Ambulatory Holter electrocardiography: choice of technologies and clinical uses.

abstract：:In recent years there has been increasing attention to the appropriate interpretation of a clinical study. One special concern has been the difficulty inherent in interpreting studies that were not statistically significant: Was the sample size sufficient to detect a clinically important effect if, in fact, it existed...

journal_title：Annals of internal medicine

authors： Young MJ,Bresnitz EA,Strom BL

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVE:To determine which procedures nephrologists do in practice, where they learned the procedures, and how much training they recommend to achieve and maintain clinical competence in each. DESIGN:Mailed survey. PARTICIPANTS:A random sample of 700 members of the American College of Physicians who were identified...

journal_title：Annals of internal medicine

authors： Tape TG,Wigton RS,Blank LL,Nicolas JA

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:A common criticism of randomized, controlled trials (RCTs) is that the enrollment process may be highly selective and those who enroll may not represent persons in the general population. The recruitment process reported in published RCTs has not been systematically evaluated. OBJECTIVE:To determine whether...

journal_title：Annals of internal medicine

authors： Gross CP,Mallory R,Heiat A,Krumholz HM

更新日期：2002-07-02 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of fluconazole for prevention of fungal infections. DESIGN:A randomized, placebo-controlled, double-blind, multicenter trial. PATIENTS:Adults (257) undergoing chemotherapy for acute leukemia. INTERVENTION:Patients were randomly assigned to receive either fluconazole (400...

journal_title：Annals of internal medicine

authors： Winston DJ,Chandrasekar PH,Lazarus HM,Goodman JL,Silber JL,Horowitz H,Shadduck RK,Rosenfeld CS,Ho WG,Islam MZ,Buell DN

更新日期：1993-04-01 00:00:00

abstract：:To characterize the role of cardiac function in septic shock, serial radionuclide cineangiographic and hemodynamic evaluations were done on 20 patients with documented septic shock. Although all patients had a normal or elevated cardiac index, 10 patients had moderate to severe depression of their ejection fraction wi...

journal_title：Annals of internal medicine

authors： Parker MM,Shelhamer JH,Bacharach SL,Green MV,Natanson C,Frederick TM,Damske BA,Parrillo JE

更新日期：1984-04-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the sensitivity of herpes simplex virus isolates to acyclovir and the importance of resistant isolates in hospitalized patients. DESIGN:Retrospective incidence cohort study. SETTING:All herpes simplex virus isolates cultured over 1 year from patients followed at a tertiary care center. P...

journal_title：Annals of internal medicine

authors： Englund JA,Zimmerman ME,Swierkosz EM,Goodman JL,Scholl DR,Balfour HH Jr

更新日期：1990-03-15 00:00:00

abstract：:We studied D-penicillamine toxicity in 259 patients with systemic sclerosis treated since 1972. The average daily dose of 635 mg was given for a mean of 1.8 years. Of patients with systemic sclerosis, 47% has side effects from D-penicillamine treatment, similar to the 56% of 807 patients with rheumatoid arthritis in s...

journal_title：Annals of internal medicine

authors： Steen VD,Blair S,Medsger TA Jr

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Screening mammography is recommended for women 50 to 69 years of age because of its proven efficacy and reasonable cost-effectiveness. Extending screening recommendations to include women 40 to 49 years of age remains controversial. OBJECTIVE:To compare the cost-effectiveness of screening mammography in wom...

journal_title：Annals of internal medicine

authors： Salzmann P,Kerlikowske K,Phillips K

更新日期：1997-12-01 00:00:00

abstract：:In addition to gonorrhea and syphilis, both of which may develop primarily at anorectal or pharyngeal sites, a number of conditions, including Neisseria meningitidis urethritis, nonspecific urethritis, anorectal herpes, condyloma acuminatum, amebiasis, giardiasis, shigellosis, typhoid fever, enterobiasis, and hepatiti...

journal_title：Annals of internal medicine

authors： Owen WF Jr

更新日期：1980-06-01 00:00:00

abstract：:To assess the course and prognosis of salicylate-induced pulmonary edema, we reviewed the records of 36 consecutive patients admitted with serum salicylate levels greater than 30 mg/dL. Pulmonary edema developed in eight patients, and pulmonary infiltrates were never seen in 28 patients. Several features distinguished...

