Blockade of estrogen receptors decreases CNS and pituitary prostaglandin synthase expression in fetal sheep.

abstract：:Somatostatin (ST) inhibits gastrointestinal motility and exocrine and endocrine secretions. In animals, ST has been demonstrated to decrease food intake. We investigated, in a randomized double-blind investigation in 10 healthy humans, the effects of an intravenous ST infusion compared to saline on subjective hunger f...

journal_title：Neuroendocrinology

authors： Lieverse RJ,Jansen JB,Masclee AM,Lamers CB

更新日期：1995-02-01 00:00:00

abstract：:The properties of neuronal-type nicotinic acetylcholine receptors (nAChRs) present on the neuroendocrine cells of the porcine pars intermedia of the pituitary were studied in intact single cell using measurements of the free intracellular Ca2+ concentration ([Ca]i) with the calcium-sensitive dye fura 2. Local applicat...

journal_title：Neuroendocrinology

authors： Poisbeau P,Trouslard J,Feltz P,Schlichter R

更新日期：1994-10-01 00:00:00

abstract：INTRODUCTION:Pituitary neuroendocrine tumors (PitNETs), the most abundant of all intracranial tumors, entail severe comorbidities. First-line therapy is transsphenoidal surgery, but subsequent pharmacological therapy is often required. Unfortunately, many patients are/become unresponsive to available drugs (somatostati...

journal_title：Neuroendocrinology

authors： Vázquez-Borrego MC,Fuentes-Fayos AC,Herrera-Martínez AD,Venegas-Moreno E,L-López F,Fanciulli A,Moreno-Moreno P,Alhambra-Expósito MR,Barrera-Martín A,Dios E,Blanco-Acevedo C,Solivera J,Granata R,Kineman RD,Gahete MD,Soto-Mor

更新日期：2020-01-01 00:00:00

abstract：:We have suggested that gamma-aminobutyric acid (GABA) in the hypothalamus plays a tonic inhibitory role in the control of the luteinizing hormone (LH) release in intact male rats. To assess whether feedback from the testis alters the inhibitory GABAergic tone in the medial preoptic area (MPO) of male rats, an in vivo ...

journal_title：Neuroendocrinology

authors： Tin-Tin-Win-Shwe,Mitsushima D,Kimura F

更新日期：2002-11-01 00:00:00

abstract：:Structural and functional impairment of the skeletal system remains an important cause of morbidity and disability in patients with Cushing's syndrome (CS). Glucocorticoid (GC) excess inhibits bone formation and calcium absorption from the gut, increases bone resorption, and alters the secretion of gonadotropin and gr...

journal_title：Neuroendocrinology

authors： Kaltsas G,Makras P

更新日期：2010-01-01 00:00:00

abstract：:In previous studies, we have shown that male Wistar rats exposed to a single inescapable stressor session (15 min restraint) exhibited 24 h later an anxiogenic-like behavior in the elevated plus-maze (EPM), which was reversed by inhibition of corticosterone (CS) synthesis with metyrapone (75 mg/kg i.p.) 3 h before str...

journal_title：Neuroendocrinology

authors： Calvo N,Volosin M

更新日期：2001-04-01 00:00:00

abstract：:Medial parvocellular paraventricular corticotropin-releasing hormone (mPVN CRH) cells are critical in generating hypothalamic-pituitary-adrenal (HPA) axis responses to systemic interleukin-1beta (IL-1beta). However, although it is understood that catecholamine inputs are important in initiating mPVN CRH cell responses...

journal_title：Neuroendocrinology

authors： Buller K,Xu Y,Dayas C,Day T

更新日期：2001-02-01 00:00:00

abstract：:Previous studies indicate that 7 days after testicular administration of naloxone, serum testosterone (T) concentration and basal T secretion in vitro decrease significantly. In neonatal rats, short-term (2 h) intratesticular treatment with 0.3 micrograms (D-Met2-Pro5)-enkephalinamide suppresses steroidogenesis. In th...

journal_title：Neuroendocrinology

authors： Gerendai I,Nemeskéri A,Csernus V

更新日期：1992-09-01 00:00:00

abstract：:We measured the concentration of oxytocin and vasopressin in microdissected areas of the hypothalamus and posterior pituitary in weanling and adult female rats. Oxytocin concentration was significantly less in adult rats as compared to weanling rats in the supraoptic nucleus, median eminence, and retrochiasmatic area ...

journal_title：Neuroendocrinology

authors： Jackson R,George JM

更新日期：1980-08-01 00:00:00

abstract：:Delta-sleep-inducing peptide (DSIP) colocalizes within gonadotropin-releasing-hormone (GnRH)-containing neurons in adult hypothalamus and could play a role in the regulation of hypothalamic-pituitary axis in adults. To support the possibility that DSIP also participates in fetal neuroendocrine events and to demonstrat...

