Increased insulin binding is not involved in the improved insulin effectiveness of gestational diabetics after hypoenergetic dieting.

abstract：AIMS:The aim of this study was to investigate whether the polymorphism of DDAH2 is associated with type 2 diabetes and hypertension in Korean population. METHODS:Total 605 subjects were included in this study: 403 patients with type 2 diabetes and 202 non-diabetic control subjects. The SNP rs805304 and rs2272592 in DD...

journal_title：Diabetes research and clinical practice

authors： Seo HA,Kim SW,Jeon EJ,Jeong JY,Moon SS,Lee WK,Kim JG,Lee IK,Park KG

更新日期：2012-10-01 00:00:00

abstract：:Current smoking was associated with low insulin secretion and high 30-min plasma glucose (PG), 60-min PG, and area under the curve of PG, whereas current smoking was not associated with fasting PG and 2-h PG levels in both individuals with normoglycemia and individuals with pre-diabetes in a large-scale community-base...

journal_title：Diabetes research and clinical practice

authors： Morimoto A,Tatsumi Y,Miyamatsu N,Sonoda N,Deura K

更新日期：2014-11-01 00:00:00

abstract：:Glomerular hyperfiltration plays a pathogenic role in the early stages of diabetic nephropathy. Experimental studies in laboratory animals suggest that nitric oxide (NO) might be involved in the pathogenesis of glomerular hyperfiltration. We performed a cross-sectional study to determine the relationship between diabe...

journal_title：Diabetes research and clinical practice

authors： Hiragushi K,Sugimoto H,Shikata K,Yamashita T,Miyatake N,Shikata Y,Wada J,Kumagai I,Fukushima M,Makino H

更新日期：2001-09-01 00:00:00

abstract：:There is scant knowledge on the changes in renal histological findings in type 1 diabetic patients those initially had nephrotic proteinuria and decreased renal function and later had complete remission of diabetic nephropathy by multifactorial treatment (MFT). A 44-year-old Japanese type 1 diabetic woman (duration of...

journal_title：Diabetes research and clinical practice

authors： Haraguchi K,Hara S,Ubara Y,Tanaka S,Nukui I,Shimura H,Ohashi K,Kobayashi T

更新日期：2009-03-01 00:00:00

abstract：:We examined cross-sectional associations of sex hormone binding globulin (SHBG) with glucose among women recent GDM (n=55). SHBG was associated with fasting glucose levels before and after adjustment for covariates (p=0.015), but not with 2-h glucose. We conclude SHBG should be explored in prospective studies in GDM w...

journal_title：Diabetes research and clinical practice

authors： Kim C,Sen A,Osborne E,Lee JM,Richardson CR

更新日期：2011-09-01 00:00:00

abstract：UNLABELLED:Obesity was considered to be one of the causes of non-insulin-dependent diabetes mellitus (NIDDM). However, the mechanism responsible for obesity has not yet been fully elucidated. In this study, we first examined the relationship between food intake amount and obesity in a NIDDM model animal, and then we fo...

journal_title：Diabetes research and clinical practice

authors： Luan Y,Hirashima T,Man ZW,Wang MW,Kawano K,Sumida T

更新日期：2002-08-01 00:00:00

abstract：:The understanding that statins reduce but not eliminate the cardiovascular risk associated with disturbed lipid metabolism and the existence of forms of dyslipidemia that are unresponsive or only partially responsive to statins have led to the development of many novel lipid-lowering drugs. Accumulating evidence sugge...

journal_title：Diabetes research and clinical practice

authors： Tsimihodimos V,Elisaf M

更新日期：2018-03-01 00:00:00

abstract：AIMS:To examine predictors of quality of life gains among people with type 1 diabetes following the Dose Adjustment for Normal Eating (DAFNE) self-management training programme. METHODS:Clinical and questionnaire data were collected from 437 patients from 6 hospital centres before, and 18 months post-DAFNE interventio...

journal_title：Diabetes research and clinical practice

authors： Byrne M,Newell J,Coffey N,O' Hara MC,Cooke D,Dinneen SF

更新日期：2012-11-01 00:00:00

abstract：AIMS:Central obesity, a prominent feature of metabolic syndrome (MetS), is commonly assessed by gender- and ethnicity-specific waist circumference (WC) cut-off values. Since 2006, the recommended WC cut-offs by the International Diabetes Federation (IDF) for Europeans are used in Iran because of limited data availabili...

journal_title：Diabetes research and clinical practice

authors： Esteghamati A,Ashraf H,Rashidi A,Meysamie A

更新日期：2008-10-01 00:00:00

abstract：:Hyperglycemia causes vascular complications of diabetes possible by the activation of protein kinase C (PKC). We have provided substantial evidence that activation of PKC can lead to a whole host of vascular dysfunction in diabetes. The activation of PKC induced by hyperglycemia appears to be due to an increase in dia...

