Abstract:
:We studied platelet half-life (T/2), plasma thromboxane B2-levels (TXB2) and circulating endothelial cells in 107 patients with a mean age of 63 +/- 6.8 years and angiographically proven peripheral vascular disease (PVD). Patients were divided into 4 groups according to Fontaine but also according to additional clinical manifestations of atherosclerosis like coronary heart disease (CHD) and cerebrovascular disease (CVD). Furthermore, the influence of sex and smoking was investigated. Compared to patients without atherosclerotic manifestations we could detect an enhanced platelet consumption measured as shortened platelet half-life time (79.2 +/- 9.1 vs 100.9 +/- 5.6 hours, p less than 0.001 and an increased platelet activity measured as increased TXB2-plasma levels (51.6 +/- 20.9 vs 23.2 +/- 11.2 ng/ml, p less than 0.001). Correspondingly, the amount of circulating endothelial cells was increased 45.2 +/- 25.7 vs 20.3 +/- 23.4, p less than 0.001). Patients with PVD who smoked had the shortest actual platelet half-life, the highest TXB2 plasma levels and the greatest amount of circulating endothelial cells compared to non-smoking patients and controls. Patients with clinical stage IV according to Fontaine had the shortest platelet half-life, the highest TXB2 plasma levels and the greatest amount of circulating endothelial cells compared to the other clinical stages. Analyzing the influence of additional clinical manifestations of atherosclerosis we could detect only in patients with PVD and CHD significant differences compared to the other groups.
journal_name
Angiologyjournal_title
Angiologyauthors
Sinzinger H,Fitscha P,Peskar BAdoi
10.1177/000331978603700207subject
Has Abstractpub_date
1986-02-01 00:00:00pages
112-8issue
2eissn
0003-3197issn
1940-1574journal_volume
37pub_type
杂志文章相关文献
ANGIOLOGY文献大全abstract::Pentoxifylline was first introduced in Germany twenty years ago. Today it is the best researched oral drug for intermittent claudication. A total of seventeen placebo-controlled trials could be retrieved from the world literature. The majority of these studies show that pentoxifylline will prolong the walking distance...
journal_title:Angiology
pub_type: 杂志文章,评审
doi:10.1177/000331979404500502
更新日期:1994-05-01 00:00:00
abstract::The incidence of contrast-induced acute kidney injury (CI-AKI) is rising due to increased use of coronary angiography and percutaneous coronary intervention. Many agents, including statins, have been evaluated in several studies for the prevention of CI-AKI. To date, there have been 14 prospective randomized studies r...
journal_title:Angiology
pub_type: 杂志文章,评审
doi:10.1177/0003319714549556
更新日期:2015-09-01 00:00:00
abstract::This study aimed at evaluating the changes in platelet-activating factor (PAF) and its metabolic enzymes over a 6-week follow-up period in patients with newly diagnosed heart failure ([HF] n = 12) compared with age-, sex-, and BMI-matched apparently healthy volunteers (n = 10). The PAF, its key biosynthetic enzymes (l...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319712458536
更新日期:2013-10-01 00:00:00
abstract::Not only antiphospholipid antibodies (aPLs) but also other factors should be considered in assessing the risk of thrombosis development in patients with systemic lupus erythematosus (SLE) and antiphospholipid antibodies (aPLs). The kinds of risk factors, including past history of thrombotic event (PHTE), hypertension,...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970505600512
更新日期:2005-09-01 00:00:00
abstract::Beta blockers are one of the oral agents shown to decrease cardiovascular morbidity and mortality rates in randomized, controlled trials, and hence, they are widely used for the management of many cardiovascular situations. In terms of side effects there are 3 major modes of action: (1) contraction of smooth muscles, ...
