Abstract:
:Four cycloartane-type saponins, kahiricosides II-V (1-4), were isolated from the aerial parts of Astragalus kahiricus of Egyptian origin. Their structures were established as 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-beta-D-glucopyranoside, 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-(2'-O-acetyl)-beta-D-glucopyranoside, 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-(6'-O-acetyl)-beta-D-glucopyranoside, and 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-beta-D-glucopyranosyl-27-O-beta-D-glucopyranoside based on chemical and spectral evidences. All compounds exhibited very weak cytotoxicity against the A2780 ovarian cancer cell line.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Radwan MM,El-Sebakhy NA,Asaad AM,Toaima SM,Kingston DGdoi
10.1016/j.phytochem.2004.08.037subject
Has Abstractpub_date
2004-11-01 00:00:00pages
2909-13issue
21eissn
0031-9422issn
1873-3700pii
S0031-9422(04)00418-2journal_volume
65pub_type
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