journal_title：Annals of internal medicine

authors： Heffner JE,Sahn SA

更新日期：1981-10-01 00:00:00

abstract：STUDY OBJECTIVE:To test the hypothesis that work as a respiratory therapist is associated with an increased risk of developing asthma. DESIGN:Cross-sectional questionnaire study comparing respiratory therapists with controls (physical therapists and radiologic technologists). Subsequent validation of reported asthma w...

journal_title：Annals of internal medicine

authors： Kern DG,Frumkin H

更新日期：1989-05-15 00:00:00

abstract：:To increase the utility of administrative databases, it has been recommended that they include disease-specific, patient-centered outcome measures. This paper reviews practical and theoretical considerations and the critical evidence to support this recommendation. The strengths and weaknesses of the recommended appro...

journal_title：Annals of internal medicine

authors： Liang MH,Shadick N

更新日期：1997-10-15 00:00:00

abstract：OBJECTIVE:To define the incidence of and possible risk factors for invasive Haemophilus influenzae disease in adults. DESIGN:Prospective, population-based surveillance of hospital and referral bacteriology laboratories. SETTING:Metropolitan Atlanta, Georgia community. PATIENTS:All patients with H. influenzae isolate...

journal_title：Annals of internal medicine

authors： Farley MM,Stephens DS,Brachman PS Jr,Harvey RC,Smith JD,Wenger JD

更新日期：1992-05-15 00:00:00

abstract：:Vasodilator drugs were initially administered to patients with primary pulmonary hypertension based on the unproven hypothesis that pulmonary vasoconstriction played an important role in the pathogenesis of the disease. There were early reports of hemodynamic and clinical improvement after treatment with various vasod...

journal_title：Annals of internal medicine

authors： Packer M

更新日期：1985-08-01 00:00:00

abstract：:Between 1 January 1980 and 18 October 1981, investigators from the Centers for Disease Control collected information on 1407 cases of toxic shock syndrome using a nationwide passive surveillance system. Ninety-two percent of the reported cases were associated with menstruation. Information available on the type of men...

journal_title：Annals of internal medicine

authors： Reingold AL,Hargrett NT,Shands KN,Dan BB,Schmid GP,Strickland BY,Broome CV

更新日期：1982-06-01 00:00:00

abstract：DESCRIPTION:New recommendation from the U.S. Preventive Services Task Force (USPSTF) on the use of nontraditional, or novel, risk factors in assessing the coronary heart disease (CHD) risk of asymptomatic persons. METHODS:Systematic reviews were conducted of literature since 1996 on 9 proposed nontraditional markers o...

journal_title：Annals of internal medicine

authors： U.S. Preventive Services Task Force.

更新日期：2009-10-06 00:00:00

abstract：:Increased adrenocorticotropic hormone (ACTH) levels after bilateral adrenalectomy could be secondary to a pituitary tumor, under replacement with cortisol, or an abnormality in the hypothalamic-pituitary-adrenal feedback loop. To distinguish between these possibilities, ACTH levels were measured before and after corti...

journal_title：Annals of internal medicine

authors： Koletsky RJ,Dluhy RG,Crantz FR,Williams GH

更新日期：1982-03-01 00:00:00

abstract：:The expression of ischemic heart disease was studied in a large kindred with familial hypercholesterolemia. Tendon xanthomas, multiple generation transmission, and the appearance of bimodality in the distributions of total and low-density lipoprotein cholesterol were found. The segregation ratio was 0.9 in females and...

journal_title：Annals of internal medicine

authors： Streja D,Steiner G,Kwiterovich PO Jr

更新日期：1978-12-01 00:00:00

abstract：:Poststreptococcal acute glomerulonephritis is prototypic of the immunologic glomerulonephritides. It most commonly follows streptococcal infection of the pharynx or skin. The diagnosis is usually not difficult when a nephritic clinical presentation (with such manifestations as hematuria, edema, and hypertension) is as...

journal_title：Annals of internal medicine

authors： Nissenson AR,Baraff LJ,Fine RN,Knutson DW

更新日期：1979-07-01 00:00:00

abstract：PURPOSE:To review epidemiologic studies on the association between homocyst(e)ine level and risk for cardiovascular disease and the potential benefits of homocysteine-decreasing therapies. DATA SOURCES:Computerized and manual searches of the literature on total homocysteine levels and cardiovascular disease. STUDY SE...