journal_title:Angiology
pub_type: 杂志文章,评审
doi:10.1177/000331970205300617
更新日期:2002-11-01 00:00:00
abstract::Lower mortality rates from coronary heart disease and higher levels of serum high-density lipoprotein cholesterol (HDL-C) have been observed in populations residing at high altitude. However, this effect has not been investigated in Arab populations, which exhibit considerable genetic homogeneity. We assessed the rela...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319714544355
更新日期:2015-07-01 00:00:00
abstract::The authors assessed whether measurements obtained by Judkins-style Doppler catheters are comparable to those achieved with the intracoronary Doppler technique in 42 patients with normal coronary arteries on angiography (19 syndrome X and 23 heart transplant patients). Resting coronary flow velocity and response to a ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979304401203
更新日期:1993-12-01 00:00:00
abstract::The idea of cerebrovascular injury in cases of thromboangiitis obliterans was not strange to Leo Buerger, but Jäger (1932), as well Lindenberg and Spatz (1939), first established it. The aim of this study was to investigate the hemodynamics in the basal cerebral arteries by means of transcranial Doppler in patients wi...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979704800609
更新日期:1997-06-01 00:00:00
abstract::Thromboangiitis obliterans (TAO) is an occlusive vascular disease traditionally known to be almost exclusive to young male smokers. The disease was considered to be extremely rare in women, seen only as isolated, novel case reports in the literature. In the past decade, however, a dramatic increase in the incidence of...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979304400704
更新日期:1993-07-01 00:00:00
abstract::Intravascular ultrasound (IVUS) frequently reveals plaque formation at sites with a normal angiographic appearance. However, whether angiographically normal coronary arteries undergo adaptive expansion in vivo remains uncertain. The authors studied 12 patients (11 men, 1 woman; mean age fifty-three +/- ten years [mean...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979604700804
更新日期:1996-08-01 00:00:00
abstract::After a review of the history of intra-arterial treatment, our personal experience with a complex treatment of 900 cases of arteriopathy of the lower extremities is reported. The conservative treatment includes stopping smoking, plus diet, exercise, B and C vitamins, and administration of 1% xylocaine (lidocaine) in t...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978003100401
更新日期:1980-04-01 00:00:00
abstract::Every day, thousands of people in the United States receive polycyclic antidepressants (PCAs) prescribed by their primary care physicians. We have examined the cardiovascular manifestations of polycyclic antidepressants in 14 patients with primary depression receiving various antidepressant drugs for a period of six m...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978603701003
更新日期:1986-10-01 00:00:00
abstract::An 82-year-old man developed acute inferior myocardial infarction. Emergent coronary angiography demonstrated thrombotic occlusion in the right coronary artery. Intracoronary thrombolytic therapy was performed with successful recanalization. However, circumferential dissection with luminal stenosis was revealed at the...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979804900112
更新日期:1998-01-01 00:00:00
abstract::The efficacy, tolerance and safety of iloprost, a stable analogue of carbaprostacyclin, were evaluated in 7 patients with peripheral arterial insufficiency at stage II of Fontaine's classification. After washout, placebo was infused intravenously for seven days, then iloprost was given by a six-hour intravenous infusi...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978904001009
更新日期:1989-10-01 00:00:00
abstract::In this double-blind, crossover study the authors have validated stroke volume determination by impedance cardiography against the pulsed Doppler echocardiographic method in elderly hypertensives. They found a good correlation between the stroke volume values obtained by the two methods over a range of values from 30 ...
