Abstract:
:Contrast sensitivity (CS) emerged more than 30 years ago as an alternative to traditional acuity testing, and recently it has become the focus of attention in the field of neurotoxicology. CS testing may be useful for detecting defects in oculoneural processing and therefore possible chemical-induced neurotoxicity, such as solvent-induced encephalopathy. The authors' objective in this article is to introduce the concept of CS and CS testing, summarize recent reports describing its use in occupational and environmental toxicology, and challenge the validity of CS testing in its present state as a toxicological assessment. Although CS testing appears to be an attractive and cost-effective screening tool for identifying possible neurotoxicity, additional work will be required before it can become a meaningful and widely accepted diagnostic tool.
journal_name
Arch Environ Occup Healthjournal_title
Archives of environmental & occupational healthauthors
Waksman JC,Brody Adoi
10.3200/AEOH.62.4.177-181subject
Has Abstractpub_date
2007-01-01 00:00:00pages
177-81issue
4eissn
1933-8244issn
2154-4700pii
6WR020G641JP6005journal_volume
62pub_type
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