"Before we used to get sick all the time": perceptions of malaria and use of long-lasting insecticide-treated bed nets (LLINs) in a rural Kenyan community.


BACKGROUND:Malaria is a leading global cause of preventable morbidity and mortality, especially in sub-Saharan Africa, despite recent advances in treatment and prevention technologies. Scale-up and wide distribution of long-lasting insecticide-treated nets (LLINs) could rapidly decrease malarial disease in endemic areas, if used properly and continuously. Studies have shown that effective use of LLINs depends, in part, upon understanding causal factors associated with malaria. This study examined malaria beliefs, attitudes, and practices toward LLINs assessed during a large-scale integrated prevention campaign (IPC) in rural Kenya. METHODS:Qualitative interviews were conducted with 34 IPC participants who received LLINs as part of a comprehensive prevention package of goods and services. One month after distribution, interviewers asked these individuals about their attitudes and beliefs regarding malaria, and about their use of LLINs. RESULTS:Virtually all participants noted that mosquitoes were involved in causing malaria, though a substantial proportion of participants (47 percent) also mentioned an incorrect cause in addition to mosquitoes. For example, participants commonly noted that the weather (rain, cold) or consumption of bad food and water caused malaria. Regardless, most participants used the LLINs they were given and most mentioned positive benefits from their use, namely reductions in malarial illness and in the costs associated with its diagnosis and treatment. CONCLUSIONS:Attitudes toward LLINs were positive in this rural community in Western Kenya, and respondents noted benefits with LLIN use. With improved understanding and clarification of the direct (mosquitoes) and indirect (e.g., standing water) causes of malaria, it is likely that LLIN use can be sustained, offering effective household-level protection against malaria.


Malar J


Malaria journal


Dye TD,Apondi R,Lugada ES,Kahn JG,Smith J,Othoro C




Has Abstract


2010-11-30 00:00:00










  • System effectiveness of a targeted free mass distribution of long lasting insecticidal nets in Zanzibar, Tanzania.

    abstract:BACKGROUND:Insecticide-treated nets (ITN) and long-lasting insecticidal treated nets (LLIN) are important means of malaria prevention. Although there is consensus regarding their importance, there is uncertainty as to which delivery strategies are optimal for dispensing these life saving interventions. A targeted mass ...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Beer N,Ali AS,de Savigny D,Al-Mafazy AW,Ramsan M,Abass AK,Omari RS,Björkman A,Källander K

    更新日期:2010-06-18 00:00:00

  • Longitudinal study on Plasmodium falciparum gametocyte carriage following artemether-lumefantrine administration in a cohort of children aged 12-47 months living in Western Kenya, a high transmission area.

    abstract:BACKGROUND:The effects that artemether-lumefantrine (AL) has on gametocyte dynamics in the short-term have recently been described. However there is limited long-term longitudinal data on the effect of AL on gametocyte dynamics in asymptomatic children. METHODS:An epidemiological study was conducted in Kombewa, Wester...

    journal_title:Malaria journal

    pub_type: 杂志文章,随机对照试验


    authors: Andagalu B,Mativo J,Kamau E,Ogutu B

    更新日期:2014-07-09 00:00:00

  • G6PD deficiency alleles in a malaria-endemic region in the Western Brazilian Amazon.

    abstract:BACKGROUND:Plasmodium vivax parasites are the predominant cause of malaria infections in the Brazilian Amazon. Infected individuals are treated with primaquine, which can induce haemolytic anaemia in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals and may lead to severe and fatal complications. This X-li...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Dombrowski JG,Souza RM,Curry J,Hinton L,Silva NRM,Grignard L,Gonçalves LA,Gomes AR,Epiphanio S,Drakeley C,Huggett J,Clark TG,Campino S,Marinho CRF

    更新日期:2017-06-15 00:00:00

  • Effect of climatic variability on malaria trends in Baringo County, Kenya.