journal_title：Diabetes research and clinical practice

authors： Bursell SE,King GL

更新日期：1999-09-01 00:00:00

abstract：:Four patients who exhibited the greatest decline in the estimated glomerular filtration rate [12.3-23.5 ml/min/1.73 m(2)/year] among 320 patients with type 2 diabetes and were followed for a median of 6.8 years had several clinical features in common, including marked albuminuria, microhematuria, retinopathy and poor ...

journal_title：Diabetes research and clinical practice

authors： Sakata M,Oniki K,Kita A,Kajiwara A,Uchiyashiki Y,Saruwatari J,Yoshida A,Jinnouchi H,Nakagawa K

更新日期：2013-05-01 00:00:00

abstract：AIMS:This study was designed to compare the risk of long-term health outcomes, including microvascular, macrovascular complications and mortality, across 4 cohorts: triple-goal, dual-goal, single-goal, and no-goal achievers. METHODS:A retrospective cohort of 53,120 patients with T2DM were identified (97.51% male, 61.4...

journal_title：Diabetes research and clinical practice

authors： Shi Q,Liu S,Krousel-Wood M,Shao H,Fonseca V,Shi L

更新日期：2018-06-01 00:00:00

abstract：AIM:We previously identified the transcription factor activating enhancer-binding protein-2beta (AP-2beta) gene as a new candidate for conferring susceptibility to type 2 diabetes. To ascertain the possible involvement of AP-2beta in the pathogenesis of type 2 diabetes we examined the effects of AP-2beta on glucose-ind...

journal_title：Diabetes research and clinical practice

authors： Tsukada S,Kobayashi MA,Omori S,Unoki H,Maeda S

更新日期：2009-09-01 00:00:00

abstract：AIMS:Diabetic patients require care from a variety of health care providers, but little is known about their actual use of health care. Aims of this study were to (1) obtain information on health care use by diabetic patients in the Netherlands, (2) distinguish patterns of health care utilisation among these patients, ...

journal_title：Diabetes research and clinical practice

authors： El Fakiri F,Foets M,Rijken M

更新日期：2003-09-01 00:00:00

abstract：:Numerous studies with compelling evidence had shown a clear relationship between dyslipidaemia and cardiovascular (CV) events in patients with diabetes mellitus. This was an observational study based on secondary data from the online registry database Adult Diabetes Control and Management (ADCM) looking into the deter...

journal_title：Diabetes research and clinical practice

authors： Chew BH,Ismail M,Lee PY,Taher SW,Haniff J,Mustapha FI,Bujang MA

更新日期：2012-06-01 00:00:00

abstract：:In an attempt to clarify the mechanism of lipid metabolism during pregnancy, alpha 1-acid glycoprotein (alpha 1-AG) was analyzed in normal and diabetic pregnant women. Seventy-two determinations of serum alpha 1-AG levels were performed in 18 diabetic pregnant women and 82 determinations in 82 normal pregnant women in...

journal_title：Diabetes research and clinical practice

authors： Honda M,Omori Y,Minei S,Oshiyama T,Shimizu M,Sanaka M,Kohama T,Nakabayashi M,Hirata Y

更新日期：1990-10-01 00:00:00

abstract：:Amputation has been known to be a rare adverse event of sodium glucose co-transporter-2 (SGLT2) inhibitors. It remains unclear whether the SGLT2 inhibitor as a class or specific categories of the SGLT2 inhibitors are linked with an increased risk of amputation. The objective of this meta-analysis was to investigate th...

journal_title：Diabetes research and clinical practice

authors： Miyashita S,Kuno T,Takagi H,Sugiyama T,Ando T,Valentin N,Shimada YJ,Kodaira M,Numasawa Y,Kanei Y,Bangalore S

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:To compare cardiovascular risk factors and LDL particle size in well-controlled Type 2 diabetes mellitus and normal subjects. METHODS:Ninety-three Type 2 diabetic males and 186 age-matched, male controls were studied. Glycaemic control was stable for at least 3 months prior to recruitment. None were on insu...

journal_title：Diabetes research and clinical practice

authors： Tan CE,Chew LS,Chio LF,Tai ES,Lim HS,Lim SC,Jayakumar L,Eng HK,Packard CJ

更新日期：2001-02-01 00:00:00

abstract：:Cultured cells derived from hamster insulinoma (In-111 R1 cells) were placed in 1.4 M dimethyl sulfoxide (Me2SO)-containing RPMI 1640 at 20 degrees C for 20 min. They were frozen to -40 degrees C at a cooling rate of 1.0 or 0.5 degrees C/min, subsequently to -80 degrees C at 3 degrees C/min with a programmable freezer...

journal_title：Diabetes research and clinical practice

authors： Ishihara K,Taniguchi H,Ejiri K,Baba S

更新日期：1991-02-01 00:00:00

abstract：AIM:To assess efficacy/safety of initial linagliptin/metformin single-pill combination (SPC) therapies versus individual drug components over 24weeks in treatment-naïve Asian patients with type 2 diabetes mellitus and insufficient glycemic control. METHODS:Patients (initial glycated hemoglobin [HbA1c] ⩾7.5% to <11.0% ...

