Abstract:
AIMS:Prenatal myelomeningocele (MMC) repair has been proven to significantly reduce the need for hydrocephalus shunting and improve lower-extremity motor outcomes. The aim of this study was to evaluate the effect of prenatal MMC repair on the urological outcome. METHODS:All patients who underwent fetal MMC repair at our institution are followed prospectively. Assessments include medical history, renal and bladder ultrasound, voiding cystourethrogram and urodynamic study, need for clean intermittent catheterization (CIC) and anticholinergics, and the occurrence of urinary tract infections (UTI). RESULTS:Of the 30 patients who underwent prenatal MMC closure from December 2010 to December 2015, eight patients with a postnatal follow-up of at least 2 years were included in this study and compared with eight patients after postnatal MMC repair. The level of the bony spinal defect was similar in both groups. Urological evaluation at 2 years revealed normal bladder function in 50% after prenatal repair. Neurogenic bladder dysfunction requiring CIC and anticholinergic therapy was seen in 50% in the prenatal and in 100% in the postnatal group. Significant bladder wall thickening was found in 37.5% and 87.5%, respectively. Febrile UTIs occurred in 37.5% in the prenatal and 62.5% in the postnatal group during the observation period. CONCLUSIONS:Our data suggest a positive effect of prenatal MMC closure on lower urinary tract function. The long-term significance of these results remains unclear. Therefore, continued close monitoring of renal and bladder function are mandatory.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Horst M,Mazzone L,Schraner T,Bodmer C,Möhrlen U,Meuli M,Gobet Rdoi
10.1002/nau.23174subject
Has Abstractpub_date
2017-08-01 00:00:00pages
1651-1658issue
6eissn
0733-2467issn
1520-6777journal_volume
36pub_type
杂志文章abstract:AIMS:To determine the optimal stochastic whole body vibration (SR-WBV) load modality regarding pelvic floor muscle (PFM) activity in order to complete the SR-WBV training methodology for future PFM training with SR-WBV. METHODS:The continuous and the intermittent SR-WBV modalities were tested by means of electromyogra...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.21251
更新日期:2012-06-01 00:00:00
abstract:AIMS:To evaluate the feasibility and reliability of current perception threshold (CPT) measurement for sensory assessment of distinct locations in the male lower urinary tract (LUT). METHODS:Twelve male subjects (>18 years) without LUT symptoms or medical comorbidities were eligible. CPTs were determined twice (interv...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22956
更新日期:2017-02-01 00:00:00
abstract:AIM:To determine the optimal degree of pubovaginal slings (PVS) tension, measured by lax sling dimensions to minimize the risk of urinary retention. METHODS:This prospective study analyzed female patients undergoing PVS for stress urinary incontinence (SUI) by two surgeons over 24 months from January 2016. Intra-opera...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24000
更新日期:2019-06-01 00:00:00
abstract:AIM:We present the surgical management and outcomes of patients who underwent transvaginal neo-bladder vaginal fistula (NBVF) repair at our institution. METHODS:Between 2002 and 2012, eight patients underwent transvaginal NBVF repair. The surgical management entailed placing a Foley catheter into the fistula tract. A ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22687
更新日期:2016-01-01 00:00:00
abstract:AIM OF THE STUDY:To estimate the prevalence and 5-year incidence of lower urinary tract symptoms (LUTS) after the first delivery and to evaluate the impact of pregnancy per se and delivery per se on long-lasting symptoms. MATERIALS AND METHODS:A longitudinal cohort study of 305 primiparae questioned a few days, 3 mont...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.2198
更新日期:2002-01-01 00:00:00
abstract:AIMS:To report the state of the science on primary prevention of urinary incontinence (UI) in adults from the 6th International Consultation on Incontinence with an update through January 2019. METHODS:Online databases PubMed, CINAHL, PsycInfo, and Medline were searched in March 2016 and February 2019 with a focus on ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.24222
更新日期:2020-01-01 00:00:00
abstract:AIMS:Once-daily extended-release (XR) trospium chloride has been evaluated for the treatment of overactive bladder syndrome (OAB) in two 12-week randomized, double-blind, placebo-controlled studies. This pooled analysis of the 9-month open-label extensions to these studies evaluated the long-term efficacy and tolerabil...