journal_title:Angiology
pub_type: 临床试验,杂志文章
doi:10.1177/000331979104200807
更新日期:1991-08-01 00:00:00
abstract::The possible associations between coronary heart disease (CHD) and peripheral arterial disease (PAD), detected by echo-Doppler analysis, with restriction fragment length polymorphism (RFLP) of apo AI/CIII cluster and apo B gene were investigated in a group of men with premature CHD (n = 39) and in a control group of m...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979304401004
更新日期:1993-10-01 00:00:00
abstract::A thorough search for the natural history of arteriosclerosis involving the cerebrum, aorta, and peripheral vessels has been made. The disease's rate of progress has been studied anatomically, clinically, radiologically, and plethysmographically. We conclude that arteriosclerosis is usually associated with other disea...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331977802900402
更新日期:1978-04-01 00:00:00
abstract:CONCLUSIONS:The last decade, patients with AMI became older with increased burden of CVRFs. Framingham risk score increased among patients with NSTEMI and decreased in patients with STEMI. These trends impact on risk stratification and secondary prevention programs. ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319718816479
更新日期:2019-07-01 00:00:00
abstract::We used the National Heart, Lung, and Blood Institute Limited Access Dataset of Prevention of Events with Angiotensin-Converting Enzyme Inhibition (PEACE) Trial (n = 8290) which included patients with stable coronary artery disease (CAD) and preserved ejection fraction (>40%). We identified risk factors for the develo...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319711398650
更新日期:2011-08-01 00:00:00
abstract::Fasting plasma insulin concentrations were obtained in 82 patients (51 men and 31 women), mean age 60 +/- 11 years, with a body mass index >25 kg/m(2) who had coronary angiography because of suspected symptomatic coronary artery disease (CAD). Obstructive CAD was diagnosed if there was >50% obstruction of > or =1 vess...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970505600302
更新日期:2005-05-01 00:00:00
abstract::To date, technical experience reported in the literature is very limited on angioplasty in patients with anomalous coronary arteries. Balloon angioplasty may be a more favorable approach for revascularization in these vessels. A major factor is selection of the guiding catheter. The authors report 4 patients with seve...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979604700112
更新日期:1996-01-01 00:00:00
abstract::We investigated the relation between diabetic autonomic neuropathy (DAN) and left ventricular (LV) function in 59 patients with type 2 diabetes mellitus (T2DM) free of coronary artery disease (CAD) or hypertension. Diabetic autonomic neuropathy was established by ≥2 abnormal autonomic nervous function tests. Left vent...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319713510966
更新日期:2014-11-01 00:00:00
abstract::Effect of atrial fibrillation (AF) on short- and long-term outcomes in heart failure (HF) is controversial. Accordingly, we examined this relationship in a national multicenter project using data from the Hearts Function Assessment Registry Trial in Saudi Arabia that studied the clinical features and outcomes of patie...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319717711764
更新日期:2018-02-01 00:00:00
abstract::The value of digital systolic blood pressure (DBP) and flow (DBF) measurements for a quantitative diagnosis of Primary Raynaud's Phenomenon (PRP) was evaluated by comparing the results obtained in 10 patients and 20 normals. Digital skin temperature (DST), DBP and brachial systolic blood pressure (BBP) and DBF were me...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978603700307
更新日期:1986-03-01 00:00:00
abstract::We examined whether high-sensitivity C-reactive protein (hsCRP) ≥2.0 mg/L was associated with increased intima-media thickness (IMT), plaque burden, and plaque echolucency in carotid arteries. Women (n = 635) from a population sample of 64-year-old females with varying degrees of glucose tolerance underwent risk facto...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319710370959
更新日期:2010-11-01 00:00:00
abstract::The purpose of this study was to compare the gender and age-related differences in vascular reactivity in healthy men and women across a wide age range. Fifty-seven men and 61 women between 20 and 89 years of age, free of cardiovascular disease and risk factors, were categorized into younger (20-39 years), middle-aged...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319706295474
更新日期:2006-12-01 00:00:00
abstract::An eighty-one-year-old woman received quinidine in order to convert atrial fibrillation to a sinus rhythm. The patient developed a prolonged QT interval on the EKG, as well as episodes of torsade de pointes. With the administration of intravenous magnesium sulfate, the abnormal rhythm was suppressed within minutes. Th...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979004100712
更新日期:1990-07-01 00:00:00
abstract::Only a few angiographic studies have correlated the presence and severity of coronary artery disease with atherosclerosis in other arteries. The presence of disease in more than 1 area clearly has important implications on management. One hundred and seventy eight patients had angiographic evaluation of their peripher...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970305400111
更新日期:2003-01-01 00:00:00
abstract::Accuracy in the diagnosis of lower extremity deep venous thrombosis (DVT) by physical examination and impedance plethysmography (IPG) is reviewed. Physical examination proved unreliable in distinguishing patients with and without acute disease. Swelling in the leg was, however, more prevalent in patients with DVT. The...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978703800305
更新日期:1987-03-01 00:00:00
abstract::Low albumin and the albumin-globulin ratio (AGR) were associated with vascular adverse events. Our study explores the AGR as a predictor of mortality after non-ST-segment elevation myocardial infarction (NSTEMI). In an observational study of 570 NSTEMI patients admitted to a tertiary center between 2004 and 2006, pati...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319712436577
更新日期:2013-02-01 00:00:00