    abstract:BACKGROUND:Malaria transmission in arid and semi-arid regions of Kenya such as Baringo County, is seasonal and often influenced by climatic factors. Unravelling the relationship between climate variables and malaria transmission dynamics is therefore instrumental in developing effective malaria control strategies. The ...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Kipruto EK,Ochieng AO,Anyona DN,Mbalanya M,Mutua EN,Onguru D,Nyamongo IK,Estambale BBA

    更新日期:2017-05-25 00:00:00

  • Spatial prediction of malaria prevalence in an endemic area of Bangladesh.

    abstract:BACKGROUND:Malaria is a major public health burden in Southeastern Bangladesh, particularly in the Chittagong Hill Tracts region. Malaria is endemic in 13 districts of Bangladesh and the highest prevalence occurs in Khagrachari (15.47%). METHODS:A risk map was developed and geographic risk factors identified using a B...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Haque U,Magalhães RJ,Reid HL,Clements AC,Ahmed SM,Islam A,Yamamoto T,Haque R,Glass GE

    更新日期:2010-05-09 00:00:00

  • Patterns of inflammatory responses and parasite tolerance vary with malaria transmission intensity.

    abstract:BACKGROUND:In individuals living in malaria-endemic regions, parasitaemia thresholds for the onset of clinical symptoms vary with transmission intensity. The mechanisms that mediate this relationship are however, unclear. Since inflammatory responses to parasite infection contribute to the clinical manifestation of mal...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Ademolue TW,Aniweh Y,Kusi KA,Awandare GA

    更新日期:2017-04-11 00:00:00

  • The dimerization domain of PfCENP-C is required for its functions as a centromere protein in human malaria parasite Plasmodium falciparum.

    abstract:BACKGROUND:The conserved centromere-associated proteins, CENH3 (or CENP-A) and CENP-C are indispensable for the functional centromere-kinetochore assembly, chromosome segregation, cell cycle progression, and viability. The presence and functions of centromere proteins in Plasmodium falciparum are not well studied. Iden...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Verma G,Surolia N

    更新日期:2014-12-04 00:00:00

  • Therapeutic efficacy of artemether-lumefantrine in uncomplicated falciparum malaria in India.

    abstract:BACKGROUND:Artemisinin-based combination therapy (ACT) is the treatment of choice for uncomplicated falciparum malaria. Artemether-lumefantrine (AL), a fixed dose co-formulation, has recently been approved for marketing in India, although it is not included in the National Drug Policy for treatment of malaria. Efficacy...

    journal_title:Malaria journal

    pub_type: 临床试验,杂志文章


    authors: Valecha N,Srivastava P,Mohanty SS,Mittra P,Sharma SK,Tyagi PK,Pradhan K,Dev V,Singh R,Dash AP,Sharma YD

    更新日期:2009-05-19 00:00:00

  • Screening for adulticidal bioactivity of South African plants against Anopheles arabiensis.

    abstract:BACKGROUND:This study was conducted to evaluate whether a selection of South African ethnomedicinal plants included in this study displayed insecticidal properties when screened against adult stages of the mosquito. METHODS:381 crude extracts of 80 plant taxa in 42 families were sprayed onto ceramic tiles and screened...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Maharaj R,Maharaj V,Crouch NR,Bhagwandin N,Folb PI,Pillay P,Gayaram R

    更新日期:2011-08-11 00:00:00

  • Malaria risk and access to prevention and treatment in the paddies of the Kilombero Valley, Tanzania.

    abstract:BACKGROUND:The Kilombero Valley is a highly malaria-endemic agricultural area in south-eastern Tanzania. Seasonal flooding of the valley is favourable to malaria transmission. During the farming season, many households move to distant field sites (shamba in Swahili) in the fertile river floodplain for the cultivation o...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Hetzel MW,Alba S,Fankhauser M,Mayumana I,Lengeler C,Obrist B,Nathan R,Makemba AM,Mshana C,Schulze A,Mshinda H

