Inhibitory effect of enamel matrix derivative on osteoblastic differentiation of rat calvaria cells in culture.

abstract：:The characteristic hemagglutination (HA) of Leptotrichia buccalis was used for measuring its attachment to various human cells and for determining if saliva contained hemagglutination inhibition (HI) factors. The microbial strain utilized displayed the characteristic EM morphology of L. buccalis. Sonicated preparation...

journal_title：Journal of periodontal research

authors： Falkler WA Jr,Hawley CE,Mongiello JR

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Regulation of epithelial cell behavior associated with periodontitis is not well elucidated but many responses will ultimately be regulated by growth factor receptors. Using a rat experimental periodontitis model, protein and gene expression of select growth factor receptors in junctional and p...

journal_title：Journal of periodontal research

authors： Ekuni D,Firth JD,Putnins EE

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:A tumor-necrosis factor-alpha (TNF-alpha) antagonist, the WP9QY peptide, was designed based on the crystal structure of the TNF-beta/TNF-receptor complex in order to overcome the disadvantages of macromolecules such as antibodies or soluble receptors by reducing the molecular size of TNF-alpha antagonists. I...

journal_title：Journal of periodontal research

authors： Suzuki Y,Aoki K,Saito H,Umeda M,Nitta H,Baron R,Ohya K

更新日期：2006-04-01 00:00:00

abstract：:The onset and progression of periodontal disease is associated with significant changes in the epithelial component of the attachment complex. From the early to the advanced stages of periodontal disease increased epithelial cell proliferation, migration and invasion into the surrounding connective tissue takes place....

journal_title：Journal of periodontal research

authors： Sanale AR,Firth JD,Uitto VJ,Putnins EE

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Connective tissue grafts are frequently applied, together with Emdogain(®) , for root coverage. However, it is unknown whether fibroblasts from the gingiva and from the palate respond similarly to Emdogain. The aim of this study was therefore to evaluate the effect of Emdogain(®) on fibroblasts...

journal_title：Journal of periodontal research

authors： Gruber R,Stähli A,Miron RJ,Bosshardt DD,Sculean A

更新日期：2015-02-01 00:00:00

abstract：:Using an agar-skim milk gel method, over 300 oral bacterial isolates were tested for their ability to produce trypsin or chymotrypsin inhibitor. Eleven bacterial strains, including seven isolates identified as Bacteroides intermedius, were found to inhibit both proteolytic activities. The inhibitory factors of the 11 ...

journal_title：Journal of periodontal research

authors： Grenier D

更新日期：1991-09-01 00:00:00

abstract：:This study investigates a potential role for TGF beta 1 in the pathogenesis of cyclosporin A-induced gingival overgrowth (CsA-OG). TGF beta 1 was localized immunohistochemically in the connective tissue of both normal gingiva and CsA-OG. Intense staining for TGF beta 1 was detected at the tips of the dermal papillae o...

journal_title：Journal of periodontal research

authors： James JA,Irwin CR,Linden GJ

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The role of water in the etiology of periodontal disease is poorly understood. OBJECTIVES:The objective of this study was to examine the association amongst water softness, risk for periodontitis, and smoking status. METHODS:We examined the association between use of water 'softening and conditioning syste...

journal_title：Journal of periodontal research

authors： Wood N,Johnson RB

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Periodontal disease has been described as playing a role in the atherosclerosis process, and its relation with intimal thickness and vascular endothelial function (EF) has been investigated. The present study sought to determine whether there are differences in parameters of arterial stiffness ...

journal_title：Journal of periodontal research

authors： Nicolosi LN,Lewin PG,Rudzinski JJ,Pompeo M,Guanca F,Rodríguez P,Gelpi RJ,Rubio MC

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Although induction of heme oxygenase-1 by H2O2 has been reported, the protective role of heme oxygenase-1 against the cytotoxic and osteoclastogenic effects of H2O2 have not been elucidated in human periodontal ligament cells. The aim of this work was to investigate the defense mechanism of hem...

journal_title：Journal of periodontal research

authors： Pi SH,Kim SC,Kim HT,Lee HJ,Lee SK,Kim EC

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Obesity has been implicated as a risk factor for several chronic health conditions. Recent studies have reported a relationship between obesity and periodontitis, but few studies have investigated this relationship in adolescents. The purpose of the present study was to investigate the relation...