journal_title：Diabetes research and clinical practice

authors： Mu Y,Pan C,Fan B,Hehnke U,Zhang X,Zhang X,Wang X,Liu J,Zhang Y,Du J,Ma J,Gong Y

更新日期：2017-02-01 00:00:00

abstract：:The lesions of diabetic nephropathy have been considered to be irreversible. Pancreas transplantation is the only available treatment able to restore long-term normoglycemia without exposing the patients to the risks of severe hypoglycemia; thus allowing testing the effects of very long-term euglycemia in preventing, ...

journal_title：Diabetes research and clinical practice

authors： Fioretto P,Barzon I,Mauer M

更新日期：2014-06-01 00:00:00

abstract：AIMS:The aim of the study was to determine physicians' knowledge of specific concepts generally implicated in the pathophysiology of type 2 diabetes (T2D). METHODS:A multiple choice online survey was completed by 847 physicians, of which 516 were engaged in primary care (PCP) and 331 in specialized care (SCP) in the U...

journal_title：Diabetes research and clinical practice

authors： Busse FP,Denti V,Stumvoll M

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:Muscle mass and function are among the most relevant factors that contribute to an optimal quality of life, and are strong predictors of mortality in the elderly. Loss of lean tissues and deterioration of muscle function have been described as one of the many complications of type 2 diabetes mellitus (DM2)...

journal_title：Diabetes research and clinical practice

authors： Guerrero N,Bunout D,Hirsch S,Barrera G,Leiva L,Henríquez S,De la Maza MP

更新日期：2016-07-01 00:00:00

abstract：AIMS:Media calcification is a predictor of cardiovascular mortality in type 2 diabetes mellitus (T2DM). Undercarboxylation of some vitamin K-dependent proteins, due to genetic polymorphisms of VKORC1, can lead to calcification. We examined a potential association between VKORC1 -1639 G>A polymorphism and T2DM and, also...

journal_title：Diabetes research and clinical practice

authors： Tavridou A,Petridis I,Vasileiadis M,Ragia G,Heliopoulos I,Vargemezis V,Manolopoulos VG

更新日期：2011-11-01 00:00:00

abstract：:Amelioration of albuminuria may be related to specific constellations of risk factors including race and dyslipidaemia. Circulating cholesterol could mitigate the beneficial effect of antihypertensive therapy. We assessed whether cholesterol affected the remission of urinary albumin in patients with type 2 diabetes of...

journal_title：Diabetes research and clinical practice

authors： Earle KA,Harry D,Zitouni K

更新日期：2008-01-01 00:00:00

abstract：AIM:Studies on the effect of Ramadan diurnal intermittent fasting (RDIF) on glucometabolic markers have yielded conflicting results. We conducted ameta-analysis to estimate the effect size for changes in glucometabolic markers in healthy, non-athletic Muslims during Ramadan, and to assess the effect of variable covaria...

journal_title：Diabetes research and clinical practice

authors： Faris MA,Jahrami H,BaHammam A,Kalaji Z,Madkour M,Hassanein M

更新日期：2020-07-01 00:00:00

abstract：:We evaluated the effects of thromboxane synthetase inhibitor, OKY-046, on urinary albumin and prostaglandin (PG) excretion in 14 patients with non-insulin-dependent diabetes mellitus (NIDDM). Urinary excretion of 6-keto-PGF1 alpha (a stable metabolite of PGI2), TXB2 (a stable metabolite of TXA2) and PGE2 in NIDDM pati...

journal_title：Diabetes research and clinical practice

authors： Tajiri Y,Inoguchi T,Umeda F,Nawata H

更新日期：1990-11-01 00:00:00

abstract：:Self-monitoring of blood glucose (SMBG) in type 2 diabetic patients was compared across 14 countries. There was an unexpectedly high SMBG-use in non-insulin-treated patients. Reimbursement polices differed by country, region, insurance status, and patient income. More rigorous and systematic data collection is needed ...

journal_title：Diabetes research and clinical practice

authors： SMBG International Working Group.

更新日期：2008-12-01 00:00:00

abstract：:To characterise the relationship between diurnal blood pressure and the subsequent increase of urinary albumin excretion (UAE) in normotensive normoalbuminuric type 1 diabetic patients, ambulatory blood pressure monitoring (ABPM) was performed in 53 patients, who were then followed for 5 years. Albumin excretion rate ...

journal_title：Diabetes research and clinical practice

authors： Lengyel Z,Rosivall L,Németh C,Tóth LK,Nagy V,Mihály M,Kammerer L,Vörös P

更新日期：2003-12-01 00:00:00

abstract：:Proteinuria is a well known risk factor for cardiovascular morbidity. There has been no report on cardiovascular morbidity in Indian NIDDM patients with proteinuria. Hence this study has been undertaken to estimate the prevalence of cardiovascular diseases (CVD) in South Indian NIDDM with proteinuria. We studied two g...

journal_title：Diabetes research and clinical practice

authors： Viswanatham V,Snehalatha C,Mathai T,Jayaraman M,Ramachandran A

更新日期：1998-01-01 00:00:00