    更新日期:2008-01-09 00:00:00

  • Micro-heterogeneity of malaria transmission in the Peruvian Amazon: a baseline assessment underlying a population-based cohort study.

    abstract:BACKGROUND:Understanding the dynamics of malaria transmission in diverse endemic settings is key for designing and implementing locally adapted and sustainable control and elimination strategies. A parasitological and epidemiological survey was conducted in September-October 2012, as a baseline underlying a 3-year popu...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Rosas-Aguirre A,Guzman-Guzman M,Gamboa D,Chuquiyauri R,Ramirez R,Manrique P,Carrasco-Escobar G,Puemape C,Llanos-Cuentas A,Vinetz JM

    更新日期:2017-08-04 00:00:00

  • Shifting transmission risk for malaria in Africa with climate change: a framework for planning and intervention.

    abstract:BACKGROUND:Malaria continues to be a disease of massive burden in Africa, and the public health resources targeted at surveillance, prevention, control, and intervention comprise large outlays of expense. Malaria transmission is largely constrained by the suitability of the climate for Anopheles mosquitoes and Plasmodi...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Ryan SJ,Lippi CA,Zermoglio F

    更新日期:2020-05-01 00:00:00

  • Towards a re-emergence of chloroquine sensitivity in Côte d'Ivoire?

    abstract:BACKGROUND:Resistance of Plasmodium falciparum to anti-malarial drugs has hampered efforts to eradicate malaria. Recent reports of a decline in the prevalence of chloroquine-resistant P. falciparum in several countries, including Malawi and Zambia, is raising the hope of reintroducing chloroquine in the near future, id...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Dagnogo O,Ako AB,Ouattara L,Dago ND,Coulibaly DN,Touré AO,Djaman JA

    更新日期:2018-11-07 00:00:00

  • Characterizing microclimate in urban malaria transmission settings: a case study from Chennai, India.

    abstract:BACKGROUND:Environmental temperature is an important driver of malaria transmission dynamics. Both the parasite and vector are sensitive to mean ambient temperatures and daily temperature variation. To understand transmission ecology, therefore, it is important to determine the range of microclimatic temperatures exper...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Cator LJ,Thomas S,Paaijmans KP,Ravishankaran S,Justin JA,Mathai MT,Read AF,Thomas MB,Eapen A

    更新日期:2013-03-02 00:00:00

  • Associations between red blood cell variants and malaria among children and adults from three areas of Uganda: a prospective cohort study.

    abstract:BACKGROUND:Multiple red blood cell (RBC) variants appear to offer protection against the most severe forms of Plasmodium falciparum malaria. Associations between these variants and uncomplicated malaria are less clear. METHODS:Data from a longitudinal cohort study conducted in 3 sub-counties in Uganda was used to quan...

    journal_title:Malaria journal

    pub_type: 杂志文章,多中心研究


    authors: Kakande E,Greenhouse B,Bajunirwe F,Drakeley C,Nankabirwa JI,Walakira A,Nsobya SL,Katureebe A,Rek J,Arinaitwe E,Rosenthal PJ,Kamya MR,Dorsey G,Rodriguez-Barraquer I

    更新日期:2020-01-15 00:00:00

  • Avian Plasmodium in Eastern Austrian mosquitoes.

    abstract:BACKGROUND:Insect vectors, namely mosquitoes (Diptera: Culicidae), are compulsory for malaria parasites (Plasmodium spp.) to complete their life cycle. Despite this, little is known about vector competence of different mosquito species for the transmission of avian malaria parasites. METHODS:In this study, nested PCR ...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Schoener E,Uebleis SS,Butter J,Nawratil M,Cuk C,Flechl E,Kothmayer M,Obwaller AG,Zechmeister T,Rubel F,Lebl K,Zittra C,Fuehrer HP

    更新日期:2017-09-29 00:00:00

  • Successful malaria elimination in the Ecuador-Peru border region: epidemiology and lessons learned.

