Two different variants of the same tropomyosin polypeptide in clones from GM1386 human skin fibroblasts.

abstract：:The p21(WAF-1) promoter contains binding sites for a number of transcription factors which mediate its activation by a variety of external signals. Moreover, it has been reported that the transcription factors involved in p21(WAF-1) activation by certain signaling factors, like the phorbol ester TPA, may vary in diffe...

journal_title：Biochemical and biophysical research communications

authors： Schavinsky-Khrapunsky Y,Huleihel M,Aboud M,Torgeman A

更新日期：2003-05-16 00:00:00

abstract：:12-O-tetradecanoyl phorbol 13-acetate (TPA) and 1,2-dioctanoyl-sn-glycerol (diC8) activate protein kinase C (PKC) in transformed fetal bovine aortic endothelial GM 7373 cells. Both molecules cause a similar increase in membrane-associated PKC activity and in the phosphorylation of a PKC-specific endogenous 87-kDa subs...

journal_title：Biochemical and biophysical research communications

authors： Maier JA,Presta M,Ragnotti G

更新日期：1989-04-28 00:00:00

abstract：:In investigations on self-splicing in the group I intron of the pre-mRNA from the nrdB gene of bacteriophage T4 it was found that 2'-amino-2'-deoxyguanosine can replace guanosine as cofactor. This is the first guanosine-analogue with a modification in the 2'-position and substantial activity in a group I self-splicing...

journal_title：Biochemical and biophysical research communications

authors： Strömberg R,Hahne S,Sjögren AS,Sjöberg BM

更新日期：1992-03-16 00:00:00

abstract：:Methylglyoxal (MG) (pyruvaldehyde) is an endogenous metabolite which is present in increased concentrations in diabetics and implicated in formation of advanced glycosylation end-products (AGEs) and secondary diabetic complications. Carnosine (beta-alanyl-L-histidine) is normally present in long-lived tissues at conce...

journal_title：Biochemical and biophysical research communications

authors： Hipkiss AR,Chana H

更新日期：1998-07-09 00:00:00

abstract：:DC-SIGN, a C-type lectin receptor expressed in dendritic cells (DCs), has been identified as a receptor for human immunodeficiency virus type 1, hepatitis C virus, Ebola virus, cytomegalovirus, dengue virus, and the SARS coronavirus. We used H5N1 pseudotyped and reverse-genetics (RG) virus particles to study their abi...

journal_title：Biochemical and biophysical research communications

authors： Wang SF,Huang JC,Lee YM,Liu SJ,Chan YJ,Chau YP,Chong P,Chen YM

更新日期：2008-09-05 00:00:00

abstract：:Northern hybridization studies showed that the level of ovalbumin mRNA decreases in the oviduct of the Japanese quail after adulthood. In order to find out if this is due to changes in the conformation of the chromatin containing the promoter region of the gene, nuclei of the oviduct of young, adult and old birds were...

journal_title：Biochemical and biophysical research communications

authors： Upadhyay R,Gupta S,Kanungo MS

更新日期：1996-09-13 00:00:00

abstract：:The microbial degradative characteristics of butyl benzyl phthalate (BBP) were investigated by the Gordonia sp. strain MTCC 4818 isolated from creosote-contaminated soil. The test organism can utilize a number of phthalate esters as sole sources of carbon and energy, where BBP was totally degraded within 4 days under ...

journal_title：Biochemical and biophysical research communications

authors： Chatterjee S,Dutta TK

更新日期：2003-09-12 00:00:00

abstract：:The cDNAs for two casein kinase-1 homologs, hhp1 and hhp2, have been isolated from Schizosaccharomyces pombe and characterized. Their corresponding genes reside on chromosomes II and I, respectively, and encode approximately 42-46 kDa proteins that are related structurally to the HRR25 gene product of budding yeast. O...

journal_title：Biochemical and biophysical research communications

authors： Kearney PH,Ebert M,Kuret J

更新日期：1994-08-30 00:00:00

abstract：:Skeletal muscle undergoes complicated differentiation steps that include cell-cycle arrest, cell fusion, and maturation, which are controlled through sequential expression of transcription factors. During muscle differentiation, remodeling of the epigenetic landscape is also known to take place on a large scale, deter...

journal_title：Biochemical and biophysical research communications

authors： Watanabe TM,Higuchi S,Kawauchi K,Tsukasaki Y,Ichimura T,Fujita H

更新日期：2012-02-24 00:00:00

abstract：:Increasing evidences suggest that, after neuregulin (NRG) stimulation, ErbB4 undergoes a series of proteolysis, including gamma-secretase cleavage. The released ErbB4 intracellular domain (EICD) is translocated into nucleus and has a transcriptional function. Although NRG-ErbB4 signaling mediates maturation of oligode...

