Restoration of defective EAG-rosetting capacity of cancer patient neutrophils by levamisole.

abstract：:The German Society of Pediatric Oncology in 1981 initiated the Cooperative Ewing's Sarcoma Study (CESS 81) using a four-drug combination of chemotherapy prior to definitive local control with surgery and/or radiation. From January 1, 1981 until February 28, 1985, 93 patients were registered at the trial office from 54...

journal_title：Cancer

authors： Jürgens H,Exner U,Gadner H,Harms D,Michaelis J,Sauer R,Treuner J,Voûte T,Winkelmann W,Winkler K

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Although outcomes for patients with squamous cell carcinoma of the anus (SCCA) have improved, the gains in benefit may not be shared uniformly among patients of disparate socioeconomic status. In the current study, the authors investigated whether area-based median household income (MHI) is predictive of sur...

journal_title：Cancer

authors： Lin D,Gold HT,Schreiber D,Leichman LP,Sherman SE,Becker DJ

更新日期：2018-04-15 00:00:00

abstract：BACKGROUND:Systemic, high-dose interferon-alpha treatment given three times per week subcutaneously induces tumor regression in approximately 30% of patients with inoperable hepatocellular carcinoma (HCC). The objective of the current study was to determine the efficacy and safety of transcatheter arterial interferon e...

journal_title：Cancer

authors： Yuen MF,Ooi CG,Hui CK,Wong WM,Wong BC,Chan AO,Lai CL

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:A retrospective clinicopathologic study was performed to identify the influence of diagnostic and therapeutic procedures on the outcomes of patients with the follicular variant of papillary thyroid carcinoma (FVPTC). METHODS:The results of 37 patients with FVPTC were compared with those of 37 randomly selec...

journal_title：Cancer

authors： Tielens ET,Sherman SI,Hruban RH,Ladenson PW

更新日期：1994-01-15 00:00:00

abstract：:This study attempted to determine the relationship of nutritional status, menopausal status, presence of breast cancer, stage of disease, and tumor estrogen receptor levels to percent non-protein-bound estradiol (%NPBE) and percent distribution of estradiol on sex hormone-binding globulin (SHBG) and albumin in breast ...

journal_title：Cancer

authors： Ota DM,Jones LA,Jackson GL,Jackson PM,Kemp K,Bauman D

更新日期：1986-02-01 00:00:00

abstract：:In view of increasing debate over possible benefit of more complete surgery compared to conservative procedures, a randomized controlled trial contrasting the then standard Halsted radical (RDL) operation with the more complete extended radical (EXT) mastectomy was initiated in 1973. Between November 1973 and July 198...

journal_title：Cancer

authors： Meier P,Ferguson DJ,Karrison T

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The incidence, risk factors, time course, and impact on survival of venous thromboembolism (VTE) in a large, population-based study of patients with bladder cancer have not been identified previously. METHODS:The California Cancer Registry was merged with the California Patient Discharge Data Set to determi...

journal_title：Cancer

authors： Sandhu R,Pan CX,Wun T,Harvey D,Zhou H,White RH,Chew HK

更新日期：2010-06-01 00:00:00

abstract：:The glucocorticoid receptor (GR) quantitation by a whole-cell assay and/or cytosol technique and the in vitro sensitivity to steroids have been assessed in peripheral blood cells from normal donors and patients with chronic lymphatic leukemia (CLL), acute lymphoblastic leukemia (ALL), lymphosarcoma cell leukemia (LSCL...

journal_title：Cancer

authors： Nanni P,Nicoletti G,Prodi G,Galli MC,De Giovanni C,Grilli S,Lollini PL,Gobbi M,Cavo M,Tura S

更新日期：1982-02-15 00:00:00

abstract：BACKGROUND:The p53 tumor suppressor gene encodes a nuclear phosphoprotein that is thought to be important to cell cycle regulation and DNA repair and that also may regulate induction of apoptosis by ionizing radiation. Somatic p53 gene mutations occur in 30-50% of breast carcinomas and are associated with poor prognosi...

journal_title：Cancer

authors： Turner BC,Gumbs AA,Carbone CJ,Carter D,Glazer PM,Haffty BG

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:The objective of this article was to report the results from a randomized clinical trial comparing intensity-modulated radiotherapy (IMRT) with 3-dimensonal conformal radiotherapy (3DCRT) for the treatment of prostate cancer on a hypofractionated schedule. METHODS:The authors randomly assigned 215 men who h...