journal_title:Neurourology and urodynamics
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doi:10.1002/nau.21000
更新日期:2011-09-01 00:00:00
abstract:AIMS:Urodynamic studies (UDS) are complex, invasive and may be emotionally and physically distressing. Inadequate information may heighten distress. Prior to UDS, our patients receive written and verbal information, yet concerns remains that some women may not be adequately informed. This study examined how informed wo...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21014
更新日期:2011-04-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23722
更新日期:2018-11-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,meta分析
doi:10.1002/nau.20243
更新日期:2006-01-01 00:00:00
abstract:AIMS:Minimum important difference (MID) estimates the minimum degree of change in an instrument's score that correlates with subjective sense of improvement. The aim of this study was to estimate the MID for the Urogenital Distress Inventory (UDI), Incontinence Impact Questionnaire (IIQ) and Overactive Bladder Question...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2011-09-01 00:00:00
abstract:AIMS:To determine cohort urethral length, identify epidemiological factors influencing the parameter and to establish the percentage of cases with clinically relevant outsized urethras. METHODS:Prospective cohort study conducted in two tertiary clinical centers between 2013 and 2017. Nine hundred and twenty seven cons...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23509
更新日期:2018-06-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23187
更新日期:2017-09-01 00:00:00
abstract:AIMS:This article reviews current knowledge of the underpinning mechanisms of how the bladder senses fullness locally and also revisits clinical measurements of lower urinary tract sensation. The former represents cellular sensing during bladder filling whereas the latter describes the sensations leading to conscious p...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.24273
更新日期:2020-07-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21193
更新日期:2012-04-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20375
更新日期:2007-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20654
更新日期:2009-01-01 00:00:00
abstract:AIM:Bladder outflow in women (bladder outlet obstruction [BOO]) has no well-accepted defining diagnostic criteria. Various nomograms exist based on flow rates, pressure-flow data, and fluoroscopy. We have prospectively evaluated the Solomon-Greenwell bladder outflow obstruction nomogram (SG BOO nomogram) as a measureme...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24347
更新日期:2020-06-01 00:00:00
abstract:AIMS:Open surgery is the most commonly used methodological approach for generating a partial bladder outlet obstruction (pBOO) animal model. Surgical suturing closing a part of the urethral meatus induces comparable pathophysiological changes in bladder and renal functions, but the optimum degree of obstruction that cl...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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更新日期:2018-09-01 00:00:00
abstract::For both treatment and research it is useful to classify detrusor hyperreflexia/instability according to degree of severity, because it relates to symptomatic impact. However, there has been no systematic evaluation of criteria for severity assignment. This report compares patient classification by urodynamic data acc...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930130507
更新日期:1994-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21152
更新日期:2011-11-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10173
更新日期:2004-01-01 00:00:00
abstract:AIM:To conduct an evidence synthesis of normative reference values for bladder function parameters in women. METHODS:We conducted a systematic review and meta-analysis of studies reporting bladder function parameters obtained from noninvasive tests in healthy women. Seven databases were searched for relevant studies f...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,meta分析
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更新日期:2020-02-01 00:00:00
abstract:AIMS:Due to a paucity of evidence-based guidelines, anecdotal practice patterns often dictate clinical management of recurrent urinary tract infection (UTI) in women. Our aim was to identify pathologic findings of the urinary tract through cystoscopy and imaging in women with recurrent UTI, and to determine if specific...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22998
更新日期:2017-03-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
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更新日期:2008-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章
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更新日期:2007-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930140206
更新日期:1995-01-01 00:00:00
abstract::This study investigated the effects of outlet obstruction on blood flow and high energy phosphates content in the rabbit urinary bladder. Mild bladder outlet obstruction was induced by placing a silicon ring (diameter 7 mm) around the bladder neck of each male New Zealand White rabbit (n = 7). Before and immediately a...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930140309
更新日期:1995-01-01 00:00:00