Abstract：
:An ultrastructural study of Bruch's membrane in 68 human eyes including at least five individuals from each of ten decades of life showed that changes began in the second decade in macular specimens but were delayed in nonmacular specimens. All specimens from 20-year-old donors had altered macular Bruch's membranes. The severity of changes increased with age. The most common change for all ages was debris on both sides of the elastic layer. Drusen sites often showed no debris in the underlying outer collagenous zone, suggesting that drusen may result from failure of dispersal of the accumulated material at these sites. Secretion by pigment epithelium of a "linear basal deposit" is a late (after the age of 50 years) change.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Feeney-Burns L,Ellersieck MRdoi
10.1016/0002-9394(85)90625-7subject
Has Abstractpub_date
1985-11-15 00:00:00pages
686-97issue
5eissn
0002-9394issn
1879-1891pii
0002-9394(85)90625-7journal_volume
100pub_type
杂志文章abstract：:Two patients underwent vitrectomy with the use of intraocular gas. In one patient the cornea decompensated because of lens-cornea contact and in the second patient a surgical technique devised to protect the cornea from lens contact was used successfully. The technique consisted of injecting a smaller gas bubble into ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(80)90284-6
更新日期：1980-05-01 00:00:00
abstract：:We determined antigens of the major histocompatibility complex classes I, II, and III in 25 families of Mexican mestizo glaucomatous patients. Patients and family members were examined, and the predisposition of first-degree relatives to a corticosteroid-provocative test was determined. The results showed a high frequ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72553-x
更新日期：1994-12-15 00:00:00
abstract：PURPOSE:To report a case of bilateral periopticoscleral hemorrhages associated with traumatic child abuse. METHODS:Postmortem gross examination and histopathologic studies of both eyes and the optic nerves of a 6-month-old infant who died from subdural hematoma. RESULTS:Gross examination and histopathologic step sect...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00392-4
更新日期：1999-04-01 00:00:00
abstract：PURPOSE:To compare the clinical features and antibiotic susceptibility of ocular methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA). DESIGN:Cross-sectional study. METHODS:The Proctor clinical laboratory database was reviewed to identify all ocular isolates of S. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.03.032
更新日期：2007-08-01 00:00:00
abstract：PURPOSE:To classify and describe clinically meaningful classes of color vision defects using pretreatment Farnsworth-Munsell 100-hue results from the Early Treatment Diabetic Retinopathy Study (ETDRS) patients using standard statistical techniques. DESIGN:The ETDRS was a randomized trial investigating retinal photocoa...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ajo.2004.02.009
更新日期：2004-07-01 00:00:00
abstract：PURPOSE:To determine the etiologies and management of calcific band keratopathy (CBK), and assess the results and long-term follow-up after ethylenediamine-tetraacetic acid (EDTA) chelation. DESIGN:Retrospective interventional case series. METHODS:Two hundred thirty patients with clinically significant CBK were inclu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.01.036
更新日期：2004-06-01 00:00:00
abstract：:Leber's hereditary optic neuropathy is caused by a single nucleotide change in the mitochondrial deoxyribonucleic acid (mtDNA). Each cell contains thousands of mitochondrial DNA molecules. We demonstrated that in certain isolated instances, the proband and close maternal lineage relatives can have mixtures of mutant a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72429-8
更新日期：1990-06-15 00:00:00
abstract：:Extraocular bacterial culture was performed in 100 patients with hypovitaminosis A xerophthalmia. There was corneal ulceration in 29 cases and corneal perforation in 22 cases. Eighty-six percent of the patients harbored frankly pathogenic bacteria (46 patients) and potentially pathogenic bacteria (40 patients). All bu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90399-2
更新日期：1975-10-01 00:00:00
abstract：PURPOSE:To review the contributions to ophthalmic genetics through the American Journal of Ophthalmology (AJO). DESIGN:Perspective. METHODS:A literature search to retrieve original articles, letters, editorials, and published lectures from 1966 to 2017, providing a 50-year review. Titles were excluded that gave no re...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.ajo.2018.03.004
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To screen a population with primary open-angle glaucoma for mutations in the gene that encodes the trabecular meshwork inducible glucocorticoid response protein (TIGR), also known as myocilin (MYOC). METHODS:Ophthalmologic information was collected for study subjects with primary open-angle glaucoma and their ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00536-5
更新日期：2000-08-01 00:00:00
abstract：PURPOSE:To determine whether the risk of graft failure in patients with glaucoma is dependent on the indication for penetrating keratoplasty (PK). DESIGN:Retrospective cohort study. METHODS:All patients on the United Kingdom Transplant Registry undergoing their first PK over a 7-year period with at least 1 year of fo...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.08.018
更新日期：2011-02-01 00:00:00
abstract：PURPOSE:To evaluate the ocular biometric parameters associated with intraocular pressure (IOP) reduction after phacoemulsification. DESIGN:Prospective, observational case series. METHODS:The study included 999 patients who had undergone uncomplicated phacoemulsification. IOP and ocular biometric parameters were check...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.02.003
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:To report the results of a Latin American consensus panel regarding the diagnosis and management of primary open-angle glaucoma and to compare these results with those from a similar panel in the United States. DESIGN:A RAND-like (Research and Development) appropriateness methodology was used to assess glaucom...