journal_title：Cancer

authors： Viani GA,Viana BS,Martin JE,Rossi BT,Zuliani G,Stefano EJ

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:The capacity of neonatal sacrococcygeal teratomas (SCT) to recur is a well-recognized phenomenon. However, only a few studies have reported recurrence of the tumors beyond childhood. METHODS:A follow-up of patients for the detection of late recurrent SCT was performed in 45 patients, ages 4-43 years (mean, ...

journal_title：Cancer

authors： Lahdenne P,Heikinheimo M,Nikkanen V,Klemi P,Siimes MA,Rapola J

更新日期：1993-12-15 00:00:00

abstract：:Esophageal dilation by means of guided Neoplex (Medoc) tubes in 38 patients with malignant obstruction of the esophagus was analyzed. Peroral dilation proved to be a simple, well-tolerated primary procedure in the management of malignant strictures. Most patients have a temporary improvement of dysphagic symptoms, but...

journal_title：Cancer

authors： Aste H,Munizzi F,Martines H,Pugliese V

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:It is challenging for clinicians to foster coping and allow hope when discussing prognosis and end-of-life (EOL) issues with terminally ill cancer patients and their caregivers. To the authors' knowledge, little research evidence is currently available to guide clinical practice. METHODS:The authors conduct...

journal_title：Cancer

authors： Clayton JM,Butow PN,Arnold RM,Tattersall MH

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Radioimmunotherapy with radiolabeled monoclonal antibodies to CD20 produces a high response rate in patients with recurring non-Hodgkin lymphoma (NHL), but the durability of those remissions is not well defined. METHODS:Data on patients with recurring NHL treated with yttrium Y 90 ibritumomab tiuxetan in 4 ...

journal_title：Cancer

authors： Witzig TE,Molina A,Gordon LI,Emmanouilides C,Schilder RJ,Flinn IW,Darif M,Macklis R,Vo K,Wiseman GA

更新日期：2007-05-01 00:00:00

abstract：:Histologic examination of bone-marrow from the posterior iliac crest was routinely done as a pretreatment staging procedure in 203 consecutive patients with small-cell anaplastic carcinoma of the lung. Subtyping of the patients according to the WHO classification included 27.8% with "fusiform" cell type (WHO II,1), 28...

journal_title：Cancer

authors： Hirsch F,Hansen HH,Dombernowsky P,Hainau B

更新日期：1977-06-01 00:00:00

abstract：:We have reviewed the records of 76 patients with Stage I or II extranodal non-Hodgkin's lymphoma who were referred to the Division of Radiation Oncology, Mallinckrodt Institute of Radiology, during the years 1964 through 1974. The histologic slides were reviewed in the 67 cases in which they were available. Forty-thre...

journal_title：Cancer

authors： Mill WB,Lee FA,Franssila KO

更新日期：1980-02-15 00:00:00

abstract：:Alkylating agents form the basis of most combination treatment regimens for low-grade lymphoproliferative disorders. Bendamustine is a unique alkylating agent that has distinctive preclinical activity in cell lines resistant to other alkylators. Furthermore, clinical activity has been demonstrated in patients with alk...

journal_title：Cancer

authors： Kalaycio M

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:In oligodendroglial tumors, allelic losses on chromosome arms 1p and 19q are not only diagnostic molecular markers but also statistically significant predictors of both chemosensitivity and longer recurrence-free survival. In the current study, the authors attempted to analyze 21 patients genetically and cli...

journal_title：Cancer

authors： Hashimoto N,Murakami M,Takahashi Y,Fujimoto M,Inazawa J,Mineura K

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:There is no standard therapy for surgery- and radiotherapy-resistant, recurrent, low-grade spinal cord gliomas. Therefore, a retrospective study of temozolomide (TMZ) in adults with recurrent low-grade spinal cord gliomas with a primary objective of determining progression-free survival (PFS) was performed. ...

journal_title：Cancer

authors： Chamberlain MC

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Patients affected by neurofibromatosis type 1 (NF1) are at higher risk of developing soft-tissue sarcomas (STS) than the general population. The clinical findings and outcome in 43 children and adolescents with NF1 treated for STS in the Italian protocols between 1988 and 2004 are reported. METHODS:The stud...

journal_title：Cancer

authors： Ferrari A,Bisogno G,Macaluso A,Casanova M,D'Angelo P,Pierani P,Zanetti I,Alaggio R,Cecchetto G,Carli M

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:To assess the ability of [(18)F]fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET) to predict the viability of residual masses after chemotherapy in patients with metastatic nonseminomatous germ cell tumors (GCT), PET results were compared in a blinded analysis with computed tomography (CT) sca...