journal_title：Journal of periodontal research

authors： Ekuni D,Yamamoto T,Koyama R,Tsuneishi M,Naito K,Tobe K

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The jaw bone, unlike most other bones, is derived from neural crest stem cells, so we hypothesized that it may have different characteristics to bones from other parts of the body, especially in the nature of its periosteum. The periosteum exhibits osteogenic potential and has received consider...

journal_title：Journal of periodontal research

authors： Ichikawa Y,Watahiki J,Nampo T,Nose K,Yamamoto G,Irie T,Mishima K,Maki K

更新日期：2015-08-01 00:00:00

abstract：:Cyclosporine (CsA) is a selective immunosuppressant widely used in clinical therapy. Like phenytoin and nifedipine, the drug is associated with gingival overgrowth. This study considers the interaction of CsA and prostaglandin I2 (PGI2), in particular the action of the drug on gingival tissue in vitro and in vivo. The...

journal_title：Journal of periodontal research

authors： Nell A,Matejka M,Solar P,Ulm C,Sinzinger H

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cigarette smoking has detrimental effects on periodontal tissue, and is known to be a risk factor for periodontal disease, including the loss of alveolar bone and ligament tissue. However, the direct effects of cigarette smoking on periodontal tissue remain unclear. Recently, we demonstrated th...

journal_title：Journal of periodontal research

authors： Monnouchi S,Maeda H,Yuda A,Serita S,Wada N,Tomokiyo A,Akamine A

更新日期：2016-12-01 00:00:00

abstract：:To investigate the effect of lipopolysaccharide (LPS) on phagocytic activity of collagen fibrils by periodontal fibroblasts, we studied rat molar gingival connective tissue and periodontal ligament under light and electron microscopy after topical application of LPS (5 mg/ml in physiological salt solution (PS)) on the...

journal_title：Journal of periodontal research

authors： Ijuhin N,Miyauchi M,Ito H,Takata T,Ogawa I,Nikai H

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Occlusal trauma is an important factor that influences the progression of periodontitis, but it is unclear whether occlusal trauma influences periodontal destruction at the onset of periodontitis. We established an experimental periodontitis model with both site-specific loss of attachment and ...

journal_title：Journal of periodontal research

authors： Nakatsu S,Yoshinaga Y,Kuramoto A,Nagano F,Ichimura I,Oshino K,Yoshimura A,Yano Y,Hara Y

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The origin of cells in the mature periodontium, and the location of their progenitors, are still unknown. It is also unknown whether inflammation influences the number and distribution of these cells within the periodontium. Molecules such as STRO-1, CD146 and CD44 have been identified on a var...

journal_title：Journal of periodontal research

authors： Chen SC,Marino V,Gronthos S,Bartold PM

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Forsythia detaching factor (FDF) is a putative virulence factor of Tannerella forsythia that induces detachment of adherent cells and interleukin-8 production in human fibroblasts. The objective of the present study was to clarify the relationship between anti-FDF IgG levels in gingival crevicu...

journal_title：Journal of periodontal research

authors： Onishi H,Arakawa S,Nakajima T,Izumi Y

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Several studies have shown an association between periodontitis and cardiovascular disease (CVD). Atherosclerosis is the major cause of CVD, and a key event in the development of atherosclerosis is accumulation of lipoproteins within the arterial wall. Bacteria are the primary etiologic agents ...

journal_title：Journal of periodontal research

authors： Lönn J,Ljunggren S,Klarström-Engström K,Demirel I,Bengtsson T,Karlsson H

更新日期：2018-06-01 00:00:00

abstract：:The distribution of collagen types I and III was demonstrated in healthy periodontal tissues of the rat and marmoset using immunofluorescent localization after decalcification of the maxillae and mandiblae in 0.2 N HCl. An intense fluorescence in the alveolar bone and cementum matrix, as well as in the soft periodonta...

journal_title：Journal of periodontal research

authors： Romanos GE,Schröter-Kermani C,Hinz N,Wachtel HC,Bernimoulin JP

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:  The junctional epithelium provides the front-line defense against periodontal bacterial infection. The migration of neutrophils into the junctional epithelium might represent a protective reaction against bacterial infections. However, neutrophils penetrate into the junctional epithelium even...

