Abstract:
:Environmental factors appear to be important in the etiology of testicular cancer. In this study, the authors identified some risk factors for testicular cancer, paying particular attention to prenatal and early life exposure to endocrine-disrupting chemicals (EDCs). Using a questionnaire, the authors obtained information on male participants' environmental and occupational exposures during adolescence and adulthood. A multivariate logistic regression analysis of 103 cases and 215 controls showed an association between seminoma and nonseminoma and hobby activities that potentially involved the use of EDCs (eg, paints, glues, or solvents). Rural residence during adolescence was associated with all histological types of testicular cancer and with seminoma. No association was found with occupational exposures of the subjects. This study's findings also confirm previously identified risk factors, such as history of cryptorchidism and undescended testicle, high educational level, and low birth weight, and it gives some support to the hypothesis of a possible association between EDC exposures and testicular cancer.
journal_name
Arch Environ Occup Healthjournal_title
Archives of environmental & occupational healthauthors
Nori F,Carbone P,Giordano F,Osborn J,Figà-Talamanca Idoi
10.3200/AEOH.61.2.87-95subject
Has Abstractpub_date
2006-03-01 00:00:00pages
87-95issue
2eissn
1933-8244issn
2154-4700journal_volume
61pub_type
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journal_title:Archives of environmental & occupational health
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