journal_title：Cancer

authors： Kollmannsberger C,Oechsle K,Dohmen BM,Pfannenberg A,Bares R,Claussen CD,Kanz L,Bokemeyer C

更新日期：2002-05-01 00:00:00

abstract：:Fifty-three patients with advanced lymphocytic lymphoma were randomly assigned to treatment with the combination cyclophosphamide, vincristine, and prednisone (CVP) or the same agents used successively in maximal doses (C-V-P). Complete remissions occurred in 68% with CVP and 48% with C-V-P. For patients with nodular ...

journal_title：Cancer

authors： Kennedy BJ,Bloomfield CD,Kiang DT,Vosika G,Peterson BA,Theologides A

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Adult "translocation" renal cell carcinoma (RCC), bearing transcription factor E3 (TFE3) gene fusions at Xp11.2, is a recently recognized, unique entity for which prognosis and therapy remain poorly understood. In the current study, the authors investigated the effect of vascular endothelial growth factor (V...

journal_title：Cancer

authors： Choueiri TK,Lim ZD,Hirsch MS,Tamboli P,Jonasch E,McDermott DF,Dal Cin P,Corn P,Vaishampayan U,Heng DY,Tannir NM

更新日期：2010-11-15 00:00:00

abstract：:If radical surgery is the only rational policy for most cases of rectal cancer, the problem of local treatment in poor surgical risk patients should be discussed in selected cases. Only limited, fairly-well-differentiated tumors, still confined to the rectal wall may have a sufficiently low probability of lymphatic sp...

journal_title：Cancer

authors： Papillon J

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:The degree of response and the duration of survival of patients treated with mitogen-activated protein kinase (MAPK) inhibitors are highly variable. Whether baseline clinicopathologic factors can predict the clinical course with treatment is largely unknown. METHODS:For 142 consecutive immunotherapy- and MA...

journal_title：Cancer

authors： Menzies AM,Wilmott JS,Drummond M,Lo S,Lyle M,Chan MM,Thompson JF,Guminski A,Carlino MS,Scolyer RA,Kefford RF,Long GV

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:In the phase 3 MARIANNE trial, trastuzumab emtansine (T-DM1) with or without pertuzumab showed noninferior progression-free survival and better tolerability than trastuzumab plus a taxane (HT) for the first-line treatment of human epidermal growth factor receptor 2 (HER2)-positive advanced breast cancer. Thi...

journal_title：Cancer

authors： Perez EA,Barrios C,Eiermann W,Toi M,Im YH,Conte P,Martin M,Pienkowski T,Pivot XB,Burris HA 3rd,Petersen JA,De Haas S,Hoersch S,Patre M,Ellis PA

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND:The current study was conducted to characterize the epidemiology, histology, and radiographic features of as well as the surgical approach to pediatric and adolescent renal cell carcinoma (pRCC). METHODS:pRCC cases prospectively enrolled on the Children's Oncology Group study AREN03B2 underwent central path...

journal_title：Cancer

authors： Geller JI,Ehrlich PF,Cost NG,Khanna G,Mullen EA,Gratias EJ,Naranjo A,Dome JS,Perlman EJ

更新日期：2015-07-15 00:00:00

abstract：BACKGROUND:An association between laryngopharyngeal reflux (LPR) and laryngeal carcinoma has been suggested, but remains unproven. The current pilot study was performed to determine the incidence of LPR among patients with early laryngeal carcinomas or dysplasia and to examine the associations between levels of LPR and...

journal_title：Cancer

authors： Lewin JS,Gillenwater AM,Garrett JD,Bishop-Leone JK,Nguyen DD,Callender DL,Ayers GD,Myers JN

更新日期：2003-02-15 00:00:00

abstract：:A summary is presented of those organ specific enzyme assays traditionally used in evaluation of the patient with cancer. In addition, the use of certain serum enzymes such as gamma-glutamyl transpeptidase, phosphohexose isomerase or 5'-nucleotidase as aids in following the course of the disease, particularly in patie...

journal_title：Cancer

authors： Schwartz MK

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNAB) has been used with variable success as a diagnostic test for benign and malignant breast lesions. The goal of this study was to examine the effects of training physicians in the fine-needle aspiration sampling-technique on the diagnostic accuracy of FNAB of palpable breas...

journal_title：Cancer

authors： Ljung BM,Drejet A,Chiampi N,Jeffrey J,Goodson WH 3rd,Chew K,Moore DH 2nd,Miller TR

更新日期：2001-08-25 00:00:00