journal_title：Journal of periodontal research

authors： Tsukamoto Y,Usui M,Yamamoto G,Takagi Y,Tachikawa T,Yamamoto M,Nakamura M

更新日期：2012-12-01 00:00:00

abstract：:E-selectin is a cytokine-inducible endothelial glycoprotein which participates in the binding of leukocytes to vascular endothelium. Variable levels of expression of E-selectin have been reported in gingivitis and periodontitis, and two differing concepts of its significance have emerged: either gingival blood vessels...

journal_title：Journal of periodontal research

authors： Pietrzak ER,Savage NW,Xu LJ,Walsh LJ

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Biofilm formation occurs through the events of cooperative growth and competitive survival among multiple species. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans are important periodontal pathogens. The aim of this study was to demonstrate competitive or cooperative interact...

journal_title：Journal of periodontal research

authors： Takasaki K,Fujise O,Miura M,Hamachi T,Maeda K

更新日期：2013-06-01 00:00:00

abstract：:An accumulation of elevated numbers of macrophages (M phi) and Ig producing cells is associated with localized and chronically inflamed gingiva of patients with adult periodontitis. When gingival lymphocytes were isolated from inflamed tissues and examined by flow cytometry, approximately 20-30% of lymphocytes were CD...

journal_title：Journal of periodontal research

authors： Yamamoto M,Fujihashi K,Hiroi T,McGhee JR,Van Dyke TE,Kiyono H

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Long noncoding RNAs (lncRNAs) play critical and complex roles in regulating various biological processes of periodontitis. This bioinformatic study aims to construct a putative competing endogenous RNA (ceRNA) network by integrating lncRNA, miRNA and mRNA expression, based on high-throughput R...

journal_title：Journal of periodontal research

authors： Li S,Liu X,Li H,Pan H,Acharya A,Deng Y,Yu Y,Haak R,Schmidt J,Schmalz G,Ziebolz D

更新日期：2018-08-01 00:00:00

abstract：:Epidermal growth factor (EGF) is a small molecular weight polypeptide which is thought to have important functions in epithelial growth and differentiation and in wound healing. EGF exerts its action on cells through binding to a cell surface receptor. Using immunohistochemistry and a monoclonal antibody (mAb) directe...

journal_title：Journal of periodontal research

authors： Nordlund L,Hormia M,Saxén L,Thesleff I

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The gingival epithelium is a first line of defense against bacterial challenge. E-cadherin (E-cad) plays an important role in cell-cell adhesion as a barrier in the epithelium. Recently, a decrease in the expression of E-cad has been observed in inflamed gingival tissue. The aims of this study ...

journal_title：Journal of periodontal research

authors： Abe-Yutori M,Chikazawa T,Shibasaki K,Murakami S

更新日期：2017-02-01 00:00:00

abstract：:This study was designed to study wound strength at the dentine/connective tissue interface and at the bone/connective tissue interface following full thickness flap surgery. Flaps of uniform dimension were outlined in four young adult beagle dogs using a standardised double bladed knife and vertical incisions 10 mm ap...

journal_title：Journal of periodontal research

authors： Werfully S,Areibi G,Toner M,Bergquist J,Walker J,Renvert S,Claffey N

更新日期：2002-10-01 00:00:00

abstract：:Effects of lathyrogens such as aminoacetonitrile (AAN), beta-aminopropionitrile (BAPN) and cysteamine--known inhibitors of cross-linking of collagen--on the mechanical strength of the periodontal ligament of the rat mandibular first molar were examined by measuring the ultimate load required to extract the tooth from ...

journal_title：Journal of periodontal research

authors： Ohshima S,Nakamura G,Chiba M

更新日期：1989-09-01 00:00:00

abstract：:Quantitative assessment of osseous changes attributable to periodontal disease is made possible by digital subtraction radiography. Tissues through which x rays travel to produce dental radiographs essential to this process alter the energy spectrum of the beam such that calibration errors result when densitometry is ...

journal_title：Journal of periodontal research

authors： Webber RL,Tzukert A,Ruttimann U

更新日期：1989-01-01 00:00:00