Cholestane and spirostane glycosides from the rhizomes of Dioscorea septemloba.

Abstract:

:Cholestane glycosides, dioseptemlosides A (1) and B (2), together with six spirostane glycosides, dioseptemlosides C-H (3-8), were isolated from the rhizomes of Dioscorea septemloba. Their structures were established on the basis of physical data, spectroscopic analysis (HRESIMS, 1D and 2D NMR), and chemical methods. Spirostane aglcones containing hydroxyl group at C-7, as found in compounds 4-7, were reported in the family Dioscoreaceae for the first time. These compounds did not show considerable inhibitory anti-tumor activities at a concentration of 10 microM.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Liu XT,Wang ZZ,Xiao W,Zhao HW,Hu J,Yu B

doi

10.1016/j.phytochem.2007.12.014

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

1411-8

issue

6

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(08)00003-4

journal_volume

69

pub_type

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