    abstract:BACKGROUND:In recent years, malaria (Plasmodium vivax and Plasmodium falciparum) has been successfully controlled in the Ecuador-Peru coastal border region. The aim of this study was to document this control effort and to identify the best practices and lessons learned that are applicable to malaria control and to othe...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Krisher LK,Krisher J,Ambuludi M,Arichabala A,Beltrán-Ayala E,Navarrete P,Ordoñez T,Polhemus ME,Quintana F,Rochford R,Silva M,Bazo J,Stewart-Ibarra AM

    更新日期:2016-11-28 00:00:00

  • Fast track antibody V-gene rescue, recombinant expression in plants and characterization of a PfMSP4-specific antibody.

    abstract:BACKGROUND:Monoclonal antibodies (mAbs) are essential tools in biological research, diagnosis and therapy, and are conventionally produced in murine hybridoma cell lines. Professional applications of mAbs depend on the steady supply of material. Because hybridoma cultures can stop producing the antibody or even die, pr...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Kapelski S,Boes A,Spiegel H,de Almeida M,Klockenbring T,Reimann A,Fischer R,Barth S,Fendel R

    更新日期:2015-02-05 00:00:00

  • In vitro selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemisinin.

    abstract:BACKGROUND:Anti-malarial drugs are the major focus in the prevention and treatment of malaria. Artemisinin-based combination therapy (ACT) is the WHO recommended first-line treatment for Plasmodium falciparum malaria across the endemic world. Also ACT is increasingly relied upon in treating Plasmodium vivax malaria whe...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Njokah MJ,Kang'ethe JN,Kinyua J,Kariuki D,Kimani FT

    更新日期:2016-07-22 00:00:00

  • Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort.

    abstract:BACKGROUND:There is limited data available regarding safety profile of artemisinins in early pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for malaria in first trimester due to associated embryo-foetal toxicity in animal studies. The study assessed birth outcome among pregnant women i...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Mosha D,Mazuguni F,Mrema S,Sevene E,Abdulla S,Genton B

    更新日期:2014-05-27 00:00:00

  • Model variations in predicting incidence of Plasmodium falciparum malaria using 1998-2007 morbidity and meteorological data from south Ethiopia.

    abstract:BACKGROUND:Malaria transmission is complex and is believed to be associated with local climate changes. However, simple attempts to extrapolate malaria incidence rates from averaged regional meteorological conditions have proven unsuccessful. Therefore, the objective of this study was to determine if variations in spec...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Loha E,Lindtjørn B

    更新日期:2010-06-16 00:00:00

  • Primaquine ineligibility in anti-relapse therapy of Plasmodium vivax malaria: the problem of G6PD deficiency and cytochrome P-450 2D6 polymorphisms.

    abstract::The hypnozoite reservoir of Plasmodium vivax represents both the greatest obstacle and opportunity for ultimately eradicating this species. It is silent and cannot be diagnosed until it awakens and provokes a clinical attack with attendant morbidity, risk of mortality, and opportunities for onward transmission. The on...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Baird JK,Battle KE,Howes RE

    更新日期:2018-01-22 00:00:00

  • High-resolution metabolomics to discover potential parasite-specific biomarkers in a Plasmodium falciparum erythrocytic stage culture system.

    abstract:BACKGROUND:Current available malaria diagnostic methods each have some limitations to meet the need for real-time and large-scale screening of asymptomatic and low density malaria infection at community level. It was proposed that malaria parasite-specific low molecular-weight metabolites could be used as biomarkers fo...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Park YH,Shi YP,Liang B,Medriano CA,Jeon YH,Torres E,Uppal K,Slutsker L,Jones DP

    更新日期:2015-03-24 00:00:00

  • Infectious reservoir of Plasmodium infection in Mae Hong Son Province, north-west Thailand.