journal_title：Biochemical and biophysical research communications

authors： Lai C,Feng L

更新日期：2004-02-06 00:00:00

abstract：:The adipose tissue of genetically obese Zucker rats is characterized by coordinated tissue specific overtranscription of a subset of genes related to lipid storage such as Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH). We show that CCAAT/Enhancer Binding Protein alpha (C/EBP alpha) is an activator of GAPDH proximal...

journal_title：Biochemical and biophysical research communications

authors： Rolland V,Le Liepvre X,Houbiguian ML,Lavau M,Dugail I

更新日期：1995-02-15 00:00:00

abstract：:Four new basic proteins were isolated from horse eosinophils and purified. The eosinophils release these proteins after permeabilization with saponin and degranulation stimulized by guanosine 5'-O-thiotriphosphate. The proteins were separated and purified on a Superose P12- and a Mono S-column by fast protein liquid c...

journal_title：Biochemical and biophysical research communications

authors： Piller K,Portmann P

更新日期：1993-04-30 00:00:00

abstract：:Dimerization-induced activation of LXR is a unique allosteric mechanism described only for LXR/RXR heterodimers. Previously, we demonstrated that RXR functions as an allosteric activator of LXR binding to ASC-2 coactivator rather than as a direct interaction partner. Here, we investigated the molecular basis of the in...

journal_title：Biochemical and biophysical research communications

authors： Son YL,Lee YC

更新日期：2009-07-03 00:00:00

abstract：:Recent findings have shown that SLIT2 appears to function as a novel tumor suppressor gene. In addition, hypermethylation of its promoter region has been detected in various cancers, including breast and lung cancer, colorectal carcinoma, and gliomas. Here, we report for the first time that there is epigenetic silenci...

journal_title：Biochemical and biophysical research communications

authors： Jin J,You H,Yu B,Deng Y,Tang N,Yao G,Shu H,Yang S,Qin W

更新日期：2009-01-30 00:00:00

abstract：:We hypothesized that the mutational strand asymmetry is more strongly exerted upon the mitochondrial cytochrome b (Cytb) gene, which is distant from the origin of the light-strand replication (Ori(L)), than upon the ATPase subunit 6 (ATP6) gene, which is close to the Ori(L). To test this hypothesis, we determined the ...

journal_title：Biochemical and biophysical research communications

authors： Fuku N,Oshida Y,Takeyasu T,Guo LJ,Kurata M,Yamada Y,Sato Y,Tanaka M

更新日期：2002-02-01 00:00:00

abstract：:[8]-Gingerol is an active component of Zinger and shows several pharmacological activities, such as antipyretic and anti-inflammation characteristics. To identify a potential skin-whitening agent, the inhibitory effects of [8]-gingerol on melanogenesis and its mechanism of action were investigated. In the present stud...

journal_title：Biochemical and biophysical research communications

authors： Huang HC,Chou YC,Wu CY,Chang TM

更新日期：2013-08-23 00:00:00

abstract：:The short-term incubation of HeLa cells in the presence of diferric transferrin or ferricyanide, which are reduced externally by the transplasma membrane reductase, produces a stoichiometric decrease in NADH and increase in NAD+, which is stimulated by insulin. The NADP/NADPH ratio does not change during 15 min incuba...

journal_title：Biochemical and biophysical research communications

authors： Navas P,Sun IL,Morré DJ,Crane FL

更新日期：1986-02-26 00:00:00

abstract：:Interleukin-6 (IL-6) is a multifunctional cytokine playing roles in the immune system, hematopoiesis, and acute phase reactions. IL-6 also regulates the growth of various types of human malignant tumors. Here we demonstrate that IL-6-induced gene expression was suppressed by a specific heat-shock protein 90 (Hsp90) in...

journal_title：Biochemical and biophysical research communications

authors： Sato N,Yamamoto T,Sekine Y,Yumioka T,Junicho A,Fuse H,Matsuda T

更新日期：2003-01-24 00:00:00

abstract：:Lysophosphatidylcholine (lyso-PC), a biologically active phospholipid, appears to modulate various endothelial cell functions through tyrosine kinase-dependent signaling pathways. In cultured bovine aortic endothelial cells (BAEC), we have found that a 130 kDa protein (p130) was rapidly tyrosine phosphorylated within ...

journal_title：Biochemical and biophysical research communications

authors： Ochi H,Kume N,Nishi E,Moriwaki H,Masuda M,Fujiwara K,Kita T

更新日期：1998-02-24 00:00:00

abstract：:The Rho-associated coiled-coil kinase (ROCK) family of proteins, including ROCK1 and ROCK2, are key regulators of actin and intermediate filament morphology. The newly discovered ROCK substrate Tubulin polymerization promoting protein 1 (TPPP1) promotes microtubule polymerization and inhibits the activity of Histone d...