journal_title：Neuroendocrinology

authors： Pu LP,Dubois PM

更新日期：1992-01-01 00:00:00

abstract：:To assess whether gonadotropin-releasing hormone (GnRH) release from the hypothalamus might be altered by hyperprolactinemia in the male rat, we measured in chronically hyperprolactinemic rats the pituitary GnRH receptor content and described the pattern of luteinizing hormone (LH) release during the postcastration ri...

journal_title：Neuroendocrinology

authors： Fox SR,Hoefer MT,Bartke A,Smith MS

更新日期：1987-10-01 00:00:00

abstract：:Anterior pituitaries from female Sprague-Dawley rats (160-200 g b.w) bearing electrolytic lesions of the median eminence were qualitatively and quantitatively investigated by electron microscopy and the findings compared with those from intact animals or sham-operated controls. This study was performed in basal condit...

journal_title：Neuroendocrinology

authors： Rossi GL,Probst D,Panerai AE,Cocchi D,Locatelli V,Müller EE

更新日期：1979-01-01 00:00:00

abstract：:The secretion of gonadotropins and the role exerted by the endogenous opioid system on luteinizing hormone (LH) secretion were investigated in 6 postmenopausal women affected by idiopathic Parkinson's disease (PD) as well as in 6 age- and weight-matched normal postmenopausal women as controls. The mean plasma follicle...

journal_title：Neuroendocrinology

authors： Cagnacci A,Melis GB,Soldani R,Bonuccelli U,Piccini P,Napolitano A,Muratorio A,Fioretti P

更新日期：1991-06-01 00:00:00

abstract：:Hereditary cases of growth hormone (GH)-secreting tumors have been classified into three clinical entities: the multiple endocrine neoplasia type 1 (MEN1) syndrome, the Carney complex (CNC) and the isolated familial somatotropinomas (IFS). The genomic defects associated with MEN1 are all linked to various mutations of...

journal_title：Neuroendocrinology

authors： Lytras A,Tolis G

更新日期：2006-01-01 00:00:00

abstract：:Dehydration is a classic homeostatic stressor in rats that leads to a series of endocrine responses including stimulation of the hypothalamo-pituitary-adrenal (HPA) axis. During the last decade, it has been well established that perinatal food restriction is associated with the onset of diseases in adults. Our previou...

journal_title：Neuroendocrinology

authors： Sebaai N,Lesage J,Breton C,Vieau D,Deloof S

更新日期：2004-01-01 00:00:00

abstract：:Hypophysitis is a relatively rare disease that exerts a strong autoimmune component encompassing different etiologies. Immunomodulatory drugs, such as interferon-α, are known to rarely induce hypophysitis. In recent years, a large number of new biological and immunomodulatory agents have been introduced into clinical ...

journal_title：Neuroendocrinology

authors： Angelousi A,Chatzellis E,Kaltsas G

更新日期：2018-01-01 00:00:00

abstract：:Tissue-specific stem cells are uncovered in a growing number of organs by their molecular expression profile and their potential for self-renewal, multipotent differentiation and tissue regeneration. Whether the pituitary gland also contains a pool of versatile 'master' cells that drive homeostatic, plastic and regene...

journal_title：Neuroendocrinology

authors： Vankelecom H

更新日期：2007-01-01 00:00:00

abstract：:Primary cultures from fetal rat brain contain angiotensin II immunoreactivity in neurons. To study the origin of this immunoreactivity, primary cultures were incubated with [3H]-valine or [3H]-isoleucine. A time-dependent incorporation of radioactivity into immunoprecipitable angiotensin II was observed. Incubation of...

journal_title：Neuroendocrinology

authors： Raizada MK,Phillips MI,Gerndt JS

更新日期：1983-01-01 00:00:00

abstract：:Glass microknife lesions and immunocytochemistry were used to evaluate luteinizing hormone-releasing hormone (LH-RH)- and somatostatin (SS)-immunoreactive pathways from the preoptic region to the rat median eminence. Cuts were so placed that axons of more caudally located neurons in the periventricular hypothalamic ar...

journal_title：Neuroendocrinology

authors： Jew JY,Léránth C,Arimura A,Palkovits M

更新日期：1984-03-01 00:00:00

abstract：:Introduction Autophagic cell death in cancer cells can be mediated by inhibition of deacetylases. Although extensive studies have focused on the autophagic process in cancer, little is known about the role of autophagy in degrading cytosolic and nuclear components of pancreatic neuroendocrine neoplastic (pNEN) cells l...

journal_title：Neuroendocrinology

authors： Matrood S,de Prisco N,Wissniowski T,Wiese D,Jabari S,Griesmann H,Wanzel M,Stiewe T,Neureiter D,Klieser E,Mintziras I,Buchholz M,Bartsch DK,Gennarino V,Di Fazio P