    abstract:BACKGROUND:It was unknown whether the main reservoir of Plasmodium falciparum and Plasmodium vivax, which infects mosquitoes in Thailand, was (a) in people feeling sufficiently ill with malaria to come to a clinic or (b) in people who had remained in their home villages with some fever symptoms or with none. METHODS:M...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Pethleart A,Prajakwong S,Suwonkerd W,Corthong B,Webber R,Curtis C

    更新日期:2004-09-22 00:00:00

  • Geo-additive modelling of malaria in Burundi.

    abstract:BACKGROUND:Malaria is a major public health issue in Burundi in terms of both morbidity and mortality, with around 2.5 million clinical cases and more than 15,000 deaths each year. It is still the single main cause of mortality in pregnant women and children below five years of age. Because of the severe health and eco...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Nkurunziza H,Gebhardt A,Pilz J

    更新日期:2011-08-11 00:00:00

  • Malaria diagnostic testing and treatment practices in three different Plasmodium falciparum transmission settings in Tanzania: before and after a government policy change.

    abstract:BACKGROUND:Patterns of decreasing malaria transmission intensity make presumptive treatment of malaria an unjustifiable approach in many African settings. The controlled use of anti-malarials after laboratory confirmed diagnosis is preferable in low endemic areas. Diagnosis may be facilitated by malaria rapid diagnosti...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Bastiaens GJ,Schaftenaar E,Ndaro A,Keuter M,Bousema T,Shekalaghe SA

    更新日期:2011-04-02 00:00:00

  • The response of Plasmodium falciparum to isoleucine withdrawal is dependent on the stage of progression through the intraerythrocytic cell cycle.

    abstract:BACKGROUND:A previous study reported that the malaria parasite Plasmodium falciparum enters an altered growth state upon extracellular withdrawal of the essential amino acid isoleucine. Parasites slowed transit through the cell cycle when deprived of isoleucine prior to the onset of S-phase. METHODS:This project was u...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: McLean KJ,Jacobs-Lorena M

    更新日期:2020-04-08 00:00:00

  • The prognostic utility of bedside assessment of adults hospitalized with malaria in Myanmar: a retrospective analysis.

    abstract:BACKGROUND:Data collected in clinical trials have been used to develop scoring systems that identify adults with malaria at greatest risk of death. One of these, the RCAM score, can be simply determined by measuring a patient's Glasgow Coma Score and respiratory rate on admission to hospital. However the safety of usin...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Kaung M,Kyi TT,Aung NM,Kyaw MP,Min M,Htet ZW,Anstey NM,Kyi MM,Hanson J

    更新日期:2015-02-07 00:00:00

  • Mass drug administration of ivermectin in south-eastern Senegal reduces the survivorship of wild-caught, blood fed malaria vectors.

    abstract:BACKGROUND:In south-eastern Senegal, malaria and onchocerciasis are co-endemic. Onchocerciasis in this region has been controlled by once or twice yearly mass drug administration (MDA) with ivermectin (IVM) for over fifteen years. Since laboratory-raised Anopheles gambiae s.s. are susceptible to ivermectin at concentra...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Sylla M,Kobylinski KC,Gray M,Chapman PL,Sarr MD,Rasgon JL,Foy BD

    更新日期:2010-12-20 00:00:00

  • Longitudinal in vitro surveillance of Plasmodium falciparum sensitivity to common anti-malarials in Thailand between 1994 and 2010.

    abstract:BACKGROUND:Drug and multidrug-resistant Plasmodium falciparum malaria has existed in Thailand for several decades. Furthermore, Thailand serves as a sentinel for drug-resistant malaria within the Greater Mekong sub-region. However, the drug resistance situation is highly dynamic, changing quickly over time. Here parasi...

    journal_title:Malaria journal

    pub_type: 杂志文章


    authors: Parker D,Lerdprom R,Srisatjarak W,Yan G,Sattabongkot J,Wood J,Sirichaisinthop J,Cui L

    更新日期:2012-08-21 00:00:00