journal_title：American journal of ophthalmology
pub_type： 共识发展会议,杂志文章
doi：10.1016/j.ajo.2012.03.015
更新日期：2012-09-01 00:00:00
abstract：PURPOSE:To analyze the comparative safety and efficacy of two techniques of corneal neurotization (CN) (direct corneal neurotization [DCN] vs indirect corneal neurotization [ICN]) for the treatment of neurotrophic keratopathy (NK). DESIGN:Multicenter interventional prospective comparative case series. METHODS:This st...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2020.07.003
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To evaluate low- vs high-dose plaque brachytherapy for juxtapapillary choroidal melanoma. DESIGN:Retrospective interventional case series. METHODS:Setting: Single institution. STUDY POPULATION:Forty-seven patients with juxtapapillary choroidal melanoma. INTERVENTION:Iodine-125 plaque brachytherapy. Eyes wer...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.11.008
更新日期：2018-02-01 00:00:00
abstract：:A 65-year-old white man had an unusual disseminated lymphoid tumor that first appeared in the subconjunctival tissues of the right eye. The tumor later appeared in the skin, lymph nodes, and left upper eyelid and orbit. A monoclonal serum IgA spike was present although the urine did not contain Bence Jones proteins. T...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90082-3
更新日期：1975-02-01 00:00:00
abstract：PURPOSE:To document and study the relationship between perimetric sensitivity and retinal thickness at the foveal and parafoveal points in eyes with macular edema associated with branch retinal vein occlusion. METHODS:A prospective study was performed using the central 10-2 Humphrey perimetry program and optical coher...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00722-4
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To assess the clinical outcomes of conventional and wavefront-guided myopic laser in situ keratomileusis (LASIK) retreatment. DESIGN:Retrospective, nonrandomized case series. METHODS:The study comprised a cohort of 97 eyes having LASIK retreatment for residual myopia after primary LASIK. The eyes were divided...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.11.011
更新日期：2006-04-01 00:00:00
abstract：:Immunofluorescence, histological, and electron microscopic observations were made on rabbit corneas from animals with experimentally induced stromal keratitis following intracorneal injection with the RE strain of herpes simplex virus. Electron microscopic observations were also made on human corneas obtained from pat...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(76)90057-x
更新日期：1976-12-01 00:00:00
abstract：PURPOSE:To report the visual outcome of multiple laser treatments for macular edema attributable to branch retinal vein occlusions (BRVO) and to determine if any prognostic factors exist for improvement. DESIGN:Retrospective chart review. METHODS:A private practice with four vitreoretinal surgeons performed laser tre...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.11.011
更新日期：2005-04-01 00:00:00
abstract：PURPOSE:To compare three phacoemulsification machines for measurement accuracy and postocclusion surge (POS) in human cadaver eyes. DESIGN:In vitro comparisons of machine accuracy and POS. METHODS:Tip vacuum and flow were compared with machine indicated vacuum and flow. All machines were placed in two human cadaver e...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.01.024
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:To report the successful use of topical linezolid 0.2% in the treatment of gram-positive bacterial keratitis. STUDY DESIGN:Retrospective, interventional case series. METHODS:All cases of bacterial keratitis treated at the University of Illinois Eye and Ear Infirmary with topical linezolid were identified from...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.01.010
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To evaluate the complications associated with the primary placement of a motility coupling post (MCP) in spherical porous polyethylene (PP) implants at the time of enucleation. DESIGN:Retrospective, interventional case series. METHODS:The records of all patients who had undergone primary enucleation and spher...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.01.049
更新日期：2007-05-01 00:00:00
abstract：PURPOSE:To report the results and complications of an aspiration cutter-assisted anterior segment tumor biopsy performed under viscoelastic. DESIGN:Retrospective, consecutive, interventional case series. METHODS:Fifty-five patients with anterior segment tumors underwent aspiration cutter-assisted biopsy at a single c...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.04.032
更新日期：2011-11-01 00:00:00
abstract：PURPOSE:To compare the long-term surgical outcomes of augmented bilateral lateral rectus (LR) recession with original surgery. DESIGN:Retrospective, nonrandomized clinical study. METHODS:A total of 447 children with ≤35 prism diopters (PD) of basic and divergence excess-type intermittent exotropia, who underwent orig...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.12.003
更新日期：2016-03-01 00:00:00
abstract：:Four patients observed for a three- to four-year period had a hole in an epiretinal membrane overlying the macula that mimicked a macular hole. In two patients the clinical appearance remained essentially constant. In one, the epiretinal membrane contracted further, reducing the apparent macular hole to a slit and cau...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(76)90002-7
更新日期：1976-11-01 00:00:00
abstract：PURPOSE:To report the cases of four patients with hepatitis C virus infection who experienced clinical features that are virtually identical to Vogt-Koyanagi-Harada disease (VKH). DESIGN:Retrospective observational case series. METHODS:Medical records of patients who were referred between January and December 2003 we...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.06.020
更新日期：2005-11-01 00:00:00
abstract：PURPOSE:Assessment of anterior segment-optical coherence tomography angiography (AS-OCTA) to determine severity of corneal neovascularization (CoNV). DESIGN:Retrospective, cross-sectional, single-center study. METHODS:Patients of various CoNV etiologies were selected and classified into mild, moderate, and severe. Th...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.08.023
更新日期：2020-08-18 00:00:00
abstract：:Eight aniridic patients with bilateral corneal scarring, vascularization, or edema underwent corneal transplantation in one or both eyes (11 eyes). Follow-up ranged from eight months to 5 1/2 years (average, three years). Six of 11 eyes (55%) had at least a two-line improvement in visual acuity and eight of 11 (73%) h...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73581-0
更新日期：1993-03-15 00:00:00
abstract：:We studied four patients with idiopathic dilated episcleral vessels. Three of these patients had asymmetric or unilateral open-angle glaucoma in the eye with the greater degree of episcleral vascular anomaly. The fourth patient showed dilated episcleral vessels, but the intraocular pressure (IOP) was not increased. In...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90010-7
更新日期：1978-07-01 00:00:00
