procedure. METHODS:We identified 614 men who underwent an outlet procedure at our institution from 2005 to 2014. Men we...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章

    doi:10.1002/nau.24122

    authors: Dobberfuhl AD,Chen A,Alkaram AF,De EJB

    更新日期:2019-11-01 00:00:00

  • Game therapy a new approach to treat women facing mixed urinary incontinence: A study protocol.

    abstract:AIMS:To describe a pelvic floor muscle training (PFMT) isolated and associated with game therapy (PFMT + GT) for women facing mixed urinary incontinence (MUI) during climacteric period. METHODS:To standardize a randomized controlled clinical trial intervention, a protocol was created, in an attempt to decrease women's...

    journal_title:Neurourology and urodynamics

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/nau.24350

    authors: Oliveira MCE,Bezerra LO,Melo Ângelo PH,de Oliveira MC,Silva-Filho E,Ribeiro TS,Pegado R,Micussi MTABC

    更新日期:2020-06-01 00:00:00