journal_title：Biochemical and biophysical research communications

authors： Schofield AV,Gamell C,Bernard O

更新日期：2013-07-12 00:00:00

abstract：:Jasmonates are plant lipid-derived oxylipins that act as key signaling compounds in plant immunity, germination, and development. Although some physiological activities of natural jasmonates in mammalian cells have been investigated, their anti-inflammatory actions in mammalian cells remain unclear. Here, we investiga...

journal_title：Biochemical and biophysical research communications

authors： Taki-Nakano N,Kotera J,Ohta H

更新日期：2016-05-13 00:00:00

abstract：:In Dictyostelium discoideum, a novel type of RNA (dutA RNA), which is untranslatable, cytosolic and 1.3 kb in size, appears specifically after the aggregation stage [Yoshida, H. et al. (1994) Nucleic Acids Res. 22, 41-46]. We here show that the dutA gene is transcribed by RNA polymerase II, based on its alpha-amanitin...

journal_title：Biochemical and biophysical research communications

authors： Kumimoto H,Yoshida H,Okamoto K

更新日期：1995-11-02 00:00:00

abstract：:Drosophila melanogaster multisubstrate deoxyribonucleoside kinase (Dm-dNK) can additionally sensitize human cancer cell lines towards the anti-cancer drug gemcitabine. We show that this property is based on the Dm-dNK ability to efficiently phosphorylate gemcitabine. The 2.2A resolution structure of Dm-dNK in complex ...

journal_title：Biochemical and biophysical research communications

authors： Knecht W,Mikkelsen NE,Clausen AR,Willer M,Eklund H,Gojković Z,Piskur J

更新日期：2009-05-01 00:00:00

abstract：:Hippocampal slices offer an excellent experimental system for the study of activity-induced changes in the postsynaptic density (PSD). While studies have documented electrophysiological and structural changes at synapses in response to precise manipulations of hippocampal slices, parallel biochemical and proteomic ana...

journal_title：Biochemical and biophysical research communications

authors： Dosemeci A,Tao-Cheng JH,Vinade L,Jaffe H

更新日期：2006-01-13 00:00:00

abstract：:The activation of Kupffer cells represents a central mechanism of liver injury involving the production of TNF-alpha. It is known that glycine prevents LPS-induced production of TNF-alpha in isolated Kupffer cells. In this study, the possibility that glycine analogues might affect Kupffer cells was investigated. As a ...

journal_title：Biochemical and biophysical research communications

authors： Ishizaki-Koizumi S,Sonaka I,Takei Y,Ikejima K,Sato N

更新日期：2004-09-17 00:00:00

abstract：:Here we demonstrate that the semi-synthetic flavonoid ayanin diacetate induces cell death selectively in leukemia cells without affecting the proliferation of normal lymphocytes. Incubation of human leukemia cells with ayanin diacetate induced G(2)-M phase cell cycle arrest and apoptosis which was prevented by the non...

journal_title：Biochemical and biophysical research communications

authors： Marrero MT,Estévez S,Negrín G,Quintana J,López M,Pérez FJ,Triana J,León F,Estévez F

更新日期：2012-11-09 00:00:00

abstract：:Matrin 3, a nuclear matrix protein has potential (1) to withhold promiscuously edited RNAs within the nucleus in cooperation with p54(nrb) and PSF, (2) to mediate NMDA-induced neuronal death, and (3) to modulate promoter activity of genes proximal to matrix/scaffold attachment region (MAR/SAR). We identified a biparti...

journal_title：Biochemical and biophysical research communications

authors： Hisada-Ishii S,Ebihara M,Kobayashi N,Kitagawa Y

更新日期：2007-03-02 00:00:00

abstract：:We investigated the role of acyl-CoAs during induction and maintenance of long-term potentiation in rat brain hippocampus. Changes of acyl-CoA and free fatty acids (FFA) in hippocampus were measured during tetraethylammonium (TEA)-induced LTP. Results indicated that concentrations of acyl-CoAs and FFAs in slices were ...

journal_title：Biochemical and biophysical research communications

authors： Zhang Q,Yoshida S,Sakai K,Liu J,Fukunaga K

更新日期：2000-01-07 00:00:00

abstract：BACKGROUND:The functionality of lncRNA snaR has only been characterized in breast cancer and colon cancer. The aim of the current study is to explore the involvement of lncRNA snaR in ovarian carcinoma (OC). MATERIALS AND METHODS:Expression of lncRNA snaR and GRB2-associated binding protein 2 (GAB2) in plasma of both ...

journal_title：Biochemical and biophysical research communications

authors： Huang Y,Hu Y,Jin Z,Shen Z

更新日期：2018-09-10 00:00:00

abstract：:A general method to obtain the variable region DNA sequence of the immunoglobulin heavy chain using anchored polymerase chain reaction is described. Based on this DNA sequence, clone-specific oligonucleotides were designed to anneal to the complementarity determining regions. These were used to identify the original B...

journal_title：Biochemical and biophysical research communications

authors： Ratech H

更新日期：1992-02-14 00:00:00