更新日期：2020-10-27 00:00:00

abstract：:Vasopressin and oxytocin modulate memory processes which effects are dissociated from the typical peripheral endocrine effects of these neuropeptides. Recently, vasopressin has been implicated in the regulation of body temperature. In view of this, experiments were designed to determine whether the antipyretic effect ...

journal_title：Neuroendocrinology

authors： Kovács GL,De Wied D

更新日期：1983-10-01 00:00:00

abstract：:17 alpha-hydroxyprogesterone (up to 200 mug/day) and 11 beta-hydroxyandrostenedione (up to 500 mug) had no effect on PMS-induced ovulation in intact immature rats. 10 mug/day of testosterone propoinate (TP) on days 28-30 of life decreased the percent of animals ovulating and the number of ova produced; this effect per...

journal_title：Neuroendocrinology

authors： Hagino N,Goldzieher JW

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND/AIMS:Plasma chromogranin A (CgA) is the most widely used biochemical biomarker in the diagnostic workup and follow-up of gastroenteropancreatic neuroendo- crine neoplasms (GEP-NENs). Herein, we assessed the clinical utility of CgA in diagnosing and monitoring a large series of GEP-NENs. PATIENTS AND METHODS...

journal_title：Neuroendocrinology

authors： Massironi S,Rossi RE,Casazza G,Conte D,Ciafardini C,Galeazzi M,Peracchi M

更新日期：2014-01-01 00:00:00

abstract：:The expression of the mouse metallothionein-I (mMT) promoter/human growth hormone (hGH) fusion gene in transgenic mice leads to female sterility and major alterations in the function of the hypothalamic-adenohypophyseal system. These alterations include increases in median-eminence norepinephrine turnover and plasma L...

journal_title：Neuroendocrinology

authors： Steger RW,Bartke A,Parkening TA,Collins T,Buonomo FC,Tang KC,Wagner TE,Yun JS

更新日期：1991-04-01 00:00:00

abstract：:Studies were performed to determine the role of thyroid hormone in the suppression of thyrotropin (TSH) by opiates. Serum samples were collected by decapitation 1, 3, 6, 12, 24, or 48 h after rats were implanted with 1 sustained-release morphine (75 mg) or placebo pellet. Morphine decreased TSH by 44% at 1 h and by 83...

journal_title：Neuroendocrinology

authors： Berglund LA,Millard WJ,Gabriel SM,Simpkins JW

更新日期：1990-09-01 00:00:00

abstract：:The hypothesis was tested that corticotropin-releasing factor (CRF) is involved in the inhibition of gonadotropin secretion during chronic hyperprolactinemia. Two models of hyperprolactinemia were used, namely inoculation with the prolactin (PRL)-secreting tumor 7315b and implantation of isogenic pituitary glands. Gon...

journal_title：Neuroendocrinology

authors： Kooy A,de Greef WJ,Vreeburg JT,Hackeng WH,Ooms MP,Lamberts SW,Weber RF

更新日期：1990-03-01 00:00:00

abstract：:Chronic administration of the mineralocorticoid deoxycorticosterone acetate (DOCA) induces a steady and robust increase in salt appetite and plasma Na(+) over the course of treatment. Interestingly, salt appetite behavior persists in rats even with elevated plasma Na(+) levels. Since there is evidence that the pathway...

journal_title：Neuroendocrinology

authors： Lucas LR,Pompei P,McEwen BS

更新日期：2000-06-01 00:00:00

abstract：:Three control point enzymes of the Embden-Meyerhof pathway, hexokinase (HK), phosphofructokinase (PFK) and pyruvate kinase (PK) were measured by quantitative histochemical methods in individual hypothalamic nuclei of adult neonatally androgenized female rats. HK activity was significantly increased in anterior hypotha...

journal_title：Neuroendocrinology

authors： Packman PM,Bragdon MJ,Boshans RL

更新日期：1977-01-01 00:00:00

abstract：:In the Siberian hamster the pituitary content of bioassayable MSH has been shown to be seasonally variable, being greater during the long days of spring and summer than during the short days of autumn and winter. Similar changes in the pituitary content of both bioassayable MSH and immunoreactive alpha MSH can be indu...

journal_title：Neuroendocrinology

authors： Logan A,Weatherhead B

更新日期：1980-05-01 00:00:00

abstract：:Knowledge of specific neurotransmitters as well as the pathways and mechanisms regulating appetite in ruminants that continually graze, such as sheep, is incomplete. Although fundamentally agouti-related protein (AGRP) has a similar function across species to increase food intake, the regulation of AGRP may vary acros...

journal_title：Neuroendocrinology

authors： Wagner CG,McMahon CD,Marks DL,Daniel JA,Steele B,Sartin JL

更新日期：2004-01-01 00:00:00