journal_title：Annals of internal medicine

authors： Eikelboom JW,Lonn E,Genest J Jr,Hankey G,Yusuf S

更新日期：1999-09-07 00:00:00

abstract：:Under the current system of disability determination and workers' compensation for occupational lung disease, disabled workers or their survivors can reasonably count on being compensated. However, by rejecting established scientific truth in order to pay workers' compensation in circumstances where disability or deat...

journal_title：Annals of internal medicine

authors： Richman SI

更新日期：1982-12-01 00:00:00

abstract：OBJECTIVE:To validate prospectively the use of an artificial neural network to identify myocardial infarction in patients presenting to an emergency department with anterior chest pain. DESIGN:Prospective, blinded testing. SETTING:Tertiary university teaching center. PATIENTS:A total of 331 consecutive adult patient...

journal_title：Annals of internal medicine

authors： Baxt WG

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVES:To determine the distribution of and risk factors for colonization and infection with vancomycin-resistant enterococci; to evaluate the molecular epidemiology of these strains; and to assess the effect of interventions, including 1) strict adherence to infection control procedures and 2) restricted use of va...

journal_title：Annals of internal medicine

authors： Morris JG Jr,Shay DK,Hebden JN,McCarter RJ Jr,Perdue BE,Jarvis W,Johnson JA,Dowling TC,Polish LB,Schwalbe RS

更新日期：1995-08-15 00:00:00

abstract：OBJECTIVE:To determine the toxicity and efficacy of low-dose interferon-alpha therapy in inducing remissions and prolonging survival in patients with chronic myeloid leukemia. DESIGN:Phase II evaluation and comparison with historical control patients and other series in which the investigators used higher interferon-a...

journal_title：Annals of internal medicine

authors： Schofield JR,Robinson WA,Murphy JR,Rovira DK

更新日期：1994-11-15 00:00:00

abstract：:A cohort of both active and retired older cotton textile workers was examined prospectively over a 6-year period to establish the nature and extent of chronic lung disease. Respiratory symptoms and lung function were studied in these workers and in a group of similarly aged controls. The cotton textile workers had hig...

journal_title：Annals of internal medicine

authors： Beck GJ,Schachter EN,Maunder LR,Schilling RS

更新日期：1982-11-01 00:00:00

abstract：:Bioethics has become a common course of study in medical schools, other health professional schools, and graduate and undergraduate programs. An analysis of past ethical scandals, as well as the bioethics apparatus that emerged in response to them, is often central to the discussion of bioethical questions. This histo...

journal_title：Annals of internal medicine

authors： Lerner BH,Caplan AL

更新日期：2016-04-19 00:00:00

abstract：BACKGROUND:The accuracy and harms of brief cognitive tests for identifying clinical Alzheimer-type dementia (CATD) are uncertain. PURPOSE:To summarize evidence on accuracy and harms of brief cognitive tests for CATD in older adults with suspected cognitive impairment. DATA SOURCES:Electronic bibliographic databases (...

journal_title：Annals of internal medicine

authors： Hemmy LS,Linskens EJ,Silverman PC,Miller MA,Talley KMC,Taylor BC,Ouellette JM,Greer NL,Wilt TJ,Butler M,Fink HA

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:Pharmaceutical companies and other trial sponsors must submit certain trial results to ClinicalTrials.gov. The validity of these results is unclear. PURPOSE:To validate results posted on ClinicalTrials.gov against publicly available U.S. Food and Drug Administration (FDA) reviews on Drugs@FDA. DATA SOURCES...

journal_title：Annals of internal medicine

authors： Schwartz LM,Woloshin S,Zheng E,Tse T,Zarin DA

更新日期：2016-09-20 00:00:00

abstract：:Meta-analysis is the process of combining study results that can be used to draw conclusions about therapeutic effectiveness or to plan new studies. We review important design and statistical issues of this process. The design issues include protocol development, objectives, literature search, publication bias, measur...

journal_title：Annals of internal medicine

authors： L'Abbé KA,Detsky AS,O'Rourke K

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:The high prevalence of classic cardiac risk factors in patients with non-insulin-dependent diabetes mellitus does not explain the increased cardiovascular-related morbidity and mortality in these patients. Fibrinogen may have a role in this excess risk. OBJECTIVE:To evaluate the following in patients with n...

journal_title：Annals of internal medicine

authors： Bruno G,Cavallo-Perin P,Bargero G,Borra M,D'Errico N,Pagano G

更新日期：1996-10-15 00:00:00